"An Improved Process For The Preparation Of 1 [[N Methyl N 3

"An Improved Process For The Preparation Of 1 [[N Methyl N 3 [(Methylamino)acetoxymethyl] Pyridin 2 Yl] Carbamoyloxy] Ethyl 1 [(2 R,3 R) 2 (2,5 Difluorophenyl) 2 Hydroxy 3 [4 (4 Cyanophenyl) Thiazol 2 Yl] Butyl] 1 H [1,2,4] Triazo 4 Iumsulfate"

Abstract: ABSTRACT "AN IMPROVED PROCESS FOR THE PREPARATION OF 1-[[N-METHYL-N-3-[(METHYLAMINO)ACETOXYMETHYL] PYRIDIN-2-YL] CARBAMOYLOXY] ETHYL- 1-[(2R,3R)-2-(2,5-DIFLUOROPHENYL)-2-HYDROXY-3-[4-(4-CYANOPHENYL) THIAZOL-2-YL] BUTYL]-1H- [1,2,4]-TRIAZO-4-IUMSULFATE" The present invention relates to an improved process for the preparation of 1-[[N-methyl-N-3-[(methylamino)acetoxymethyl] pyridin-2-yl] carbamoyloxy] ethyl- 1-[(2R,3R)-2-(2,5-difluorophenyl)-2-hydroxy-3-[4-(4-cyanophenyl) thiazol-2-yl] butyl]-1H- [1,2,4]-triazo-4-iumsulfate (1) having purity greater than 99.5 % by High-performance liquid chromatography (HPLC).

Patent Information

Application #

Filing Date

17 October 2022

Publication Number

16/2024

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

Parent Application