DESC:FIELD OF THE INVENTION:
The present invention relates to synergistic insecticidal compositions comprising bioactive amounts of (A) Emamectin benzoate; (B) any insecticide selected from the class of diamide; (C) at least one insecticide selected phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, nereis toxin and mixture thereof. The present invention further relates to process of preparing said composition along with at least one inactive excipients and formulation thereof.

BACKGROUND OF THE INVENTION:
Combination of insecticides are used to broaden the spectrum of control of insect, to improve the pest control with synergistic effect, reduce dosage, thereby reducing environmental impact, to broaden the spectrum of control, i.e. chewing and sucking insects at a time, decrease chances of development and management of resistance and to enhance residual control so lesser the number of sprays for crop protections and minimizing the pesticidal load in ecosystem. The combination of insecticides at times demonstrate an additive or synergistic effect that results in an improved control on the pests.

Insecticide or pesticides are used widely and very frequently in commercial agriculture and have enabled an enormous increase in crop yields and product quality which ultimately increased the ease to farmers in term of economic advantage as well as ease of farming activities.

There are many combinations of insecticide known in the art for the control of soil borne pests. For example, US20200329703A1 patent relates to novel fungicidal compositions, to their use in agriculture or horticulture for controlling diseases caused by phytopathogens, especially phytopathogenic fungi, and to methods of controlling diseases on useful plants, especially fruits and vegetables. Further it relates to an Emamectin benzoate insecticide along with insecticide Chlorantraniliprole, tetraniliprole and flubendiamide.
AU2015285316 patent relates to a pesticide an insecticidal, miticidal, nematicidal, molluscicidal, microbicidal, or bactericidal composition comprising at least two types of active compounds with amounts that are synergistically active, comprising chlorantraniliprole, Cyantraniliprole.

US10219516B2 patent relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. This patent discloses the composition comprising insecticide like Emamectin benzoate, chlorantraniliprole, flubendiamide, tetraniliprole and various other insecticidal compounds.

JP2017178802 patent relates to a new technique for efficiently controlling pests that are difficult or impossible to control with conventional techniques. A pest control composition comprising insecticides discloses Emamectin benzoate, chlorantraniliprole, flubendiamide, tetraniliprole and in combination with various insecticidal compounds.

EP2582242B1 patent relates to a combinations of active substances with insecticidal and acaricidal properties. The patent further relates to a combination of emamectin benzoate, chlorantraniliprole and Flubendiamide, in combination with various insecticidal and acaricidal compounds.

WO2019156246A1 patent relates to a composition for pest control, which exhibits a reliable controlling effect on a wide variety of pests at lower doses by using dicloromezotiaz in combination with another chemical agent.Further it provides a composition for pest control, which contains dicloromezotiaz and at least one other agrochemical compound as active ingredients.

There is however a need for improvement of these combinations. Single and multiple active combinations used over a long period of time has resulted in resistance. With the onset of resistance to certain pests, there is a need in the art for a combination of actives that decreases chances of resistance and improves the spectrum of disease and pest control. Objects of the invention.

However still there is a need for a composition comprises at least one insecticide from diamide; and at least one insecticide selected from compound having various mode of action which overcomes some of the existing problems and can be prepared easily without much complex manufacturing process.

In general use, the pesticide actives are used in the form of a dilute aqueous composition because it can attain a good interaction with the target organism, such as plants, fungi and insects. However, most active pesticide compounds that are used as pesticides are only sparingly or even insoluble in water. The low solubility of such compounds present the challenges and difficulties to formulator in formulating pesticide compounds in stable formulations that can be easily stored for a long time and which still have a high stability and effective activity until end use. This problem especially occurs and may get worsen if more than one active compound is present in the composition.
Therefore, one object of the present invention is to provide improved combinations of insecticides for the control of foliar feeder and soil born pests. Another object of the present invention is to provide a method and a composition for controlling insect pests.
Yet another object of the present invention is to provide improved combinations of insecticides that promote plant health.
Inventors of the present invention have surprisingly found that the novel synergistic
composition of Emamectin benzoate; insecticide from diamide group of compounds; and at least one insecticide selected from compound having various mode of action as described herein which can provide solution to the above mentioned problems.

SUMMARY OF THE INVENTION
Therefore an aspect of the present invention provides an insecticidal composition comprising (A) Emamectin benzoate; (B) any insecticide selected from the class of diamide; (C) at least one insecticide selected from the class of phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, nereis toxin and mixture thereof.
Accordingly, in a further aspect, the present invention provides a method of protecting a plant propagation material, a plant, parts of a plant and/or plant organs that grow at a later point in time against pest damage by applying to the plant propagation material a composition comprising an insecticidal composition defined in the first aspect.
As per one embodiment formulation for the an insecticidal composition is selected from Granule/ soil applied (GR), Controlled (Slow or Fast) release granules (CR), Capsule suspension (CS), Dispersible concentrate (DC), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion for seed treatment (ES), Emulsion, oil in water (EW), Flowable suspension/concentrate for seed treatment (FS), Jambo balls or bags (bags in water soluble pouch), Solution for seed treatment (LS), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (= flowable concentrate) (SC), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Water soluble powder (SP), Water dispersible granule (WG or WDG), Wettable powder (WP), Water dispersible powder for slurry treatment (WS),A mixed formulation of CS en SC (ZC), A mixed formulation of CS en SE (ZE), A mixed formulation of CS en EW (ZW).
The preferred formulation for the present insecticidal composition is selected from Granule/ soil applied (GR), Controlled (Slow or Fast) release granules (CR), micro-granule.
Accordingly, in a first aspect, the present invention provides an insecticidal composition comprising (A) Emamectin benzoate; (B) any insecticide selected from the class of diamide; (C) at least one insecticide selected from the class of phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, nereis toxin and mixture thereof.

DETAILED DESCRIPTION OF THE INVENTION:
The term "synergistic", as used herein, refers the combined action of two or more active agents blended together and administered conjointly that is greater than the sum of their individual effects.
"Bioactive amounts” as mentioned herein means that amount which, when applied treatment of crops, is sufficient to effect such treatment.
Therefore an aspect of the present invention provides an insecticidal composition comprising (A) Emamectin benzoate; (B) any insecticide selected from the class of diamide; (C) at least one insecticide selected from the class of phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, nereis toxin and mixture thereof.
In an embodiment of the present invention the insecticide from group of class of diamides may be selected from chlorantraniliprole, cyantraniliprole, cyclaniliprole, tetraniliprole, tetrachlorantraniliprole, tyclopyrazoflor, cyhalodiamide, flubendiamide, fluchlordiniliprole.
In an embodiment of the present invention the insecticide from the class of Phenylpyrazole may be selected from ethiprole, fipronil, flufiprole, nicofluprole, pyrafluprole, pyriprole.
In an embodiment of the present invention the insecticide from the class of pyrethroids may be selected from bifenthrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin, deltamethrin, fenpropathrin, fenvalerate, tau-fluvalinate, permethrin, phenothrin, prallethrin, profluthrin, pyrethrin (pyrethrum).
In an embodiment of the present invention of insecticide from the class of nicotinic insecticides may be selected from neonicotinoids acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, thiamethoxam, flupyrimin, cycloxaprid, paichongding, guadipyr, cycloxylidin.
In further embodiment of the present invention the insecticide from sulfoximines may be selected from sulfoxaflor.
In further embodiment of the present invention the insecticide from butenolides may be selected from flupyradifurone.
In further embodiment of the present invention the insecticide from mesoionics may be selected from triflumezopyrim, dichloromezotiaz, fenmezoditiaz.
In further embodiment of the present invention the insecticide from spinosyns may be selected from spinosad, spinetoram.
In further embodiment of the present invention the insecticide from nereis toxin may be selected from bensultap, monosultap, cartap hydrochloride, thiocyclam, thiocyclam hydrogen oxalate, thiocyclam hydrochloride, thiosultap sodium.
More particularly an aspect of the present invention provides an insecticidal composition comprising (A) Emamectin benzoate (B) at least one insecticide from group of a diamide (C) at least one insecticidal compound selected from phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, nereis toxin or mixture thereof.
Most preferably, in a further aspect of the present invention is containing an insecticidal composition of (A) Emamectin benzoate ; (B) at least one insecticide from group of chlorantraniliprole, Tetraniliprole and flubendiamide; (C) at least one insecticidal compound selected from phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, nereis toxin or mixture thereof.
The present invention provides formulation for the aforesaid composition and method of preparation thereof.
Emamectin benzoate is an insecticide, with a mechanism of action and a strong activity against Lepidoptera as well as with and a high selectivity on useful organisms. This molecule acts if swallowed and has some contact action. It penetrates leaf tissues (translaminar activity) and forms a reservoir within the leaf. The mechanism of action is unique in the panorama of insecticides. In facts, it inhibits muscle contraction, causing a continuous flow of chlorine ions in the GABA and H-Glutamate receptor sites.
Diamide group of insecticides:
Anthranilic diamides are an important commercial synthetic class of insecticides (IRAC Group 28) that bind to the ryanodine receptor with selective potency against insect versus mammalian forms of the receptor. Chlorantraniliprole is first of the anthranilic diamide insecticides. It is a ryanodine receptor activator and is used to protect a wide variety of crops, including corn, cotton, grapes, rice and potatoes. It has a role as a ryanodine receptor agonist. It is an organobromine compound, a member of pyridines, a member of pyrazoles, a pyrazole insecticide, a member of monochlorobenzenes and a secondary carboxamide.
Chlorantraniliprole is a novel anthranilic diamide insecticide that functions via activation of the insect ryanodine receptors within the sarcoplasmic reticulum causing impaired regulation of muscle contraction. Ryanodine receptor channels regulate the release of internal calcium stores and are important in muscle contraction. Sustained release of calcium levels within the cytosol leads to muscle contraction, paralysis and eventual death of the organism. While insects possess a single form of the ryanodine receptor distributed in muscle and neuronal tissue, mammals possess three forms which are widely distributed in muscle and non-muscle tissues.
The present inventors believe that the combination of the present invention surprisingly results in a synergistic action. The combinations of the present invention allow for a broad spectrum of pest control and has surprisingly improved plant vigour and yield. The broad spectrum of the present combination also provides a solution for preventing the development of resistance.
The synergistic composition has very advantageous curative, preventive and systemic fungicidal properties for protecting cultivated plants. As has been mentioned, said active ingredient composition can be used to inhibit or destroy the pathogens that occur on plants or parts of plants (fruit, blossoms, leaves, stems, tubers, roots) of different crops or useful plants, while at the same time those parts of plants which grow later are also protected from attack by such pathogens. Active ingredient composition has the special advantage of being highly active against diseases in the soil that mostly occur in the early stages of plant development.
The synergistic composition of pesticide are used to protect the crops and plants from insect and fungus pests. The lists of the major crops on which the present innovative compositions may be used include but are not limited to GMO (Genetically Modified Organism) and Non GMO varieties of Cotton (Gossypium spp.), Paddy (Oryza sativa), Wheat (Triticum aestavum), Maize (Zea mays), Sugarcane (Saccharum officinarum), Soybean (Glycin max), Peanut (Arachis hypogaea), Mustard (Brassica juncea), Green gram (Vigna radiata), Chickpea (Cicer aritinum), Brinjal (Solanum melongena), Cabbage (Brassica oleracea var. capitata), Cauliflower (Brassica oleracea var. botrytis), Okra (Abelmoschus esculentus) , Onion (Allium cepa L.), Tomato (Solanum lycopersicum), Potato (Solanum tuberosum), Chilly (Capsicum annum), Garlic (Allium sativum), Bottle gourd (Lagenaria siceraria), Banana (Musa spp.), Citrus groups (Citrus spp.), Grape (Vitis vinifera), Guava (Psidium guajava), Pomegranate (Punica granatum), Turmeric (Curcuma longa), Ginger (Zingiber officinale), Cumin (Cuminum cyminum).
The composition according to the invention can be applied to any and all developmental stages of pests, such as egg, larva, pupa, and adult. The pests may be controlled by contacting the target pest, its food supply, habitat, breeding ground or its locus with a pesticidally effective amount of the inventive mixtures or of compositions comprising the mixtures.
The synergistic combination of the present invention used to control the insects-pests belongs to the order of the Hemiptera, for example, rice leafhopper Nephotettix nigropictus, rice brown plant hopper Nilaparvata lugen, rice white backed plant hopper, Apple Mealy bug Phenococcus aceris, bean aphid Aphis fabae, black citrus aphid Toxoptera aurantii, citrus black scale Saissetia oleae, cabbage aphid Brevicoryne brassicae, Lipaphis erysimi, citrus red scale Aonidiella aurantii, yellow scale Aonidiella citrine, citrus mealybug Planococcus citri, corn leaf aphid Rhopalosiphum maidis, cotton aphid Aphis gossypii, cotton jassid Amrasca biguttula biguttla, cotton mealy bug Planococcus spp. And Pseudococcus spp., cotton stainer Dysdercus suturellus, cotton whitefly Bemisia tabaci, cowpea aphid Aphis crassivora, grain aphid Sitobion avenae, golden glow aphid Uroleucon spp., grape mealybug Pseudococcus maritimus, green peach aphid Myzus persicae, greenhouse whitefly Trialeurodes vaporariorum, papaya mealy bug Pracoccus marginatus, pea aphid Acyrthosiphon pisum, sugarcane mealybug Saccharicoccus sacchari, potato aphid Myzus persicae, potato leaf hopper Empoasca fabae, cotton whitefly Bemisia tabaci, tarnished plant bug Lygus lineolaris, wooly apple aphid Eriosoma lanigerum, mango hopper Amritodus atkinsoni, Idioscopus spp..
Order Lepidoptera, for example army worm Mythimna unipuncta, asiatic rice borer Chilo suppressalis, bean pod borer Maruca vitrata, beet armyworm Spodoptera exigua, black cutworm Agrotis ipsilon, bollworm Helicoverpa armigera , cabbage looper Trichoplusia ni, codling moth Cydia pomonella, croton caterpillar Achea janata, diamond backmoth Plutella xylostella, cabbage worm Pieris rapae, pink bollworm Pectinophora gossypiella, sugarcane borer Diatraea saccharalis, tobacco budworm Heliothis virescens, tomato fruitworm Helicoverpa zea, velvet bean caterpillar Anticarsia gemmatalis, yellow stem borer Scirpophaga incertulas, spotted bollworm Earias vittella, rice leaffolder Cnaphalocrocis medinalis, pink stem borer Sesamia spp., tobacco leafeating caterpillar Spodoptera litura; brinjal fruit and shoot borer Leucinodes orbonalis, bean pod borer Maruca vitrata, Maruca testulalis, armyworm Mythimna separata, cotton pinkbollworm Pectinophora gossypiella, citrus leafminer Phyllocnistis citrella, cabbage butterfly Pieris bras-sicae, diamond backmoth Plutella xylostella, paddy stem borer Scirpophaga excerptallis, Scirpophaga incertulas, Scirpophaga innotata, wheat stem borer Sesamia inferens, Sitotroga cerealella, Spilosoma obliqua, Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Trichoplusia ni, Tryporyza novella, Tuta absoluta.
From the order Coleoptera, for example, apple twig borer Amphicerus spp., corn root worm Diabrotica virgifera, cucumber beetle diabrotica balteata, boll weevil Anthonomus grandis, grape flea beetle Altica chalybea, grape root worm Fidia viticola, grape trunk borer Clytoleptus albofasciatus, radish flea beetle Phyllotreta armoraciae, maize weevil Sitophilus zeamais, northern corn rootworm Diabrotica barberi, rice water weevil Lissorhoptrus oryzophilus, Anthonomus grandis, Bruchus lentis, Diabrotica semipunctata, Diabrotica virgifera, Dicladispa armigera, Epila-chna varivestis, various species of white grubs are Holotrichia bicolor, Holotrichia consanguinea, Holotrichia serrata, Leptinotarsa decemlineata, Phyllotreta chrysocephala, Popillia japonica etc
From the order Orthoptera, for example, Gryllotalpa spp., Locusta spp., and Schistocerca is spp.
From the order Thysanoptera, for example, Frankliniella spp., Thrips palmi, Thrips tabaci and Scirtothrips dorsalis.
From termites (Isoptera), for example Calotermes flavicollis, Coptotermes formosanus, Heterotermes aureus, Leucotermes flavipes, Microtermes obesi, Odontotermes obesus, Reticulitermes flavipes, Termes natalensis
From the order Heteroptera, for example, Dysdercus spp., Leptocorisa spp.
From the order Hymenoptera, for example, Solenopsis spp.
From the order Diptera, for example, Antherigona soccata, Dacus spp., Liriomyza spp., Melanagromyza spp.
From the order Acarina, for example, Aceria mangiferae, Brevipalpus spp., Eriophyes spp., Oligonychus mangiferus, Oligonychus punicae, Panonychus citri, Panonychus ulmi, Polyphagotarsonemus latus, Tarsonemus spp., Tetranychus urticae, Tetranychus cinnabarinus;
Plant parasitic nematodes such as root-knot nematodes, Meloidogyne incognita, Meloidogyne javanica and other Meloidogyne species; cyst nematodes, Globodera rostochiensis, Globodera pallida, Globodera tabacum and other Globodera species, Heterodera avenae, Heterodera glycines, Heterodera schachtii, Heterodera trifolii, and other Heterodera species; seed gall nematodes, Anguina funesta, Anguina tritici and other Anguina species; stem and foliar nematodes, Aphelenchoides besseyi, Aphelen-choides fragariae, Aphelenchoides ritzemabosi and other Aphelenchoides species; sting nematodes, Belonolaimus longicaudatus and other Belonolaimus species; pine nematodes, Bursaphelenchus xylophilus and other Bursaphelenchus species; ring ne-matodes, Criconema species, Criconemella species, Criconemoides species, and Me-socriconema species; stem and bulb nematodes, Ditylenchus destructor, Ditylenchus dipsaci, Ditylenchus myceliophagus and other Ditylenchus species; awl nematodes, Dolichodorus species; spiral nematodes, Helicotylenchus dihystera, Helicotylenchus multicinctus and other Helicotylenchus species, Rotylenchus robustus and other Roty-lenchus species; sheath nematodes, Hemicycliophora species and Hemicriconemoides species; Hirshmanniella species; lance nematodes, Hoplolaimus columbus, Hoplolai-mus galeatus and other Hoplolaimus species; false root-knot nematodes, Nacobbus aberrans and other Nacobbus species; needle nematodes, Longidorus elongates and other Longidorus species; pin nematodes, Paratylenchus species; lesion nematodes, Pratylenchus brachyurus, Pratylenchus coffeae, Pratylenchus curvitatus, Pratylenchus goodeyi, Pratylencus neglectus, Pratylenchus penetrans, Pratylenchus scribneri, Pratylenchus vulnus, Pratylenchus zeae and other Pratylenchus species; Radinaphelenchus cocophilus and other Radinaphelenchus species; burrowing nematodes, Radopholus similis and other Radopholus species; reniform nematodes, Rotylenchulus reniformis and other Rotylenchulus species; Scutellonema species; stubby root nematodes, Tri-chodorus primitivus and other Trichodorus species; Paratrichodorus minor and other Paratrichodorus species; stunt nematodes, Tylenchorhynchus claytoni, Tylenchorhyn-chus dubius and other Tylenchorhynchus species and Merlinius species; citrus nematodes, Tylenchulus semipenetrans and other Tylenchulus species; dagger nematodes, Xiphinema americanum, Xiphinema index, Xiphinema diversicaudatum and other Xi-phinema species; and other plant parasitic nematode species.
Formulation of the present invention can be in any of the formulations selected from Granule/ soil applied (GR), Controlled (Slow or Fast) release granules (CR), Capsule suspension (CS), Dispersible concentrate (DC), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion for seed treatment (ES), Emulsion, oil in water (EW), Flowable suspension/concentrate for seed treatment (FS), Jambo balls or bags (bags in water soluble pouch), Solution for seed treatment (LS), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (= flowable concentrate) (SC), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Water soluble powder (SP), Water dispersible granule (WG or WDG), Wettable powder (WP), Water dispersible powder for slurry treatment (WS), A mixed formulation of CS en SC (ZC), A mixed formulation of CS en SE (ZE), A mixed formulation of CS en EW (ZW).
The preferred formulation for the present insecticidal composition is selected from Granule/ soil applied (GR), Controlled (Slow or Fast) release granules (CR), micro-granule.
Further composition comprising of (A) an insecticide Emamectin benzoate ; (B) an insecticide from diamide group; and (C) at least one insecticidal compound selected from phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, nereis toxin or mixture thereof ; which are bio active ingredient for the present composition are present in specific fixed ratio.
Further (A) Emamectin benzoate in an amount of 0.01% to 5% by weight; (B) an insecticide from diamide group present in an amount of 0.1 % - 20 % by weight; and (C) an insecticide selected from classes of phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, nereis toxin or mixture thereof present in an amount of 1-20% by weight; along with inactive excipients are present in fixed specific percentage by weight.
Compounds Compound A Compound B Compound C
Composition Emamectin benzoate an insecticide selected from the class of diamide A group of insecticides
Ratio 0.01% to 5% w/w 0.1% to 20% w/w 1% to 20% w/w

The term "health of a plant" or "plant health" is defined as a condition of the plant and/or its products. As a result of the improved health, yield, plant vigor, quality and tolerance to abiotic or biotic stress are increased. Noteworthy, the health of a plant when applying the method according to the invention, is increased independently of the pesticidal properties of the active ingredients used because the increase in health is not based upon the reduced pest pressure but instead on complex physiological and metabolic reactions which result for example in an activation of the plant's own natural defense system. As a result, the health of a plant is increased even in the absence of pest pressure. Accordingly, in an especially preferred embodiment of the method according to the invention, the health of a plant is increased both in the presence and absence of biotic or abiotic stress factors. The above identified indicators for the health condition of a plant may be interdependent or they may result from each other. An increase in plant vigor may for example result in an increased yield and/or tolerance to abiotic or biotic stress. One indicator for the condition of the plant is the yield. "Yield" is to be understood as any plant product of economic value that is produced by the plant such as grains, fruits in the proper sense, vegetables, nuts, grains, seeds, wood (e.g. in the case of silviculture plants) or even flowers (e.g. in the case of gardening plants, ornamentals). The plant products may in addition be further utilized and/or processed after harvesting.
In an especially preferred embodiment of the invention, the yield of the treated plant is increased.
In another preferred embodiment of the invention, the yield of the plants treated according to the method of the invention, is increased synergistically.
According to the present invention, "increased yield" of a plant, in particular of an agricultural, silvicultural and/or horticultural plant means that the yield of a product of the respective plant is increased by a measurable amount over the yield of the same product of the plant produced under the same conditions, but without the application of the mixture according to the invention.
Increased yield can be characterized, among others, by the following improved proper-ties of the plant: increased plant, weight, increased plant height, increased biomass such as higher overall fresh weight (FW), increased number of flowers per plant, higher grain yield, more tillers or side shoots (branches), larger leaves, increased shoot growth, increased protein content, increased oil content, increased starch content, increased pigment content, increased leaf are index.
According to the present invention, the yield is increased by at least 5 %, preferable by 5 to 10 %, more preferable by 10 to 20 %, or even 20 to 30 % compared to the untreated control plants or plants treated with pesticides in a way different from the method according to the present invention. In general, the yield increase may even be higher.
The advantages of innovative combination includes the one shot control of soil hibernating (termites, whitegrub, root weevil, root feeder) and foliage feeding insects (stem borers, internode borers, sap suckers etc.). It also delays or prevent the resistance development in insect-pests.It helps to increase the yield of treated plants (cereals, pulses, oilseeds, fiber crop, sugar crops, leafy vegetables, tuber crops, fruit crops, flowers, ornamentals etc.) which helps to increase in yield due to more number of tillers, more branches and sub branches, more number of flowers, and more number of fruits. It also Increases the plant vigor and improves the quality (means visual appearance, color, size, shape etc.) in grains, fruits, fiber, flowers, tuber, bulb, rhizomes, straw, leaves and other plant parts and plant products.
The process for preparing the present Granular agrochemical composition comprising can be modified accordingly by any person skilled in the art based on the knowledge of the manufacturing the formulation. However all such variation and modification is still covered by the scope of present invention.
Granular compositions of Emamectin benzoate+Diamide+Insecticide
Compound A Compound B Compound C Active ingredients (%) Formulation Strength (%)
A B C
Emamectin benzoate Chlorantraniliprole Clothianidin 0.16 0.32 0.80 1.28
Emamectin benzoate Chlorantraniliprole Thiamethoxam 0.16 0.32 0.80 1.28
Emamectin benzoate Chlorantraniliprole Imidacloprid 0.16 0.32 0.50 0.98
Emamectin benzoate Chlorantraniliprole Triflumezopyrim 0.16 0.32 0.24 0.72
Emamectin benzoate Chlorantraniliprole Flupyrimin 0.16 0.32 1.00 1.48
Emamectin benzoate Chlorantraniliprole Dichloromezotiaz 0.15 0.25 0.5 0.90
Emamectin benzoate Chlorantraniliprole Fenmezoditiaz 0.15 0.25 0.5 0.90
Emamectin benzoate Chlorantraniliprole Cartap hydrochloride 0.12 0.2 4 4.32
Emamectin benzoate Chlorantraniliprole Thiocyclam hydrogen oxalate 0.12 0.2 4 4.32
Emamectin benzoate Chlorantraniliprole Fipronil 0.3 0.5 1 1.80
Emamectin benzoate Chlorantraniliprole Spinetoram 0.3 0.5 1 1.80
Emamectin benzoate Cyantraniliprole Fipronil 0.15 0.5 0.5 1.15
Emamectin benzoate Cyantraniliprole Clothianidin 0.15 0.5 0.5 1.15
Emamectin benzoate Cyantraniliprole Thiamethoxam 0.15 0.5 0.5 1.15
Emamectin benzoate Cyantraniliprole Imidacloprid 0.15 0.5 0.375 1.03
Emamectin benzoate Cyantraniliprole Triflumezopyrim 0.15 0.5 0.2 0.85
Emamectin benzoate Cyantraniliprole Flupyrimin 0.15 0.5 0.75 1.40
Emamectin benzoate Cyantraniliprole Dichloromezotiaz 0.15 0.5 0.5 1.15
Emamectin benzoate Cyantraniliprole Fenmezoditiaz 0.15 0.5 0.5 1.15
Emamectin benzoate Cyantraniliprole Spinetoram 0.15 0.5 0.5 1.15
Emamectin benzoate Cyantraniliprole Cartap hydrochloride 0.15 0.5 4 4.65
Emamectin benzoate Cyantraniliprole Thiocyclam hydrogen oxalate 0.15 0.5 4 4.65
Emamectin benzoate Tetraniliprole Clothianidin 0.3 0.6 1 1.90
Emamectin benzoate Tetraniliprole Thiamethoxam 0.3 0.6 1 1.90
Emamectin benzoate Tetraniliprole Imidacloprid 0.3 0.6 1 1.90
Emamectin benzoate Tetraniliprole Triflumezopyrim 0.3 0.6 0.5 1.40
Emamectin benzoate Tetraniliprole Flupyrimin 0.3 0.6 1.5 2.40
Emamectin benzoate Tetraniliprole Dichloromezotiaz 0.12 0.45 0.5 1.07
Emamectin benzoate Tetraniliprole Fenmezoditiaz 0.12 0.45 0.5 1.07
Emamectin benzoate Tetraniliprole Cartap hydrochloride 0.15 0.3 4 4.45
Emamectin benzoate Tetraniliprole Thiocyclam hydrogen oxalate 0.15 0.3 4 4.45
Emamectin benzoate Tetraniliprole Fipronil 0.3 0.6 1 1.90
Emamectin benzoate Tetraniliprole Spinetoram 0.3 0.6 1 1.90
Emamectin benzoate Flubendiamide Clothianidin 0.2 0.8 0.8 1.80
Emamectin benzoate Flubendiamide Thiamethoxam 0.2 0.8 0.8 1.80
Emamectin benzoate Flubendiamide Imidacloprid 0.2 0.8 0.5 1.50
Emamectin benzoate Flubendiamide Triflumezopyrim 0.2 0.8 0.24 1.24
Emamectin benzoate Flubendiamide Flupyrimin 0.2 0.8 1.2 2.20
Emamectin benzoate Flubendiamide Dichloromezotiaz 0.12 0.75 0.5 1.37
Emamectin benzoate Flubendiamide Fenmezoditiaz 0.12 0.75 0.5 1.37
Emamectin benzoate Flubendiamide Cartap hydrochloride 0.12 0.75 4 4.87
Emamectin benzoate Flubendiamide Thiocyclam hydrogen oxalate 0.12 0.75 4 4.87
Emamectin benzoate Flubendiamide Fipronil 0.24 1.5 1 2.74
Emamectin benzoate Flubendiamide Spinetoram 0.24 1.5 1 2.74
Emamectin benzoate Chlorantraniliprole Flupyrimin 2 5 16 23.00
Emamectin benzoate Cyantraniliprole Flupyrimin 2 10 16 28.00
Emamectin benzoate Tetraniliprole Flupyrimin 2 6 16 24.00
Emamectin benzoate Flubendiamide Flupyrimin 2 6 16 24.00
Emamectin benzoate Chlorantraniliprole Triflumezopyrim 10 25 20 55.00
Emamectin benzoate Cyantraniliprole Triflumezopyrim 5 25 10 40.00
Emamectin benzoate Tetraniliprole Triflumezopyrim 5 18 10 33.00
Emamectin benzoate Flubendiamide Triflumezopyrim 5 20 10 35.00

The granular agrochemical composition of the present invention in addition to bioactive amounts of active ingredients further comprises inactive excipients including but not limited to dispersing agent, emulsifier, buffering agent, controlled release agent, inert material, solvent, humectant, anti-foaming agent, carrier and colouring agent.
Example of dispersing agent used herein for present Granule formulation is selected from Copolymer of propylene oxide (PO) and ethylene oxide (EO) and/or an ethoxylated tristyrene phenol, copolymer of PO and EO is alpha-butyl-omega-hydroxypoly (oxypropylene) block polymer with poly(oxyethylene), ethoxylated tristyrene phenol is alpha-[2,4,6-tris[1-(phenyl)ethyl] phenyl]-omega-hydroxy poly(oxyethylene, poly(oxy-1,2-ethanediyl)-alpha-C10-15alkyl-omega-hydroxy phosphate or sulphate and/or a C10-13alkylbenzenesulfonic acid, tristyrylphenols, nonylphenols, dinonylphenol and octylphenols, styrylphenol polyethoxyester phosphate, alkoxylated C14-20 fatty amines, alkylnaphthalene sulfonate sodium salt, sodium polycarboxylate, naphthalene sulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalene sulfonic acid formaldehyde condensate, phenol sulfonic acid urea formaldehyde condensate, methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, polyacrylates and phosphate esters, calcium lignosulfonate, sodium lignosulfonate, sodium lignosulfonate-sulfomethylated.
More preferred dispersing agent for Granule formulation is selected from Copolymer of propylene oxide (PO) and ethylene oxide (EO) and/or an ethoxylated tristyrene phenol, copolymer of PO and EO is alpha-butyl-omega-hydroxypoly (oxypropylene) block polymer with poly(oxyethylene), naphthalene condensates, polyacrylates and phosphate esters, calcium lignosulfonate, sodium lignosulfonate, sodium lignosulfonate-sulfomethylated present in more preferred range in an amount of 0.1-8.0%w/w.
Most preferred dispersing agent for Granule formulation is selected from Copolymer of propylene oxide (PO) and ethylene oxide (EO) and/or an ethoxylated tristyrene phenol, copolymer of PO and EO is alpha-butyl-omega-hydroxypoly(oxypropylene) block polymer with poly(oxyethylene) present in most preferred range in an amount of 0.5-4.0%w/w.
Example of emulsifier or emulsifying agent used herein for present Granule formulation is selected from mono C2-6 alkyl ether of a poly C2-4alkylene oxide block copolymer, condensation product of castor oil and poly C2-4alkylene oxide, alkoxylated castor oil is available under the trade name Agnique CSO-36, a mono- or di-ester of a C12-24fatty acid and polyC2-4alkylene oxide, carboxylates, sulphates, sulphonates, alcohol ethoxylates, Dodecyl hydroxypoly (oxy-1,2 ethanediyl) phosphate, alkyl phenol ethoxylates, fatty acid ethoxylates, sorbitan esters, ethoxylated fats or oils, amine ethoxylates, phosphate esters, ethylene oxide - propylene oxide copolymers, fluorocarbons,alkyd-polyethylene glycol resin, polyalkylene glycol ether, apolyalkoxylated nonyl phenyl, alkoxylated primary alcohol, ethoxylated distyrylphenol, ethoxylated distyrylphenol sulphate, ethoxylated tristyrylphenol phosphate, tristyrylphenol phosphate ester, hydroxylated stearic acid polyalkylene glycol polymer, and their corresponding salts,alkyd-polyethylene glycol resin, polyalkylene glycol ether, ethoxylated distyrylphenol, ethoxylated distyrylphenol sulphate, ethoxylated tristyrylphenol phosphate, tristyrylphenol phosphate ester, tristyrylphenol phosphate potassium salt, dodecysulfate sodium salt.
More preferred emulsifier or emulsifying agent for Granule formulation is selected from ethoxylated tristyrylphenol phosphate, tristyrylphenol phosphate ester, hydroxylated stearic acid polyalkylene glycol polymer, and their corresponding salts,alkyd-polyethylene glycol resin, polyalkylene glycol ether, ethoxylated distyrylphenol, ethoxylated distyrylphenol sulphate, ethoxylated tristyrylphenol phosphate, tristyrylphenol phosphate ester, tristyrylphenol phosphate potassium salt, dodecysulfate sodium salt present in more preferred range in an amount of 0.05-8.0%w/w.
Most preferred emulsifier or emulsifying agent for Granule formulation is selected from ethoxylated distyrylphenol, ethoxylated distyrylphenol sulphate, ethoxylated tristyrylphenol phosphate present in most preferred range in an amount of 0.1-4.0%w/w.
Examples of dispersing agent used herein for present micro-granule formulation is selected from sodium polycarboxylate (sodium polyacrylate), naphthalene sulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalene sulfonic acid formaldehyde condensate, methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, sodium lignosulfonates, calcium lignosulfonate, lignin sulfonate sodium salt, alkyl naphthalene sulfonate-sodium salt. The preferred dispersing agent is alkyl naphthalene sulfonate. It provides an excellent wetting, dispersing, hydrotroping and medium to low foaming. It offers acid and base stability, hard water tolerance and high temperature stability.
More preferred dispersing agent used herein for present micro-granule formulation is selected from methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, sodium lignosulfonates, calcium lignosulfonate, lignin sulfonate sodium salt, alkyl naphthalene sulfonate-sodium salt present in more preferred range in an amount of 0.05-8.0%w/w.
Most preferred dispersing agent used herein for present micro-granule formulation is selected from sodium lignosulfonates, calcium lignosulfonate, alkyl naphthalene sulfonate-sodium salt present in most preferred range in an amount of 0.1-4.0%w/w.
Examples of wetting agent used herein for present micro-granule formulation is selected from sodium N-methyl-N-oleoyl taurate, alkylated naphthalene sulfonate, sodium salt, mixture of isomers of dibutyl naphthalene sulphonic acid sodium salt, sodium di-isopropyl naphthalene sulphonate, sodium Lauryl sulfate, dioctyl sulfate, alkyl naphthalene sulfonates, phosphate esters, sulphosuccinates and non-ionic such as tridecyl alcohol ethoxylate, alkyl or alkaryl sulfonates such as alkylbenzene sulfonates, alpha olefin sulfonate and alkyl naphthalene sulfonates, ethoxylated or non-ethoxylated alkyl or alkaryl carboxylates, alkyl or alkaryl phosphate esters, alkyl polysaccharide, di or mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, alkyl naphthalene sulfonates, dialkyl sulphosuccinates, butyl, dibutyl, isopropyl and di-isopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate or C10-C16 alkyl benzene sulfonate, organosilicons surfactants includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, trisiloxane heptamethyl, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, may or may not be in modified form, may be liquid or powder form or mixture thereof.
More preferred wetting agent used herein for present micro-granule formulation is selected from methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, sodium lignosulfonates, calcium lignosulfonate, lignin sulfonate sodium salt, alkyl naphthalene sulfonate-sodium salt present in more preferred range in an amount of 0.05-8.0%w/w.
Most preferred wetting agent used herein for present micro-granule formulation is selected from Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, polydimethylsiloxane present in most preferred range in an amount of 0.1-6.0%w/w.
Examples of Antifoaming agent used herein for present micro-granule formulation is polydimethylsiloxane present in an amount of 0.01-2.0%w/w
Example of solvents used herein for present Granule formulation is selected from fatty acid methyl ester, cyclohexane, xylene, mineral oil or kerosene, mixtures or substituted naphthalene, mixtures of mono- and poly alkylated aromatics, dibutyl phthalate or dioctyl phthalate, ethylene glycol monomethyl or mono ethyl ether, butyrolactone, octanol, castor oil, soybean oil, cottonseed oil, epoxidised coconut oil or soybean oil, aromatic hydrocarbons, dipropylene glycol mono methylether, polypropylene glycol [M.W. 2000-4000], polyoxyethylene polyoxypropylene glycols, polyoxypropylene polyoxyethylene glycols, diethyleneglycol, polyethylene glycol [M.W. 200-4000 amu], methoxy polyethylene glycols 350, 550, 750, 2000, 5000; glycerol, methyl oleate, n-octanol, alkyl phosphates such as tri-n-butyl phosphate, propylene carbonate and isoparaffinic, tetrahydrofurfuryl alcohol, gamma-butyrolactone, N-methyl-2-pyrrolidone, tetramethylurea, dimethylsulfoxide, N,N-dimethylacetamide, diacetone alcohol, polybutene, propylene carbonate, dipropylene glycol isomer mixture, water.
More preferred solvent used herein for present Granule formulation is selected from N-methyl-2-pyrrolidone, tetramethylurea, dimethylsulfoxide, N,N-dimethylacetamide, diacetone alcohol, polybutene, propylene carbonate, dipropylene glycol isomer mixture, water present in more preferred range in an amount of 0.05-8.0%w/w.
Most preferred solvent used herein for present Granule formulation is selected from N-methyl-2-pyrrolidone; N,N-dimethylacetamide present in most preferred range in an amount of 0.1-4.0%w/w.
Example of Carrier or filler agent used herein for present Granule formulation is selected from diatomaceous earth, attapulgite or zeolites, dolomite, limestone, silica, river sand (Silica), sand, fly ash, hydrated lime, wheat flour, wood flour, ground wheat straw, cellulose and soy flour, bentonite, kaolin, attapulgite, diatomaceous earth, calcium carbonate, calcium silicate, magnesium stearate, talc, muscovite mica, fused sodium potassium, aluminum silicate, perlite, talc, muscovite mica, urea, sulfur-coated urea, isobutylidene diurea, ammonium nitrate, ammonium sulfate, ammonium phosphate, triple super phosphate, phosphoric acid, potassium sulfate, potassium nitrate, potassium metaphosphate, potassium chloride, dipotassium carbonate, potassium oxide.
More preferred Carrier or filler agent used herein for present Granule formulation is selected from silica, river sand (Silica), sand, phosphoric acid, talc powder present in more preferred range in an amount of 60-92%w/w.
Most preferred Carrier or filler agent used herein for present Granule formulation is selected from silica, river sand (Silica) present in most preferred range in an amount of 80-90%w/w.

Example of Carrier or filler agent used herein for present micro-granule formulation is selected from china clay, silica, lactose anhydrous, ammonium sulfate, sodium sulfate anhydrous, corn starch, urea, EDTA, urea formaldehyde resin, diatomaceous earth, kaolin, bentonite, kieselguhr, fuller's earth, attapulgite clay, bole, loess, talc, chalk, dolomite, limestone, lime, calcium carbonate, powdered magnesia, magnesium oxide, magnesium sulphate, sodium chloride, gypsum, calcium sulphate, pyrophyllite, silicates and silica gels; fertilizers such as, for example, ammonium sulphate, ammonium phosphate, ammonium nitrate and urea; natural products of vegetable origin such as, for example, grain meals and flours, bark meals, wood meals, nutshell meals and cellulosic powders; and synthetic polymeric materials such as, for example, ground or powdered plastics and resins, bentonites, zeolites, titanium dioxide, iron oxides and hydroxides, aluminium oxides and hydroxides, or organic materials such as bagasse, charcoal, or synthetic organic polymers.
More preferred Carrier or filler agent used herein for present micro-granule formulation is selected from china clay, silica, lactose anhydrous, ammonium sulfate, sodium sulfate anhydrous, corn starch, urea, EDTA, urea formaldehyde resin, diatomaceous earth, kaolin, talc powder present in more preferred range in an amount of 15-40%w/w.
Most preferred Carrier or filler agent used herein for present micro-granule formulation is selected from china clay, urea formaldehyde resin present in most preferred range in an amount of 20-30%w/w.

Example of humectant used herein for present micro-granule formulation is selected from humic acid, glycerol, lactose, Sodium sulphate anhydrous.
Most preferred humectant used herein for present micro-granule formulation is selected from Sodium sulphate anhydrous present in most preferred range in an amount of 2-8 %w/w.
Example of colouring agent used herein for present Granule formulation is selected from crystal violet, thalocyano dye chlorinated, aerosol green FFB dye, rhodamine, azo compound. present in an amount of 0.01-1.0%w/w.
Most preferred colouring agent used herein for present Granule formulation is selected from aerosol green FFB dye, rhodamine present in most preferred range in an amount of 0.01-1.0%w/w.
Example of Controlled release agent used herein for present Granule formulation is selected from xanthan gum, PVK, carboxymethyl celluloses, polyvinyl alcohols, gelatin, sodium carboxymethyl cellulose, hydroxyethyl cellulose, Polyacrylic acid, sodium polyacrylate, modified starch, paraffin wax, polyvinyl acetate, montan wax and vinyl acetate, polyethylene glycol 6000, cationic hydrosoluble polymer, C4 alkylated polyvinyl pyrrolidone.
More preferred Controlled release agent used herein for present controlled Release Granule formulation is selected from carboxymethyl celluloses, polyvinyl alcohols, gelatin, sodium carboxymethyl cellulose, hydroxyethyl cellulose, Polyacrylic acid, sodium polyacrylate, modified starch, paraffin wax, polyvinyl acetate present in more preferred range in an amount of 0.05-8.0%w/w.
Most preferred Controlled release agent used herein for present controlled Release Granule formulation is selected from polyvinyl alcohols, Polyacrylic acid, paraffin wax present in most preferred range in an amount of 0.1-6.0%w/w.
Example of Inert agent used herein for present Granule formulation is selected from Precipitated silica, Nano polysaccharide, china clay, silica, lactose anhydrous, lactose monohydrate, ammonium sulphate, sodium sulphate anhydrous, corn starch, urea, EDTA, urea formaldehyde resin, diatomaceous earth, kaolin, bentonite, kieselguhr, fuller's earth, attapulgite clay, bole, loess, talc powder, chalk, dolomite, limestone, lime, calcium carbonate, powdered magnesia, magnesium oxide, magnesium sulphate, sodium chloride, gypsum, calcium sulphate, pyrophyllite, silicates and silica gels.
Most preferred inert agent used herein for present Granule formulation is selected from precipitated silica, china clay, silica, talc powder present in most preferred range in an amount of present in an amount of 0.5-3.0%w/w.
Example of buffering agent used herein for present Granule formulation is selected from calcium hydroxyapatite, phosphoric acid, sodium citrate, Potassium Dihydrogen Phosphate, Sodium Hydroxide, carbonated apatite, calcium carbonate, sodium bicarbonate, tricalcium phosphate, calcium phosphates, carbonated calcium phosphates, amine monomers, lactate dehydrogenase and magnesium hydroxide.
Most preferred buffering agent used herein for present Granule formulation is selected from phosphoric acid, sodium citrate present in most preferred range in an amount of present in an amount of 0.1-1.0%w/w.

Example 1: Composition of Emamectin benzoate 0.12%+Chlorantraniliprole 0.24%+Cartap hydrochloride 4% Granule
Ingredients Content % (w/w) Function
Emamectin Benzoate a.i. 0.12 active ingredient 1
Chlorantraniliprole a.i. 0.24 active ingredient 2
Cartap Hydrochloride a.i. 4.00 active ingredient 3
Tri-styryl Phenol Ethoxylate 3.00 emulsifier
Phosphoric acid 0.50 Buffering agent
N-methyl-2-pyrrolidone 3.00 solvent
Copolymer of propylene oxide (PO) and ethylene oxide (EO) 2.50 dispersing agent
Rhodamine 0.50 colourant
Precipitated silica 2.00 inert
Riversand (Silica) 84.14 carrier/filler
Total 100.00
a.i.-active ingredient on 100% purity basis

The storage stability study of composition of Emamectin benzoate 0.12%+Chlorantraniliprole 0.24%+Cartap hydrochloride 4% Granule meets the all inhouse parameters likes; active ingredients content, pH range, dustiness, dry sieve, attrition resistance, bulk density and moisture content, in laboratory condition (for 14 days) and room temperature (up to 12 months).

Manufacturing process for preparing 100 kg composition of Emamectin benzoate 0.12%+Chlorantraniliprole 0.24%+Cartap hydrochloride 4% Granule
Step 1-Add 0.12 kg of Emamectin Benzoate and 0.24 kg of Chlorantraniliprole technical into 3.0 kg of N-methyl-2-pyrrolidone, 0.5 kg of Rhodamine dye and add 3.0 kg of Tri-styryl Phenol Ethoxylate and homogenize the mixture.
Step 2-Now spray this mixture on 84.14 kg of River sand granules and blend it till homogeneity
Step 3-Now mix 2.5 kg of Copolymer of propylene oxide (PO) and ethylene oxide (EO) and 0.5 kg of Phosphoric acid and blend it on these treated granules and homogenize.
Step 4- Now blend 4.0 kg of Cartap Hydrochloride technical and then 2.0 kg of precipitated silica and homogenize it till homogeneity
Step 4- Finally add silica to make granules free flowing and free of moisture
Step 5- Final product is sent for QC approval.

Example 2: Composition of Emamectin benzoate 0.24% + Tetraniliprole 0.9% + Fipronil 1% Granule

Ingredients Content % (w/w) Function
Emamectin Benzoate a.i. 0.24 active ingredient 1
Tetraniliprole a.i. 0.90 active ingredient 2
Fipronil a.i. 1.00 active ingredient 3
Tri-styryl Phenol Ethoxylate 3.00 emulsifier
N-methyl-2-pyrrolidone 3.00 solvent
Copolymer of propylene oxide (PO) and ethylene oxide (EO) 1.00 dispersing agent
Rhodamine 0.50 colourant
Precipitated silica 2.00 innert
Riversand (Silica) 88.36 carrier/filler
Total 100.00
a.i.-active ingredient on 100% purity basis

The storage stability study of composition of Emamectin benzoate 0.24%+Tetraniliprole 0.9%+Fipronil 1% Granule meets the all inhouse parameters likes; active ingredients content, pH range, dustiness, dry sieve, attrition resistance, bulk density and moisture content, in laboratory condition (for 14 days) and room temperature (up to 12 months).

Example 3
Composition of Emamectin benzoate 0.16% + Chlorantraniliprole 0.4% + Clothianidin 0.8% Granule
Ingredients content % (w/w) Function
Emamectin Benzoate a.i. 0.16 active ingredient 1
Chlorantraniliprole a.i. 0.40 active ingredient 2
Clothianidin a.i. 0.80 active ingredient 3
Tri-styryl Phenol Ethoxylate 3.00 Emulsifier
Polyvinyl alcohols 1.00 controlled release agent
Nano polysaccharide 2.50 inert 1
N-methyl-2-pyrrolidone 3.00 Solvent
Copolymer of propylene oxide (PO) and ethylene oxide (EO) 1.00 dispersing agent
Rhodamine 0.50 Colourant
Precipitated silica 1.00 inert 2
Riversand (Silica) 86.64 carrier/filler
Total 100.00
a.i.-active ingredient on 100% purity basis

Storage stability-Emamectin benzoate 0.16%+Chlorantraniliprole 0.4%+Clothianidin 0.8% Granule
Laboratory storage stability
Parameters Specification (in house) Initial At 54±2 0C At 0±2 0C
Emamectin Benzoate a.i. 0.142 to 0.176 0.165 0.16 0.17
Chlorantraniliprole a.i. 0.38 to 0.44 0.42 0.41 0.42
Clothianidin a.i. 0.76 to 0.88 0.83 0.81 0.83
pH range (1% aq. Suspension) 4.0 to 7.0 5.50 5.50 5.50
Dustiness < 20 mg 10 10 10
Dry sieve (300 micron) percent by mass min. > 90% 99.5 99.2 99.3
Attrition Resistance (<100 micron) < 5% 2.10 2.10 2.10
Bulk density (g/ml) 1.25 to 1.50 1.35 1.35 1.35
Moisture content percent by mass max. max. 2% 1.50 1.50 1.50
Room temperature storage stability
Parameters specification (in house) 1 month 6 months 12 months
Emamectin Benzoate a.i. 0.142 to 0.176 0.165 0.165 0.163
Chlorantraniliprole a.i. 0.38 to 0.44 0.42 0.42 0.415
Clothianidin a.i. 0.76 to 0.88 0.83 0.83 0.825
pH range (1% aq. Suspension) 4.0 to 7.0 5.50 5.50 5.50
Dustiness < 20 mg 10 10 10
Dry sieve (300 micron) percent by mass min. > 90% 99.50 96.35 96.25
Attrition Resistance (<100 micron) < 5% 2.10 2.10 2.10
Bulk density (g/ml) 1.25 to 1.50 1.35 1.35 1.35
Moisture content percent by mass max. max. 2% 1.50 1.50 1.40

The storage stability study of Emamectin benzoate 0.16%+Chlorantraniliprole 0.4%+Clothianidin 0.8% Granule meets the all inhouse parameters likes; active ingredients content, pH range, dustiness, dry sieve, attrition resistance, bulk density and moisture content, in laboratory condition (for 14 days) and room temperature (up to 12 months).

Manufacturing process for preparing 100 kg composition of Emamectin benzoate 0.16%+Chlorantraniliprole 0.4%+Clothianidin 0.8% Granule
Step 1-Add 0.16 kg of Emamectin Benzoate and 0.40 kg of Chlorantraniliprole technical into 3.0 kg of N-methyl-2-pyrrolidone, 0.5 kg of Rhodamine dye and add 3.0 kg of Tri-styryl Phenol Ethoxylate, 1.0 kg of Copolymer of propylene oxide (PO) and ethylene oxide (EO) and then add 2.0 kg of polyvinyl alcohols and homogenize the mixture.
Step 2-Now spray this mixture on 86.64 kg of River sand granules and blend it till homogeneity
Step 3-Add 2.5 kg of nano polysaccharide onto these granules and blend it till homogeneity.
Step 4- Now blend 0.8 kg of Clothianidin technical and then 1.0 kg of precipitated silica and homogenize it till homogeneity.
Step 5- Finally add silica to make granules free flowing and free of moisture
Step 6- Final product is sent for QC approval.
Step 8- After approval, material is packed in required pack sizes.

Example 4: Composition of Emamectin benzoate 0.15% + Cyantraniliprole 0.5% + Clothianidin 0.5% Granule
Ingredients content % (w/w) Function
Emamectin Benzoate a.i. 0.15 active ingredient 1
Cyantraniliprole a.i. 0.50 active ingredient 2
Clothianidin a.i. 0.50 active ingredient 3
Tri-styryl Phenol Ethoxylate 3.00 Emulsifier
Polyvinyl alcohols 2.00 controlled release agent-1
Nano polysaccharide 2.50 inert 1
N-methyl-2-pyrrolidone 3.00 Solvent
Copolymer of propylene oxide (PO) and ethylene oxide (EO) 1.00 dispersing agent
Paraffin wax 5.00 controlled release agent-2
Rhodamine 0.50 Colourant
Precipitated silica 1.00 inert 2
Riversand (Silica) 80.85 carrier/filler
Total 100.00
a.i.-active ingredient on 100% purity basis

Storage stability- Emamectin benzoate 0.15% + Cyantraniliprole 0.5% + Clothianidin 0.5% Granule
Laboratory storage stability
Parameters Specification (in house) Initial at 54±2 0C at 0±2 0C
Emamectin Benzoate a.i. 0.1425 to 0.165 0.16 0.155 0.16
Cyantraniliprole a.i. 0.475 to 0.55 0.55 0.52 0.55
Clothianidin a.i. 0.475 to 0.55 0.55 0.53 0.55
pH range (1% aq. Suspension) 4.0 to 7.0 5.50 5.50 5.50
Dustiness < 20 mg 10 10 10
Dry sieve (300 micron) percent by mass min. > 90% 99.5 99.2 99.3
Attrition Resistance (<100 micron) < 5% 2.10 2.10 2.10
Bulk density (g/ml) 1.25 to 1.50 1.35 1.35 1.35
Moisture content percent by mass max. max. 2% 1.50 1.50 1.50
Room temperature storage stability
Parameters specification (in house) 1 month 6 months 12 months
Emamectin Benzoate a.i. 0.285 to 0.330 0.16 0.16 0.155
Cyantraniliprole a.i. 50 to 150 0.55 0.55 0.54
Clothianidin a.i. 3.80 to 4.40 0.55 0.55 0.54
pH range (1% aq. Suspension) 4.0 to 7.0 5.50 5.50 5.50
Dustiness < 20 mg 10 10 10
Dry sieve (300 micron) percent by mass min. > 90% 99.50 96.35 96.25
Attrition Resistance (<100 micron) < 5% 2.10 2.10 2.10
Bulk density (g/ml) 1.25 to 1.50 1.35 1.35 1.35
Moisture content percent by mass max. max. 2% 1.50 1.50 1.40

The storage stability study of composition of Emamectin benzoate 0.15%+Cyantraniliprole 0.5%+Clothianidin 0.5% Granule (Controlled release granule) meets the all inhouse parameters likes; active ingredients content, pH range, dustiness, dry sieve, attrition resistance, bulk density and moisture content, in laboratory condition (for 14 days) and room temperature (up to 12 months).

Manufacturing process for preparing 100 kg composition of Emamectin benzoate 0.15%+Cyantraniliprole 0.5%+Clothianidin 0.5% Granule
Step 1-Add 0.15 kg of Emamectin Benzoate and 0.5 kg of Cyantraniliprole technical into 3.0 kg of N-methyl-2-pyrrolidone, 0.5 kg of Rhodamine dye and add 3.0 kg of Tri-styryl Phenol Ethoxylate then add 2.0 kg of polyvinyl alcohols and homogenize the mixture.
Step 2-Now spray this mixture on 80.85 kg of River sand granules and blend it till homogeneity
Step 3-Add 2.5 kg of nano polysaccharide onto these granules and blend it till homogeneity.
Step 4-Now mix 1.0 kg of Copolymer of propylene oxide (PO) and ethylene oxide (EO) and 5.0 kg of Paraffin wax and blend it on these treated granules and homogenize.
Step 5- Now blend 0.5 kg of Clothianidin technical and then 1.0 kg of precipitated silica and homogenize it till homogeneity
Step 5- Finally add silica to make granules free flowing and free of moisture
Step 6- Final product is sent for QC approval.
Step 8- After approval, material is packed in required pack sizes.

Example 5: Composition of Emamectin benzoate 0.15% + Cyantraniliprole 0.5% + Flupyrimin 0.75% Granule
Ingredients Content % (w/w) Function
Emamectin Benzoate a.i. 0.15 active ingredient 1
Cyantraniliprole a.i. 0.50 active ingredient 2
Flupyrimin a.i. 0.75 active ingredient 3
Polyacrylic acid 0.40 controlled release agent
Water 0.40 Solvent
Dodecyl hydroxypoly (oxy-1,2 ethanediyl) phosphate 0.40 Emulsifier
Calcium lignosulfonate 1.00 Dispersing agent
Dye blue 0.05 Colourant
Talc powder 8.00 inert
Sand 88.35 carrier/filler
Total 11.65
a.i.-active ingredient on 100% purity basis

The storage stability study of composition of Emamectin benzoate 0.15%+Cyantraniliprole 0.5%+Flupyrimin 0.75% Granule meets the all inhouse parameters likes; active ingredients content, pH range, dustiness, dry sieve, attrition resistance, bulk density and moisture content, in laboratory condition (for 14 days) and room temperature (up to 12 months).
Example 6: Composition of Emamectin benzoate 2% + Cyantraniliprole 10% + Flupyrimin 16% Granule
Chemical composition Percent (w/w) Function
Emamectin benzoate a.i. 2.00 Active ingr. 1
Cyantraniliprole a.i. 10.00 Active ingr. 1
Flupyrimin a.i. 16.00 Active ingr. 1
Polyalkyleneoxide modified heptamethyltrisiloxane 3.00 Wetting agent
Alkyl naphthalene sulfonate-sodium salt 3.00 Dispersing agent
Sodium lignosulfonate 30.00 Dispersing agent
Polydimethyl siloxane 0.50 Antifoaming agent
Sodium sulphate anhydrous 6.00 Humectant
Urea formaldehyde resin 5.00 carrier
China Clay 24.50 Carrier
Total 100.00
a.i.-active ingredient on 100% purity basis.

Storage stability-Emamectin benzoate 2%+Cyantraniliprole 10%+Flupyrimin 16% Granule
Laboratory storage stability for 14 days
Parameters specification (in house) Initial At 54±2 0C At 0±2 0C
Emamectin benzoate a.i. 1.90 to 2.20 2.25 2.15 2.25
Cyantraniliprole a.i. 9.50 to 10.50 10.40 10.25 10.40
Flupyrimin a.i 15.20 to 16.80 16.50 16.20 16.40
Emamectin benzoate suspensibility (%) 70 98.5 98 98.2
Cyantraniliprole suspensibility (%) 70 99.5 99.2 99.4
Flupyrimin suspensibility (%) 70 98.7 98.3 98.6
pH range (1% aq. Suspension) 6 to 8.5 7.2 7.3 7.2
wettability sec. max. Max 30 sec 5 6 5
wet sieve (45 micron) percent by mass min. mini 99.0% 99.5 99.4 99.5
bulk density (g/ml) 0.35 to 0.55 0.45 0.45 0.45
moisture content percent by mass max. max. 3% 1 1 1.1
Room temperature storage stability up to 12 months
Parameters Specification (in house) 1 month 6 months 12 months
Emamectin benzoate a.i. 1.90 to 2.20 2.25 2.25 2.23
Cyantraniliprole a.i. 9.50 to 10.50 10.40 10.40 10.38
Flupyrimin a.i 15.20 to 16.80 16.50 16.50 16.40
Emamectin benzoate suspensibility (%) 70 98.5 98.5 98.2
Cyantraniliprole suspensibility (%) 70 99.5 99.5 99.4
Flupyrimin suspensibility (%) 70 98.7 98.7 98.6
pH range (1% aq. Suspension) 6 to 8.5 7.2 7.2 7.25
wettability sec. max. Max 30 sec 5 5 6
wet sieve (45 micron) percent by mass min. mini 99.0% 99.5 99.4 99.5
bulk density (g/ml) 0.35 to 0.55 0.45 0.45 0.45
moisture content percent by mass max. max. 3% 1 1 1
The storage stability study of composition of Emamectin benzoate 2%+Cyantraniliprole 10%+Flupyrimin 16% Granule meets the all inhouse parameters likes; active ingredients content, suspensibility (%), pH range, wettability, wet sieve, bulk density and moisture content in laboratory condition (for 14 days) and room temperature (up to 12 months).
Manufacturing process for preparing 100 kg composition of Emamectin benzoate 2%+Cyantraniliprole 10%+Flupyrimin 16% Granule
Step 1-Take 70 kg water and add 3.0 kg of Alkyl naphthalene sulfonate-sodium salt, 30.0 kg of Sodium lignosulfonate and 0.50 kg of Polydimethyl siloxane into a vessel having high speed homogenizer.
Step 2-Add 2.0 kg of Emamectin Benzoate technical, 10 kg of Cyantraniliprole technical, 16.0 kg of Flupyrimin technical; and homogenize using high shear homogenizer for 30-45 minutes.
Step 3-Now add 6.0 kg of Sodium Sulfate anhydrous, 5.0 kg of Urea formaldehye resin and 24.50 kg of China clay, 3.0 kg of Polyalkyleneoxide modified heptamethyltrisiloxane and homogenize using high shear homogenizer for 30-45 minutes.
Step 4-Mill this premix using Sand mill untill D90 is less than 10 microns.
Step 5-Now spray this slurry in spray dryer at specific temperature (inlet temperature below 150 C degree and outer temperature less than 85 C degree) to get granules from range o f 0.1 to 50 microns and remove excess 70 kg water.
Step 6-Finally send samples to QC for quality check.

Biological Examples:
The granular compositions of emamectin benzoate+diamide insecticide+insecticide has been developed in the laboratory and evaluated under field condition in terms of bio-efficacy, residual control and compared with conventional combinations and tank mixes.
A synergistic effect exists wherever the action of a combination of active ingredient is greater than the sum of the action of each of the components alone. Therefore, a synergistically effective amount or an effective amount of a synergistic composition or combination is an amount that exhibits greater pesticidal activity than the sum of the pesticidal activities of the individual components.
In the field of agriculture, it is often understood that the term “synergy” is as defined by Colby S.R. in an article entitled “ Calculation of the synergistic and antagonistic responses of herbicide combinations” published in the journal Weeds, 1967, 15, p.20-22, incorporated herein by reference in its entirety. The action expected for a given combination of two or three active components can be calculated as follows:

Experiment 1: Bioefficacy of granular composition of Emamectin benzoate+Chlorantraniliprole+Insecticide on insect-pests control and yield attributing characters in rice crop
Crop : Rice
Location : Dhamtari, Chattishgarh
Number of Treatments: Twenty four
Replication : Two
Method of Application: Soil application-manual broadcasting at 22 DATP (Days after transplanting)
Observation Methods:
Stem borer control (%): Stem borer (Scirpophaga incertulas) causes damage as dead heart (damaged tiller) symptoms in vegetative growth stage and white ear (tillers with damaged ear head/panicles) symptoms in reproductive stage.
Dead heart symptoms: Count the number of healthy and damaged tillers (dead heart) per hill. Record the observations from 10 hills per plot at 50 DATP (days after transplanting). Calculate Dead Heart (%) incidence and recalculate stem borer(%) control.
White ear symptoms: Count the number of tillers with healthy earhead and white ear per hill. Record the observations from 10 hills per plot at 100 DATP. Calculate white ear incidence (%) and recalculate stem borer control (%).




Leaf folder (Cnaphalocrocis medinalis) control (%): Count the number of damaged leaflet and healthy leaflet per hill. Record the observations from 10 hills per plot at 40 DATP. Calculate Leaf folder damage (%).


Brown Plant Hopper (BPH, Nilaparvata lugens) Control (%): Count the number of live BPH (nymph+adult stage) per hill. Record the observations from 10 hills per plot at 75 DATP. Calculate BPH control (%).

Productive Tillers Count: Count the number of productive tillers per hill. Record the observations from 20 hills per plot.
Table 1: Treatment details
Treatment number Treatment details Formulation (g or ml) per hectare gram active ingredients per hectare
T1 Emamectin benzoate 0.16%+Chlorantraniliprole 0.32%+Clothianidin 0.8% Granule 7500 12+24+60
T2 Emamectin benzoate 0.16%+Chlorantraniliprole 0.32%+Thiamethoxam 0.8% Granule 7500 12+24+60
T3 Emamectin benzoate 0.16%+Chlorantraniliprole 0.32%+Imidacloprid 0.5% Granule 7500 12+24+37.5
T4 Emamectin benzoate 0.16%+Chlorantraniliprole 0.32%+Triflumezopyrim 0.24% Granule 7500 12+24+18
T5 Emamectin benzoate 0.16%+Chlorantraniliprole 0.32%+Flupyrimin 1% Granule 7500 12+24+75
T6 Chlorantraniliprole 0.32%+Clothianidin 0.8% Granule 7500 24+60
T7 Chlorantraniliprole 0.32%+Thiamethoxam 0.8% Granule 7500 24+60
T8 Chlorantraniliprole 0.32%+Imidacloprid 0.5% Granule 7500 24+37.5
T9 Chlorantraniliprole 0.32%+Triflumezopyrim 0.24% Granule 7500 24+18
T10 Chlorantraniliprole 0.32%+Flupyrimin 1% Granule 7500 24+75
T11 Emamectin benzoate 0.16%+Clothianidin 0.8% Granule 7500 12+60
T12 Emamectin benzoate 0.16%+Thiamethoxam 0.8% Granule 7500 12+60
T13 Emamectin benzoate 0.16%+Imidacloprid 0.5% Granule 7500 12+37.5
T14 Emamectin benzoate 0.16%+Triflumezopyrim 0.24% Granule 7500 12+18
T15 Emamectin benzoate 0.16%+Flupyrimin 1% Granule 7500 12+75
T16 Emamectin benzoate 0.16%+Chlorantraniliprole 0.32% Granule 7500 12+24
T17 Emamectin benzoate 5% SG 240 12
T18 Chlorantraniliprole 0.4% GR 6000 24
T19 Clothianidin 0.5% GR 12000 60
T20 Thiamethoxam 25% WG 240 60
T21 Imidacloprid 0.3% GR 12500 37.5
T22 Triflumezopyrim 10.6% SC 169.8 18
T23 Flupyrimin 2% GR 3750 75
T24 UTC (Untreated Control) - -

T1 to T5-ready mix granular compositions, T6 to T23-conventional treatments. SG-soluble granule, WG-Wettable Granule, SC-Suspension concentrate, T17, T20, T22- mixed with sand and broadcasted manually

Table 2: Control of stem borer in rice crop
Treatment number Stem borer control (%)
Dead heart symptoms White ear symptoms
Observed Expected Colby's ratio Synergism (Y/N) Observed Expected Colby's ratio Synergism (Y/N)
T1 100.0 91.28 1.10 Y 83.8 72.34 1.16 Y
T2 100.0 92.50 1.08 Y 80.7 73.33 1.10 Y
T3 100.0 90.44 1.11 Y 74.7 70.31 1.06 Y
T4 100.0 93.68 1.07 Y 90.3 77.02 1.17 Y
T5 100.0 94.58 1.06 Y 95.8 82.33 1.16 Y
T6 82.5 80.09 1.03 Y 57.2 59.02 0.97 N
T7 80.4 78.96 1.02 Y 54.8 57.79 0.95 N
T8 79.0 78.17 1.01 Y 52.5 56.02 0.94 N
T9 86.4 85.57 1.01 Y 61.5 65.95 0.93 N
T10 95.7 87.62 1.09 Y 77.4 73.83 1.05 N
T11 72.8 72.32 1.01 Y 40.2 43.77 0.92 N
T12 71.3 70.74 1.01 Y 39.7 42.09 0.94 N
T13 70.2 69.65 1.01 Y 35.3 39.66 0.89 N
T14 80.6 79.94 1.01 Y 50.2 53.29 0.94 N
T15 87.2 82.79 1.05 Y 63.8 64.09 1.00 N
T16 88.5 86.20 1.03 Y 65.4 66.79 0.98 N
T17 56.2 32.5
T18 68.5 50.8
T19 36.8 16.7
T20 33.2 14.2
T21 30.7 10.6
T22 54.2 30.8
T23 60.7 46.8
T24 0.0 0.0

The granular composition of emamectin benzoate +Chlorantraniliprole +insecticide (T1 to T5) provides synergistic residual control of stem borer as compared to all conventional treatments.
Table 3: Control of Leaf folder, Brown Plant Hopper in rice
Treatment number Leaf folder control (%) BPH control (%) Productive tillers per sq.m. Increase over T24

T1 100.0 82.80 280.30 68.7
T2 100.0 81.30 276.40 66.3
T3 100.0 80.30 271.70 63.5
T4 100.0 88.40 282.70 70.1
T5 100.0 85.70 286.50 72.4
T6 79.20 62.30 248.70 49.6
T7 79.00 61.80 240.60 44.8
T8 78.80 60.70 230.80 38.9
T9 79.30 70.30 253.20 52.3
T10 95.70 66.30 258.50 55.5
T11 61.30 62.90 226.40 36.2
T12 61.00 62.40 220.80 32.9
T13 60.80 61.50 213.50 28.5
T14 61.70 69.50 231.50 39.3
T15 90.70 66.20 238.50 43.5
T16 89.20 21.60 235.80 41.9
T17 60.50 10.40 192.50 15.8
T18 78.50 8.50 198.60 19.5
T19 20.70 60.90 191.70 15.3
T20 18.20 58.40 186.40 12.2
T21 15.60 54.20 180.30 8.5
T22 22.60 68.50 200.30 20.5
T23 72.60 65.30 202.60 21.9
T24 0.00 0.00 166.20 0.0

The granular composition of emamectin benzoate + Chlorantraniliprole + insecticide (T1 to T5) provides excellent control of leaf folder and brown plant hopper and also bears higher number of productive tillers compared to all conventional treatments (T6 to T23).

Experiment 2: Bioefficacy of granular composition of Emamectin benzoate+Chlorantraniliprole+ Insecticide against rice stem borer.
Crop : Rice
Location : Rudrapur, Uttarakhand
Number of Treatments: Twenty six
Replication : Two
Method of Application: Soil application-manual broadcasting at 28 DATP (Days after transplanting)
Observation Methods:
Stem borer control (%): as given in experiment 1.
Table 4: Treatment details
Treatment number Treatment details Formulation (g) per hectare gram active ingredients per hectare
T1 Emamectin benzoate 0.15%+Chlorantraniliprole 0.25%+Dichloromezotiaz 0.5% Granule 10000 15+25+50
T2 Emamectin benzoate 0.12%+Chlorantraniliprole 0.2%+Cartap hydrochloride 4% Granule 12500 15+25+500
T3 Emamectin benzoate 0.12%+Chlorantraniliprole 0.2%+Thiocyclam hydrogen oxalate 4% Granule 12500 15+25+500
T4 Emamectin benzoate 0.3%+Chlorantraniliprole 0.5%+Fipronil 1% Granule 5000 15+25+50
T5 Emamectin benzoate 0.3%+Chlorantraniliprole 0.5%+Spinetoram 1% Granule 5000 15+25+50
T6 Chlorantraniliprole 0.25%+Dichloromezotiaz 0.5% Granule 10000 25+50
T7 Chlorantraniliprole 0.2%+Cartap hydrochloride 4% Granule 12500 25+500
T8 Chlorantraniliprole 0.2%+Thiocyclam hydrogen oxalate 4% Granule 12500 25+500
T9 Chlorantraniliprole 0.5%+Fipronil 1% Granule 5000 25+50
T10 Chlorantraniliprole 0.5%+Spinetoram 1% Granule 5000 25+50
T11 Emamectin benzoate 0.15%+Dichloromezotiaz 0.5% Granule 10000 15+50
T12 Emamectin benzoate 0.12%+Cartap hydrochloride 4% Granule 12500 15+500
T13 Emamectin benzoate 0.12%+Thiocyclam hydrogen oxalate 4% Granule 12500 15+500
T14 Emamectin benzoate 0.3%+Fipronil 1% Granule 5000 15+50
T15 Emamectin benzoate 0.3%+Spinetoram 1% Granule 5000 15+50
T16 Emamectin benzoate 0.15%+Chlorantraniliprole 0.25% Granule 10000 15+25
T17 Emamectin benzoate 5% SG 300 15
T18 Chlorantraniliprole 0.4% GR 6250 25
T19 Dichloromezotiaz 35% WG 142.9 50
T20 Cartap hydrochloride 4% GR 12500 500
T21 Thiocyclam hydrogen oxalate 4% GR 12500 500
T22 Fipronil 0.3% GR 16667 50
T23 Spinetoram 0.8% GR 6250 50
T24 Emamectin benzoate 0.25 %+Cartap Hydrochloride 7.5 % GR 7500 18.75+562.5
T25 Fipronil 0.5%+Cartap Hydrochloride 4% CG 20000 100+800
T26 UTC (Untreated Control) - -
T1 to T5- ready mix granular composition; T6 to T25-conventional treatments; T17, T19-mixed with sand and broadcasted manually.
Table 5: Stem borer control
Treatment number Stem borer control (%)
Dead heart symptoms White ear symptoms
Observed Expected Colby's ratio Synergism (Y/N) Observed Expected Colby's ratio Synergism (Y/N)
T1 100.0 95.16 1.05 Y 95.3 81.59 1.17 Y
T2 100.0 94.55 1.06 Y 96.5 81.64 1.18 Y
T3 100.0 96.13 1.04 Y 97.3 83.22 1.17 Y
T4 100.0 95.20 1.05 Y 92.8 81.25 1.14 Y
T5 100.0 94.97 1.05 Y 93.6 80.48 1.16 Y
T6 90.3 88.29 1.02 Y 70.2 71.76 0.98 N
T7 91.3 90.06 1.01 Y 71.6 73.37 0.98 N
T8 91.5 90.62 1.01 Y 72.7 74.27 0.98 N
T9 89.7 88.38 1.01 Y 70.2 71.24 0.99 N
T10 88.5 87.82 1.01 Y 68.5 70.06 0.98 N
T11 84.5 83.60 1.01 Y 60.3 61.08 0.99 N
T12 87.3 86.08 1.01 Y 62.7 63.29 0.99 N
T13 88.2 86.87 1.02 Y 63.8 64.53 0.99 N
T14 84.7 83.73 1.01 Y 59.2 60.36 0.98 N
T15 83.8 82.94 1.01 Y 57.5 58.73 0.98 N
T16 88.5 87.82 1.01 Y 67.3 69.16 0.97 N
T17 58.7 34.8
T18 70.5 52.7
T19 60.3 40.3
T20 66.3 43.7
T21 68.2 45.6
T22 60.6 39.2
T23 58.7 36.7
T24 87.5 66.5
T25 80.3 60.3
T26 0.0 0.0

The ready mix granular composition of emamectin benzoate + Chlorantraniliprole + insecticide (T1 to T5) provides synergistic residual control of rice stem borer compared to all conventional treatments (T6 to T26).

Experiment 3: Bioefficacy of granular composition of Emamectin benzoate +Cyantraniliprole+ Insecticide against rice stem borer.
Crop : Rice
Location : Kurud, Chhattishgarh
Number of Treatments: Twenty six
Replication : Two
Method of Application: Soil application-manual broadcasting at 35 DATP (Days after transplanting)
Observation Methods: as per the experiment 1.
Table 6: Treatment details
Treatment number Treatment details Formulation (kg) per hectare gram active ingredients per hectare
T1 Emamectin benzoate 0.15%+Cyantraniliprole 0.5%+Fipronil 0.5% Granule 10000 15+50+50=115
T2 Emamectin benzoate 0.15%+Cyantraniliprole 0.5%+Clothianidin 0.5% Granule 10000 15+50+50=115
T3 Emamectin benzoate 0.15%+Cyantraniliprole 0.5%+Triflumezopyrim 0.2% Granule 10000 15+50+20=85
T4 Emamectin benzoate 0.15%+Cyantraniliprole 0.5%+Flupyrimin 0.75% Granule 10000 15+50+75=140
T5 Emamectin benzoate 0.15%+Cyantraniliprole 0.5%+Cartap hydrochloride 4% Granule 10000 15+50+400=465
T6 Emamectin benzoate 0.15%+Cyantraniliprole 0.5%+Thiocyclam hydrogen oxalate 4% Granule 10000 15+50+400=465
T7 Emamectin benzoate 5% SG 300 15
T8 Cyantraniliprole 0.4% GR 12500 50
T9 Fipronil 0.3% GR 16666.7 50
T10 Clothianidin 0.5% GR 10000 50
T11 Triflumezopyrim 10.6% SC 188.7 20
T12 Flupyrimin 2% GR 3750 75
T13 Cartap hydrochloride 4% GR 12500 500
T14 Thiocyclam hydrogen oxalate 4% GR 12500 500
T15 Cyantraniliprole 0.5%+Fipronil 0.5% Granule 12500 62.5+62.5=125
T16 Cyantraniliprole 20%+Clothianidin 20% SC 300 60+60=120
T17 Cyantraniliprole 10%+Triflumezopyrim 4% SC 600 60+24=84
T18 Cyantraniliprole 6%+Flupyrimin 10% SC 1000 60+100=160
T19 Cyantraniliprole 0.5%+Cartap hydrochloride 4% Granule 12500 62.5+500=562.5
T20 Cyantraniliprole 0.5%+Thiocyclam hydrogen oxalate 4% Granule 12500 62.5+500=562.5
T21 Emamectin benzoate 1.5%+Fipronil 3.5% SC 1500 22.5+52.5=75
T22 Emamectin benzoate 0.25 %+Cartap Hydrochloride 7.5 % GR 7500 18.75+562.5=581.25
T23 Emamectin benzoate 0.25%+Thiocyclam hydrogen oxalate 7.5% Granule 7500 18.75+562.5=581.25
T24 Emamectin benzoate 2%+Cyantraniliprole 5% SC 1000 20+50=70
T25 Fipronil 0.5%+Cartap Hydrochloride 4% CG 20000 100+800=900
T26 UTC (Untreated Control) - -
T1 to T6- ready mix granular composition, T7 to T25-conventional treatments

Table 7: Control of rice stem borer and leaffolder
Treatment number Stem borer control (%) Leaf folder control (%)
Observed Expected Colby's ratio Synergism (Y/N)
T1 100.0 95.80 1.04 Y 100.0
T2 99.2 75.53 1.31 Y 100.0
T3 100.0 95.49 1.05 Y 100.0
T4 100.0 95.83 1.04 Y 100.0
T5 100.0 96.50 1.04 Y 100.0
T6 100.0 96.68 1.03 Y 100.0
T7 60.3 66.80
T8 72.6 75.30
T9 61.4 65.20
T10 34.6 22.80
T11 58.5 30.40
T12 61.7 68.50
T13 67.8 71.30
T14 69.5 73.80
T15 84.2 89.50
T16 83.5 82.40
T17 85.2 85.60
T18 88.3 88.20
T19 85.3 89.50
T20 86.7 90.80
T21 81.4 83.40
T22 86.2 85.60
T23 85.6 87.20
T24 88.2 88.40
T25 78.6 84.6
T26 0.0 0.00

The granular composition of emamectin benzoate+cyantraniliprole+insecticide (T1 to T6) provides synergistic control of rice stem borer and leaf folder compared to all conventional treatments (T7 to T25).
Table 8: Control rice BPH and productive tillers
Treatment number BPH control (%) Productive tillers per sq.m. Increase over T30

T1 84.7 290.3 64.2
T2 100.0 291.6 64.9
T3 100.0 293.5 66.0
T4 100.0 296.4 67.6
T5 88.8 284.5 60.9
T6 85.2 286.6 62.1
T7 12.8 218.8 23.8
T8 24.6 234.8 32.8
T9 19.5 224.6 27.0
T10 65.4 230.7 30.5
T11 70.7 231.6 31.0
T12 62.4 245.6 38.9
T13 38.6 216.7 22.6
T14 40.6 220.3 24.6
T15 74.5 261.3 47.8
T16 80.2 265.6 50.2
T17 81.8 268.4 51.8
T18 82.6 273.4 54.6
T19 74.2 264.3 49.5
T20 75.8 267.8 51.5
T21 71.3 253.4 43.3
T22 70.4 257.6 45.7
T23 72.4 255.4 44.5
T24 77.8 260.5 47.3
T25 65.3 246.8 39.6
T26 0.0 176.8 0.0

The granular composition of emamectin benzoate+cyantraniliprole+insecticide (T1 to T6) provides excellent control of Rice BPH and also produces higher number of productive tillers compared to all conventional treatments (T7 to T25).

Experiment 4: Bioefficacy of granular composition of Emamectin benzoate+tetraniliprole+insecticide against sugarcane shoot borer
Crop : Sugarcane
Location : Karnal, Haryana
Plot size : 50 sq.m.
Number of Treatments: Twenty three
Replication : Two
Method of Application: At the time of cane planting, the required quantity of novel granular composition broadcasted manually in the open furrow over the sugarcane setts then covered with soil.
Observation Methods:
Early shoot borer (Chilo infuscatellus) incidence (%):
Fifty shoots per plot were selected randomly and presence of characteristic “dead heart” (damaged shoots) were recorded to calculate per cent shoot damage by early shoot borer at 45 (DAP) days after planting.

Early shoot borer (ESB) control calculated by below formula,

Early shoot borer control (%) data used to check the synergism by applying Colby’s formula given above.
Shoot count: Count the number of shoots/tillers from 1 mrl (meter row length) from randomly selected 5 spot per plot at 60 days after planting.
The percent increase in shoot over untreated control were calculated by below formula.

Table 9: Treatment details
Treatment number Treatment details Formulation (g or ml) per hectare gram active ingredients per hectare
T1 Emamectin benzoate 0.3%+Tetraniliprole 0.6+Clothianidin 1% Granule 6000 18+36+60=114
T2 Emamectin benzoate 0.3%+Tetraniliprole 0.6%+Thiamethoxam 1% Granule 6000 18+36+60=114
T3 Emamectin benzoate 0.3%+Tetraniliprole 0.6%+Triflumezopyrim 0.5% Granule 6000 18+36+30=84
T4 Emamectin benzoate 0.3%+Tetraniliprole 0.6%+Flupyrimin 1.5% Granule 6000 18+36+90=144
T5 Emamectin benzoate 0.3%+Tetraniliprole 0.6%+Fipronil 1% Granule 6000 18+36+60=114
T6 Emamectin benzoate 0.15%+Tetraniliprole 0.3%+Cartap hydrochloride 4% Granule 12000 18+36+480=534
T7 Tetraniliprole 0.6%+Clothianidin 1% Granule 7500 45+75=120
T8 Tetraniliprole 0.6%+Thiamethoxam 1% Granule 7500 45+75=120
T9 Tetraniliprole 0.6%+Triflumezopyrim 0.5% Granule 7500 45+37.5=82.5
T10 Tetraniliprole 0.6%+Flupyrimin 1.5% Granule 7500 45+112.5=157.5
T11 Tetraniliprole 0.6%+Fipronil 1% Granule 7500 45+75=120
T12 Tetraniliprole 0.6%+Cartap hydrochloride 4% Granule 15000 45+600=645
T13 Emamectin benzoate 5% SG 360 18
T14 Tetraniliprole 0.4% GR 9000 36
T15 Clothianidin 0.5% GR 12000 60
T16 Thiamethoxam 25% WG 240 60
T17 Triflumezopyrim 10.6% SC 283 30
T18 Flupyrimin 2% GR 4500 90
T19 Fipronil 0.6% GR 10000 60
T20 Cartap hydrochloride 4% GR 12000 480
T21 Emamectin benzoate 0.25 %+Cartap Hydrochloride 7.5 % GR 7500 18.75+562.5
T22 Fipronil 0.5%+Cartap Hydrochloride 4% CG 20000 100+800
T23 UTC (Untreated Control) - -
T1 to T6- ready mix granular composition, T7 to T22-conventional treatments
Table 10: Early shoot borer control in sugarcane
Treatment number Early shoot borer control (%) Number of shoots per mrl Increase over T23
Control Observed Control Expected Colby's ratio
T1 100.0 92.65 1.08 82.7 116.5
T2 97.5 87.74 1.11 80.5 110.7
T3 98.7 93.09 1.06 81.3 112.8
T4 100.0 94.04 1.06 80.7 111.3
T5 100.0 94.64 1.06 83.8 119.4
T6 99.8 93.79 1.06 78.5 105.5
T7 85.4 71.2 86.4
T8 84.8 68.1 78.3
T9 86.3 70.6 84.8
T10 88.7 69.5 81.9
T11 90.2 72.7 90.3
T12 88.6 67.4 76.4
T13 51.2 54.5 42.7
T14 70.7 61.5 61.0
T15 48.6 60.7 58.9
T16 45.4 56.3 47.4
T17 51.7 54.6 42.9
T18 58.3 56.4 47.6
T19 62.5 59.3 55.2
T20 56.6 49.8 30.4
T21 70.6 63.2 65.4
T22 75.4 68.4 79.1
T23 0.0 38.2 0.0

The granular composition of emamectin benzoate+tetraniliprole+insecticide (T1 to T6) provides synergistic control of sugarcane early shoot borer also produces higher number of productive shoots compared to all conventional treatments (T7 to T22).

Experiment 5: Bioefficacy of granular composition against insect-pests of rice
Crop : Rice
Location : Sambhalpur, Orrisa
Number of Treatments: 19
Replication : 2
Method of Application: Soil application-manual broadcasting at 32 DATP (Days after transplanting). The required quantity of treatments T1 to T6 were further dissolved in water and mixed it with sand to bulk it out and broadcasted manually in the plot.
Observation Methods: as given in experiment 1.
Table 11: Treatment details
Treatment number Treatment details Formulation (g or ml) per hectare gram active ingredients per hectare
T1 Emamectin benzoate 2%+Chlorantraniliprole 5%+Flupyrimin 16% Granule 500 10+25+80
T2 Emamectin benzoate 2%+Cyantraniliprole 10%+Flupyrimin 16% Granule 500 10+50+80
T3 Emamectin benzoate 2%+Tetraniliprole 6%+Flupyrimin 16% Granule 500 10+30+80
T4 Emamectin benzoate 10%+Chlorantraniliprole 25%+Triflumezopyrim 20% Granule 100 10+25+20
T5 Emamectin benzoate 5%+Cyantraniliprole 25%+Triflumezopyrim 10% Granule 200 10+50+20
T6 Emamectin benzoate 5%+Tetraniliprole 18%+Triflumezopyrim 10% Granule 200 10+30+20
T7 Chlorantraniliprole 5%+Flupyrimin 16% SC 500 25+80
T8 Cyantraniliprole 10%+Flupyrimin 16% SC 500 50+80
T9 Tetraniliprole 6%+Flupyrimin 16% SC 500 30+80
T10 Chlorantraniliprole 12.5%+Triflumezopyrim 10% SC 200 25+20
T11 Cyantraniliprole 12.5%+Triflumezopyrim 5% SC 400 50+20
T12 Tetraniliprole 18%+Triflumezopyrim 10% SC 200 30+20
T13 Emamectin benzoate 5% SG 200 10
T14 Chlorantraniliprole 18.5% w/w (20% w/v SC) 125 25
T15 Cyantraniliprole 18.41% w/w (20% w/v SC) 250 50
T16 Tetraniliprole 18.18% w/w (20% w/v SC) 150 30
T17 Flupyrimin 10% SC 800 80
T18 Triflumezopyrim 10.6% SC 188.7 20
T19 UTC (Untreated Control) - -
T1 to T6-ready mix granular composition; T7 to T18-conventional treatments

Table 12: Control of insect-pests of rice crop
Treatment number Stem borer incidence (%) Leaf folder incidence (%) Number of BPH per hill Number of Effective tillers per sq.m. Increase over T19
Dead heart symptoms White earhead symptoms
35 DATP 95 DATP 55 DATP 50 DATP 80 DATP
T1 0.0 0.00 0.00 0.00 1.73 317.3 42.7
T2 0.0 0.00 0.00 0.00 1.28 312.4 40.5
T3 0.0 0.00 0.00 0.00 1.56 310.5 39.6
T4 0.0 0.16 0.00 0.00 1.06 316.2 42.2
T5 0.0 0.28 0.00 0.00 0.82 318.7 43.3
T6 0.0 0.21 0.00 0.00 0.97 311.7 40.2
T7 0.24 1.16 0.72 0.00 6.15 273.9 23.2
T8 0.35 1.48 0.96 0.00 5.27 275.3 23.8
T9 0.28 1.28 0.83 0.00 5.83 272.2 22.4
T10 0.47 1.88 1.04 0.00 4.12 274.8 23.6
T11 0.63 2.11 1.28 0.00 3.68 276.8 24.5
T12 0.52 1.96 1.15 0.00 3.97 274.2 23.3
T13 1.72 2.96 2.46 2.86 18.48 247.4 11.2
T14 1.10 2.47 1.87 4.28 21.86 251.6 13.1
T15 1.32 2.82 2.07 3.82 16.26 257.7 15.9
T16 1.18 2.58 1.92 4.94 17.23 250.4 12.6
T17 1.36 2.74 2.85 0.64 8.46 258.4 16.2
T18 1.86 3.12 4.16 0.27 7.95 255.2 14.7
T19 2.85 7.68 14.86 6.84 32.95 222.4 0.0

All the ready mix granular compositions (T1 to T6) provides excellent, season long control of rice stem borer, leaf folder and rice BPH and also produces higher number of effective (productive) tillers as compared to conventional treatments (T7 to T18).
,CLAIMS:CLAIMS
We claim;

[CLAIM 1]. A synergistic granular agrochemical composition comprising:
a. emamectin benzoate in an amount of 0.01% to 5% by weight;
b. an insecticide from diamide group present in an amount of 0.1 % - 20 % by weight;
c. an insecticide selected from group of phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, nereis toxin or mixture thereof present in an amount of 1-20% by weight.
d. formulation excipients

[CLAIM 2]. The synergistic granular agrochemical composition as claimed in claim 1, wherein an insecticide from diamide group is selected from chlorantraniliprole, cyantraniliprole, cyclaniliprole, tetraniliprole, tetrachlorantraniliprole, tyclopyrazoflor, cyhalodiamide, flubendiamide, fluchlordiniliprole.

[CLAIM 3]. The synergistic granular agrochemical composition as claimed in claim 1, wherein an insecticide from phenylpyrazole is selected from ethiprole, fipronil, flufiprole, nicofluprole, pyrafluprole, pyriprole

[CLAIM 4]. The synergistic granular agrochemical composition as claimed in claim 1, wherein an insecticide from pyrethroid is selected from bifenthrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin, deltamethrin, fenpropathrin, fenvalerate, tau-fluvalinate, permethrin, phenothrin, prallethrin, profluthrin, pyrethrin.

[CLAIM 5]. The synergistic granular agrochemical composition as claimed in claim 1, wherein nicotinic insecticides from class of neonicotinoids is selected from acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, thiamethoxam, flupyrimin, cycloxaprid, paichongding, guadipyr, cycloxylidin; from class of sulfoximines is sulfoxaflor; from class of butenolides is flupyradifurone from class of mesoionics is selected from triflumezopyrim, dichloromezotiaz, fenmezoditiaz.

[CLAIM 6]. The synergistic granular agrochemical composition as claimed in claim 1, wherein an insecticides from spinosyns is selected from spinosad, spinetoram.

[CLAIM 7]. The synergistic granular agrochemical composition as claimed in claim 1, wherein an insecticides from nereis toxin is selected from bensultap, monosultap, cartap hydrochloride, thiocyclam, thiocyclam hydrogen oxalate, thiocyclam hydrochloride, thiosultap sodium.

[CLAIM 8]. The synergistic granular agrochemical composition as claimed in claim 1, wherein formulation for the said agrochemical composition is selected from Granule (GR), Soil Applied Granules (SAG), Controlled release granules (CR) either slow release granule or fast release granules, micro-granules.

[CLAIM 9]. The synergistic granular agrochemical composition as claimed in claim 1, wherein the preferred combinations of active ingredients for granule formulation in said composition comprises:
a. Emamectin benzoate 0.12%w/w + Chlorantraniliprole 0.24% w/w + Cartap hydrochloride 4% w/w;
b. Emamectin benzoate 0.24% w/w +Tetraniliprole 0.9% w/w +Fipronil 1% w/w;
c. Emamectin benzoate 0.16% w/w +Chlorantraniliprole 0.32% w/w +Clothianidin 0.8%w/w;
d. Emamectin benzoate 0.16% w/w +Chlorantraniliprole 0.32% w/w +Thiamethoxam 0.8% w/w;
e. Emamectin benzoate 0.16% w/w +Chlorantraniliprole 0.32% w/w +Imidacloprid 0.5% w/w;
f. Emamectin benzoate 0.16% w/w +Chlorantraniliprole 0.32% w/w +Triflumezopyrim 0.24% w/w;
g. Emamectin benzoate 0.16% w/w +Chlorantraniliprole 0.32% w/w +Flupyrimin 1% w/w;
h. Emamectin benzoate 0.15% w/w +Chlorantraniliprole 0.25% w/w +Dichloromezotiaz 0.5% w/w;
i. Emamectin benzoate 0.12% w/w +Chlorantraniliprole 0.2% w/w +Cartap hydrochloride 4% w/w;
j. Emamectin benzoate 0.12% w/w +Chlorantraniliprole 0.2% w/w +Thiocyclam hydrogen oxalate 4% w/w;
k. Emamectin benzoate 0.3% w/w +Chlorantraniliprole 0.5% w/w +Fipronil 1% w/w;
l. Emamectin benzoate 0.3% w/w +Chlorantraniliprole 0.5% w/w +Spinetoram 1% w/w;
m. Emamectin benzoate 0.3% w/w +Tetraniliprole 0.6% w/w +Clothianidin 1% w/w;
n. Emamectin benzoate 0.3% w/w +Tetraniliprole 0.6% w/w +Thiamethoxam 1% w/w;
o. Emamectin benzoate 0.3% w/w +Tetraniliprole 0.6% w/w +Triflumezopyrim 0.5% w/w;
p. Emamectin benzoate 0.3% w/w +Tetraniliprole 0.6% w/w +Flupyrimin 1.5% w/w;
q. Emamectin benzoate 0.3% w/w +Tetraniliprole 0.6% w/w +Fipronil 1% w/w;
r. Emamectin benzoate 0.15% w/w +Tetraniliprole 0.3% w/w +Cartap hydrochloride 4% w/w.

[CLAIM 10]. The synergistic granular agrochemical composition as claimed in claim 1, wherein the composition for granule formulation comprises:
a. emamectin benzoate in an amount of 0.01% to 5% w/w;
b. an insecticide selected from Chlorantraniliprole, Cyantraniliprole, Tetraniliprole present in an amount of 0.1 % - 20 % w/w;
c. an insecticide selected from Cartap hydrochloride, Fipronil, Clothianidin, Flupyrimin, Dichloromezotiaz, Thiamethoxam, Imidacloprid, Triflumezopyrim present in an amount of 1-20% w/w
d. emulsifier present in an amount of 0.1-4.0%w/w;
e. buffering agent present in an amount of 0.1-1.0%w/w;
f. solvent present in an amount of 0.1-4.0%w/w;
g. dispersing agent present in an amount of 0.5-4.0%w/w;
h. colorant present in an amount of 0.01-1.0%w/w;
i. inert agent present in an amount of 0.5-3.0%w/w;
j. carrier present in an amount of 80-90%w/w.

[CLAIM 11]. The synergistic granular agrochemical composition as claimed in claim 10, wherein emulsifier is selected from mono C2-6 alkyl ether of a poly C2-4alkylene oxide block copolymer, condensation product of castor oil and poly C2-4alkylene oxide, alkoxylated castor oil is available under the trade name Agnique CSO-36, a mono- or di-ester of a C12-24fatty acid and polyC2-4alkylene oxide, carboxylates, sulphates, sulphonates, alcohol ethoxylates, Dodecyl hydroxypoly (oxy-1,2 ethanediyl) phosphate, alkyl phenol ethoxylates, fatty acid ethoxylates, sorbitan esters, ethoxylated fats or oils, amine ethoxylates, phosphate esters, ethylene oxide - propylene oxide copolymers, fluorocarbons,alkyd-polyethylene glycol resin, polyalkylene glycol ether, apolyalkoxylated nonyl phenyl, alkoxylated primary alcohol, ethoxylated distyrylphenol, ethoxylated distyrylphenol sulphate, ethoxylated tristyrylphenol phosphate, tristyrylphenol phosphate ester, hydroxylated stearic acid polyalkylene glycol polymer, and their corresponding salts,alkyd-polyethylene glycol resin, polyalkylene glycol ether, ethoxylated distyrylphenol, ethoxylated distyrylphenol sulphate, ethoxylated tristyrylphenol phosphate, tristyrylphenol phosphate ester, tristyrylphenol phosphate potassium salt, dodecysulfate sodium salt.

[CLAIM 12]. The synergistic granular agrochemical composition as claimed in claim 10, wherein dispersing agent is selected from copolymer of propylene oxide (PO) and ethylene oxide (EO) and/or an ethoxylated tristyrene phenol, copolymer of PO and EO is alpha-butyl-omega-hydroxypoly(oxypropylene) block polymer with poly(oxyethylene), ethoxylated tristyrene phenol is alpha-[2,4,6-tris[1-(phenyl)ethyl] phenyl]-omega-hydroxy poly(oxyethylene, poly(oxy-1,2-ethanediyl)-alpha-C10-15alkyl-omega-hydroxy phosphate or sulphate and/or a C10-13alkylbenzenesulfonic acid, tristyrylphenols, nonylphenols, dinonylphenol and octylphenols, styrylphenol polyethoxyester phosphate, alkoxylated C14-20 fatty amines, alkylnaphthalene sulfonate sodium salt, sodium polycarboxylate, naphthalene sulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalene sulfonic acid formaldehyde condensate, phenol sulfonic acid urea formaldehyde condensate, methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, polyacrylates and phosphate esters, calcium lignosulfonate, sodium lignosulfonate, sodium lignosulfonate-sulfomethylated.

[CLAIM 13]. The synergistic granular agrochemical composition as claimed in claim 10, wherein solvent is selected from fatty acid methyl ester, cyclohexane, xylene, mineral oil or kerosene, mixtures or substituted naphthalene, mixtures of mono- and poly alkylated aromatics, dibutyl phthalate or dioctyl phthalate, ethylene glycol monomethyl or mono ethyl ether, butyrolactone, octanol, castor oil, soybean oil, cottonseed oil, epoxidised coconut oil or soybean oil, aromatic hydrocarbons, dipropylene glycol mono methylether, polypropylene glycol [M.W. 2000-4000], polyoxyethylene polyoxypropylene glycols, polyoxypropylene polyoxyethylene glycols, diethyleneglycol, polyethylene glycol [M.W. 200-4000 amu], methoxy polyethylene glycols 350, 550, 750, 2000, 5000; glycerol, methyl oleate, n-octanol, alkyl phosphates such as tri-n-butyl phosphate, propylene carbonate and isoparaffinic, tetrahydrofurfuryl alcohol, gamma-butyrolactone, N-methyl-2-pyrrolidone, tetramethylurea, dimethylsulfoxide, N,N-dimethylacetamide, diacetone alcohol, polybutene, propylene carbonate, dipropylene glycol isomer mixture, water.

[CLAIM 14]. The synergistic granular agrochemical composition as claimed in claim 10, wherein colourant is selected from crystal violet, thalocyano dye chlorinated, aerosol green FFB dye, rodamine, azo compound.

[CLAIM 15]. The synergistic granular agrochemical composition as claimed in claim 10, wherein carrier is selected from diatomaceous earth, attapulgite or zeolites, dolomite, limestone, silica, river sand (Silica), sand, fly ash, hydrated lime, wheat flour, wood flour, ground wheat straw, cellulose and soy flour, bentonite, kaolin, attapulgite, diatomaceous earth, calcium carbonate, calcium silicate, magnesium stearate, talc, muscovite mica, fused sodium potassium, aluminum silicate, perlite, talc, muscovite mica, urea, sulfur-coated urea, isobutylidene diurea, ammonium nitrate, ammonium sulfate, ammonium phosphate, triple super phosphate, phosphoric acid, potassium sulfate, potassium nitrate, potassium metaphosphate, potassium chloride, dipotassium carbonate, potassium oxide.

[CLAIM 16]. The synergistic granular agrochemical composition as claimed in claim 10, wherein buffering agent is selected from calcium hydroxyapatite, phosphoric acid, sodium citrate, Potassium Dihydrogen Phosphate, Sodium Hydroxide, carbonated apatite, calcium carbonate, sodium bicarbonate, tricalcium phosphate, calcium phosphates, carbonated calcium phosphates, amine monomers, lactate dehydrogenase and magnesium hydroxide.

[CLAIM 17]. The synergistic granular agrochemical composition as claimed in claim 1, wherein the preferred combinations of active ingredients for Controlled Release Granule (CR-GR) formulation comprises in said composition comprises:
a. Emamectin benzoate 0.12%w/w+ Chlorantraniliprole 0.24% w/w +Cartap hydrochloride 4% w/w;
b. Emamectin benzoate 0.24% w/w +Tetraniliprole 0.9% w/w +Fipronil 1% w/w;
c. Emamectin benzoate 0.16% w/w +Chlorantraniliprole 0.4% w/w +Clothianidin 0.8% w/w;
d. Emamectin benzoate 0.15% w/w +Cyantraniliprole 0.5% w/w +Clothianidin 0.5% w/w;
e. Emamectin benzoate 0.15% w/w +Cyantraniliprole 0.5% w/w +Flupyrimin 0.75% w/w
f. Emamectin benzoate 2% w/w +Cyantraniliprole 10% w/w +Flupyrimin 16% w/w;
g. Emamectin benzoate 0.16% w/w +Chlorantraniliprole 0.32% w/w +Clothianidin 0.8%w/w;
h. Emamectin benzoate 0.16% w/w +Chlorantraniliprole 0.32% w/w +Thiamethoxam 0.8% w/w
i. Emamectin benzoate 0.16% w/w +Chlorantraniliprole 0.32% w/w +Imidacloprid 0.5% w/w;
j. Emamectin benzoate 0.16% w/w +Chlorantraniliprole 0.32% w/w +Triflumezopyrim 0.24% w/w;
k. Emamectin benzoate 0.16% w/w +Chlorantraniliprole 0.32% w/w +Flupyrimin 1% w/w;
l. Emamectin benzoate 0.15% w/w +Chlorantraniliprole 0.25% w/w +Dichloromezotiaz 0.5% w/w;
m. Emamectin benzoate 0.12% w/w +Chlorantraniliprole 0.2% w/w +Cartap hydrochloride 4% w/w;
n. Emamectin benzoate 0.12% w/w +Chlorantraniliprole 0.2% w/w +Thiocyclam hydrogen oxalate 4% w/w;
o. Emamectin benzoate 0.3% w/w +Chlorantraniliprole 0.5% w/w +Fipronil 1% w/w;
p. Emamectin benzoate 0.3% w/w +Chlorantraniliprole 0.5% w/w +Spinetoram 1% w/w;
q. Emamectin benzoate 0.15% w/w +Cyantraniliprole 0.5% w/w +Fipronil 0.5% w/w;
r. Emamectin benzoate 0.15% w/w +Cyantraniliprole 0.5% w/w +Clothianidin 0.5% w/w;
s. Emamectin benzoate 0.15% w/w +Cyantraniliprole 0.5% w/w +Triflumezopyrim 0.2% w/w;
t. Emamectin benzoate 0.15% w/w +Cyantraniliprole 0.5% w/w +Flupyrimin 0.75% w/w;
u. Emamectin benzoate 0.15% w/w +Cyantraniliprole 0.5% w/w +Cartap hydrochloride 4% w/w;
v. Emamectin benzoate 0.15% w/w +Cyantraniliprole 0.5% w/w +Thiocyclam hydrogen oxalate 4% w/w;
w. Emamectin benzoate 0.3% w/w +Tetraniliprole 0.6% w/w +Clothianidin 1% w/w;
x. Emamectin benzoate 0.3% w/w +Tetraniliprole 0.6% w/w +Thiamethoxam 1% w/w;
y. Emamectin benzoate 0.3% w/w +Tetraniliprole 0.6% w/w +Triflumezopyrim 0.5% w/w;
z. Emamectin benzoate 0.3% w/w +Tetraniliprole 0.6% w/w +Flupyrimin 1.5% w/w;
aa. Emamectin benzoate 0.3% w/w +Tetraniliprole 0.6% w/w +Fipronil 1% w/w;
bb. Emamectin benzoate 0.15% w/w +Tetraniliprole 0.3% w/w +Cartap hydrochloride 4% w/w;
cc. Emamectin benzoate 2% w/w +Chlorantraniliprole 5% w/w +Flupyrimin 16% w/w;
dd. Emamectin benzoate 2% w/w +Cyantraniliprole 10% w/w +Flupyrimin 16% w/w;
ee. Emamectin benzoate 2% w/w +Tetraniliprole 6% w/w +Flupyrimin 16% w/w;
ff. Emamectin benzoate 10% w/w +Chlorantraniliprole 25% w/w +Triflumezopyrim 20% w/w;
gg. Emamectin benzoate 5% w/w +Cyantraniliprole 25% w/w +Triflumezopyrim 10% w/w;
hh. Emamectin benzoate 5% w/w +Tetraniliprole 18% w/w +Triflumezopyrim 10% w/w.

[CLAIM 18]. The synergistic granular agrochemical composition as claimed in claim 1, wherein composition for Controlled Release Granule (CR-GR) formulation comprises in said composition comprises:
a. emamectin benzoate in an amount of 0.01% to 5% w/w;
b. an insecticide selected from Chlorantraniliprole, Cyantraniliprole, Tetraniliprole present in an amount of 0.1 % - 20 % w/w;
c. an insecticide selected from Cartap hydrochloride, Fipronil, Clothianidin, Flupyrimin, Dichloromezotiaz, Thiamethoxam, Imidacloprid, Triflumezopyrim present in an amount of 1-20% w/w;
d. controlled release agent present in an amount of 0.1-6.0%w/w;
e. emulsifier present in an amount of 0.1-4.0%w/w;
f. solvent present in an amount of 0.1-4.0%w/w;
g. dispersing agent present in an amount of 0.5-4.0%w/w;
h. colorant present in an amount of 0.01-1.0%w/w;
i. inert agent present in an amount of 0.5-3.0%w/w;
j. carrier present in an amount of 80-90%w/w.

[CLAIM 19]. The synergistic granular agrochemical composition as claimed in claim 18, wherein controlled release agent is selected from xanthan gum, PVK, carboxymethyl celluloses, polyvinyl alcohols, gelatin, sodium carboxymethyl cellulose, hydroxyethyl cellulose, Polyacrylic acid, sodium polyacrylate, modified starch, paraffin wax, polyvinyl acetate, montan wax and vinyl acetate, polyethylene glycol 6000, cationic hydrosoluble polymer, C4 alkylated polyvinyl pyrrolidone.

[CLAIM 20]. The synergistic granular agrochemical composition as claimed in claim 18, wherein emulsifier is selected from mono C2-6 alkyl ether of a poly C2-4alkylene oxide block copolymer, condensation product of castor oil and poly C2-4alkylene oxide, alkoxylated castor oil is available under the trade name Agnique CSO-36, a mono- or di-ester of a C12-24fatty acid and polyC2-4alkylene oxide, carboxylates, sulphates, sulphonates, alcohol ethoxylates, Dodecyl hydroxypoly (oxy-1,2 ethanediyl) phosphate, alkyl phenol ethoxylates, fatty acid ethoxylates, sorbitan esters, ethoxylated fats or oils, amine ethoxylates, phosphate esters, ethylene oxide - propylene oxide copolymers, fluorocarbons,alkyd-polyethylene glycol resin, polyalkylene glycol ether, apolyalkoxylated nonyl phenyl, alkoxylated primary alcohol, ethoxylated distyrylphenol, ethoxylated distyrylphenol sulphate, ethoxylated tristyrylphenol phosphate, tristyrylphenol phosphate ester, hydroxylated stearic acid polyalkylene glycol polymer, and their corresponding salts,alkyd-polyethylene glycol resin, polyalkylene glycol ether, ethoxylated distyrylphenol, ethoxylated distyrylphenol sulphate, ethoxylated tristyrylphenol phosphate, tristyrylphenol phosphate ester, tristyrylphenol phosphate potassium salt, dodecysulfate sodium salt.

[CLAIM 21]. The synergistic granular agrochemical composition as claimed in claim 18, wherein dispersing agent is selected from copolymer of propylene oxide (PO) and ethylene oxide (EO) and/or an ethoxylated tristyrene phenol, copolymer of PO and EO is alpha-butyl-omega-hydroxypoly(oxypropylene) block polymer with poly(oxyethylene), ethoxylated tristyrene phenol is alpha-[2,4,6-tris[1-(phenyl)ethyl] phenyl]-omega-hydroxy poly(oxyethylene, poly(oxy-1,2-ethanediyl)-alpha-C10-15alkyl-omega-hydroxy phosphate or sulphate and/or a C10-13alkylbenzenesulfonic acid, tristyrylphenols, nonylphenols, dinonylphenol and octylphenols, styrylphenol polyethoxyester phosphate, alkoxylated C14-20 fatty amines, alkylnaphthalene sulfonate sodium salt, sodium polycarboxylate, naphthalene sulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalene sulfonic acid formaldehyde condensate, phenol sulfonic acid urea formaldehyde condensate, methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, polyacrylates and phosphate esters, calcium lignosulfonate, sodium lignosulfonate, sodium lignosulfonate-sulfomethylated.

[CLAIM 22]. The synergistic granular agrochemical composition as claimed in claim 18, wherein solvent is selected from fatty acid methyl ester, cyclohexane, xylene, mineral oil or kerosene, mixtures or substituted naphthalene, mixtures of mono- and poly alkylated aromatics, dibutyl phthalate or dioctyl phthalate, ethylene glycol monomethyl or mono ethyl ether, butyrolactone, octanol, castor oil, soybean oil, cottonseed oil, epoxidised coconut oil or soybean oil, aromatic hydrocarbons, dipropylene glycol mono methylether, polypropylene glycol [M.W. 2000-4000], polyoxyethylene polyoxypropylene glycols, polyoxypropylene polyoxyethylene glycols, diethyleneglycol, polyethylene glycol [M.W. 200-4000 amu], methoxy polyethylene glycols 350, 550, 750, 2000, 5000; glycerol, methyl oleate, n-octanol, alkyl phosphates such as tri-n-butyl phosphate, propylene carbonate and isoparaffinic, tetrahydrofurfuryl alcohol, gamma-butyrolactone, N-methyl-2-pyrrolidone, tetramethylurea, dimethylsulfoxide, N,N-dimethylacetamide, diacetone alcohol, polybutene, propylene carbonate, dipropylene glycol isomer mixture, water.

[CLAIM 23]. The synergistic granular agrochemical composition as claimed in claim 18, wherein carrier is selected from diatomaceous earth, attapulgite or zeolites, dolomite, limestone, silica, river sand (Silica), sand, fly ash, hydrated lime, wheat flour, wood flour, ground wheat straw, cellulose and soy flour, bentonite, kaolin, attapulgite, diatomaceous earth, calcium carbonate, calcium silicate, magnesium stearate, talc, muscovite mica, fused sodium potassium, aluminum silicate, perlite, talc, muscovite mica, urea, sulfur-coated urea, isobutylidene diurea, ammonium nitrate, ammonium sulfate, ammonium phosphate, triple super phosphate, phosphoric acid, potassium sulfate, potassium nitrate, potassium metaphosphate, potassium chloride, dipotassium carbonate, potassium oxide.

[CLAIM 24]. The synergistic granular agrochemical composition as claimed in claim 1, wherein composition for micro-granule formulation in said composition comprises:
a. emamectin benzoate in an amount of 0.01% to 5% w/w;
b. an insecticide selected from Chlorantraniliprole, Cyantraniliprole, Tetraniliprole present in an amount of 0.1 % - 20 % w/w;
c. an insecticide selected from Cartap hydrochloride, Fipronil, Clothianidin, Flupyrimin, Dichloromezotiaz, Thiamethoxam, Imidacloprid, Triflumezopyrim present in an amount of 1-20% w/w;
d. wetting agent present in an amount of 0.1-6.0%w/w;
e. dispersing agent present in an amount of 0.1-4.0%w/w;
f. antifoaming agent present in an amount of 0.01-2.0%w/w;
g. humectant present in an amount of 2.0-8.0%w/w;
h. carrier present in an amount of 20.0-30.0%w/w.

[CLAIM 25]. The synergistic granular agrochemical composition as claimed in claim 24, wherein dispersing agent is selected from sodium polycarboxylate (sodium polyacrylate), naphthalene sulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalene sulfonic acid formaldehyde condensate, methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, lignosulfonates, calcium lignosulfonate, lignin sulfonate sodium salt, alkyl naphthalene sulfonate sodium salt.

[CLAIM 26]. The synergistic granular agrochemical composition as claimed in claim 24, wherein wetting agent is selected from sodium N-methyl-N-oleoyl taurate, alkylated naphthalene sulfonate, sodium salt, mixture of isomers of dibutyl naphthalene sulphonic acid sodium salt, sodium di-isopropyl naphthalene sulphonate, sodium Lauryl sulfate, dioctyl sulfate, alkyl naphthalene sulfonates, phosphate esters, sulphosuccinates and non-ionic such as tridecyl alcohol ethoxylate, alkyl or alkaryl sulfonates such as alkylbenzene sulfonates, alpha olefin sulfonate and alkyl naphthalene sulfonates, ethoxylated or non-ethoxylated alkyl or alkaryl carboxylates, alkyl or alkaryl phosphate esters, alkyl polysaccharide, di or mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, alkyl naphthalene sulfonates, dialkyl sulphosuccinates, butyl, dibutyl, isopropyl and di-isopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate or C10-C16 alkyl benzene sulfonate, organosilicons surfactants includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, trisiloxane heptamethyl, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, may or may not be in modified form, may be liquid or powder form or mixture thereof.

[CLAIM 27]. The synergistic granular agrochemical composition as claimed in claim 24, wherein anti-foaming agent is polydimethylsiloxane.

[CLAIM 28]. The synergistic granular agrochemical composition as claimed in claim 24, wherein humectant is selected from humic acid, glycerol, lactose, Sodium sulphate anhydrous.

Dated this 30th day of August 2022.