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An Improved Process For The Preparation Of 6 O Methyl Erythromycin A Derivative

Abstract: The present invention relates to an improved process for the preparation of 6-0-methylerythromycin A derivatives, intermediates of clarithromycin, by selective methylation of erythromycin A derivative in a mixture of a acyclic or cyclic alkanes having C6-C10 carbon atoms, and a polar aprotic solvent using a methylating agent in the presence of a bsed under mild conditions.

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Patent Information

Application #
Filing Date
23 March 2005
Publication Number
34/2007
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

IND-SWIFT LABORATORIES LIMITED,
S.C.O. NO. 850, SHIVALIK ENCLAVE, NAC MANIMAJRA, CHANDIGARH-160101, INDIA.

Inventors

1. CHIDAMBARAM VENKATESWARAN SRINIVASAN,
S.C.O. NO. 850, SHIVALIK ENCLAVE, NAC MANIMAJRA, CHANDIGARH-160101, INDIA.
2. RAHUL SAXENA
IND-SWIFT LABORATORIES LIMITED, S.C.O. NO. 850, SHIVALIK ENCLAVE, NAC MANIMAJRA, CHANDIGARH-160101, INDIA.
3. PRANAV GUPTA
IND-SWIFT LABORATORIES LIMITED, S.C.O. NO. 850, SHIVALIK ENCLAVE, NAC MANIMAJRA, CHANDIGARH-160101, INDIA.

Specification

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