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An Improved Process For The Preparation Of Clobazam
Abstract: The present invention relates to a process for the preparation of Clobazam (I), wherein a compound (Va) is reacted with alkyl malonyl chloride to produce a compound (IVa), which is cyclized to produce N-desmethyl clobazam (IV) followed by N-methylation with methylating agent to obtain Clobazam (I). The present invention is also directed towards a process for the purification of Clobazam (I), wherein a chelating agent is added to clobazam (I) solution dissolved in a solvent, followed by the addition of preservative agent and charcoal, which is then isolated to obtain pure Clobazam (I).
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
07 October 2015
Publication Number
29/2017
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application
Applicants
AUROBINDO PHARMA LTD
THE WATER MARK BUILDING, PLOT NO. 11, SURVEY NO. 9, KONDAPUR , HITECH CITY, HYDERABAD - 500 084,
Inventors
1. DR.T.V.S.K.VITTAL
AUROBINDO PHARMA LTD, THE WATER MARK BUILDING, PLOT NO. 11, SURVEY NO. 9, KONDAPUR , HITECH CITY, HYDERABAD - 500 084,
2. DR.RAMA SHANKAR
AUROBINDO PHARMA LTD, THE WATER MARK BUILDING, PLOT NO. 11, SURVEY NO. 9, KONDAPUR , HITECH CITY, HYDERABAD - 500 084,
3. DR.NAGESHWAR DUSSA
AUROBINDO PHARMA LTD, THE WATER MARK BUILDING, PLOT NO. 11, SURVEY NO. 9, KONDAPUR , HITECH CITY, HYDERABAD - 500 084,
4. MR.KAKI GOWRI SANKAR RAO
AUROBINDO PHARMA LTD, THE WATER MARK BUILDING, PLOT NO. 11, SURVEY NO. 9, KONDAPUR , HITECH CITY, HYDERABAD - 500 084,
5. MR.THUDI PURENDAR REDDY
AUROBINDO PHARMA LTD, THE WATER MARK BUILDING, PLOT NO. 11, SURVEY NO. 9, KONDAPUR , HITECH CITY, HYDERABAD - 500 084,
6. MR.MAHESH PANASA
AUROBINDO PHARMA LTD, THE WATER MARK BUILDING, PLOT NO. 11, SURVEY NO. 9, KONDAPUR , HITECH CITY, HYDERABAD - 500 084,
7. DR.MEENAKSHISUNDERAM SIVAKUMARAN
AUROBINDO PHARMA LTD, THE WATER MARK BUILDING, PLOT NO. 11, SURVEY NO. 9, KONDAPUR , HITECH CITY, HYDERABAD - 500 084,
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 5358-CHE-2015-FORM 3 [24-05-2019(online)].pdf | 2019-05-24 |
| 1 | 5358-CHE-2015-Other Patent Document-071015.pdf | 2015-10-24 |
| 2 | 5358-CHE-2015-Correspondence-231015.pdf | 2016-04-04 |
| 2 | 5358-CHE-2015-Form 2(Title Page)-071015.pdf | 2015-10-24 |
| 3 | 5358-CHE-2015-Form 1-071015.pdf | 2015-10-24 |
| 3 | 5358-CHE-2015-Form 1-231015.pdf | 2016-04-04 |
| 4 | 5358-CHE-2015-OTHERS-231015.pdf | 2016-04-04 |
| 5 | 5358-CHE-2015-Form 1-071015.pdf | 2015-10-24 |
| 5 | 5358-CHE-2015-Form 1-231015.pdf | 2016-04-04 |
| 6 | 5358-CHE-2015-Correspondence-231015.pdf | 2016-04-04 |
| 6 | 5358-CHE-2015-Form 2(Title Page)-071015.pdf | 2015-10-24 |
| 7 | 5358-CHE-2015-FORM 3 [24-05-2019(online)].pdf | 2019-05-24 |
| 7 | 5358-CHE-2015-Other Patent Document-071015.pdf | 2015-10-24 |