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An Improved, Completely Herbal And Chemical Free Cough And Cold Formulation And A Process Of Preparing Thereof

Abstract: An improved cough and cold syrup composition and formulation process is disclosed here. The present invention provides improved cough and cold syrup containing Salvia officinalis leaf extract, Cetrariaislandica extract, Thyme fluid extract, Menthol, purified water; Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerin. The improved cough and cold syrup disclosed here provides the combination of herbs that helps sooth the throat to ease coughing and promote restful sleep. It helps “expel” the mucous by loosening and making it easier to cough up. It provides antibacterial effect that helps fight inflammation in the mouth and throat and eliminate accumulated mucus.

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Patent Information

Application #
Filing Date
26 October 2020
Publication Number
17/2022
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
info@knowledgentia.com
Parent Application

Applicants

SPV LABORATORIES PVT. LTD
20, Arihant Nagar, 2nd Floor, Punjabi Bagh (West), N.D.-110026, India

Inventors

1. Sanchit Garg
20, Arihant Nagar, 2nd Floor, Punjabi Bagh (West), N.D.-110026, India

Specification

The present invention relates to the field of herbal natural formulations.
More particularly, the present invention relates to a completely herbal, non-toxic, chemical free cough and cold syrup.
Even more particularly the present invention provides a cough and cold syrupformulation and a processof preparing thereof.
The formulation of present invention comprises Salviaofficinalis leaf extract, Cetraria islandica extract, Thyme fluid extract.
Combination of such herbs helps sooth the throat to ease coughing and promote restful sleep. It helps “expel” the mucous by loosening it up and making it easier to cough up.
Background of the invention:
As per prior observations, many Bronchitis Syrup are available in the market but they do not fulfil the requirements of present day’s consumers. Few examples of such syrup are mentioned below.
Torex Herbal cough syrup- Contains 20 herbs mainly Vasa, Tulsi, Sunthi, Mulethi, Kali Mirchi, Pudina etc. Used for quick relief from cough.
Tuss Nil Syrup- Mainly contains Vasa, sunthi and ksamarda for seasonal cough and cold.
Kasni cough management Syrup-Contains pippali, sonth, Tulsi, Mulethi, Kant kari. Dalchini etc.
Herbion cough syrup contains single ingredient Cetrariaislandicawhich are responsible for covering, protecting and moisturizing the mucosa of the mouth and throat. It helps to relieve irritation caused by dry cough.
Sage Kuf-Kure: is a blend of so many ayrudichers in which sage is one there claim isfor curing the problems of Branchialspasam, Branchities, cough.
By thereference of patent Number DE3229086(A1)by WICHERT GEB SCHUERMANN ANNETTE [DE] dated 1982-08-04, titled” Medicine for coughs and other disorders of the respiratory organs of horses, and feedstuff for horses produced using the same”.This invention provides an improved medicine for coughs and other disorders of the respiratory organs of horses, as well as feedstuffs for horses produced using the same, the invention envisages the use of Cetrariaislandica (Iceland moss lichen) and/or Lichen islandicus (reindeer lichen) as plant active ingredients. Where the medicine also contains other plant active ingredients, Cetrariaislandica and/or Lichen islandicus represent the principal active constituents thereof. Furthermore, envisaged according to the invention is a feedstuff for horses which contains the medicine as component.
By thereference of patent Number KR20040010390(A)by LOTTE CO LTD dated 2002-07-26, titled “Anti-influenza virus agent and composition containing the same and food or drink”. This invention provides an anti-influenza virus agent which contains a daily highly safe plant extract, exhibits a highly inhibiting effect against the infection of influenza viruses, and is free from a side effect, to provide a composition containing the same, and to provide a food or drink containing the same. CONSTITUTION: The plant from which the active ingredient is extracted includes Rubusidaeus, Fragariavesca, Rubusfruticosus, Ficuscarica, Chenopodium album, Agrimoniaeupatoria, Eucalyptus globules, Prunuspersica, Maluspumila, Viola odorata, Lindera umbellate, Paulliniacupana, Buddleia officinalis, Commelinacommunis, Capsellabursapastoris, Rabdosia japonica, Fragariavesca, Marrubiumvulgare, Althaea officinalis, Plantagoasiatica, Aloysiatriphylla, Achilleamillefolium, Cetrariaislandica, Hydrangeserrata, and Petasitesjaponicas.
By thereference of patent Number RU2006120323(A)by OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOST'JU "ROSBIO", ; ENIKEEVA RIMMA AJRATOVNAdated2006-06-02, titled “EXTRACT OF FICO AND MICRBIONATE Cetrariaislandica (L.) Ach. DRY AND HIS TABLET FORM”. This invention relates to an agent used in treatment and prophylaxis of pulmonary diseases, among them tuberculosis. Agent is prepared as a tablet comprising a core and envelope wherein a core comprises lichen thallusCetrariaislandica (L.) Ach.dry extract as active substances that comprises complex of biologically active substances extracted with aqueous ethyl alcohol in the definite concentration and wherein extract comprises polysaccharides in the definite amount as measured for the glucose content. As special additives the agent comprises lactose, methylcellulose and calcium stearate taken in the definite ratio of components. Envelope is made on basis of hydroxypropylcellulose and titanium dioxide, for example, of sort white "Spektrablend". Agent is effective in prophylaxis and treatment of pulmonary diseases, among them, tuberculosis disease, it retains better sorption properties and elicits detoxification properties, releases active substance easily and provides high bioavailability. Invention is used in prophylaxis and treatment of pulmonary diseases, among them, tuberculosis disease.
By thereference of patent Number RU2412718(C1)by ZD EHKOLOGICHESKOJ TEKHN I EHKOPITANIJA DIOD AOOT [RU] dated 2009-10-21, titled “Medication for treatment and prevention of acute respiratory viral and bacterial diseases and method of obtaining it”.This invention relates to field of chemical-pharmaceutical and food industry, namely to field of creating liquid forms of medications and biologically active food additives, with wide spectrum of pharmacological action, namely general health-improving, anti-inflammatory, antimicrobial, antiviral and immunomodelling and antioxidant action. Claimed medication for treatment and prevention of upper airways diseases is made in form of syrup of thallus of Island moss Cetrariaislandica (L.) Ach., enriched with complex of biologically active substances, including polysaccharides and lichen acids. Also claimed is method of obtaining medicinal syrup of Island moss. Vegetable raw material before extraction is preliminarily crushed and extraction is carried out with syrup of various concentrations with its further filtering. The method ensures obtaining of final product - syrup of Island moss, maximal substance extraction, as well as preservation of biologically active substances (BAS) in syrup (polysaccharides, lichen acids) during long term in native state, thus, ensuring high medication efficiency.
By thereference of patent Number CN101869617 (A) by DECAI SUdated2009-04-27, titled “Traditional Chinese medicine for treating cough”.The invention discloses a transitional Chinese medicine for treating cough, which is characterized in that a Chinese medicinal preparation is prepared from the following medicinal materials by weight: 10 to 20 grams of wall spider, 5 to 15 grams of ephedra, 10 to 20 grams of apricot kernel, 10 to 20 grams of pantain seed, 10 to 20 grams of thinleaf milkwort root-bark, 10 to 20 grams of stiff silkworm, 10 to 25 grams of fructusbardanae, 10 to 20 grams of sulforaphen, 10 to 20 grams of inula flower, 10 to 20 grams of Chinese angelica, 10 to 20 grams of mulberry bark, 10 to 20 grams of liquorice root, 10 to 20 grams of platycodon root, 10 to 20 grams of dried orange peel, 10 to 20 grams of weeping forsythia, 10 to 20 grams of root of red-rooted salvia, 10 to 20 grams of baical skullcap root, 10 to 20 grams of whiteflowerhogfenneL root, 10 to 20 grams of cortex magnoliaeofficinalis and 10 to 20 grams of ovientvine. The traditional Chinese medicine is mainly used for treating excessive phlegm and asthma, chest distress, unwell expectoration or chronic cough, and has the characteristics of low cost, simple preparation, no toxic or side effect and obvious curative effect.
By the reference of patent Number CN102319387(A) by HONG LI dated 2011-09-29, titled”Traditional Chinese medicine composition for treating chronic cough”.The invention relates to a traditional Chinese medicine composition for treating chronic cough, which is characterized in that the composition comprises the following raw material herbs by weight: 20-30 parts of pyrrosia lingua, 18-22 parts of Chinese yam, 12-18 parts of salvia, 10-15 parts of radix stemonae, 8-12 parts of tussilago, 25-35 parts of serissaserissoide, 12-18 parts of eucommiaulmoides, 12-18 parts of Indian buead, 12-18 parts of adenophoratetraphylla, 2-8 parts of mints, 18-22 parts of radix astragali, 12-18 parts of cornusofficinalis, 12-18 parts of mulberry leaves, 12-18 parts of radix ophiopogonis, 8-12 parts of almonds. The invention has the efficacy of nourishing yin and tonifying qi, moistening lung and relieving cough, has good curative effect, high cure rate, andless side effect, is refreshing, has the treatment purpose of recovering human physiological functions, and has a total effective rate of 93.5%.
By thereference of patent Number CN105767653 (A) by HARBIN TIANYI ECOLOGICAL AGRICULTURAL & SIDELINE PRODUCTS CO LTD dated 2014-12-23, titled “Phlegm-dispersing and cough-relieving willow-leaf spiraea herb and root glutinous rice balls and production method thereof”. The invention discloses phlegm-dispersing and cough-relieving willow-leaf spiraea herb and root glutinous rice balls and a production method thereof. The phlegm-dispersing and cough-relieving willow-leaf spiraea herb and root glutinous rice balls comprise glutinous rice ball wraps and stuffing; and the glutinous rice ball wraps are made of black glutinous rice flour, purple sweet potato flour, oat flour, willow-leaf spiraea herbs and roots, Salvia officinalis,fomesoficinalissporophore, white-back helwingia leaves, Balanophoradioica, Schizomussaendadehiscens roots, pedunculateacronychia leaves, ramie flowers, celosia seeds and Lantana camara leaves. The production method comprises the following main steps: preparing the black glutinous rice flour, preparing a mixed extract, preparing dough, coating the stuffing by the wraps, freezing, and obtaining final products. Tastes of the wraps of the glutinous rice balls disclosed by the invention are effectively improved when compared with traditional wraps which are only made of glutinous rice and water; moreover, values of the wraps are increased, so that the glutinous rice balls disclosed by the invention have the functions of dispersing phlegm, relieving cough, guiding Qi downward, preventing asthma, regulating Qi and relieving pain.
By the reference of patent Number CN110302128(A) by YELLOW RIVER CONSERVANCY TECHNICAL Instated2019-08-20, titled “Whitening and anti-allergy relieving sleep mask rich in natural product extract and preparation method of whitening and anti-allergy relieving sleep mask”.The invention relates to the field of cosmetics, in particular to a whitening and anti-allergy relieving sleep mask rich in natural product extract and a preparation method of the whitening and anti-allergy relieving sleep mask. The mask is prepared by, by weight percentage, 0.5-1% of rice bran extract, 0.5-1% of radix astragali extract, 0.5-2% of Citrus aurantium flower extract, 1-5% of radix sophoraeflavescentis extract, 0.2-1% of semen aesculi extract, 5-10% of tea leaf extract, 0.2-1% of Angelica decursiva extract, 0.2-1% of ginkgo leaf extract, 0.5-1% of sage extract, 0.1-2% of Angelicasinensis root extract, 0.1-2% of notoginseng root extract, 5-10 parts of lipid, 2-8% of emulsifier, 5-30% of moisturizing agent, 0.5-2% of preservatives, 1-3% of thickening agent and the balance deionized water. The mask can fade epidermis pigment and inhibit melanin formation and has effects of whitening, removing freckles and resisting allergy.
By the reference of patent Number BG933 (U1)by SOFARMA AD [BG] dated 2006-12-14titled“ANTITUSSIVE PREPARATION”.The invention relates to antitussive preparation based on plant extracts for medical treatment or assisting the convalescent process in cases of upper respiratory tract inflammation, as well as the post-illness recovery period. It contains a dose of 5 g dry extract of medicinal marshmallow roots (Altheaeofficinalis) 0,09 to 0,11 g; dry extract of thyme (Thymus vulgaris) 0,0035 to 0,00165 g; sodium benzoate 0,0162 to 0,0198 g. The preparation is in the form of water-soluble powder with auxiliary substances: beta-carotene 0,0045 to 0,0055 g; fragrant agent 0,09 to 0,11 g; dextrose 3,44 to 4,2 g; aspartame 0,045 to 0,055 g; citric acid 0,45 to 0,55 g; sodium hydrogen carbonate 0,36 to 0,44 g. It has softening, anti-inflammatory, spasmodic and expectorant action, eases the cough reflex, and leads to general tranquillization of the inflamed organs. The thymol contained in the preparation has certain antibacterial (mainly against cocci bacteria) and antimycotic effect. The sodium benzoate serves as a conservant, and has at the same time expectorant and slight antiseptic action. The powdered preparation is used to make a drink with very good organoleptic properties.
By the reference of patent Number CH699749 (A2)by ANCORA MONICA [CH]dated 2008-10-20titled “Pharmaceutical forms of a mixture of spagyric plants in mother tincture for the treatment of dry cough in children”.Pharmaceutical forms comprise Witepsol H-15 (RTM: suppository base) and a spagyric mother-tincture of the plants Droserarotundifolia, Ephedra, Hydrastiscanadensis, Thymus vulgaris, Amygdala amara, propolis, Catharanthusrosea, Bryoniaalba, Sambucusnigra and Mandragoraofficinalis. The plant components can be in a dissolved, dispersed or suspended form in cocoa butter or similar substance. The dosage forms use semi-synthetic lipophilic excipients either in mixtures or singularly combined with other excipients, water-soluble lipophilic excipients with polyethylene glycols either in a form of different proportions of water-soluble excipients or using a single type of excipient, and lipophilic excipients of glyco-gelatin and glyco-stearates either in mixtures with other excipients or singularly. Water-dispersible excipients are used with or without the presence of non-ionic surfactants for forming oil-in-water emulsions. The excipients accelerate the disaggregation of the pharmaceutical form in the rectum and promote absorption of less soluble actives. Excipients used include e.g. polyoxyethylenesorbitanmonostearate, sorbitan esters of fatty acids and polyoxyethylene esters of fatty acids. All the forms can use excipients in combination with consistency regulators, crystallization initiators, dispersants, absorption promoters and protectants.
By thereference of patent Number by WO/2011/048221dated 28.04.2011titled “ANTI-INFLAMMATORY AGENT CONTAINING HYDROLYSATES OF PLANT EXTRACTS”.The invention relates to an anti-inflammatory agent containing at least one plant hydrolysate, in particular selected from the group Althaeae radix (marshmallow root), Angelica(e) dahurica (Siberian angelica), Angelica(e) sinensis (Chinese angelica), Armoraciarusticana (horseradish), Artemisia scoparia (red stem wormwood), Astragalusmembranaceus (var. Mongolicus) (tragasanth root), Capsicum sp., Capsicum annuum (paprika), Centauriumerythraea (common centaury), Cistusincanus (rock rose), Echinacea angustifolia (coneflower), Echinacea purpurea (coneflower), Equisetiherba (horse tail), Galphimiaglauca, Gentianalutea L. (yellow gentian), Guaiacum officinalis, Hederae folium, Hederahelicis (ivy), Juglandis folium (walnut leaves), Leonurusjaponicus (Chinese motherwort), Levisticum radix, Levisticumofficinalis (lovage), Matricariaeflos (or Floschamomillae (camomile flowers)), Meliatoosendan (Chinaberry fruit), Millefoliiherba (yarrow), Oleaeuropaea (olive), Pelargonium sp. (pelagornia), Phytolaccaamericana (pokeweed), Primulaeflos, Primulae radix, Primulaveris L. (primrose flower), Quercus cortex (oak bark), Rosmarinusofficinalis (rosemary), Rumicisherba (sorrel herb), Salix sp. (willow), Salvia miltiorrhiza (red sage), Sambucusnigra L. (black elderberry), Saposhnikoviadivaricata (Siler), Scutellariabaicalensis (Baikal scullcap), Siegesbeckiapubescens (siegesbeckia herb), Taraxaciherba (dandelion herb), Thymus L. (thyme), Verbena officinalis L. (vervain), Vitexagnuscastus (monk's pepper), Vitisvinifera (wine grapes).
Improved cough and cold syrup formulation and composition process iswithout the following carcinogenic ingredients which having several disadvantages: -
EDTA:-It has been shown to enhance the dermal penetration of other ingredients contained in a product. Thus, cosmetic formulators must exercise caution when combining it with other ingredients potentially harmful if absorbed by the skin. Furthermore, some studies suggest that disodium EDTA is weakly mutagenic (probably due to the fact that it binds with metals required for healthy cell division.). The other point is that EDTA builds upcomplexes in the environment that are not biologically degradable.
Parabens (preservative):-The Cosmetics, Toiletries and Perfumery Association released a statement in response to the bad press parabens were receiving after a study by P.D. Darbre was published that suggested paraben usage could be connected to breast cancer. They declared: “Parabens are officially approved for use under the Cosmetics Directive (76/768/EEC), the European legislation that regulates all cosmetics and toiletries. We can reassure the public that all cosmetic and toiletry products containing parabens may continue to be used safely.” Despite this, many people still have doubts and the parabens get a very bad press. The claim “paraben free” becomes a real USP on the market. The EU Commission banned the use of five other parabens in cosmetic products - Isopropylparaben, Isobutylparaben, Phenylparaben, Benzylparaben and Pentylparaben (See Commission Regulation (EU) No 358/2014) due to the lack of data necessary for reassessment. Products placed on the market after 30 October 2014 will have to befree from these substances.
Steriod : Steroid use is associated with several adverse effects, such as an increased risk of heart disease and liver toxicity and there is an increased risk of contamination and infection. Steroid use may cause infertility and baldness in men. Deepening voice, facial changes and hair growth, enlarged clitoris, irregular menstrual cycles, decreased breast size and infertility in women.
No added flavour
However, none of the above discussed inventions provides improvedcough and cold syrup formulation and composition process containsSalviaofficinalis leaf extract, Cetrariaislandica extract and Thyme fluid extract.All the above discussed inventions are not providing such improved cough and cold syrup formulation which fight inflammation in the mouth and throat and contribute to the relief and help to body to eliminate accumulated mucus.
Objects of the invention:
The main object of the present invention is to provide animproved cough and cold syrup composition and formulation process containing Salviaofficinalis leaf extract, Cetrariaislandica extract, Thyme fluid extract.
Another object of the present invention is to provideanimproved cough and cold syrup composition and formulation process containing Salvia officinalis leaf extract having antibacterial effect that helps fight inflammation in the mouth and throat.
Another object of the present invention is to provideanimproved cough and cold syrup composition and formulation process containing Cetrariaislandica extract that is used in irritation of the mucous membrane in the mouth and throat and contributes to the relief.
Another object of the present invention is to provideanimproved cough and cold syrup composition and formulation process containing Thyme fluid extract which is the first rate expectorant, adding the body to eliminate accumulated mucus.
Another object of the present invention is to provide an improved cough and cold syrup having combination of herbs that helps sooth the throat to ease coughing and promote restful sleep.
Another object of the present invention is to provide an improved cough and cold syrup that helps “expel” the mucous by loosening it up and making it easier to cough up.
Summary of the invention:
The present invention provides an improved cough and cold syrup composition and formulation process containing Salvia officinalis leaf extract, Cetrariaislandica extract, Thyme fluid extract;Menthol; Purified water; Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerin.Improved cough and cold syrup compositionfight inflammation in the mouth and throat; also used inirritation of the mucous membrane in the mouth and throat and contributes to the relief; helps to body to eliminate accumulated mucus. The Improved cough and cold syrup formulation and composition process comprises steps of: boiling purified water at 100ºC and cooling till 70ºC; adding all the components Potassium Sorbate in the range of 0.01 to 0.36, Sodium Benzoate in the range of 0.02 to 0.38, Trehalose in the range of 0.1 to 5.2, Mannitol in the range of 0.1 to 6.4, Sorbitol 70% in the range of 1 to 15, Xanthan Gumin the range of 0.05 to 0.8, Sodium Saccharin 0.01 to 1.1, Glycerine in the range of 0.4 to 15; one after the other under stirring; homogenizing the mixture for 10 minutes; adding the components Sage Leaf extract in range of 1.00 to 9.00, Lichen/Chharilla extract in the range of 0.8 to 8.12, Thyme fluid Extract in the range of 1.11 to 11.23, Menthol in the range of 0.001 to 1.1 under stirring condition and homogenizing and finally checking the pH and adjusting between 5.5-6.0 with the help of citric acid solution to obtain the final formulation.
Statement of the invention:
Accordingly, the present invention provides an improved, completely herbal and Steriod-free cough and cold formulation and a process of preparing thereof, said formulation exhibiting an antibacterial effect that helps fight inflammation in the mouth and throat, said formulation comprising Salvia officinalis leaf extract, Cetrariaislandica extract and Thyme fluids extract as active ingredients, said formulation effective against irritation of the mucous membrane in the mouth and throat, characterized in that said formulation enables to expel the mucous by loosening it up and making it easier to cough up, thus providing support to the body in fighting the infection resulting in soothing the throat to ease coughing and promoting restful sleep.
Detaileddescription of invention:
The present invention has been described herein after with reference to the accompanying tables, in which some, but not all embodiments of the invention are shown. While the following description details the preferred embodiments of the present invention is not limited in its application to the details of composition and formulation process. With reference to the embodiments, the enclosed description merely illustrative of preferred embodiments and represent several different ways of configuring the present invention. Although specific components, materials, configurations and uses of the present invention are illustrated and set forth in this disclosure, it should be understood that a number of variations to the components described herein and in the accompanying formulations can be made without changing the scope and function of the invention set forth herein.
The present invention provides an improved cough and cold syrup composition and formulation process containing Salvia officinalis leaf extract having an antibacterial effect that helps fight inflammation in the mouth and throat;Cetrariaislandica extract is used in irritation of the mucous membrane in the mouth and throat and contributes to the relief; Thyme fluids extractwhich is the first rate expectorant, adding the body to eliminate accumulated mucus; Sage Leaf extract; Lichen/Chharilla extract; Thyme fluid Extract; Menthol; Purified water; Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerin.Since preferenceis given to support the body in fighting the infection rather than take something that bypasses this natural process. So the combination of herbs in the present invention helps sooth the throat to ease coughing and promote restful sleep. It helps “expel” the mucous by loosening it up and making it easier to cough up.
The improved cough and cold syrup formulation and composition process comprises following steps:
Step 1:Boil purified water at 100ºC and cool till 70ºC; and add all the components Potassium Sorbate in the range of 0.01 to 0.36, Sodium Benzoate in the range of 0.02 to 0.38, Trehalose in the range of 0.1 to 5.2, Mannitol in the range of 0.1 to 6.4, Sorbitol 70% in the range of 1 to 15, Xanthan Gum in the range of 0.05 to 0.8, Sodium Saccharin 0.01 to 1.1, Glycerine in the range of 0.4 to 15; one after the other under stirring.
Step 2:homogenizing the mixture for 10 minutes.
Step 3:Addthe components Sage Leaf extract in range of 1.00 to 9.00, Lichen/Chharilla extract in the range of 0.8 to 8.12, Thyme fluid Extract in the range of 1.11 to 11.23, Menthol in the range of 0.001 to 1.1 under stirring condition and homogenizing and.
Step 4:Finally checking the pH and adjusting between 5.5-6.0 with the help of citric acid solution to obtain the final formulation.
The present invention comprising means Sage Leaf extrac (Salvia officinalis)from Qty. in % 1.00 to Qty. in % 9.00 and exact amount of Qty. in % 6.0.
The present invention comprising means Lichen/Chharilla extract(Cetrariaislandica) from Qty. in % 1.00 to Qty. in % 9.00 and exact amount of Qty. in % 6.0.
The present invention comprising means Thyme fluid Extract (Thymus vulgaris)from Qty. in %1.11 to Qty. in % 11.23 and exact amount of Qty. in % 8.0.
The present invention comprising means Mentholfrom Qty. in % 0.001 to Qty. in % 1.1 and exact amount of Qty. in % 0.05.
The present invention comprising means Purified water from Qty. in % QS to Qty. in % QS and exact amount of Qty. in % QS.
The present invention comprising means Potassium Sorbate from Qty. in % 0.01 to Qty. in % 0.36 and exact amount of Qty. in % 0.15.
The present invention comprising means Sodium Benzoatefrom Qty. in % 0.02 to Qty. in % 0.38 and exact amount of Qty. in % 0.15.
The present invention comprising means Trehalose from Qty. in % 0.1 to Qty. in % 5.2 and exact amount of Qty. in % 1.0.
The present invention comprising means Mannitol from Qty. in % 0.1 to Qty. in % -6.4 and exact amount of Qty. in % 1.0.
The present invention comprising means Sorbitol 70% from Qty. in % 1 to Qty. in % 15 and exact amount of Qty. in % 5.0.
The present invention comprising means Xanthan Gum from Qty. in % 0.05 to Qty. in % 0.8 and exact amount of Qty. in % 0.25.
The present invention comprising means Sodium Saccharin from Qty. in % 0.01 to Qty. in % 1.1 and exact amount of Qty. in % 0.1.
The present invention comprising means Glycerin from Qty. in % 0.4 to Qty. in % -15 and exact amount of Qty. in % 5.0.
Table 1: Represents ingredients in the range in terms of percentage:
S.No. Ingredients
Botanical Name From to
Qty. in % Qty. in %
1 Sage Leaf extract Salvia officinalis 1.00 9.00
2 Lichen/Chharilla extract Cetrariaislandica 0.80 8.12
3 Thyme fluid Extract Thymus vulgaris 1.11 11.23
4 Menthol 0.001 1.1
5 Purified water QS QS
6 Potassium Sorbate 0.01 0.36
7 Sodium Benzoate 0.02 0.38
8 Trehalose 0.1 5.2
9 Mannitol 0.1 6.4
10 Sorbitol 70% 1 15
11 Xanthan Gum 0.05 0.8
12 Sodium Saccharin 0.01 1.1
13 Glycerin 0.4 15

So the present invention provides an improved cough and cold formulation and a process of preparing thereof, said formulation exhibiting an antibacterial effect that helps fight inflammation in the mouth and throat, said formulation comprising Salvia officinalis leaf extract, Cetrariaislandica extract and Thyme fluids extract as active ingredients, said formulation effective against irritation of the mucous membrane in the mouth and throat, characterized in that said formulation enables to expel the mucous by loosening it up and making it easier to cough up, thus providing support to the body in fighting the infection resulting in soothing the throat to ease coughing and promoting restful sleep.
In an embodiment, said formulation is preferably in the form of syrup.
In another embodiment, said formulation is preferably in the form of a tablet.

In embodiment, the present invention provides Improved improved cough and cold syrup composition and formulation,containing Salvia officinalis leaf extract, Cetrariaislandica extract, Thyme fluid extract, Menthol,purified water; Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerin.
In another embodiment, the present invention provides Improved cough and cold syrup composition.The combination of herbs that helps sooth the throat to ease coughing and promote restful sleep. It helps “expel” the mucous by loosening it up and making it easier to cough up.
In another embodiment, the present invention provides improved cough and cold syrup composition whereinSalvia officinalis leaf Extract has an antibacterial effect that helps fight inflammation in the mouth and throat. Cetrariaislandica Extract is used in irritation of the mucous membrane in the mouth and throat and contributes to the relief. Thyme fluid extract is the first rate expectorant, adding the body to eliminate accumulated mucus.
In another embodiment, the present invention providesimproved cough and cold syrup formulation and a process for making the formulation, comprises the step 1 of: Boil purified water at 100ºC and cool till 70ºC; and add all the components Potassium Sorbate in the range of 0.01 to 0.36, Sodium Benzoate in the range of 0.02 to 0.38, Trehalose in the range of 0.1 to 5.2, Mannitol in the range of 0.1 to 6.4, Sorbitol 70% in the range of 1 to 15, Xanthan Gumin the range of 0.05 to 0.8, Sodium Saccharin 0.01 to 1.1, Glycerine in the range of 0.4 to 15; one after the other under stirring.
In another embodiment, the present invention providesimproved cough and cold syrup formulation and a process for making the formulation, comprises the step2of: homogenizing the mixture for 10 minutes.
In another embodiment, the present invention providesimproved cough and cold syrup formulation and a process for making the formulation, comprises the step3of: Addthe components Sage Leaf extract in range of 1.00 to 9.00, Lichen/Chharilla extract in the range of 0.8 to 8.12, Thyme fluid Extract in the range of 1.11 to 11.23, Menthol in the range of 0.001 to 1.1 under stirring condition and homogenizing and.
In another embodiment, the present invention providesimproved cough and cold syrup formulation and a process for making the formulation, comprises the step 4 of: Finally checking the pH and adjusting between 5.5-6.0 with the help of citric acid solution to obtain the final formulation.
In another embodiment, the present invention providesSage Leaf extrac (Salvia officinalis) from Qty. in % 1.00 to Qty. in % 9.00 and exact amount of Qty. in % 6.0.
In another embodiment, the present invention providesLichen/Chharilla extract(Cetrariaislandica) from Qty. in % 1.00 to Qty. in % 9.00 and exact amount of Qty. in % 6.0.
In another embodiment, the present invention providesThyme fluid Extract (Thymus vulgaris) from Qty. in %1.11 to Qty. in % 11.23 and exact amount of Qty. in % 8.0.
In another embodiment, the present invention providesMentholfrom Qty. in % 0.001 to Qty. in % 1.1 and exact amount of Qty. in % 0.05.
In another embodiment, the present invention providesPurified water from Qty. in % QS to Qty. in % QS and exact amount of Qty. in % QS.
In another embodiment, the present invention providesPotassium Sorbate from Qty. in % 0.01 to Qty. in % 0.36 and exact amount of Qty. in % 0.15.
In another embodiment, the present invention providesSodium Benzoatefrom Qty. in % 0.02 to Qty. in % 0.38 and exact amount of Qty. in % 0.15.
In another embodiment, the present invention providesTrehalose from Qty. in % 0.1 to Qty. in % 5.2 and exact amount of Qty. in % 1.0.
In another embodiment, the present invention providesMannitol from Qty. in % 0.1 to Qty. in % -6.4 and exact amount of Qty. in % 1.0.
In another embodiment, the present invention providesSorbitol 70% from Qty. in % 1 to Qty. in % 15 and exact amount of Qty. in % 5.0.
In another embodiment, the present invention providesXanthan Gum from Qty. in % 0.05 to Qty. in % 0.8 and exact amount of Qty. in % 0.25.
In another embodiment, the present invention providesSodium Saccharin from Qty. in % 0.01 to Qty. in % 1.1 and exact amount of Qty. in % 0.1.
In another embodiment, the present invention providesGlycerin from Qty. in % 0.4 to Qty. in % -15 and exact amount of Qty. in % 5.0.

Advantages:
I) The invention provides Bronchitis Syrup.
II) The improved syrup helps sooth the throat to ease coughing and promote restful sleep and “expel” the mucous by loosening it up and making it easier to cough up.
III) It provides antibacterial effect that helps fight inflammation in the mouth and throat.
IV) It helps body to eliminate accumulated mucus.
Table 2: Represents exact amount of the ingredients in terms of percentage usedin the lab during experimentations:
S.No. Ingredients Botanical Name Qty. in %
1 Sage Leaf extract Salvia officinalis 6.0
2 Lichen/Chharilla extract Cetrariaislandica 5.0
3 Thyme fluid Extract Thymus vulgaris 8.0
4 Menthol 0.05
5 Purified water QS
6 Potassium Sorbate 0.15
7 Sodium Benzoate 0.15
8 Trehalose 1.0
9 Mannitol 1.0
10 Sorbitol 70% 5.0
11 Xanthan Gum 0.25
12 Sodium Saccharin 0.1
13 Glycerin 5.0

Claims:We claim:
1. An improved, completely herbal and Steriod-free cough and cold formulation and a process of preparing thereof, said formulation exhibiting an antibacterial effect that helps fight inflammation in the mouth and throat,said formulation comprising Salvia officinalis leaf extract, Cetrariaislandica extract and Thyme fluids extract as active ingredients, said formulation effective against irritation of the mucous membrane in the mouth and throat, characterized in that said formulation enables to expel the mucous by loosening it up and making it easier to cough up, thus providing support to the body in fighting the infection resulting in soothing the throat to ease coughing and promoting restful sleep.
2. The improved, completely herbal and chemical-free cough and cold syrup formulation as claimed in claim 1, wherein said formulation is preferably in the form of syrup.
3. The improved, completely herbal and chemical-free cough and cold syrup formulation as claimed in claim 1, wherein said formulation is preferably in the form of a tablet.
4. The improved, completely herbal and chemical-freecough and cold syrup formulation as claimed in claim 1, wherein said Cetrariaislandica extract is effective against irritation of the mucous membrane in the mouth and throat and contributes to the relief.
5. The improved, completely herbal and chemical-freecough and cold syrup formulation as claimed in claim 1, wherein said Thyme fluids extractworks as an expectorant, helping to eliminate accumulated mucus.
6. The improved, completely herbal and steriod-freecough and cold syrup formulation as claimed in claim 1, wherein saidSalvia officinalis (Sage Leaf extract) is in the range of 1 to 9 percent, Cetrariaislandica (Lichen/Chharilla extract) is in the range of 0.8 to 8.12 percent; Thymus vulgaris (Thyme fluid Extract) is in the range of 1.11 to 11.23 percent; Menthol 0.001 to 1.1 percent, potassium sorbate 0.01 to 0.36 percent; sodium benzoate 0.02 to 0.38 percent; Trehalose 0.1 to 5.2 percent; Mannitol 0.1 to 6.4 percent; Sorbitol 70 from 1 to 15 percent; Xanthan Gum from 0.05 to 0.8 percent; Sodium Saccharin from 0.01 to 1.1 percent and Glycerin from 0.4 to 15 percent.
7. The improved, completely herbal and steriod-free cough and cold syrup formulation as claimed in claim 1, wherein said process for making the formulation, comprises the steps of: boiling purified water at 100ºC and cooling till 70ºC; adding all the components Potassium Sorbate in the range of 0.01 to 0.36, Sodium Benzoate in the range of 0.02 to 0.38, Trehalose in the range of 0.1 to 5.2, Mannitol in the range of 0.1 to 6.4, Sorbitol 70% in the range of 1 to 15, Xanthan Gumin the range of 0.05 to 0.8, Sodium Saccharin 0.01 to 1.1, Glycerine in the range of 0.4 to 15; one after the other under stirring; homogenizing the mixture for 10 minutes; adding the components Sage Leaf extract in range of 1.00 to 9.00, Lichen/Chharilla extract in the range of 0.8 to 8.12, Thyme fluid Extract in the range of 1.11 to 11.23, Menthol in the range of 0.001 to 1.1 under stirring condition and homogenizing and finally checking the pH and adjusting between 5.5-6.0 with the help of citric acid solution to obtain the final formulation.

Documents

Application Documents

# Name Date
1 202011046609-STATEMENT OF UNDERTAKING (FORM 3) [26-10-2020(online)].pdf 2020-10-26
2 202011046609-FORM 1 [26-10-2020(online)].pdf 2020-10-26
3 202011046609-DECLARATION OF INVENTORSHIP (FORM 5) [26-10-2020(online)].pdf 2020-10-26
4 202011046609-COMPLETE SPECIFICATION [26-10-2020(online)].pdf 2020-10-26
5 202011046609-Proof of Right [06-11-2020(online)].pdf 2020-11-06
6 202011046609-FORM-26 [06-11-2020(online)].pdf 2020-11-06
7 202011046609-Power of Attorney-091120.pdf 2021-10-19
8 202011046609-OTHERS-091120.pdf 2021-10-19
9 202011046609-FORM 18 [20-09-2023(online)].pdf 2023-09-20
10 202011046609-Verified English translation [10-01-2025(online)].pdf 2025-01-10
11 202011046609-Verified English translation [10-04-2025(online)].pdf 2025-04-10
12 202011046609-Verified English translation [20-06-2025(online)].pdf 2025-06-20