AN IMPROVED PRODUCT

FIELD OF THE INVENTION

The present invention in general relates to a composition for correction of defective nervous system and in particular to a composition derived from natural and commonly available products, said composition being effective in treatment of acute neurological diseases such as Parkinson's disease.

BACKGROUND OF THE INVENTION

Neurological diseases are intensifying with the growing mental and physical stress in the highly developing modern society. Parkinson's disease in particular is one of such acute neurological disease.

Parkinson is a well-known disease in art, with no particular medicine available in market to cure it completely. Parkinson's disease is associated with a disorder of nervous system of the body. It hampers the normal activities of the body such as walking, movement, or co-ordination and sometimes speaking. The reason for this disease could be genetic or sometime could be the result of adverse effect of modernization and environmental factor. Multidisciplinary scientific investigations are making best efforts to combat this disease, but the sure-shot; the perfect cure is yet to be deciphered.

Though Parkinson's disease often develops after the age of fifty, but due to the adverse effect of modernization, it could happen at very younger age also. It affects both men and women.

Nerve cells use a brain chemical called dopamine to help control muscle movement. Parkinson's disease occurs when the nerve cells in the brain that make dopamine are slowly destroyed. Without dopamine, the nerve cells in the part of the brain can not properly send messages. This leads to the loss of muscle function. The damage gets worse with time. Although it is well known that lack of dopamine causes the motor symptoms of Parkinson's disease, it is not clear why the dopamine-producing brain cells deteriorate. Genetic and pathological studies have revealed that various dysfunctional cellular processes, inflammation, and stress can all contribute to cell damage.

There is currently no sacrosanct treatment to cure Parkinson's disease. Several therapies are available to delay the onset of motor symptoms and to ameliorate motor symptoms. All of these therapies are designed to increase the amount of dopamine in the brain either by replacing dopamine, mimicking dopamine, or prolonging the effect of dopamine by inhibiting its breakdown. Studies have shown that early therapy in the non-motor stage can delay the onset of motor symptoms, thereby extending quality of life.

In earlier stages of Parkinson's disease, substances that mimic the action of dopamine (dopamine agonists), and substances that reduce the breakdown of dopamine (monoamine oxidase type B (MAO-B) inhibitors) can be used for treatment of Parkinson's disease. For some individuals with advanced, virtually unmanageable stage, surgery may be the only option.

It is known that effective therapy for Parkinson's disease can be levodopa (Sinemet), which is converted to dopamine in the brain. However, long-term treatment with levodopa leads to unpleasant side effects such as a shortened response to each dose, painful cramps, and involuntary movements and so on. In brief, the in vogue therapeutic applications are known to have severe side effects apart from being exorbitantly costly, thereby leading to immense pubic dissatisfaction.

Recently, a greater emphasis has been given towards the researches on complementary and alternative therapies that deal with Parkinson's disease. Several studies have been conducted on herbs for their therapeutic properties. Ayurveda, a traditional Indian treatment has been successfully used from very early times for preventing or suppressing various neurological diseases.

In brief, various natural products or the very commonly available products have been reported through scientific research to possess some therapeutic properties for treatment of Parkinson's disease. However, obtaining a synergistic composition from natural and commonly available products for treatment of acute neurological diseases such as Parkinson's disease in sacrosanct manner is yet to be achieved.

Accordingly, there is a long felt need to obtain a synergistic composition comprising optimum portions of ingredients derived from natural and commonly available products which can be effectively applied for treatment of acute neurological diseases such as Parkinson's disease.

The present invention meets the aforesaid long felt need.
All through out the specification including the claims, the words "ayurvedic", "natural products", "extract", "tablets", "powder", "Parkinson", "neurological disease" are to be interpreted in the broadest sense of the respective terms and includes all similar items in the field known by other terms, as may be clear to persons skilled in the art. Restriction/limitation, if any, referred to in the specification, is solely by way of example and understanding the present invention.

Furthermore, the present invention has been described with reference to "Parkinson's disease" for the sake of understanding only. It should be understood that the present invention is effectively applicable for treatment of other neurological diseases as well.

OBJECTS OF THE INVENTION

It is the principal object of the present invention to provide a synergistic composition derived from natural and commonly available products, for treatment of acute neurological diseases such as Parkinson's disease.

It is another object of the present invention to provide a synergistic composition, that rejuvenates the brain activity and strengthens the nerves in human beings suffering from Parkinson's disease.
It is further object of the present invention to provide a synergistic composition that increases the fresh blood circulation, thereby maintaining the proper blood temperature of patients suffering from Parkinson's disease.

It is yet another object of the present invention to provide a synergistic composition for effective correction of Parkinson's disease in patients, which on application, does not reveal any side effect.

It is a further object of the present invention to provide a synergistic composition, which is available at reasonable cost, in acceptable dosage forms.

It is a further object of the present invention to provide proper treatment to patients suffering from Parkinson's disease for effective correction of brain activity within their body from an optimum combination comprising natural and commonly available products with or without suitable excipients, said combination being adapted to be delivered in acceptable dosage forms.

How the foregoing objects are achieved and the other aspects of the present invention will be clear from the following description, which is purely by way of understanding and not by way of any sort of limitation.

SUMMARY OF THE INVENTION

Accordingly, the present invention provides a composition for treatment of acute neurological diseases such as Parkinson's disease including optimally effective proportions of suitable ingredients, with or without effective proportions of suitable excipient(s), said ingredients including:
i) Mercuric oxide
ii) Soda Carbonate
iii) Raw salt
In accordance with preferred embodiments of the composition of the present invention:
-said ingredients further include:
i) Honey
ii) Curcuma longa
iii) Black Salt
iv) Alahgiumdecapetalum -said Alahgiumdecapetalum serve as extracting media and said honey acts as a sweetening agent;
-said ingredients are applied in dry powder and/or extract form;

In accordance with preferred embodiments of the composition of the present invention:
-said ingredients are applied as follows:
i) Mercuric oxide - 0.316%
ii) Soda Carbonate -0.316%
iii) Honey -95.08%
iv) Curcuma longa -1.58%
v) Alahgiumdecapetalum -1.58%
vi) Raw salt -0.47%
vii) Black Salt -0.62%

The present invention also provide a method for preparation of a composition for correction of defective nervous system, wherein said composition includes optimally effective proportions of suitable ingredients, said ingredients including:

1) Mercuric oxide
2) Soda Carbonate
3) Curcuma longa
4) Alahgiumdecapetalum
5) Raw salt
6) Black Salt

wherein said method includes grinding of Mercuric oxide, Soda Carbonate, Curcuma longa, Raw salt and Black Salt for a suitable duration in Alahgiumdecapetalum extract and drying the same, putting the mixture so obtained in a small closed container and burning with buffalo stool so as form a powder for its application.

In accordance with preferred embodiments of the method of the present invention:
-said powder so obtained is mixed with good proportion of honey;
-pure ghee and/or butter are added as medium.

DETAILED DESCRIPTION OF THE INVENTION

The following describes some preferred embodiments and examples of the present invention, which are purely for the sake of understanding the performance of the invention, and not by way of any sort of limitation.

As stated under the heading "BACKGROUND OF THE INVENTION" the conventional drugs for treatment of Parkinson's disease have been the cause of immense public dissatisfaction due to the severe side effects and involvement of high cost. Furthermore, although, various chemical entities have been reported through scientific research for treatment of Parkinson's disease, a synergistic composition comprising of optimum proportions of ingredients derived from various natural and commonly available products in combination with or without suitable excipients, to provide sacrosanct treatment of defective nervous system in humans suffering from acute neurological diseases such as Parkinson's disease, was very much lacking. The composition according to the present invention is immaculately effective in treatment of Parkinson's disease, is reasonably cheap and has no side effects. This is exactly what the present invention provides.

The present invention is based on the results deciphered through extensive research and the conclusion therefrom, that various nervous disorder and lacking of movement of different parts of the body can be corrected by a synergistic composition derived from various natural and commonly available products, of course in combination with or without other excipients in acceptable dosage. In the above context it is hereby clarified, that simply by way of example and for understanding the present invention and not by way of any limitation, the composition, in accordance with the present invention, have been referred to as being administered to patients in powdered dosage form. It should be understood to persons skilled in the art that the present invention is equally administrable in all other dosage forms such as but not limited to tablets and capsules and will be equally effective on being administered in such dosage forms, in achieving the objects of the present invention.

The present invention provides a composition for treatment of patients suffering from nervous disorder, derived from effective proportions of suitable ingredients with or without effective proportions of suitable excipients(s) said ingredients including:

1) Mercuric oxide (lg)
2) Soda Carbonate (lg)
3) Honey (50g)
4) Curcuma longa (5g)
5) Alahgiumdecapetalum (5g)
6) Raw salt (1.5g)
7) Black Salt (2g)

Here Alahgiumdecapetalum act as an extracting agent and large quantity of honey is mixed to give a sweet taste. Pure ghee or butter can also be used as medium. The ingredients are applied in powdered and/or extract form.

The exemplary proportions by weight in which the ingredients are applied are as follows:

i) Mercuric oxide - 0.316%
ii) Soda Carbonate -0.316%
iii) Honey -95.08%
iv) Curcuma longa -1.58%
v) Alahgiumdecapetalum -1.58%
vi) Raw salt -0.47%
vii) Black Salt -0.62%

The manufacturing method includes grinding the ingredients for 36 hours in Alahgiumdecapetalum extract and drying the same in sunlight, putting the mixture so obtained in a small closed mud pot and burning it with buffalo stool so as form a powder for its application. This powder is mixed in large quantity of honey and administered in to Patients with Parkinson's disease as prescribed. The powder is divided into required number of dosage. Optionally, the actives so extracted are further applied in the method in extract form.

The ingredients of the synergistic composition in accordance with the present invention have been arrived at through a rigorous course of experimentation and analysis. The quality of the individual ingredients incorporated in the composition in accordance with the present invention is also based on extensive research work.
It has been surprisingly deciphered by such experimentation and research that the combination of ingredients, applied in combination with or without the suitable excipients show the remarkable capacity of correcting defective nervous system effectively in patients, suffering from say Parkinson's disease. Thus effective treatment of nervous diseases such as Parkinson's disease is achieved in a technically effective and cost effective manner without exhibition of any severe side effect. This technical advancement and economic significance was hitherto not known or conceived by persons skilled in the art.

The different ingredients combined in effective proportions with or without other effective excipients yield the following combined effects:

i) rejuvenate brain activity, ii) produces oxygen and clears all blocks in the nervous system, iii) increases fresh blood circulation, iv)strengthens the damaged nerves and brings the disease under control, v) maintains the appropriate blood temperature.

The effectiveness and uniqueness of the present invention have been exemplified in the following examples, which are by way of understanding only and not by way of any sort of limitation. Further, the following details are there of experimental trial of the composition of the present invention.

Example 1: A male (aged 45) residing at Chennai, was suffering from Parkinson's disease. He couldn't speak or walk properly. After taking the medicine, in accordance with the present invention as an experimental trial, in proper dose for three months, he was able to speak and walk. The improvement percentage was 30.

Example 2: A male (aged 40) residing at Mumbai was suffering from Parkinson's disease. He couldn't speak, or bend on the back while walking. He also had problem of shivering hands and legs and couldn't stand steadily for long time. After taking the medicine, in accordance with the present invention as an experimental trial, for three months, his condition had improved without any hazardous side effect. The improvement percentage was 40.

Example 3: A female (aged 70) was diagnosed to have a small cyst in her brain. So she had shivering hands and legs, couldn't walk or speak properly. She also couldn't chew or swallow. After taking the medicine, in accordance with the present invention as an experimental trial, regularly for one month, she had become near normal. The improvement percentage was 50.
The examples, the test results and the description in general as hereinbefore all unequivocally establish the surprising effect as contemplated hereinbefore.

The present invention has been described with reference to some examples and preferred embodiments, purely for the sake of understanding and not by way of any limitation and the present invention includes all legitimate developments within the scope of what has been described hereinbefore and claimed in the appended claims.

We claim:

1. A composition for treatment of neurological diseases such as Parkinson's disease including optimally effective proportions of suitable ingredients with or without effective proportions of suitable excipient(s) said ingredients including:
i) Mercuric oxide
ii) Soda Carbonate
iii) Raw salt

2. The composition for correction of defective nervous system, as claimed in claim 1, wherein said ingredients further include:
i) Honey
ii) Curcuma longa
iii) Black Salt
(iv) Alahgiumdecapetalum

3. The composition as claimed in claim 1 and 2 wherein Alahgiumdecapetalum serves as an extracting medium and said honey acts as a sweetening agent.

4. The composition as claimed in any preceding claim wherein the said ingredients are applied in dry powder and/or extract form.

5. The composition as claimed in claims 1 to 4, wherein the proportions by weight in which said ingredients are applied are as follows:

i) Mercuric oxide - 0.316%
ii) Soda Carbonate -0.316%
iii) Honey -95.08%
iv) Curcuma longa -1.58%
v) Alahgiumdecapetalum -1.58%
vi) Raw salt -0.47%
vii) Black Salt -0.62%

6. A method for preparation of a composition for treatment of neurological diseases such as Parkinson's disease, wherein said ingredients, said ingredients including:

i) Mercuric oxide
ii) Soda Carbonate
iii) Curcuma longa
iv) Alahgiumdecapetalum
v) Raw salt
vi) Black Salt wherein said method includes grinding of Mercuric oxide, Soda Carbonate, Curcuma longa, Raw salt and Black Salt for a suitable duration in Alahgiumdecapetalum extract and drying the same, putting the mixture so obtained in a small closed container and burning with buffalo stool so as form a powder for its application.

7. The method as claimed in claim 8 wherein said powder so obtained is mixed with good proportion of honey.

8. The method as claimed in claim 8 wherein pure ghee and/or butter is added as medium.