Abstract: The present invention generally relates to a process for the preparation of plecanatide. Specifically, the present invention relates to an improved process for preparation of plecanatide using a non-linear solid phase peptide synthesis. In particular, the process for preparation of plecanatide of the present invention involves solid phase synthesis of peptide fragments of five amino acid units using 2-chlorotrityl chloride (2-ClTrt) resin and eleven amino acid unit using Wang resin.
| # | Name | Date |
|---|---|---|
| 1 | 202147026429-STATEMENT OF UNDERTAKING (FORM 3) [14-06-2021(online)].pdf | 2021-06-14 |
| 2 | 202147026429-POWER OF AUTHORITY [14-06-2021(online)].pdf | 2021-06-14 |
| 3 | 202147026429-FORM 1 [14-06-2021(online)].pdf | 2021-06-14 |
| 4 | 202147026429-DRAWINGS [14-06-2021(online)].pdf | 2021-06-14 |
| 5 | 202147026429-DECLARATION OF INVENTORSHIP (FORM 5) [14-06-2021(online)].pdf | 2021-06-14 |
| 6 | 202147026429-COMPLETE SPECIFICATION [14-06-2021(online)].pdf | 2021-06-14 |
| 7 | 202147026429.pdf | 2021-10-18 |