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An Improved Process For The Preparation Of Droxidopa And Its Intermediate
Abstract: The present invention provides an improved process for preparation of the L-threo—(2S,3R)—3- ' (3.4-dihydroxyphenyl)serine (I), which is known as Droxidopa; comprising (a) reaction of the aldehyde compound (III) (as described herein)with Metal complex (II) (as described herein), and (b) hydrolysis of the compound (IV) obtained from step (a) in presence of acid. The present invention also relates to a novel intermediates metal chiral complex (IV) for the preparation of Droxidopa.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
30 March 2016
Publication Number
40/2017
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application
Patent Number
Legal Status
Grant Date
2021-11-22
Renewal Date
Applicants
PIRAMAL ENTERPRISES LIMITED
PIRAMAL TOWER, GANPATRAO KADAM MARG, LOWER PAREL, MUMBAI-400 013, STATE OF MAHARASHTRA,INDIA
Inventors
1. GHARPURE, MILIND
LIGHT HALL A WING, HIRANANDANI BUSINESS PARK, SAKI VIHAR ROAD, CHANDIVALI, ANDHERI (EAST), MUMBAI, MAHARASHTRA-400072, INDIA
2. JAGTAP, ASHUTOSH
LIGHT HALL A WING, HIRANANDANI BUSINESS PARK, SAKI VIHAR ROAD, CHANDIVALI, ANDHERI (EAST), MUMBAI, MAHARASHTRA-400072, INDIA
3. RAUT, CHANGDEV
LIGHT HALL A WING, HIRANANDANI BUSINESS PARK, SAKI VIHAR ROAD, CHANDIVALI, ANDHERI (EAST), MUMBAI, MAHARASHTRA-400072, INDIA
4. KANSAGARA, NAINESH
LIGHT HALL A WING, HIRANANDANI BUSINESS PARK, SAKI VIHAR ROAD, CHANDIVALI, ANDHERI (EAST), MUMBAI, MAHARASHTRA-400072, INDIA
5. KRISHNAPILLAI, JAISANKAR
ENNORE EXPRESS HIGHWAY, ERNAVOOR PO, ENNORE, CHENNAI, TAMILNADU-600057, INDIA
6. MANOHARAN, NIRMAL KUMAR
ENNORE EXPRESS HIGHWAY, ERNAVOOR PO, ENNORE, CHENNAI, TAMILNADU-600057, INDIA
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 201621010969-FORM 5-29-03-2017.pdf | 2017-03-29 |
| 2 | 201621010969-FORM 3-29-03-2017.pdf | 2017-03-29 |
| 3 | 201621010969-FORM 2-29-03-2017.pdf | 2017-03-29 |
| 4 | 201621010969-FORM 2(TITLE PAGE)-29-03-2017.pdf | 2017-03-29 |
| 5 | 201621010969-FORM 1-29-03-2017.pdf | 2017-03-29 |
| 6 | 201621010969-DESCRIPTION(COMPLETE)-29-03-2017.pdf | 2017-03-29 |
| 7 | 201621010969-CORRESPONDENCE-29-03-2017.pdf | 2017-03-29 |
| 8 | 201621010969-CLAIMS-29-03-2017.pdf | 2017-03-29 |
| 9 | 201621010969-ABSTRACT-29-03-2017.pdf | 2017-03-29 |
| 10 | 201621010969-CORRESPONDENCE-28-04-2017.pdf | 2017-04-28 |
| 11 | 201621010969-FORM 3 [02-01-2018(online)].pdf | 2018-01-02 |
| 12 | 201621010969-Other Patent Document-300316.pdf | 2018-08-11 |
| 13 | 201621010969-Form 3-300316.pdf | 2018-08-11 |
| 14 | 201621010969-Form 2(Title Page)-300316.pdf | 2018-08-11 |
| 15 | 201621010969-Form 1-300316.pdf | 2018-08-11 |
| 16 | 201621010969-Form 1-220416.pdf | 2018-08-11 |
| 17 | 201621010969-FORM 3 [12-11-2018(online)].pdf | 2018-11-12 |
| 18 | 201621010969-FORM 3 [09-01-2019(online)].pdf | 2019-01-09 |
| 19 | 201621010969-FORM 3 [08-07-2019(online)].pdf | 2019-07-08 |
| 20 | 201621010969-FORM 3 [09-01-2020(online)].pdf | 2020-01-09 |
| 21 | 201621010969-FORM 18 [09-03-2020(online)].pdf | 2020-03-09 |
| 22 | 201621010969-FER.pdf | 2020-06-25 |
| 23 | 201621010969-FORM 3 [09-07-2020(online)].pdf | 2020-07-09 |
| 24 | 201621010969-PA [04-12-2020(online)].pdf | 2020-12-04 |
| 25 | 201621010969-ASSIGNMENT DOCUMENTS [04-12-2020(online)].pdf | 2020-12-04 |
| 26 | 201621010969-8(i)-Substitution-Change Of Applicant - Form 6 [04-12-2020(online)].pdf | 2020-12-04 |
| 27 | 201621010969-OTHERS [24-12-2020(online)].pdf | 2020-12-24 |
| 28 | 201621010969-FER_SER_REPLY [24-12-2020(online)].pdf | 2020-12-24 |
| 29 | 201621010969-FORM 3 [10-01-2021(online)].pdf | 2021-01-10 |
| 30 | 201621010969-FORM 3 [09-07-2021(online)].pdf | 2021-07-09 |
| 31 | 201621010969-FORM 3 [16-07-2021(online)].pdf | 2021-07-16 |
| 32 | 201621010969-POA [19-10-2021(online)].pdf | 2021-10-19 |
| 33 | 201621010969-FORM 13 [19-10-2021(online)].pdf | 2021-10-19 |
| 34 | 201621010969-AMENDED DOCUMENTS [19-10-2021(online)].pdf | 2021-10-19 |
| 35 | 201621010969-PatentCertificate22-11-2021.pdf | 2021-11-22 |
| 36 | 201621010969-IntimationOfGrant22-11-2021.pdf | 2021-11-22 |
| 37 | 201621010969-FORM 5-29-03-2017.pdf | 2017-03-29 |
| 37 | 201621010969-RELEVANT DOCUMENTS [29-09-2023(online)].pdf | 2023-09-29 |
Search Strategy
| 1 | 969searchstrategyE_23-06-2020.pdf |