Anthranilamides, their use as insecticide and processes for preparing the same.

FIELD OF THE INVENTION:

The present invention relates to novel anthranilamides, to their use as insecticides and acaricides, to their combination with other active compounds, and to processes for their preparation.

BACKGROUND:

Anthranilic acid derivatives having insecticidal properties have already been described in the literature. For example in W02001070671, W02003015518, W02003015519, W02003016284, W02003024222,

W02003016282, W02003016283, W02003062226, W02003027099, W02004027042, W02004033468, W02004046129, W02004067528, WO2005118552, W02005077934, W02005085234, W02006023783, W02006000336, W02006040113, W02006062978,

W02006111341, W02007009661, W02007006670, W 02007020050, W02007024833, W02007020877, W02007144100, W02007043677, W02007093402, W02008010897, W02008070158, W02008072743, W02008072745, W02008082502, WO2008126889, W02008126890, WO2008126933, WO2010069502, WO2011157778, WO2011157654, WO2011157651, WO2011157663, WO2011157664, W02012010525, WO2012004221,

W02013007604, W02013030100, W02014079820, WO2014135588, CN103450154, CN106588870 and CN106810535.

The active compounds reported in the above literature have disadvantages in certain aspects, such as that they exhibit a narrow spectrum of application or they do not have satisfactory insecticidal or acaricidal activity.

SUMMARY:

The present invention relates to anthranilamides which have now been found to be advantages over the compounds reported in the literature in either of improved insecticidal or acaricidal activity, biological or environmental properties, broader spectrum of application or enhanced plant compatibility.

The anthranilamides of the present invention can be used in combination with other biologically active compounds for improving the efficacy particularly against insects which are difficult to control.

The present invention also relates to a plurality of processes for the preparation of anthranilamides.

Accordingly, the present invention provides novel anthranilamides of Formula I,

wherein,

the definition of W1, W2, D, Z1, E, R1, R2, R3, R4, m is as described in the following description.

DETAILED DESCRIPTION OF THE INVENTION:

DEFINITIONS:

The definitions provided herein for the terminologies used in the present disclosure are for illustrative purpose only and in no manner limit the scope of the present invention disclosed in the present disclosure.

As used herein, the terms “comprises”, “comprising”, “includes”, “including”, “has”, “having”, “contains”,“containing”,“characterized by” or any other variation thereof, are intended to cover a non-exclusive inclusion, subject to any limitation explicitly indicated. For example, a composition, mixture, process or method that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, mixture, process or method.

The transitional phrase“consisting of’ excludes any element, step or ingredient not specified. If in the claim, such would close the claim to the inclusion of materials other than those recited except for impurities ordinarily associated therewith. When the phrase“consisting of’ appears in a clause of the body of a claim, rather than immediately following the preamble, it limits only the element set forth in that clause; other elements are not excluded from the claim as a whole.

The transitional phrase“consisting essentially of’ is used to define a composition or method that includes materials, steps, features, components or elements, in addition to those literally disclosed, provided that these additional materials, steps, features, components or elements do not materially affect the basic and novel characteristic(s) of the claimed invention. The term“consisting essentially of’ occupies a middle ground between“comprising” and“consisting of’.

Further, unless expressly stated to the contrary,“or” refers to an inclusive“or” and not to an exclusive “or”. For example, a condition A“or” B is satisfied by any one of the following: A is true (or present) and B is false (or not present), A is false (or not present) and B is true (or present), and both A and B are true (or present).

Also, the indefinite articles“a” and“an” preceding an element or component of the present invention are intended to be nonrestrictive regarding the number of instances (i.e. occurrences) of the element or component. Therefore“a” or“an” should be read to include one or at least one, and the singular word form of the element or component also includes the plural unless the number is obviously meant to be singular.

As referred to in this disclosure, the term“invertebrate pest” includes arthropods, gastropods and nematodes of economic importance as pests. The term“arthropod” includes insects, mites, spiders, scorpions, centipedes, millipedes, pill bugs and symphylans. The term“gastropod” includes snails, slugs and other Stylommatophora. The term“nematode” refers to a living organism of the Phylum Nematoda. The term“helminths” includes roundworms, heartworms, phytophagous nematodes (Nematoda), flukes (Tematoda), acanthocephala and tapeworms (Cestoda).

In the context of this disclosure “invertebrate pest control” means inhibition of invertebrate pest development (including mortality, feeding reduction, and/or mating disruption), and related expressions are defined analogously.

The term“agronomic” refers to the production of field crops such as for food and fiber and includes the growth of corn, soybeans and other legumes, rice, cereal (e.g., wheat, oats, barley, rye, rice, maize), leafy vegetables (e.g., lettuce, cabbage, and other cole crops), fruiting vegetables (e.g., tomatoes, pepper, eggplant, crucifers and cucurbits), potatoes, sweet potatoes, grapes, cotton, tree fruits (e.g., pome, stone and citrus), small fruit (berries, cherries) and other specialty crops (e.g., canola, sunflower, olives).

The term“nonagronomic” refers to other than field crops, such as horticultural crops (e.g., greenhouse, nursery or ornamental plants not grown in a field), residential, agricultural, commercial and industrial structures, turf (e.g., sod farm, pasture, golf course, lawn, sports field, etc.), wood products, stored product, agro-forestry and vegetation management, public health (i.e. human) and animal health (e.g.,

domesticated animals such as pets, livestock and poultry, undomesticated animals such as wildlife) applications.

Nonagronomic applications include protecting an animal from an invertebrate parasitic pest by administering a parasiticidally effective (i.e. biologically effective) amount of a compound of the present invention, typically in the form of a composition formulated for veterinary use, to the animal to be protected. As referred to in the present disclosure and claims, the terms “parasiticidal” and “parasiticidally” refers to observable effects on an invertebrate parasite pest to provide protection of an animal from the pest. Parasiticidal effects typically relate to diminishing the occurrence or activity of the target invertebrate parasitic pest. Such effects on the pest include necrosis, death, retarded growth, diminished mobility or lessened ability to remain on or in the host animal, reduced feeding and inhibition of reproduction. These effects on invertebrate parasite pests provide control (including prevention, reduction or elimination) of parasitic infestation or infection of the animal.

The compounds of the present disclosure may be present either in pure form or as mixtures of different possible isomeric forms such as stereoisomers or constitutional isomers. The various stereoisomers include enantiomers, diastereomers, chiral isomers, atropisomers, conformers, rotamers, tautomers, optical isomers, polymorphs, and geometric isomers. Any desired mixtures of these isomers fall within the scope of the claims of the present disclosure. One skilled in the art will appreciate that one stereoisomer may be more active and/or may exhibit beneficial effects when enriched relative to the other isomer(s) or when separated from the other isomer(s). Additionally, the person skilled in the art knows processes or methods or technology to separate, enrich, and/or to selectively prepare said isomers.

The meaning of various terms used in the description shall now be illustrated.

The term“alkyl”, used either alone or in compound words such as“alkylthio” or“haloalkyl” or -N(alkyl) or alkylcarbonylalkyl or alkylsuphonylamino includes straight-chain or branched Ci to C24 alkyl, preferably Ci to C15 alkyl, more preferably Ci to C10 alkyl, most preferably Ci to Cr, alkyl. Non limiting examples of alkyl include methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1,1-dimethylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, 1,1-dimethylpropyl, 1 ,2-dimethylpropyl, 1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4-methylpentyl, 1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl, 2-ethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl, 1 -ethyl- 1-methylpropyl and l-ethyl-2-methylpropyl or the different isomers. If the alkyl is at the end of a composite substituent, as, for example, in alkylcycloalkyl, the part of the composite substituent at the start, for example the cycloalkyl, may be mono- or polysubstituted identically or differently and independently by alkyl. The same also applies to composite substituents in which other radicals, for example alkenyl, alkynyl, hydroxyl, halogen, carbonyl, carbonyloxy and the like, are at the end.

The term“alkenyl”, used either alone or in compound words includes straight-chain or branched C2 to C24 alkenes, preferably C2 to C15 alkenes, more preferably C2 to C10 alkenes, most preferably C2 to Cr, alkenes. Non limiting examples of alkenes include ethenyl, 1-propenyl, 2-propenyl, 1-methylethenyl, 1-butenyl, 2-butenyl, 3-butenyl, 1 -methyl- 1-propenyl, 2-methyl -1-propenyl, l-methyl-2 -propenyl, 2-methyl-2-propenyl, 1-pentenyl, 2-pentenyl, 3-pentenyl, 4-pentenyl, 1 -methyl- 1-butenyl, 2-methyl- 1-butenyl, 3-methyl- 1-butenyl, l-methyl-2 -butenyl, 2-methyl-2-butenyl, 3 -methyl-2 -butenyl, l-methyl-3-butenyl, 2-methyl-3-butenyl, 3 -methyl-3 -butenyl, l,l-dimethyl-2-propenyl, 1,2-dimethyl- 1-propenyl, l,2-dimethyl-2 -propenyl, 1 -ethyl- 1-propenyl, l-ethyl-2 -propenyl, 1-hexenyl, 2-hexenyl, 3-hexenyl, 4-hexenyl, 5-hexenyl, 1 -methyl- 1-pentenyl, 2-methyl- 1-pentenyl, 3-methyl-l-pentenyl, 4-methyl- 1-pentenyl, l-methyl-2-pentenyl, 2-methyl-2-pentenyl, 3-methyl-2-pentenyl, 4 -methyl -2-pentenyl, l-methyl-3-pentenyl, 2-methyl-3-pentenyl, 3-methyl-3-pentenyl, 4-methyl-3-pentenyl, l-methyl-4-pentenyl, 2-methyl-4-pentenyl, 3-methyl-4-pentenyl, 4-methyl-4-pentenyl, 1,1 -dimethyl -2 -butenyl, l,l-dimethyl-3-butenyl, 1,2-dimethyl-l-butenyl, 1,2-dimethyl -2 -butenyl, l,2-dimethyl-3-butenyl, 1,3 -dimethyl- 1-butenyl, l,3-dimethyl-2-butenyl, l,3-dimethyl-3-butenyl, 2, 2-dimethy 1-3 -butenyl, 2,3-dimethyl-l-butenyl, 2,3-dimethyl-2-butenyl, 2,3-dimethyl-3-butenyl, 3,3-dimethyl-l-butenyl, 3,3-dimethyl-2-butenyl, 1 -ethyl- 1-butenyl, l-ethyl-2-butenyl, l-ethyl-3-butenyl, 2-ethyl- 1-butenyl, 2-ethyl-2-butenyl, 2 -ethyl-3 -butenyl, l,l,2-trimethyl-2-propenyl, 1-ethyl-l-methyl-2-propenyl, l-ethyl-2-methyl-l-propenyl and l-ethyl-2-methyl-2 -propenyl and the different isomers.“Alkenyl” also includes polyenes such as 1,2-propadienyl and 2,4-hexadienyl. This definition also applies to alkenyl as a part of a composite substituent, for example haloalkenyl and the like, unless defined specifically elsewhere.

Non limiting examples of alkynes include ethynyl, 1-propynyl, 2-propynyl, 1-butynyl, 2-butynyl, 3-butynyl, l-methyl-2-propynyl, 1-pentynyl, 2-pentynyl, 3-pentynyl, 4-pentynyl, l-methyl-2 -butynyl, 1-methyl-3-butynyl, 2-methyl-3-butynyl, 3 -methyl -1-butynyl, 1,1 -dimethyl-2 -prop ynyl, 1-ethyl -2-propynyl,

1-hexynyl, 2-hexynyl, 3-hexynyl, 4-hexynyl, 5-hexynyl, 1 -methyl -2-pentynyl, l-methyl-3-pentynyl, 1-methyl-4-pentynyl, 2-methyl-3-pentynyl, 2-methyl-4-pentynyl, 3-methyl-l-pentynyl, 3-methyl-4-pentynyl, 4-methyl-l-pentynyl, 4-methyl-2-pentynyl, 1,1 -dimethyl-2 -butynyl, l,l-dimethyl-3-butynyl, 1,2-dimethyl-3-butynyl, 2,2-dimethyl-3-butynyl, 3,3-dimethyl-l-butynyl, l-ethyl-2 -butynyl, l-ethyl-3-butynyl,

2-ethyl-3-butynyl and l-ethyl-l-methyl-2-propynyl and the different isomers. This definition also applies to alkynyl as a part of a composite substituent, for example haloalkynyl etc., unless specifically defined elsewhere. The term“ Alkynyl” can also include moieties comprised of multiple triple bonds such as 2,5-hexadiynyl.

The term“cycloalkyl” means alkyl closed to form a ring. Non limiting examples include cyclopropyl, cyclopentyl and cyclohexyl. This definition also applies to cycloalkyl as a part of a composite substituent, for example cycloalkylalkyl etc., unless specifically defined elsewhere.

The term“cycloalkenyl” means alkenyl closed to form a ring including monocyclic, partially unsaturated hydrocarbyl groups. Non limiting examples include cyclopropenyl, cyclopentenyl and cyclohexenyl. This definition also applies to cycloalkenyl as a part of a composite substituent, for example cycloalkenylalkyl etc., unless specifically defined elsewhere.

The term“cycloalkynyl” means alkynyl closed to form a ring including monocyclic, partially unsaturated groups. Non limiting examples include cyclopropynyl, cyclopentynyl and cyclohexynyl. This definition also applies to cycloalkynyl as a part of a composite substituent, for example cycloalkynylalkyl etc., unless specifically defined elsewhere.

The terms“cycloalkoxy”,“cycloalkenyloxy” and the like are defined analogously. Non limiting examples of cycloalkoxy include cyclopropyloxy, cyclopentyloxy and cyclohexyloxy. This definition also applies to cycloalkoxy as a part of a composite substituent, for example cycloalkoxy alkyl etc., unless specifically defined elsewhere.

The term“halogen”, either alone or in compound words such as“haloalkyl”, includes fluorine, chlorine, bromine or iodine. Further, when used in compound words such as“haloalkyl”, said alkyl may be partially or fully substituted with halogen atoms which may be the same or different. Non-limiting Examples of “haloalkyl” include chloromethyl, bromomethyl, dichloromethyl, trichloromethyl, fluoromethyl, difluoromethyl, trifluoromethyl, chlorofluoromethyl, dichlorofluoromethyl, chlorodifluoromethyl, 1-chloroethyl, 1-bromoethyl, 1-fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, 2-chloro-2-fluoroethyl, 2-chloro-2,2-difluoroethyl, 2,2-dichloro-2-fluoroethyl, 2,2,2-trichloroethyl, pentafluoroethyl, 1,1-di chi oro-2, 2, 2-triflu oroethyl, and l,l,l-trifluoroprop-2-yl. This definition also applies to haloalkyl as a part of a composite substituent, for example haloalkylaminoalkyl etc., unless specifically defined elsewhere.

The terms“haloalkenyl”,“haloalkynyl” are defined analogously except that, instead of alkyl groups, alkenyl and alkynyl groups are present as a part of the substituent.

The term“haloalkoxy” means straight-chain or branched alkoxy groups where some or all of the hydrogen atoms in these groups may be replaced by halogen atoms as specified above. Non-limiting examples of haloalkoxy include chloromethoxy, bromomethoxy, dichloromethoxy, trichloromethoxy, fluoromethoxy, difluoromethoxy, trifluoromethoxy, chlorofluoromethoxy, dichlorofluoromethoxy, chlorodifluoromethoxy, 1-chloroethoxy, 1-bromoethoxy, 1-fluoroethoxy, 2-fluoroethoxy, 2,2-difluoroethoxy, 2,2,2-trifluoroethoxy, 2-chloro-2-fluoroethoxy, 2-chloro-2,2-difluoroethoxy, 2,2-dichloro- 2-fluoroethoxy, 2,2,2-trichloroethoxy, pentafluoroethoxy and l,l,l-trifluoroprop-2-oxy. This definition also applies to haloalkoxy as a part of a composite substituent, for example haloalkoxyalkyl etc., unless specifically defined elsewhere.

The term“haloalkylthio” means straight-chain or branched alkylthio groups where some or all of the hydrogen atoms in these groups may be replaced by halogen atoms as specified above. Non-limiting examples of haloalkylthio include chloromethylthio, bromomethylthio, dichloromethylthio, trichloromethylthio, fluoromethylthio, difluoromethylthio, trifluoromethylthio, chlorofluoromethylthio, dichlorofluoromethylthio, chlorodifluoromethylthio, 1-chloroethylthio, 1-bromoethylthio, 1-fluoroethylthio, 2-fluoroethylthio, 2,2-difluoroethylthio, 2,2,2-trifluoroethylthio, 2-chloro-2-fluoroethylthio, 2-chloro-2,2-difluoroethylthio, 2,2-dichloro-2-fluoroethylthio, 2,2,2-trichloroethylthio, pentafluoroethylthio and l,l,l-trifluoroprop-2-ylthio. This definition also applies to haloalkylthio as a part of a composite substituent, for example haloalkylthioalkyl etc., unless specifically defined elsewhere.

Non limiting examples of“haloalkylsulfinyl” include CF3S(0), CCUStO), CF3CH2S(0) and CF3CF2S(0). Examples of“haloalkylsulfonyl” include CF3S(0)2, CC13S(0)2, CF3CH2S(0)2 and CF3CF2S(0)2.

The trerm“hydroxy” means -OH, Amino means -NRR, wherein R can be H or any possible substituent such as alkyl. Carbonyl means -C(O)- , carbonyloxy means -OC(O)-, sulfinyl means SO, sulfonyl means S(0)2.

The term“alkoxy” used either alone or in compound words included Ci to CM alkoxy, preferably Ci to Cis alkoxy, more preferably Ci to Cio alkoxy, most preferably Ci to Cr, alkoxy. Examples of alkoxy include methoxy, ethoxy, propoxy, 1-methylethoxy, butoxy, 1-methylpropoxy, 2-methylpropoxy, 1,1-dimethylethoxy, pentoxy, 1-methylbutoxy, 2-methylbutoxy, 3-methylbutoxy, 2,2-dimethylpropoxy, 1-ethylpropoxy, hexoxy, 1,1-dimethylpropoxy, 1,2-dimethylpropoxy, 1-methylpentoxy, 2-methylpentoxy,

3-methylpentoxy, 4-methylpentoxy, 1,1-dimethylbutoxy, 1 ,2-dimethylbutoxy, 1,3-dimethylbutoxy, 2,2-dimethylbutoxy, 2,3-dimethylbutoxy, 3,3-dimethylbutoxy, 1-ethylbutoxy, 2-ethylbutoxy, 1,1,2-trimethylpropoxy, 1,2,2-trimethylpropoxy, 1 -ethyl- 1-methylpropoxy and l-ethyl-2-methylpropoxy and the

different isomers. This definition also applies to alkoxy as a part of a composite substituent, for example haloalkoxy, alkynylalkoxy, etc., unless specifically defined elsewhere.

The term “alkoxyalkyl” denotes alkoxy substitution on alkyl. Examples of “alkoxyalkyl” include CH3OCH2, CH3OCH2CH2, CH3CH2OCH2, CH3CH2CH2CH2OCH2 and CH3CH2OCH2CH2.

The term“alkoxyalkoxy” denotes alkoxy substitution on alkoxy.

The term“alkylthio” includes branched or straight-chain alkylthio moieties such as methylthio, ethylthio, propylthio, 1-methylethylthio, butylthio, 1-methylpropylthio, 2-methylpropylthio, 1,1-dimethylethylthio, pentylthio, 1-methylbutylthio, 2-methylbutylthio, 3-methylbutylthio, 2,2-dimethylpropylthio, 1-ethylpropylthio, hexylthio, 1,1-dimethylpropylthio, 1,2-dimethylpropylthio, 1-methylpentylthio, 2-methylpentylthio, 3-methylpentylthio, 4-methylpentylthio, 1,1-dimethylbutylthio, 1,2-dimethylbutylthio, 1,3-dimethylbutylthio, 2,2-dimethylbutylthio, 2,3-dimethylbutylthio, 3,3-dimethylbutylthio, 1-ethylbutylthio, 2-ethylbutylthio, 1,1,2-trimethylpropylthio, 1 ,2,2-trimethylpropylthio, 1 -ethyl- 1-methylpropylthio and l-ethyl-2-methylpropylthio and the different isomers.

The terms Halocycloalkyl, halocycloalkenyl, alkylcycloalkyl, cycloalkylalkyl, cycloalkoxyalkyl, alkylsulfinylalkyl, alkylsulfonylalkyl, haloalkylcarbonyl, cycloalkylcarbonyl, haloalkoxylalkyl, and the like, are defined analogously to the above examples.

The term “alkylthioalkyl” denotes alkylthio substitution on alkyl. Non limiting examples of

“alkylthioalkyl” include -CH2SCH2, -CH2SCH2CH2, CH3CH2SCH2, CH3CH2CH2CH2SCH2 and CH3CH2SCH2CH2. “Alkylthioalkoxy” denotes alkylthio substitution on alkoxy. The term

“cycloalkylalkylamino” denotes cycloalkyl substitution on alkyl amino.

The terms alkoxyalkoxyalkyl, alkylaminoalkyl, dialkylaminoalkyl, cycloalkylaminoalkyl, cycloalkylaminocarbonyl and the like, are defined analogously to “alkylthioalkyl” or cycloalkylalkylamino.

The term“alkoxycarbonyl” is an alkoxy group bonded to a skeleton via a carbonyl group (-CO-). This definition also applies to alkoxycarbonyl as a part of a composite substituent, for example cycloalkylalkoxycarbonyl and the like, unless specifically defined elsewhere.

The term “alkoxycarbonylalkylamino” denotes alkoxy carbonyl substitution on alkyl amino. “Alkylcarbonylalkylamino” denotes alkyl carbonyl substitution on alkyl amino. The terms alkylthioalkoxycarbonyl, cycloalkylalkylaminoalkyl and the like are defined analogously.

Non limiting examples of “alkylsulfinyl” include methylsulphinyl, ethylsulphinyl, propylsulphinyl, 1-methylethylsulphinyl, butylsulphinyl, 1-methylpropylsulphinyl, 2-methylpropylsulphinyl, 1,1-dimethylethylsulphinyl, pentylsulphinyl, 1-methylbutylsulphinyl, 2-methylbutylsulphinyl, 3-methylbutylsulphinyl, 2,2-dimethylpropylsulphinyl, 1-ethylpropylsulphinyl, hexylsulphinyl, 1,1-dimethylpropylsulphinyl, 1 ,2-dimethylpropylsulphinyl, 1-methylpentylsulphinyl, 2-methylpentylsulphinyl, 3-methylpentylsulphinyl, 4-methylpentylsulphinyl, 1 , 1 -dimethylbutylsulphinyl,

1.2-dimethylbutylsulphinyl, 1,3 -dimethylbutylsulphinyl, 2,2-dimethylbutylsulphinyl, 2,3-dimethylbutylsulphinyl, 3, 3 -dimethylbutylsulphinyl, 1 -ethylbutylsulphinyl, 2-ethylbutylsulphinyl, 1,1,2-trimethylpropylsulphinyl, 1,2,2-trimethylpropylsulphinyl, 1 -ethyl- 1-methylpropylsulphinyl and l-ethyl-2-methylpropylsulphinyl and the different isomers. The term“arylsulfinyl” includes Ar-S(O), wherein Ar can be any carbocyle or heterocylcle. This definition also applies to alkylsulphinyl as a part of a composite substituent, for example haloalkylsulphinyl etc., unless specifically defined elsewhere.

Non limiting examples of“alkylsulfonyl” include methylsulphonyl, ethylsulphonyl, propylsulphonyl, 1-methylethylsulphonyl, butylsulphonyl, 1-methylpropylsulphonyl, 2-methylpropylsulphonyl, 1,1-dimethylethylsulphonyl, pentylsulphonyl, 1 -methylbutylsulphonyl, 2-methylbutylsulphonyl, 3-methylbutylsulphonyl, 2,2-dimethylpropylsulphonyl, 1-ethylpropylsulphonyl, hexylsulphonyl, 1,1-dimethylpropylsulphonyl, 1 ,2-dimethylpropylsulphonyl, 1-methylpentylsulphonyl, 2-methylpentylsulphonyl, 3 -methylpentylsulphonyl, 4-methylpentylsulphonyl, 1 , 1 -dimethylbutylsulphonyl,

1.2-dimethylbutylsulphonyl, 1,3-dimethylbutylsulphonyl, 2,2-dimethylbutylsulphonyl, 2,3-dimethylbutylsulphonyl, 3 ,3 -dimethylbutylsulphonyl, 1 -ethylbutylsulphonyl, 2-ethylbutylsulphonyl,

1.1.2-trimethylpropylsulphonyl, 1,2,2-trimethylpropylsulphonyl, 1 -ethyl- 1-methylpropylsulphonyl and 1-ethyl-2-methylpropylsulphonyl and the different isomers. The term“arylsulfonyl” includes Ar-S(0)2, wherein Ar can be any carbocyle or heterocylcle. This definition also applies to alkylsulphonyl as a part of a composite substituent, for example alkylsulphonylalkyl etc., unless defined elsewhere.

The term“alkylamino”,“dialkylamino”, and the like, are defined analogously to the above examples.

The term“carbocycle” includes“aromatic carbocyclic ring system” and“nonaromatic carbocylic ring system” or polycyclic or bicyclic (spiro, fused, bridged, nonfused) ring compounds in which ring may be aromatic or non-aromatic (where aromatic indicates that the Huckel rule is satisfied and non-aromatic indicates that the Huckel rule is not statisfied).

The term“hetero” in connection with rings refers to a ring in which at least one ring atom is not carbon and which can contain 1 to 4 heteroatoms independently selected from the group consisting of nitrogen, oxygen and sulfur, provided that each ring contains no more than 4 nitrogens, no more than 2 oxygens and no more than 2 sulfurs.

The term“heteroaryl” or“aromatic heterocyclic” means 5 or 6-membered, fully unsaturated monocyclic ring system containing one to four heteroatoms from the group of oxygen, nitrogen and sulphur; if the ring contains more than one oxygen atom, they are not directly adjacent; 5-membered heteroaryl containing one to four nitrogen atoms or one to three nitrogen atoms and one sulphur or oxygen atom: 5-membered heteroaryl groups which, in addition to carbon atoms, may contain one to four nitrogen atoms or one to three nitrogen atoms and one sulphur or oxygen atom as ring members, for example (but not limited thereto) furyl, thienyl, pyrrolyl, isoxazolyl, isothiazolyl, pyrazolyl, oxazolyl, thiazolyl, imidazolyl, 1,2,4-oxadiazolyl, 1,2,4-thiadiazolyl, 1,2,4-triazolyl, 1,3,4-oxadiazolyl, 1,3,4-thiadiazolyl, 1,3,4-triazolyl, tetrazolyl; nitrogen-bonded 5-membered heteroaryl containing one to four nitrogen atoms, or benzofused nitrogen-bonded 5-membered heteroaryl containing one to three nitrogen atoms: 5-membered heteroaryl groups which, in addition to carbon atoms, may contain one to four nitrogen atoms or one to three nitrogen atoms as ring members and in which two adjacent carbon ring members or one nitrogen and one adjacent carbon ring member may be bridged by a buta-l,3-diene-l,4-diyl group in which one or two carbon atoms may be replaced by nitrogen atoms, where these rings are attached to the skeleton via one of the nitrogen ring members, for example (but not limited to) 1-pyrrolyl, 1-pyrazolyl, 1,2,4-triazol-l- yl, 1-imidazolyl, 1,2,3-triazol-l-yl and 1,3,4-triazol-l-yl..

6-membered heteroaryl which contains one to four nitrogen atoms: 6-membered heteroaryl groups which, in addition to carbon atoms, may contain, respectively, one to three and one to four nitrogen atoms as ring members, for example (but not limited thereto) 2-pyridinyl, 3-pyridinyl, 4-pyridinyl, 3-pyridazinyl, 4-pyridazinyl, 2-pyrimidinyl, 4-pyrimidinyl, 5-pyrimidinyl, 2-pyrazinyl, l,3,5-triazin-2-yl, l,2,4-triazin-3-yl and l,2,4,5-tetrazin-3-yl; benzofused 5-membered heteroaryl containing one to three nitrogen atoms or one nitrogen atom and one oxygen or sulphur atom: for example (but not limited to) indol-l-yl, indol-2-yl, indol-3-yl, indol-4-yl, indol-5-yl, indol-6-yl, indol-7-yl, benzimidazol-l-yl, benzimidazol-2-yl, benzimidazol-4-yl, benzimidazol-5-yl, indazol-l-yl, indazol-3-yl, indazol-4-yl, indazol-5-yl, indazol-6-yl, indazol-7-yl, indazol-2-yl, l-benzofuran-2-yl, l-benzofuran-3-yl, l-benzofuran-4-yl, l-benzofuran-5-yl, 1-benzofuran- 6-yl, l-benzofuran-7-yl, l-benzothiophen-2-yl, l-benzothiophen-3-yl, l-benzothiophen-4-yl, 1-benzothiophen-5-yl, l-benzothiophen-6-yl, l-benzothiophen-7-yl, l,3-benzothiazol-2-yl, 1,3- benzothiazol-4-yl, l,3-benzothiazol-5-yl, l,3-benzothiazol-6-yl, l,3-benzothiazol-7-yl, l,3-benzoxazol-2-yl, 1,3-benzoxazol-4-yl, l,3-benzoxazol-5-yl, l,3-benzoxazol-6-yl and l,3-benzoxazol-7-yl; benzofused 6-membered heteroaryl which contains one to three nitrogen atoms: for example (but not limited to) quinolin-2-yl, quinolin-3-yl, quinolin-4-yl, quinolin-5-yl, quinolin-6-yl, quinolin-7-yl, quinolin-8-yl,

isoquinolin-l-yl, isoquinolin-3-yl, isoquinolin-4-yl, isoquinolin-5-yl, isoquinolin-6-yl, isoquinolin-7-yl and isoquinolin-8-yl.

This definition also applies to heteroaryl as a part of a composite substituent, for example heteroarylalkyl etc., unless specifically defined elsewhere.

The term“aromatic” indicates that the Huckel rule is satisfied and the term“non-aromatic” indicates that the Huckel rule is not satisfied.

The term“heterocycle” or“heterocyclic” includes“aromatic heterocycle” or“heteroaryl ring system” and “nonaromatic heterocycle ring system” or polycyclic or bicyclic (spiro, fused, bridged, non-fused) ring compounds in which ring may be aromatic or non-aromatic, wherein the heterocycle ring contains at least one heteroatom selected from N, O, S(0)o-2, and or C ring member of the heterocycle may be replaced by C(=0), C(=S), C(=CR*R*) and C=NR*, * indicates integers.

The term“non-aromatic heterocycle” or“non-aromatic heterocyclic” means three- to fifteen-membered, preferably three- to twelve-membered, saturated or partially unsaturated heterocycle containing one to four heteroatoms from the group of oxygen, nitrogen and sulphur: mono, bi- or tricyclic heterocycles which contain, in addition to carbon ring members, one to three nitrogen atoms and/or one oxygen or sulphur atom or one or two oxygen and/or sulphur atoms; if the ring contains more than one oxygen atom, they are not directly adjacent; for example (but not limited to) oxetanyl, oxiranyl, aziridinyl, 2-tetrahydrofuranyl, 3-tetrahydrofuranyl, 2-tetrahydrothienyl, 3-tetrahydrothienyl, 1-pyrrolidinyl, 2-pyrrolidinyl, 3-pyrrolidinyl, 3-isoxazolidinyl, 4-isoxazolidinyl, 5-isoxazolidinyl, 3-isothiazolidinyl, 4-isothiazolidinyl, 5-isothiazolidinyl, 1-pyrazolidinyl, 3-pyrazolidinyl, 4-pyrazolidinyl, 5-pyrazolidinyl, 2-oxazolidinyl, 4-oxazolidinyl, 5-oxazolidinyl, 2-thiazolidinyl, 4-thiazolidinyl, 5-thiazolidinyl, 1-imidazolidinyl, 2-imidazolidinyl, 4-imidazolidinyl, l,2,4-oxadiazolidin-3-yl, l,2,4-oxadiazolidin-5-yl, l,2,4-thiadiazolidin-3-yl, l,2,4-thiadiazolidin-5-yl, 1,2,4-triazolidin-l-yl, l,2,4-triazolidin-3-yl, 1,3,4-oxadiazolidin-2-yl, l,3,4-thiadiazolidin-2-yl, 1,3,4-triazolidin-l-yl, l,3,4-triazolidin-2-yl, 2,3-dihydrofur-2-yl, 2,3-dihydrofur-3-yl, 2,4-dihydrofur-2-yl, 2,4-dihydrofur-3-yl, 2,3-dihydrothien-2-yl, 2,3-dihydrothien-3-yl, 2,4-dihydrothien-2-yl, 2,4-dihydrothien-3-yl, pyrrolinyl, 2-pyrrolin-2-yl, 2-pyrrolin-3-yl, 3-pyrrolin-2-yl, 3-pyrrolin-3-yl, 2-isoxazolin-3-yl, 3-isoxazolin-3-yl, 4-isoxazolin-3-yl, 2-isoxazolin-4-yl, 3-isoxazolin-4-yl, 4-isoxazolin-4-yl, 2-isoxazolin-5-yl, 3-isoxazolin-5-yl, 4-isoxazolin-5-yl, 2-isothiazolin-3-yl, 3-isothiazolin-3-yl, 4-isothiazolin-3-yl, 2-isothiazolin-4-yl, 3-isothiazolin-4-yl, 4-isothiazolin-4-yl, 2-isothiazolin-5-yl, 3-isothiazolin-5-yl, 4-isothiazolin-5-yl, 2,3-dihydropyrazol-l-yl, 2,3-dihydropyrazol-2-yl, 2,3-dihydropyrazol-3-yl, 2,3-dihydropyrazol-4-yl, 2,3-dihydropyrazol-5-yl, 3,4-dihydropyrazol-l-yl, 3,4-dihydropyrazol-3-yl, 3,4-dihydropyrazol-4-yl, 3,4-dihydropyrazol-5-yl, 4,5-

dihydropyrazol-l-yl, 4,5-dihydropyrazol-3-yl, 4,5-dihydropyrazol-4-yl, 4,5-dihydropyrazol-5-yl, 2,3-dihydrooxazol-2-yl, 2,3-dihydrooxazol-3-yl, 2,3-dihydrooxazol-4-yl, 2,3-dihydrooxazol-5-yl, 3,4-dihydrooxazol-2-yl, 3,4-dihydrooxazol-3-yl, 3,4-dihydrooxazol-4-yl, 3,4-dihydrooxazol-5-yl, 3,4-dihydrooxazol-2-yl, 3,4-dihydrooxazol-3-yl, 3,4-dihydrooxazol-4-yl, piperidinyl, 2-piperidinyl, 3-piperidinyl, 4-piperidinyl, pyrazynyl, morpholinyl, thiomorphlinyl, l,3-dioxan-5-yl, 2-tetrahydropyranyl, 4-tetrahydropyranyl, 2-tetrahydrothienyl, 3-hexahydropyridazinyl, 4-hexahydropyridazinyl, 2-hexahydropyrimidinyl, 4-hexahydropyrimidinyl, 5-hexahydropyrimidinyl, 2-piperazinyl, 1,3,5-hexahydrotriazin-2-yl, l,2,4-hexahydrotriazin-3-yl, cycloserines, 2,3,4,5-tetrahydro[lH]azepin-l- or -2- or -3- or -4- or -5- or -6- or -7- yl, 3,4,5,6-tetra-hydro[2H]azepin-2- or -3- or -4- or -5- or -6- or-7-yl, 2, 3,4,7-tetrahydro[lH]azepin-l- or -2- or -3- or -4- or -5- or -6- or-7- yl, 2,3,6,7-tetrahydro[lH]azepin-l- or -2- or -3- or -4- or -5- or -6- or -7- yl, hexahydroazepin-1- or -2- or -3- or -4- yl, tetra- and hexahydrooxepinyl such as 2,3,4,5-tetrahydro[l H]oxepin-2- or -3- or -4- or -5- or -6- or -7- yl, 2,3,4,7-tetrahydro[lH]oxepin-2- or -3- or -4- or -5- or -6- or -7- yl, 2,3,6,7-tetrahydro[lH]oxepin-2- or -3- or -4- or -5- or -6- or -7- yl, hexahydroazepin-1- or -2- or -3- or -4- yl, tetra- and hexahydro-l,3-diazepinyl, tetra- and hexahydro-1,4-diazepinyl, tetra- and hexahydro-l,3-oxazepinyl, tetra- and hexahydro-l,4-oxazepinyl, tetra- and hexahydro-1, 3-diox epinyl, tetra- and hexahydro-l,4-dioxepinyl. This definition also applies to heterocyclyl as a part of a composite substituent, for example heterocyclylalkyl etc., unless specifically defined elsewhere.

The term“trialkylsilyl” includes 3 branched and/or straight-chain alkyl radicals attached to and linked through a silicon atom such as trimethylsilyl, triethylsilyl and t-butyl-dimethylsilyl. The term “halotrialkylsilyl” denotes at least one of the three alkyl radicals is partially or fully substituted with halogen atoms which may be the same or different. The term“alkoxytrialkylsilyl” denotes at least one of the three alkyl radicals is substituted with one or more alkoxy radicals which may be the same or different. The term“trialkylsilyloxy” denotes a trialkylsilyl moiety attached through oxygen.

Non limiting examples of “alkylcarbonyl” include C(0)CH3, C(0)CH2CH2CH3 and C(0)CH(CH3)2. Examples of “alkoxycarbonyl” include CH30C(=0), CH3CH20C(=0), CH3CH2CH20C(=0),

(CH3)2CH0C(=0) and the different butoxy -or pentoxycarbonyl isomers. Examples of ‘‘ alky laminoc arbony G’ include CH3NHC(=0), CH3CH2NHC(=0), CH3CH2CH2NHC(=0), (CH3)2CHNHC(=0) and the different butylamino -or pentylaminocarbonyl isomers. Non limiting examples of“dialkylaminocarbonyl” include (CH3)2NC(=0), (CH3CH2)2NC(=0), CH3CH2(CH3)NC(=0), CH3CH2CH2(CH3)NC(=0) and (CH3)2CHN(CH3)C(=0). Examples of “alkoxyalkylcarbonyl” include CH30CH2C(=0), CH30CH2CH2C(=0), CH3CH20CH2C(=0), CH3CH2CH2CH20CH2C(=0) and

CH3CH20CH2CH2C(=0). Non limiting examples of “alkylthioalkylcarbonyl” include CH3SCH2C(=0),

CH3SCH2CH2C(=0), CH3CH2SCH2C(=0), CH3CH2CH2CH2SCH2C(=0) and CH3CH2SCH2CH2C(=0). The term haloalkylsufonylaminocarbonyl, alkylsulfonylaminocarbonyl, alkylthioalkoxycarbonyl, alkoxycarbonylalkyl amino and the like are defined analogously

Non limiting examples of“alkylaminoalkylcarbonyF’ include CH3NHCH2C(=0), CH3NHCH2CH2C(=0), CH3CH2NHCH2C(=0), CH3CH2CH2CH2NHCH2C(=0) and CH3CH2NHCH2CH2C(=0).

The term“amide” means A-R'C=ONR"-B, wherein R' and R" indicates substituents and A and B indicate any group.

The term“thioamide” means A-R'C=SNR"-B, wherein R' and R" indicates substituents and A and B indicate any group.

The total number of carbon atoms in a substituent group is indicated by the“Ci-Cj” prefix where i and j are numbers from 1 to 21. For example, Ci-C3 alkylsulfonyl designates methylsulfonyl through propylsulfonyl; C2 alkoxyalkyl designates CH3OCH2; C3 alkoxyalkyl designates, for example, CH3CH(OCH3), CH3OCH2CH2 or CH3CH2OCH2; and A alkoxyalkyl designates the various isomers of an alkyl group substituted with an alkoxy group containing a total of four carbon atoms, examples including CH3CH2CH2OCH2 and CH3CH2OCH2CH2. In the above recitations, when a compound of Formula I is comprised of one or more heterocyclic rings, all substituents are attached to these rings through any available carbon or nitrogen by replacement of a hydrogen on said carbon or nitrogen.

When a compound is substituted with a substituent bearing a subscript that indicates the number of said substituents can exceed 1, said substituents (when they exceed 1) are independently selected from the group of defined substituents. Further, when the subscript m in (R)m indicates an integer ranging from for example 0 to 4 then the number of substituents may be selected from the integers between 0 and 4 inclusive.

When a group contains a substituent which can be hydrogen, then, when this substituent is taken as hydrogen, it is recognized that said group is being un-substituted.

The embodiments herein and the various features and advantageous details thereof are explained with reference to the non-limiting embodiments in the description. Descriptions of well-known components and processing techniques are omitted so as to not unnecessarily obscure the embodiments herein. The examples used herein are intended merely to facilitate an understanding of ways in which the embodiments herein may be practiced and to further enable those of skilled in the art to practice the embodiments herein. Accordingly, the examples should not be construed as limiting the scope of the embodiments herein.

The description of the specific embodiments will so fully reveal the general nature of the embodiments herein that others can, by applying current knowledge, readily modify and/or adapt for various applications such specific embodiments without departing from the generic concept, and, therefore, such adaptations and modifications should and are intended to be comprehended within the meaning and range of equivalents of the disclosed embodiments. It is to be understood that the phraseology or terminology employed herein is for the purpose of description and not of limitation. Therefore, while the embodiments herein have been described in terms of preferred embodiments, those skilled in the art will recognize that the embodiments herein can be practiced with modification within the spirit and scope of the embodiments as described herein.

Any discussion of documents, acts, materials, devices, articles and the like that has been included in this specification is solely for the purpose of providing a context for the disclosure. It is not to be taken as an admission that any or all of these matters form a part of the prior art base or were common general knowledge in the field relevant to the disclosure as it existed anywhere before the priority date of this application.

The numerical values mentioned in the description and the description/claims though might form a critical part of the present invention of the present invention, any deviation from such numerical values shall still fall within the scope of the present invention if that deviation follows the same scientific principle as that of the present invention disclosed in the present invention. The inventive compounds of the present invention may, if appropriate, be present as mixtures of different possible isomeric forms, especially of stereoisomers, for example E and Z, threo and erythro, and also optical isomers, but if appropriate also of tautomers. Both the E and the Z isomers, and also the threo and erythro isomers, and the optical isomers, any desired mixtures of these isomers and the possible tautomeric forms are disclosed and claimed.

The term “pest” for the purpose of the present disclosure includes but is not limited to fungi, stramenopiles (oomycetes), bacteria, nematodes, mites, ticks, insects and rodents.

The term“plant” is understood here to mean all plants and plant populations, such as desired and undesired wild plants or crop plants (including naturally occurring crop plants). Crop plants may be plants which can be obtained by conventional breeding and optimization methods or by biotechnological and genetic engineering methods or combinations of these methods, including the transgenic plants and including the plant cultivars which are protectable and non-protectable by plant breeders’ rights.

For the purpose of the present disclosure the term“plant” includes a living organism of the kind exemplified by trees, shrubs, herbs, grasses, ferns, and mosses, typically growing in a site, absorbing water and required substances through its roots, and synthesizing nutrients in its leaves by photosynthesis.

Examples of “plant” for the purpose of the present invention include but are not limited to agricultural crops such as wheat, rye, barley, triticale, oats or rice; beet, e.g. sugar beet or fodder beet; fruits and fruit trees, such as pomes, stone fruits or soft fruits, e.g. apples, pears, plums, peaches, almonds, cherries, strawberries, raspberries, blackberries or gooseberries; leguminous plants, such as lentils, peas, alfalfa or soybeans; oil plants, such as rape, mustard, olives, sunflowers, coconut, cocoa beans, castor oil plants, oil palms, ground nuts or soybeans; cucurbits, such as squashes, cucumber or melons; fiber plants, such as cotton, flax, hemp or jute; citrus fruit and citrus trees, such as oranges, lemons, grapefruits or mandarins; any horticultural plants, vegetables, such as spinach, lettuce, asparagus, cabbages, carrots, onions, tomatoes, potatoes, cucurbits or paprika; lauraceous plants, such as avocados, cinnamon or camphor; cucurbitaceae; oleaginous plants; energy and raw material plants, such as cereals, corn, soybean, other leguminous plants, rape, sugar cane or oil palm; tobacco; nuts; coffee; tea; cacao; bananas; peppers; vines (table grapes and grape juice grape vines); hop; turf; sweet leaf (also called Stevia); natural rubber plants or ornamental and forestry plants, such as flowers, shrubs, broad-leaved trees or evergreens, e.g. conifers; and on the plant propagation material, such as seeds, and the crop material of these plants.

Preferably, the plant for the purpose of the present invention include but is not limited to cereals, corn, rice, soybean and other leguminous plants, fruits and fruit trees, grapes, nuts and nut trees, citrus and citrus trees, any horticultural plants, cucurbitaceae, oleaginous plants, tobacco, coffee, tea, cacao, sugar beet, sugar cane, cotton, potato, tomato, onions, peppers and vegetables, ornamentals, any floricultural plants and other plants for use of human and animals.

The term“plant parts” is understood to mean all parts and organs of plants above and below the ground. For the purpose of the present disclosure the term plant parts includes but is not limited to cuttings, leaves, twigs, tubers, flowers, seeds, branches, roots including taproots, lateral roots, root hairs, root apex, root cap, rhizomes, slips, shoots, fruits, fruit bodies, bark, stem, buds, auxiliary buds, meristems, nodes and internodes.

The term“locus thereof’ includes soil, surroundings of plant or plant parts and equipment or tools used before, during or after sowing/planting a plant or a plant part.

Application of the compounds of the present disclosure or the compound of the present disclosure in a composition optionally comprising other compatible compounds to a plant or a plant material or locus

thereof include application by a technique known to a person skilled in the art which include but is not limited to spraying, coating, dipping, fumigating, impregnating, injecting and dusting.

The term“applied” means adhered to a plant or plant part either physically or chemically including impregnation.

The present invention relates to a compound of formula (I),

The definition of each componenent of Formula I is provided herein below in detail.

R1 is NR10RU.

The substituent R10 is selected from the group consisting of hydrogen, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, C3-C6 halocycloalkyl, Ci-Ce alkoxy and Ci-Ce haloalkoxy.

Particularly, the substituent R10 is selected from the group consisting of hydrogen, C1-C4 alkyl, C3-C8 cycloalkyl, and C3-C8 cycloalkyl-Ci-Ce alkyl.

The substituent R11 is a 5-, 6- or 7- membered heterocyclyl ring attached to N of R1 through C atom; said heterocyclyl ring comprises one or two hetero atoms selected from N, O or S; and one or more C of the heterocyclyl ring may be optionally replaced with C(=0) or C(=S) or C(=NR19); said heterocyclyl ring may be optionally substituted with one or more R16a.

Particularly, the substituent R11 is a 5- membered heterocyclyl ring attached to N of R1 through C atom; said heterocyclyl ring comprises two hetero atoms selected from N and O; and one or more C of the heterocyclyl ring may be optionally replaced with C(=0); said heterocyclyl ring may be optionally substituted with one or more R16a.

More particularly, the substituent R11 is selected from the group consisting of

Most particularly, R1 1 is selected from the group consisting of:

The substituents R 1 (a and R16b is selected from the group of consisting of hydrogen, halogen, cyano, nitro, hydroxy, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy-Ci-Ce alkyl, Ci-Ce hydroxyalkyl, C2-C6 haloalkenyl, C2-C6 haloalkynyl, C3-C6 halocycloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce haloalkoxycarbonyl, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce haloalkylsulfinyl, Ci-Ce haloalkylsulfonyl, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulfonyl, C 1 -Cr, alkylamino, Ci-Ce dialkylamino, C3-C6 cycloalkylamino, Ci-Ce alkyl-C3-C6-cycloalkylamino, Ci-Cr, alkylcarbonyl, Ci-Ce alkoxycarbonyl, Ci-Ce alkylaminocarbonyl, Ci-Ce dialkylaminocarbonyl, Ci-Ce alkoxycarbonyloxy, Ci-Ce alkylaminocarbonyloxy, Ci-Ce dialkylaminocarbonyloxy and Ci-Ce trialkylsilyl. The substituent R16a and R16b may be optionally further substituted with Ci-Ce alkyl, C3-C8 cycloalkyl, Ci-Ce alkoxy, and C Cr, alkoxy-Ci-Ce alkyl.

Particularly, the substituent R16a is selected from the group consisting of hydrogen, halogen, Ci-Ce alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy-Ci-Ce alkyl, Ci-Ce alkylcarbonyl and Ci-Ce alkylsulfonyl.

W1 and W2 are independently O or S. Particularly, W1 and W2 are O.

Two R3 substituents together with the carbon atoms to which they are attached may form a 5- to 11-membered carbocycle, or aryl or heterocyclyl or heteroaryl ring or ring system which may be optionally substituted with R2.

The substituents R2 and R3 are independently selected from the group consisting of hydrogen, halogen, cyano, nitro, hydroxy, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, C 1 -Cr, haloalkyl, C 1 -Cr, alkoxy-Ci-Ce alkyl, Ci-Ce hydroxyalkyl, C2-C6 haloalkenyl, C2-C6 haloalkynyl, C3-C6 halocycloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce haloalkoxycarbonyl, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce haloalkylsulfinyl, Ci-Ce haloalkylsulfonyl, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulfonyl, Ci-Ce alkylamino, Ci-Ce dialkylamino, C3-C6 cycloalkylamino, Ci-Ce alkyl-C3-Ce-cycloalkylamino, Ci-Ce alkylcarbonyl, Ci-Ce alkoxycarbonyl, Ci-Ce alkylaminocarbonyl, Ci-Ce dialkylaminocarbonyl, Ci-Ce alkoxycarbonyloxy, Ci-Ce alkylaminocarbonyloxy, Ci-Ce dialkylaminocarbonyloxy, Ci-Ce trialkylsilyl, amino, formyl, C2-C6 cyanoalkenyl, phenylcarbonylamino and phenyloxycarbonyl; wherein each of R2 and R3 may optionally be substituted with halogen, cyano, nitro, hydroxy, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy-Ci-Ce alkyl, Ci-Ce hydroxyalkyl, C2-C6 haloalkenyl, C2-C6 haloalkynyl, C3-Ce halocycloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce haloalkylsulfinyl, Ci-Ce haloalkylsulfonyl, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulfonyl, Ci-Ce alkylamino, C 1 -Cr, dialkylamino, C3-C6 cycloalkylamino, Ci-Ce alkyl-C3-C6 cycloalkylamino, Ci-Ce alkylcarbonyl, Ci-Ce alkoxycarbonyl, Ci-Ce alkylaminocarbonyl, Ci-Ce dialkylaminocarbonyl, Ci-Ce alkoxycarbonyloxy, Ci-Ce alkylaminocarbonyloxy, Ci-Ce dialkylaminocarbonyloxy and Ci-Ce trialkylsilyl.

Alternatively, the substituents R2 and R3 are independently selected from the group consisting of phenyl, benzyl, phenoxy or 4- to 6- heterocyclyl; each phenyl, benzyl, phenoxy or 4- to 6- heterocyclyl may optionally be substituted with one or more substituent selected from halogen, cyano, nitro, hydroxy, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl -Ci-Ce alkyl, C 1 -Cr, haloalkyl, Ci-Ce alkoxy-Ci -Cr, alkyl, C 1 -Cr, hydroxyalkyl, C2-C6 haloalkenyl, C2-C6 haloalkynyl, C3-C6 halocycloalkyl, C 1 -Cr, alkoxy, Ci -Cr, alkylthio, C 1 -Cr, haloalkylthio, C 1 -Cr, haloalkylsulfinyl, Ci -Cr, haloalkylsulfonyl, Ci-Ce alkylsulfinyl, C 1 -Cr, alkylsulfonyl, C 1 -Cr, alkylamino, C 1 -Cr, dialkylamino, C3-C6 cycloalkylamino, Ci-Ce alkyl-C3-C6-cycloalkylamino, C 1 -Cr, alkylcarbonyl, C 1 -Cr, alkoxycarbonyl, C 1 -Cr, alkylaminocarbonyl, C 1 -Cr, dialkylaminocarbonyl, C 1 -Cr, alkoxycarbonyloxy, C 1 -Cr, alkylaminocarbonyloxy, C 1 -Cr, dialkylaminocarbonyloxy, C 1 -Cr, trialkylsilyl, 2-, 3- or 4 pyridylcarbonylamino which can be mono-, di-or tri- substituted by halogen, cyano, nitro, hydroxy, Ci -Cr, alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl-Ci -Cr, alkyl, C3-C8 cycloalkyl-Ci -Cr, alkyl, C 1 -Cr, haloalkyl, C 1 -Cr, alkoxy-Ci -Cr, alkyl, C 1 -Cr, hydroxyalkyl, CVCr, haloalkenyl, CVCr, haloalkynyl, C3-C6 halocycloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce haloalkylsulfinyl. Ci-Ce haloalkylsulfonyl, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulfonyl, Ci-Ce alkylamino, Ci-Ce dialkylamino, C3-C6 cycloalkylamino, Ci-Ce alkyl-C3-C6 cycloalkylamino, Ci-Ce alkylcarbonyl, Ci-Ce alkoxycarbonyl, Ci-Ce alkylaminocarbonyl, Ci-Cr, dialkylaminocarbonyl, Ci-Ce alkoxycarbonyloxy, Ci-Ce alkylaminocarbonyloxy, Ci-Ce dialkylaminocarbonyloxy, Ci-Ce trialkylsilyl, Ci-Ce alkoxycarbonylamino, Ci-Ce alkylaminocarbonylamino, CV C r, d i a I k y I a m i n oc a r bo n y I a m i n o , Ci-Cehaloalkylcarbonyl and RxON=C(Ry). Rx and Ry independently are hydrogen or CVCr, alkyl.

Particularly, R3 is selected from the group consisting of hydrogen, halogen, cyano, nitro, hydroxy, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, CVCr, alkyl-C3-Cs, cycloalkyl, Ci-Ce haloalkyl, CVCr, alkoxy, CVCr, haloalkoxy, CVCr, alkylthio and CVCr, haloalkylthio.

More particularly, the substituent R3 is selected from the group consisting of hydrogen, halogen, cyano and C1-C4 alkyl.

The integer“m” is ranging from 0 to 4. Particularly, the integer“m” is ranging from 0 to 2.

The substituent R4 is selected from the group consisting of hydrogen, C i -Cr, alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C i -Cr, alkylcarbonyl and C i -Cr, alkoxycarbonyl; each of C i -Cr, alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, Ci-Ce alkylcarbonyl, Ci-Ce alkoxycarbonyl may optionally be substituted by one or more substituents selected from halogen nitro, cyano, hydroxy, C i -Cr, alkoxy, C i -Cr, haloalkoxy, C i -Cr, alkylthio, C i -Cr, haloalkylthio, C i -Cr, alkylsulfinyl, C i -Cr, alkylsulfonyl, C i -Cr, alkylamino, C i -Cr, dialkylamino, C3-C8 cycloalkyl, C3-C6 cycloalkylamino and Ci-Cr, alkyl-C3-C6 cycloalkylamino.

Particularly, the substituent R4 is selected from the group consisting of hydrogen, C i -Cr, alkyl and C3-C8 cycloalkyl. More particularly, the substituent R4 is hydrogen.

D is selected from the group consisting of;

wherein;

the bond on the right is attached to Z1 and the bond on the left is attached to carbon marked with 2; or the bond on the right is attached to Z1 and the bond on the left is attached to carbon marked with 2.

Particularly, D is D4 and the bond on the right is attached to Z1 and the bond on the left is attached to

carbon marked with 2. More particularly, D is 1 4-1 wherein;

the bond on the right is attached to Z1 and the bond on the left is attached to carbon marked with 2.

The substituents R8 and R9 may be attached to one or more possible position/s.

The substituent R8 is selected from the group consisting of hydrogen, Ci-Ce alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci -Cr, alkyl, Ci-Ce haloalkyl, halogen, cyano, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkoxycarbonyl, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulfonyl, Ci-Ce haloalkylsulfinyl and Ci-Ce haloalkylsulfonyl.

Particularly, the substituent R8 is selected from the group consisting of hydrogen, C1-C4 alkyl, C3-C5 cycloalkyl, halogen, cyano, C1-C4 alkoxy, C1-C4 haloalkoxy and C1-C4 alkylthio. More particularly, the substituent R8 is hydrogen.

The substituent R9 is selected from a phenyl ring, a benzyl ring, a 5- or 6-membered aromatic or heteroaromatic ring, a naphthyl ring system, an 8-, 9- or 10-membered fused heterobicyclic ring system, each ring or ring system optionally substituted with at least one substituent independently selected from the group consisting of halogen, Ci-Ce alkyl, C2-C4 alkenyl, C2-C4 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci -Cr, alkyl, C 1 -Cr, haloalkyl, C2-C4 haloalkenyl, C2-C4 haloalkynyl, C3-C6 halocycloalkyl, cyano, nitro, C 1 -Cr, alkoxy, C 1 -Cr, haloalkoxy, Ci -Cr, alkoxycarbonyl, C 1 -Cr, alkylthio, C 1 -Cr, haloalkylthio, C 1 -Cr, alkylsulfinyl, Ci -Cr, alkylsulfonyl, C 1 -Cr, haloalkylsulfinyl, C 1 -Cr, haloalkylsulfonyl, C 1 -Cr, alkylamino, Ci-Cs dialkylamino, C 1 -Cr, cycloalkylamino, C3-C8 c y c I ( ) a I k y I - C 1 - C r, - a I k I y a m i n ( ) , C 1 -Cr, alkylcarbonyl, C 1 -Cr, alkoxycarbonyl, C 1 -Cr, alkylaminocarbonyl, Ci-Cs dialkylaminocarbonyl and C 1 -Cr, trialkylsilyl.

Particularly, the substituent R9 is selected from a phenyl ring, a benzyl ring, a 5- or 6-membered heteroaromatic ring, each ring or ring system optionally substituted with one or more substituent independently selected from the group consisting of halogen, C 1 -Cr, alkyl, C 1 -Cr, haloalkyl, cyano and nitro. More particularly, the substituent R9 is a 5- or 6-membered heteroaromatic ring optionally substituted with one or more halogen.

7} is a direct bond or CR6R7 or C(O) or NR18 or O or S(0)o-2- Particularly, Z1 is a direct bond or CR6R7 or or O.

The substituents R6 and R7 are independently selected from the group consisting of hydrogen, halogen, cyano, hydroxy, formyl, C 1 -Cr, alkyl, C2-C4 alkenyl, C2-C4 alkynyl, Ci -Cr, haloalkyl, C2-C4 haloalkenyl, C2-C4 haloalkynyl, C 1 -Cr, alkoxy-C Cr, alkyl, C 1 -Cr, alkylthioalkyl, C 1 -Cr, alkylsulfinylalkyl, C 1 -Cr, alkylsulfonylalkyl, C 1 -Cr, alkylcarbonyl, C 1 -Cr, haloalkylcarbonyl, C 1 -Cr, alkoxycarbonyl, C 1 -Cr,

alkoxycarbonyl-Ci-Ce -alkyl, Ci-Ce alkylaminocarbonyl, C1-C5 dialkylaminocarbonyl, Ci-Ce alkoxy, Ci-Cr, haloalkoxy, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Cr, alkyl, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Cr, alkylsulfinyl, Ci-Ce haloalkylsulfinyl, Ci-Ce alkylsulfonyl and Ci-Ce haloalkylsulfonyl.

Particularly, the substituents R6 and R7 are independently selected from the group consisting of hydrogen, halogen, cyano, hydroxy, formyl, C1-C4 alkyl and C1-C4 haloalkyl.

The substituents R18 and R19 is selected from the group consisting of hydrogen, halogen, cyano, hydroxy, formyl, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, Ci-Cr, alkoxy-Ci-Ce alkyl, Ci-Ce hydroxyalkyl, C2-C6 haloalkenyl, C2-C6 haloalkynyl, C3-C6 halocycloalkyl, Ci-Ce alkoxy, C 1 -Cr, haloalkoxy, C 1 -CVal kylcarbony I, Ci-Ce haloalkoxycarbonyl, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce haloalkylsulfinyl, Ci-Ce haloalkylsulfonyl, Ci-Ce alkylsulfinyl and C 1 -Cr, alkylsulfonyl.

E is selected from the group consisting of hydrogen, halogen, cyano, Ci-Cr, alkyl, C3-C6 cycloalkyl, C3-C8 cycloalkyl-Ci -Cr, alkyl, Ci-Cr, haloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy and C3-C6 heterocyclyl; said heterocyclyl ring comprise one or more hetero atoms selected from N, O and S(0)o-2; and one or more C of the heterocyclyl ring or ring system may be replaced with C(=0), C(=S) or C(=NR19); said heterocyclyl ring may be optionally substituted with one or more R16b.

Particularly, E is selected from the group consisting of hydrogen, halogen, cyano, Ci-Ce alkyl, C3-C6 cycloalkyl, C3-C8 cycloalkyl-Ci-Cr, alkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy and C3-C6 heterocyclyl; said heterocyclyl ring comprise one or more hetero atoms selected from N, O and S(0)o-2; and one or more C of the heterocyclyl ring or ring system may be replaced with C(=0), C(=S) or C(=NR19); said heterocyclyl ring may be optionally substituted with one or more substituents selected from the group consisting of hydrogen, halogen, cyano and nitro.

More particularly, E is selected from the group consisting of halogen, cyano, Ci-Ce alkyl, C3-C6 cycloalkyl, C3-C8 cycloalkyl-Ci-Cr, alkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy and C3-C6 heterocyclyl; said heterocyclyl ring comprise one or more hetero atoms selected from N, O and S(0)o-2; said heterocyclyl ring may be optionally substituted with one or more halogen.

Alternatively, E is selected from 5- or 6- membered aromatic or heteroaromatic ring or an 8-, 9- or 10-membered heterobicyclic ring systems; wherein the heteroatoms in heteroaromatic ring may be selected from N, O, and S ; wherein the heteroatoms in the heterobicyclic ring systems may be selected from N, O and S(0)o-2; and C atom of the heterobicyclic ring system may be replaced with C(=0), C(=S) or C(=NR19); wherein the aromatic, heteroaromatic or heterobicyclic ring or the ring system may be optionally substituted with hydrogen, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci -Cr, alkyl, C 1 -Cr, haloalkyl, C2-C e haloalkenyl, C2-C6 haloalkynyl, C3-C6 halocycloalkyl, halogen, cyano, carboxyl, aminocarboxyl nitro, hydroxy, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkylthio, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulphonyl, C Cr, haloalkylthio, Ci-Ce haloalkylsulfinyl, Ci-Ce haloalkylsulfonyl, phenyl or a 5- or 6- membered heteroaromatic ring; wherein said phenyl or the heteroaromatic ring is optionally substituted with at least one group selected from Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Cr, alkyl, Ci-Ce haloalkyl, C2- Cr, haloalkenyl, C2-C6 haloalkynyl, C3-C6 halocycloalkyl, halogen, cyano, carboxyl, aminocarboxyl nitro, hydroxy, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkylthio, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulphonyl, Ci-Cr, haloalkylthio, Ci-Ce haloalkylsulfinyl or Ci-Ce haloalkylsulfonyl.

Particularly, E is 5- or 6- membered heteroaromatic ring, wherein the heteroatoms in heteroaromatic ring may be selected from one or more N, O and S; and heteroaromatic ring may be optionally substituted with hydrogen, Ci-Ce alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Cr, alkyl, Ci-Ce haloalkyl, C3- Cr, halocycloalkyl, halogen, cyano, carboxyl, aminocarboxyl, nitro, hydroxy, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkylthio, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulphonyl, Ci-Ce haloalkylthio, Ci-Ce haloalkylsulfinyl and Ci-Ce haloalkylsulfonyl.

The present invention also relates to the salts, metal complexes, N-oxides, isomers or polymorphs of compound of formula (I).

The compounds selected from l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((4,5-dihydrothiazol-2-yl)carbamoyl)-6-methylphenyl)-3-((5-(perfluoroethyl)-2H-tetrazol-2-yl)methyl)-lH-pyr azole-5-carboxamide; N-(4-chloro-2-((4,5-dihydrothiazol-2-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-((5-(perfluoroethyl)-2H-tetrazol-2-yl)methyl)-lH-pyrazole-5-carboxamide; l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((4,5-dihydrothiazol-2-yl)carbamoyl)-6-methylphenyl)-3-((5-(trifluoromethyl)-2H-tetrazol-2-yl)methyl)-lH-pyrazole-5-carboxamide; and N-(4-chloro-2-((4,5-dihydrothiazol-2-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-((5-(trifluoromethyl)-2H-tetrazol-2-yl)methyl)-lH-pyrazole-5-carboxamide are excluded from the definition of formula (I).

Particularly, the compound of formula (I) is selected from 3-bromo-N-(4-chloro-2-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide;

3-bromo-N-(4-chloro-2-methyl-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazobdin-4-yl)carbamoyl)phenyl)-l- (3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-((2-(cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-(cyclopropylmethyl)-3-oxoisoxazobdin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-methyl-6-((3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-ethyl-3-oxoisoxazolidin- 4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-(cyclopropylmethyl)-3-oxoisoxazobdin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-(2,2-difluoroethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-(2,2-difluoroethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-(cyclopropylmethyl)- 3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-methyl-6-((l-methyl-3-oxopyrazobdin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((l-methyl-3-oxopyrazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((l-methyl-3-oxopyrazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5 -carboxamide; 3-bromo-N-(4-chloro-2-((2-(2,2-difluoroethyl)-3-oxoisoxazolidin- 4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((l-methyl-3-oxopyrazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-((2-(2-ethoxyethyl)-3-oxoisoxazobdin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-methyl-3-oxoisoxazobdin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5- carboxamide; 3 -bromo- 1 -(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-(( 1 -methyl-3-oxopyrazolidin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-(methylsulfonyl)isoxazolidin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5 -carboxamide; 3-bromo-N-(4-chloro-2-methyl-6-((2-(methylsulfonyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5 -carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2- (methylsulfonyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-(methylsulfonyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-(ethylsulfonyl)isoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-((2-(ethylsulfonyl)isoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2- (ethylsulfonyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-(ethylsulfonyl)isoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-((2-acetylisoxazolidin-4-yl)carbamoyl)-6-bromo-4-chlorophenyl)-3-bromo-l-(3-chloropyridin-2-yl)-lH-pyrazole-5 -carboxamide; N-(2-((2-acetylisoxazolidin-4-yl)carbamoyl)-4-chloro-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5 -carboxamide; N-(2-((2-acetylisoxazolidin-4-yl)carbamoyl)-4-chloro-6-methylphenyl)-3-bromo-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(2-((2-acetylisoxazolidin-4-yl)carbamoyl)-4-chloro-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-((2-acetylisoxazolidin-4-yl)carbamoyl)-4-cyano-6-methylphenyl)-3-bromo-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-propionylisoxazolidin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-propionylisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-propionylisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-propionylisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5 -carboxamide; 3-bromo-N-(4-chloro-2-methyl-6-((2-propionylisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-(methylsulfonyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3 -chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-(ethylsulfonyl)isoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l -(3 -chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5 -carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5 -carboxamide; N-(4-chloro-2-((2-isopropyl-3-

oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyri din-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2- (cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-(cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-lH-pyr azole-5-carboxamide; N-(2-bromo-4-chloro-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5 -carboxamide; N-(2-bromo-4-chloro-6-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(2-bromo-4-

chloro-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((3-oxo-2-(2,2,2-trifhioroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-(cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole- 5-carboxamide; N-(2-bromo-4-chloro-6-((2-(cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((3-oxo-2-(2,2,2-trifbioroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)- 1 H-pyrazole-5 -carboxamide; 3-bromo- 1-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-(cyclopropylmethyl)-3-oxoisoxazobdin-4-yl)carbamoyl)-6-methylphenyl)-lH-pyrazole-5-carboxamide; rac-(R)-3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-lH-pyrazole-5-carboxamide; rac-(R)-N-(2-bromo-4-chloro-6-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-1 H-pyrazole-5 -carboxamide; rac-(R)-N-(2-bromo-4-chloro-6-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; rac-(R)-N-(2-bromo-4-chloro-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; rac-(R)-N-(2-bromo-4-chloro- 6-((2-methyl-3-oxoisoxazobdin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; rac-(R)-3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; rac-(R)-3-bromo-N-(4-chloro-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; rac-(R)-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-3-(thietan-3-yloxy)-lH-pyrazole-5-carboxamide; rac-(R)-N-(4-chloro-2-methyl-6-((2-methyl-3-oxoisoxazobdin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; rac-(R)-3-bromo-N-(4-chloro-2-((2-ethyl-3-oxoisoxazobdin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5 -carboxamide; rac-(R)-N-(4-chloro-2-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; rac-(R)-3-bromo-N-(4-chloro-2-methyl-6-((3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; rac-(R)-3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((3-oxoisoxazobdin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-3-methoxy-1 H-pyrazole-5 -carboxamide; l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-isopropyl-3-

oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-3-methoxy-lH-pyrazole-5-carboxamide; l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-3-(2,2,2-trifluoroethoxy)-lH-pyr azole-5-carboxamide; l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-3 -(2,2, 2-trifhioroethoxy)-lFl-pyr azole-5 -carboxamide; 3 -bromo- 1 -(3-chloropyridin-2-yl)-N -(2,4-dichloro-6-((3 -oxoisoxazobdin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; l-(3-chloropyridin-2-yl)-N-(2,4-dichloro-6-((3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-3-(trifluoromethyl)-lH-pyrazole-5-carboxamide; rac-(R)-l-(3-chloropyridin-2-yl)-N-(2,4-dichloro-6-((3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-3-(3,3-difluoroazetidin-l-yl)-lH-pyrazole-5 -carboxamide and l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2- (cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-3-methoxy-lH-pyrazole-5-carboxamide.

The present invention also relates to compounds of Formulae la and lb;

wherein, R16 is N(R4)2 or nitro; W1, W2, D, R1, R3, R4 and m are as defined herein before.

The present invention also relates to a process for preparing the compounds of formula la, and lb.

The present invention further relates to a process for preparing compound of formula (I) comprising the steps of:

a) preparing compound of formula (i) by using any of the methods known in the prior art; and b) reacting compound of formula (i) with compound of formula (ii) to afford compound of formula I according to the reaction scheme as depicted below;

wherein, W1, W2, D, E, Z1, R1, R3, R4 and m are as defined herein before.

Compounds of the present invention can exist as one or more stereoisomers. The various stereoisomers include enantiomers, diastereomers, atropisomers and geometric isomers. One skilled in the art will appreciate that one stereoisomer may be more active and/or may exhibit beneficial effects when enriched relative to the other stereoisomer(s) or when separated from the other stereoisomer(s). Additionally, the skilled artisan knows how to separate, enrich, and/or to selectively prepare said stereoisomers. The compounds of the present invention may be present as a mixture of stereoisomers, individual stereoisomers or as an optically active form.

An anion part of the salt in case the compound of Formula I is a cationic or capable of forming a cation can be inorganic or organic. Alterntively, a cation part of the salt in case the compound of Formula I is an anionic or capable of forming anion can be inorganic or organic. Examples of inorganic anion part of the salt include but are not limited to chloride, bromide, iodide, fluoride, sulfate, phosphate, nitrate, nitrite, hydrogen carbonates, hydrogen sulfate. Examples of organic anion part of the salt include but are not limited to formate, alkanoates, carbonates, acetates, trifluoroacetate, trichloroacetate, propionate, glycolate, thiocyanate, lactate, succinate, malate, citrates, benzoates, cinnamates, oxalates, alkyl sulphates, alkylsulpho nates, ary lsulpho nates aryldisulphonates, alkylphosphonates, arylphospho nates, aryldiphosphonates, p-toluenesulphonate, and salicylate. Examples of inorganic cation part of the salt include but are not limited to alkali and alkaline earth metals. Examples of organic cation part of the salt include but are not limited to pyridine, methyl amine, imidazole, benzimidazole, hitidine, phosphazene, tetramethyl ammonium, tetrabutylammonium, choline and trimethylamine.

Metal ions in metal complexes of the compound of Formula I are especially the ions of the elements of the second main group, especially calcium and magnesium, of the third and fourth main group, especially aluminium, tin and lead, and also of the first to eighth transition groups, especially chromium, manganese, iron, cobalt, nickel, copper, zinc and others. Particular preference is given to the metal ions of the elements of the fourth period and the first to eighth transition groups. Here, the metals can be present in the various valencies that they can assume.

In one another embodiment of present invention discloses the compound of Formula I agriculturally acceptable salts, metal complexes, constitutional isomers, stereo-isomers, diastereoisomers, enantiomers, chiral isomers, atropisomers, conformers, rotamers, tautomers, optical isomers, polymorphs, geometric isomers, or N-oxides thereof composition with the excipient, inert carrier or any other essential ingredient such as surfactants, additives, solid diluents and liquid diluents.

Compounds selected from Formula I, (including all stereoisomers, N-oxides, and salts thereof), typically exist in more than one form, and Formula I thus includes all crystalline and non-crystalline forms of the compounds that Formula I represents. Non-crystalline forms include embodiments which are solids such as waxes and gums as well as embodiments which are liquids such as solutions and melts. Crystalline forms include embodiments which represent essentially a single crystal type and embodiments which represent a mixture of polymorphs (i.e. different crystalline types). The term“polymorph” refers to a particular crystalline form of a chemical compound that can crystallize in different crystalline forms, these forms having different arrangements and/or conformations of the molecules in the crystal lattice. Although polymorphs can have the same chemical composition, they can also differ in composition due to the presence or absence of co-crystallized water or other molecules, which can be weakly or strongly bound in the lattice. Polymorphs can differ in such chemical, physical and biological properties as crystal shape, density, hardness, color, chemical stability, melting point, hygroscopicity, suspensibility, dissolution rate and biological availability. One skilled in the art will appreciate that a polymorph of a compound represented by Formula I can exhibit beneficial effects (e.g., suitability for preparation of useful formulations, improved biological performance) relative to another polymorph or a mixture of polymorphs of the same compound represented by Formula I. Preparation and isolation of a particular polymorph of a compound represented by Formula I can be achieved by methods known to those skilled in the art including, for example, crystallization using selected solvents and temperatures.

The present invention also relates to a composition for controlling or preventing insect and mite pests. The composition comprises a biologically effective amount of the compound of Formula I and at least one additional component selected from the group consisting of surfactants and auxiliaries.

In one another embodiment of present invention relates a compound of Formula I or its N-oxides and salts into customary types of agrochemical compositions, e. g. solutions, emulsions, suspensions, dusts, powders, pastes, granules, pressings, capsules, and mixtures thereof. Examples for composition types are suspensions (e.g. SC, OD, FS), emulsifiable concentrates (e.g. EC), emulsions (e.g. EW, EO, ES, ME), capsules (e.g. CS, ZC), pastes, pastilles, wettable powders or dusts (e.g. WP, SP, WS, DP, DS), pressings (e.g. BR, TB, DT), granules (e.g. WG, SG, GR, FG, GG, MG), insecticidal articles (e.g. LN), as well as gel formulations for the treatment of plant propagation materials such as seeds (e.g. GF). These and further compositions types are defined in the“Catalogue of pesticide formulation types and international coding system”, Technical Monograph No. 2, 6th Ed. May 2008, CropLife International.

The compositions are prepared in a known manner, such as described by Mollet and Grubemann, Formulation technology, Wiley VCH, Weinheim, 2001 ; or Knowles, New developments in crop protection product formulation, Agrow Reports DS243, Tand F Informa, London, 2005.

Examples for suitable auxiliaries are solvents, liquid carriers, solid carriers or fillers, surfactants, dispersants, emulsifiers, wetters, adjuvants, solubilizers, penetration enhancers, protective colloids, adhesion agents, thickeners, humectants, repellents, attractants, feeding stimulants, compatibilizers, bactericides, anti-freezing agents, anti-foaming agents, colorants, tackifiers and binders.

Suitable solvents and liquid carriers are water and organic solvents, such as mineral oil fractions of medium to high boiling point, e.g. kerosene, diesel oil; oils of vegetable or animal origin; aliphatic, cyclic and aromatic hydrocarbons, e. g. toluene, paraffin, tetrahydronaphthalene, alkylated naphthalenes; alcohols, e.g. ethanol, propanol, butanol, benzylalcohol, cyclohexanol; glycols; DMSO; ketones, e.g. cyclohexanone; esters, e.g. lactates, carbonates, fatty acid esters, gamma-butyrolactone; fatty acids; phosphonates; amines; amides, e.g. N-methylpyrrolidone, fatty acid dimethylamides; and mixtures thereof.

Suitable solid carriers or fillers are mineral earths, e.g. silicates, silica gels, talc, kaolins, limestone, lime, chalk, clays, dolomite, diatomaceous earth, bentonite, calcium sulfate, magnesium sulfate, magnesium oxide; polysaccharide powders, e.g. cellulose, starch; fertilizers, e.g. ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas; products of vegetable origin, e.g. cereal meal, tree bark meal, wood meal, nutshell meal, and mixtures thereof.

Suitable surfactants are surface-active compounds, such as anionic, cationic, nonionic and amphoteric surfactants, block polymers, poly electrolytes, and mixtures thereof. Such surfactants can be used as emusifier, dispersant, solubilizer, wetter, penetration enhancer, protective colloid, or adjuvant. Examples of surfactants are listed in McCutcheon's, Vol.l : Emulsifiers and Detergents, McCutcheon's Directories, Glen Rock, USA, 2008 (International Ed. or North American Ed.).

Suitable anionic surfactants are alkali, alkaline earth or ammonium salts of sulfonates, sulfates, phosphates, carboxylates, and mixtures thereof. Examples of sulfonates are alkylarylsulfonates, diphenylsulfonates, alpha-olefin sulfonates, lignine sulfonates, sulfonates of fatty acids and oils, sulfonates of ethoxylated alkylphenols, sulfonates of alkoxylated arylphenols, sulfonates of condensed naphthalenes, sulfonates of dodecyland tridecylbenzenes, sulfonates of naphthalenes and alkylnaphthalenes, sulfosuccinates or sulfosuccinamates. Examples of sulfates are sulfates of fatty acids and oils, of ethoxylated alkylphenols, of alcohols, of ethoxylated alcohols, or of fatty acid esters. Examples of phosphates are phosphate esters. Examples of carboxylates are alkyl carboxylates, and carboxylated alcohol or alkylphenol ethoxylates.

Suitable nonionic surfactants are alkoxylates, N-subsituted fatty acid amides, amine oxides, esters, sugar-based surfactants, polymeric surfactants, and mixtures thereof. Examples of alkoxylates are compounds such as alcohols, alkylphenols, amines, amides, arylphenols, fatty acids or fatty acid esters which have been alkoxylated with 1 to 50 equivalents. Ethylene oxide and/or propylene oxide may be employed for the alkoxylation, preferably ethylene oxide. Examples of N-subsititued fatty acid amides are fatty acid glucamides or fatty acid alkanolamides. Examples of esters are fatty acid esters, glycerol esters or monoglycerides. Examples of sugarbased surfactants are sorbitans, ethoxylated sorbitans, sucrose and glucose esters or alkylpolyglucosides. Examples of polymeric surfactants are homeor copolymers of vinylpyrrolidone, vinylalcohols, or vinylacetate.

Suitable cationic surfactants are quaternary surfactants, for example quaternary ammonium compounds with one or two hydrophobic groups, or salts of long-chain primary amines. Suitable amphoteric surfactants are alkylbetains and imidazolines. Suitable block polymers are block polymers of the A-B or A-B-A type comprising blocks of polyethylene oxide and polypropylene oxide, or of the A-B-C type comprising alkanol, polyethylene oxide and polypropylene oxide. Suitable polyelectrolytes are polyacids or polybases. Examples of polyacids are alkali salts of polyacrylic acid or polyacid comb polymers. Examples of polybases are polyvinylamines or polyethyleneamines.

Suitable adjuvants are compounds, which have a neglectable or even no pesticidal activity themselves, and which improve the biological performance of the compound I on the target. Examples are surfactants, mineral or vegetable oils, and other auxilaries. Further examples are listed by Knowles, Adjuvants and additives, Agrow Reports DS256, T and F Informa UK, 2006, chapter 5.

Suitable thickeners are polysaccharides (e.g. xanthan gum, carboxymethylcellulose), anorganic clays (organically modified or unmodified), polycarboxylates, and silicates. Suitable bactericides are bronopol and isothiazolinone derivatives such as alkylisothiazolinones and benzisothiazolinones. Suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glycerin. Suitable anti-foaming agents are silicones, long chain alcohols, and salts of fatty acids. Suitable colorants (e.g. in red, blue, or green) are pigments of low water solubility and watersoluble dyes. Examples are inorganic colorants (e.g. iron oxide, titan oxide, iron hexacyanoferrate) and organic colorants (e.g. alizarin-, azoand phthalocyanine colorants). Suitable tackifiers or binders are polyvinylpyrrolidone, polyvinylacetates, polyvinyl alcohols, polyacrylates, biological or synthetic waxes, and cellulose ethers.

Examples for composition types and their preparation are:

i) Water-soluble concentrates (SL, LS)

10-60 wt% of a compound I or an N-oxide or salt thereof and 5-15 wt% wetting agent (e.g. alcohol alkoxylates) are dissolved in water and/or in a water-soluble solvent (e.g. alcohols) up to 100 wt%. The active substance dissolves upon dilution with water.

ii) Dispersible concentrates (DC)

5-25 wt% of a compound I or an N-oxide or salt thereof and 1-10 wt% dispersant (e. g. polyvinylpyrrolidone) are dissolved in up to 100 wt% organic solvent (e.g. cyclohexanone). Dilution with water gives a dispersion.

iii) Emulsifiable concentrates (EC)

15-70 wt% of a compound I or an N-oxide or salt thereof and 5-10 wt% emulsifiers (e.g. calcium dodecylbenzenesulfonate and castor oil ethoxylate) are dissolved in up to 100 wt% waterinsoluble organic solvent (e.g. aromatic hydrocarbon). Dilution with water gives an emulsion iv) Emulsions (EW, EO, ES) 5-40 wt% of a compound I or an N-oxide or salt thereof and 1 -10 wt% emulsifiers (e.g. calcium dodecylbenzenesulfonate and castor oil ethoxylate) are dissolved in 20-40 wt% water-insoluble organic solvent (e.g. aromatic hydrocarbon). This mixture is introduced into up to 100 wt% water by means of an emulsifying machine and made into a homogeneous emulsion. Dilution with water gives an emulsion v) Suspensions (SC, OD, FS)

In an agitated ball mill, 20-60 wt% of a compound I or an N-oxide or salt thereof are comminuted with addition of 2-10 wt% dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate), 0,1 -2 wt% thickener (e.g. xanthan gum) and up to 100 wt% water to give a fine active substance suspension. Dilution with water gives a stable suspension of the active substance. For FS type composition up to 40 wt% binder (e.g. polyvinylalcohol) is added.

vi) Water-dispersible granules and water-soluble granules (WG, SG)

50-80 wt% of a compound I or an N-oxide or salt thereof are ground finely with addition of up to 100 wt% dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate) and prepared as water-dispersible or water-soluble granules by means of technical appliances (e. g. extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active substance.

vii) Water-dispersible powders and water-soluble powders (WP, SP, WS)

50-80 wt% of a compound I or an N-oxide or salt thereof are ground in a rotor-stator mill with addition of 1 -5 wt% dispersants (e.g. sodium lignosulfonate), 1-3 wt% wetting agents (e.g. alcohol ethoxylate) and up to 100 wt% solid carrier, e.g. silica gel. Dilution with water gives a stable dispersion or solution of the active substance.

viii) Gel (GW, GF)

In an agitated ball mill, 5-25 wt% of a compound I or an N-oxide or salt thereof are comminuted with addition of 3-10 wt% dispersants (e.g. sodium lignosulfonate), 1-5 wt% thickener (e.g. carboxymethylcellulose) and up to 100 wt% water to give a fine suspension of the active substance. Dilution with water gives a stable suspension of the active substance,

iv) Microemulsion (ME) 5-20 wt% of a compound I or an N-oxide or salt thereof are added to 5-30 wt% organic solvent blend (e.g. fatty acid dimethylamide and cyclohexanone), 10-25 wt% surfactant blend (e.g. alkohol ethoxylate and arylphenol ethoxylate), and water up to 100 %. This mixture is stirred for 1 h to produce spontaneously a thermodynamically stable microemulsion

iv) Microcapsules (CS)

An oil phase comprising 5-50 wt% of a compound I or an N-oxide or salt thereof, 0-40 wt% water insoluble organic solvent (e.g. aromatic hydrocarbon), 2-15 wt% acrylic monomers (e.g. methylmethacrylate, methacrylic acid and a dior triacrylate) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). Radical polymerization initiated by a radical initiator results in the formation of poly(methyl acrylate) microcapsules. Alternatively, an oil phase comprising 5-50 wt% of a compound I according to the present invention, 0-40 wt% water insoluble organic solvent (e.g. aromatic hydrocarbon), and an isocyanate monomer (e.g. diphenylmethene-4,4'-diisocyanatae) are dispersed into

an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). The addition of a polyamine (e.g. hexamethylenediamine) results in the formation of polyurea microcapsules. The monomers amount to 1 -10 wt%. The wt% relate to the total CS composition,

ix) Dustable powders (DP, DS) 1-10 wt% of a compound I or an N-oxide or salt thereof are ground finely and mixed intimately with up to 100 wt% solid carrier, e.g. finely divided kaolin.

x) Granules (GR, FG) 0.5-30 wt% of a compound I or an N-oxide or salt thereof is ground finely and associated with up to 100 wt% solid carrier (e.g. silicate). Granulation is achieved by extrusion, spray drying or the fluidized bed.

xi) Ultra-low volume liquids (UL) 1-50 wt% of a compound I or an N-oxide or salt thereof are dissolved in up to 100 wt% organic solvent, e.g. aromatic hydrocarbon.

The compositions types i) to xi) may optionally comprise further auxiliaries, such as 0.1-1 wt% bactericides, 5-15 wt% anti-freezing agents, 0.1-1 wt% anti-foaming agents, and 0.1 -1 wt% colorants.

In one another embodiment of present invention provides a agrochemical compositions compound of Formula I, which comprise active substance between 0.01 and 95% by weight, preferably between 0.1 and 90%, and more preferably between 1 and 70 %, in particular between 10 and 60 by weight of active substance. The active substances are employed in a purity of from 90% to 100%, preferably from 95% to 100% (according to NMR spectrum).

Water-soluble concentrates (LS), Suspoemulsions (SE), flowable concentrates (FS), powders for dry treatment (DS), water-dispersible powders for slurry treatment (WS), water-soluble powders (SS), emulsions (ES), emulsifiable concentrates (EC) and gels (GF) are usually employed for the purposes of treatment of plant propagation materials, particularly seeds. The compositions in question give, after two-to-tenfold dilution, active substance concentrations of from 0.01 to 60% by weight, preferably from 0.1 to 40% by weight, in the ready-to-use preparations. Application can be carried out before or during sowing.

Methods for applying or treating compound I and compositions thereof, respectively, on to plant propagation material, especially seeds include dressing, coating, pelleting, dusting, soaking and in-furrow application methods of the propagation material. Preferably, compound I or the compositions thereof, respectively, are applied on to the plant propagation material by a method such that germination is not induced, e. g. by seed dressing, pelleting, coating and dusting.

When employed in plant protection, the amounts of active substances applied are, depending on the kind of effect desired, from 0.001 to 2 kg per ha, preferably from 0.005 to 2 kg per ha, more preferably from 0.05 to 0.9 kg per ha, in particular from 0.1 to 0.75 kg per ha.

In treatment of plant propagation materials such as seeds, e. g. by dusting, coating or drenching seed, amounts of active substance of from 0.1 to 1000 g, preferably from 1 to 1000 g, more preferably from 1 to 100 g and most preferably from 5 to 100 g, per 100 kilogram of plant propagation material (preferably seed) are generally required.

When used in the protection of materials or stored products, the amount of active substance applied depends on the kind of application area and on the desired effect. Amounts customarily applied in the protection of materials are 0.001 g to 2 kg, preferably 0.005 g to 1 kg, of active substance per cubic meter of treated material.

Various types of oils, wetters, adjuvants, fertilizer, or micronutrients, and other pesticides (e.g. herbicides, insecticides, fungicides, growth regulators, safeners) may be added to the active substances or the compositions comprising them as premix or, if appropriate not until immediately prior to use (tank mix). These agents can be admixed with the compositions according to the present invention in a weight ratio of 1:100 to 100:1, preferably 1:10 to 10:1.

The user can apply the composition according to the present invention usually from a predosage device, a knapsack sprayer, a spray tank, a spray plane, or an irrigation system. Usually, the agrochemical composition is made up with water, buffer, and/or further auxiliaries to the desired application concentration and the ready-to-use spray liquor or the agrochemical composition according to the present invention is thus obtained. Usually, 20 to 2000 liters, preferably 50 to 400 liters, of the ready-to-use spray liquor are applied per hectare of agricultural useful area.

According to one embodiment, individual components of the composition according to the present invention such as parts of a kit or parts of a binary or ternary mixture may be mixed by the user himself in a spray tank and further auxiliaries may be added, if appropriate.

The compounds and compositions of the present invention are thus useful agronomically for protecting field crops from phytophagous invertebrate pests, and also nonagronomically for protecting other horticultural crops and plants from phytophagous invertebrate pests. This utility includes protecting crops and other plants (i.e. both agronomic and nonagronomic) that contain genetic material introduced by genetic engineering (i.e. transgenic) or modified by mutagenesis to provide advantageous traits.

Compounds of the present invention are characterized by favorable metabolic and/or soil residual patterns and exhibit activity controlling a spectrum of agronomic and non-agronomic invertebrate pests. The compounds of the present invention are preventively and/or curatively valuable active ingredients in the field of pest control, even at low rates of application, which can be used against pesticide resistant pests such as insects and fungi, and/or have a very favorable biocidal spectrum and are well tolerated by warm blooded species, fish and plants.

In the context of the present invention“invertebrate pest control” means inhibition of invertebrate pest development (including mortality) that causes significant reduction in feeding or other injury or damage caused by the pest; related expressions are defined analogously.) As referred to in the present invention, the term“invertebrate pest” includes arthropods, gastropods andnematodes of economic importance as pests. The term“arthropod” includes insects, mites, spiders, scorpions, centipedes, millipedes, pill bugs and symphylans.

The term“gastropod” includes snails, slugs and other Stylommatophora. The term“nematode” includes all of the helminths, such as: roundworms, heartworms, and phytophagous nematodes (Nematoda), flukes (Tematoda), Acanthocephala, and tapeworms (Cestoda). Those skilled in the art will recognize that not all compounds are equally effective against all pests.

Compounds of the present invention display activity against economically important agronomic, forest, greenhouse, nursery, ornamentals, food and fiber, public and animal health, domestic and commercial structure, household, and stored product pests. These include larvae of the order Lepidoptera, such as armyworms, cutworms, loopers, and heliothines in the family Noctuidae (e.g., fall armyworm ( Spodoptera fugiperda J. E. Smith), beet armyworm ( Spodoptera exigua Hubner), black cutworm (. Agrotis ipsilon Hufnagel), cabbage looper ( Trichoplusia ni Hubner), tobacco budworm ( Heliothis virescens Fabricius)); borers, casebearers, webworms, coneworms, cabbageworms and skeletonizers from the family Pyralidae (e.g., European corn borer ( Ostrinia nubilalis Hubner), navel orangeworm ( Amyelois transitella Walker), corn root webworm ( Crambus caliginosellus Clemens), sod webworm ( Herpetogramma licarsisalis Walker)); leafrohers, budworms, seed worms, and fruit worms in the family Tortricidae (e.g., codling moth ( Cydia pomonella Linnaeus), grape berry moth ( Endopiza viteana Clemens), oriental fruit moth ( Grapholita molesta Busck)); and many other economically important lepidoptera (e.g., diamondback moth ( Plutella xylostella Linnaeus), pink bollworm ( Pectinophora

gossypiella Saunders), gypsy moth ( Lymantria dispar Linnaeus)); nymphs and adults of the order Blattodea mcluding cockroaches from the families Blattellidae and Blattidae (e.g., oriental cockroach ( Blatta orientalis Linnaeus), Asian cockroach ( Blatella asahinai Mizukubo), German cockroach ( Blattella gemnanica Linnaeus), brownbanded cockroach ( Supella longipalpa Fabricius), American cockroach ( Periplaneta americana Linnaeus), brown cockroach ( Periplaneta brunnea Burmeister), Madeira cockroach ( Leucophaea maderae Fabricius)); foliar feeding larvae and adults of the order Coleoptera including weevils from the families Anthribidae, Bruchidae, and Curculionidae (e.g., boll weevil (. Anthonomus grandis Boheman), rice water weevil ( Lissorhoptrus oryzophilus Kuschel), granary weevil ( Sitophilus granarius Linnaeus), rice weevil ( Sitophilus oryzae Linnaeus)); flea beetles, cucumber beetles, rootworms, leaf beetles, potato beetles, and leafminers in the family Chrysomelidae (e.g., Colorado potato beetle ( Leptinotarsa decemlineata Say), western corn rootworm ( Diabrotica virgifera virgifera LeConte)); chafers and other beetles from the family Scaribaeidae (e.g., Japanese beetle ( Popillia japonica Newman) and European chafer ( Rhizotrogus majalis Razoumowsky)); carpet beetles from the family Dermestidae; wireworms from the family Elateridae; bark beetles from the family Scolytidae and flour beetles from the family Tenebrionidae. In addition it includes: adults and larvae of the order Dermaptera including earwigs from the family Forficulidae (e.g., European earwig ( Forficula auricularia Linnaeus), black earwig ( Chelisoches mono Fabricius)); adults and nymphs of the orders Hemiptera and Homoptera such as, plant bugs from the family Miridae, cicadas from the family Cicadidae, leafhoppers (e.g. Empoasca spp.) from the family Cicadellidae, planthoppers from the families Fulgoroidae and Delphacidae, treehoppers from the family Membracidae, psyllids from the family Psyllidae, whitefiies from the family Aleyrodidae, aphids from the family Aphididae, phylloxera from the family Phylloxeridae, mealybugs from the family Pseudococcidae, scales from the families Coccidae, Diaspididae and Margarodidae, lace bugs from the family Tingidae, stink bugs from the family Pentatomidae, cinch bugs (e.g., Blissus spp.) and other seed bugs from the family Lygaeidae, spittlebugs from the family Cercopidae squash bugs from the family Coreidae, and red bugs and cotton stainers from the family Pyrrhocoridae. Also included are adults and larvae of the order Acari (mites) such as spider mites and red mites in the family Tetranychidae (e.g., European red mite ( Panonychus ulmi Koch), two spotted spider mite ( Tetranychus urticae Koch), McDaniel mite ( Tetranychus mcdanieli McGregor)), flat mites in the family Tenuipalpidae (e.g., citrus flat mite ( Brevipalpus lewisi McGregor)), rust and bud mites in the family Eriophyidae and other foliar feeding mites and mites important in human and animal health, i.e. dust mites in the family Epidermoptidae, follicle mites in the family Demodicidae, grain mites in the family Glycyphagidae, ticks in the order Ixodidae (e.g., deer tick ( Ixodes scapularis Say), Australian paralysis tick ( Ixodes holocyclus Neumann), American dog tick ( Dermacentor variabilis Say), lone star tick ( Amblyomma americanum Linnaeus) and scab and itch mites in the families Psoroptidae,

Pyemotidae, and Sarcoptidae; adults and immatures of the order Orthoptera including grasshoppers, locusts and crickets (e.g., migratory grasshoppers (e.g., Melanoplus sanguinipes Fabricius, M. differentialis Thomas), American grasshoppers (e.g., Schistocerca americana Drury), desert locust (Schistocerca gregaria Forskal), migratory locust (Locusta migratoria Linnaeus), house cricket ( Acheta domesticus Linnaeus), mole crickets ( Gryllotalpa spp .)); adults and immatures of the order Diptera including leafminers, midges, fruit flies (Tephritidae), frit flies (e.g., Oscinella frit Linnaeus), soil maggots, house flies (e.g., Musca domestica Linnaeus), lesser house flies (e.g., Fannia canicularis Linnaeus, F.femoralis Stein), stable flies (e.g., Stomoxys calcitrans Linnaeus), face flies, horn flies, blow flies (e.g., Chiysomya spp., Phonnia spp.), and other muscoid fly pests, horse flies (e.g., Tabanus spp.), botflies (e.g., Gastrophilus spp., Oestrus spp.), cattle grubs (e.g., Hypoderma spp.), deer flies (e.g., Chrysops spp.), keds (e.g., Melophagus ovinus Linnaeus) and other Brachycera, mosquitoes (e.g., Aedes spp., Anopheles spp., Culex spp.), black flies (e.g., Prosimulium spp., Simulium spp.), biting midges, sand flies, sciarids, and other Nematocera; adults and immatures of the order Thysanoptera including onion thrips ( Thrips tabaci Lindeman) and other foliar feeding thrips; insect pests of the order Hymenoptera including ants (e.g., red carpenter ant ( Camponotus ferrugineus Fabricius), black carpenter ant ( Camponotus pennsylvanicus De Geer), Pharaoh ant ( Monomorium pharaonis Linnaeus), little fire ant ( Wasmannia auropunctata Roger), fire ant ( Solenopsis geminata Fabricius), red imported fire ant ( Solenopsis invicta Buren), Argentine ant ( Iridomyrmex humilis Mayr), crazy ant ( Paratrechina longicornis Latreille), pavement ant ( Tetramorium caespitum Linnaeus), cornfield ant ( Lasius alienus Fdrster), odorous house ant ( Tapinoma sessile Say)), bees (including carpenter bees), hornets, yellow jackets and wasps; insect pests of the order Isoptera including the eastern subterranean termite (Reticulitermes flavipes Kollar), western subterranean termite ( Reticulitermes hesperus Banks), Formosan subterranean termite ( Coptotermes formosanus Shiraki), West Indian drywood termite ( Incisitermes immigrans Snyder) and other termites of economic importance; insect pests of the order Thysanura such as silverfish ( Lepisma saccharina Linnaeus) and firebrat ( Thermobia domestica Packard); insect pests of the order Mallophaga and including the head louse ( Pediculus humanus capitis De Geer), body louse ( Pediculus humanus humanus Linnaeus), chicken body louse ( Menacanthus stramineus Nitszch), dog biting louse ( Trichodectes cams De Geer), fluff louse ( Goniocotes gallinae De Geer), sheep body louse ( Bovicola ovis Schrank), short-nosed cattle louse ( Haematopinus eurystemus Nitzsch), long-nosed cattle louse ( Linognathus vituli Linnaeus) and other sucking and chewing parasitic lice that attack man and animals; insect pests of the order Siphonoptera including the oriental rat flea ( Xenopsylla cheopis Rothschild), cat flea ( Ctenocephalides felis Bouche), dog flea ( Ctenocephatides canis Curtis), hen flea ( Ceratophyllus gallinae Schrank), sticktight flea ( Echidnophaga gallinacea Westwood), human flea ( Pulex irritans Linnaeus) and other fleas afflicting mammals and birds. Additional arthropod pests

covered include: spiders in the order Araneae such as the brown recluse spider ( Loxosceles reclusa Gertsch and Mulaik) and the black widow spider ( Latrodectus mactans Fabricius), and centipedes in the order Scutigeromorpha such as the house centipede ( Scutigera coleoptrata Linnaeus). Activity also includes members of the Classes Nematoda, Cestoda, Trematoda, and Acanthocephala including economically important members of the orders Strongylida, Ascaridida, Oxyurida, Rhabditida, Spirurida, and Enoplida such as but not limited to economically important agricultural pests (i.e. root knot nematodes in the genus Meloidogyne, lesion nematodes in the genus Pratylenchus, stubby root nematodes in the genus Trichodorus, etc.) and animal and human health pests (i.e. all economically important flukes, tapeworms, and roundworms, such as Strongylus vulgaris in horses, Toxocara cants in dogs, Haemonchus contortus in sheep, Dirofllaria immitis Leidy in dogs, Anoplocephala peifoliata in horses, Fasciola hepatica Linnaeus in ruminants, etc.).

Compounds of the present invention show particularly high activity against pests in the order Lepidoptera (e.g., Alabama argillacea Hubner (cotton leaf worm), Archips argyrospila Walker (fruit tree leaf roller), A. rosana Linnaeus (European leaf roller) and other Archips species, Chilo suppressalis Walker (rice stem borer), Cnaphalocrosis medinalis Guenee (rice leaf roller), Crambus caliginosellus Clemens (corn root webworm), Crambus teterrellus Zincken (bluegrass webworm), Cydia pomonella Linnaeus (codling moth), Earias insulana Boisduval (spiny bollworm), Earias vittella Labricius (spotted bollworm), Helicoveipa armigera Hhbner (American bollworm), Helicoverpa zea Boddie (corn earworm), Heliothis virescens Labricius (tobacco budworm), Herpetogramma licarsisalis Walker (sod webworm), Lobesia botrana Denis and Schiffe tnoller (grape berry moth), Pectinophora gossypiella Saunders (pink bollworm), Phyllocnistis citrella Stainton (citrus leafminer), Pieris brassicae Linnaeus (large white butterfly), Pieris rapae Linnaeus (small white butterfly), Plutella xylostella Linnaeus (diamondback moth), Spodoptera exigua Hubner (beet armyworm), Spodoptera litura Labricius (tobacco cutworm, cluster caterpillar), Spodoptera frugiperda J. E. Smith (fall armyworm), Trichoplusia ni Hhbner (cabbage looper) and Tula absoluta Meyrick (tomato leafminer)). Compounds of the present invention also have commercially significant activity on members from the order Homoptera including: Acyrthisiplionpisum Harris (pea aphid), Aphis craccivora Koch (cowpea aphid), Aphis fabae Scopoli (black bean aphid), Aphis gossypii Glover (cotton aphid, melon aphid), Aphis pomi De Geer (apple aphid), Aphis spiraecola Patch (spirea aphid), Aulacorthum solani Kaltenbach (foxglove aphid), Chaetosiphon fragaefolii Cockerell (strawberry aphid), Diuraphis noxia Kurdjumov/Mordvilko (Russian wheat aphid), Dysaphis plantaginea Paaserini (rosy apple aphid), Eriosoma lanigerum Hausmann (woolly apple aphid), Hyalopterus pruni Geoffroy (mealy plum aphid), Lipaphis erysimi Kaltenbach (tarnip aphid), Metopolophium dirrhodum Walker (cereal aphid), Macrosipum euphorbiae Thomas (pqtato aphid),

Myzus persicae Sulzer (peach-potato aphid, green peach aphid), Nasonovia ribisnigri Mosley (lettuce aphid), Pemphigus spp. (root aphids and gall aphids), Rhopalosiphum maidis Fitch (corn leaf aphid), Rhopalosiphum padi Linnaeus (bird cherry-oat aphid), Schizaphis graminum Rondani (greenbug), Sitobion avenae Fabricius (English grain aphid), Therioaphis maculata Buckton (spotted alfalfa aphid), Toxoptera aurantii, Boyer de Fonscolombe (black citrus aphid), and Toxoptera citiicida Kirkaldy (brown citrus aphid); Adelges spp. (adelgids); Phylloxera devastatrix Pergande (pecan phylloxera); Bemisia tabaci Gennadius (tobacco whitefly, sweetpotato whitefly), Bemisia argentifolii Bellows and Perring (silverleaf whitefly), Dialeurodes citri Ashmead (citrus whitefly) and Trialeurodes vaporariorum Westwood (greenhouse whitefly); Empoasca fabae Harris, (potato leafhopper), Laodelphax striatellus Fallen (smaller brown planthopper), Macrolestes quadrilineatus Forbes (aster leafhopper), Nephotettix cinticeps Uhler (green leafhopper), Nephotettix nigropictus Stal (rice leafhopper), Nilaparvata lugens Stal (brown planthopper), Peregrinus maidis Ashmead (corn planthopper), Sogatella furcifera Horvath (white-backed planthopper), Sogatodes orizicola Muir (rice delphacid), Typhlocyba pomaria McAfee white apple leafhopper, Erythroneoura spp. (grape leafhoppers); Magicidada septendecim Linnaeus (periodical cicada); Icerya purchasi Maskell (cottony cushion scale), Quadraspidiotus perniciosus Comstock (San Jose scale); Planococcus citri Risso (citrus mealybug); Pseudococcus spp. (other mealybug complex); Cacopsylla pyricola Foerster (pear psylla), Trioza diospyri Ashmead (persimmon psylla).

These compounds also have activity on members from the order Hemiptera including: Acrostemum hilare Say (green stink bug), Anasa tristis De Geer (squash bug), Blissus leucopterus leucopterus Say (chinch bug), Corythuca gossypii Fabricius (cotton lace bug), Cyrtopeltis modesta Distant (tomato bug), Dysdercus suturellus Herrich-S chaffer (cotton stainer), Euchistus servus Say (brown stink bug), Euchistus variolrius Palisot deBeauvois (one-spotted stink bug), Graptosthetus spp. (complex of seed bugs), Leptoglossus corculus Say (leaf- footed pine seed bug), Lygus lineolaris Palisot de Beauvois (tarnished plant bug), Nezara viridula Linnaeus (southern green stink bug), Oebalus pugnax Labricius (rice stink bug), Oncopeltus fasciatus DaEas (large milkweed bug), Pseudatomoscelis seriatus Reuter (cotton fleahopper).

Other insect orders controlled by compounds of the present invention include Thysanoptera (e.g., Frankliniella occidentalis Pergande (western flower thrip), Scirthot^ps citri Moulton (citrus thrip), Sericothrips variabilis Beach (soybean thrip), and Thrips tabaci Lindeman (onion thrip); and the order Coleoptera (e.g., Leptinotarsa decemlineata Say (Colorado potato beetle), Epilachna varivestis Mulsant (Mexican bean beetle) and wireworms of the genera Agriotes, Athous or Limonius).

Particularly, the compounds of Formula I, their N-oxides, their isomers, their polymorphs and their salts are especially suitable for efficiently combating the following pests: Insects from the order of the lepidopterans (Lepidoptera), for example Agrotis ypsilon, Agrotis segetum, Alabama argillacea, Anticarsia gemmatalis, Argyresthia conjugella, Autographa gamma, Bupalus piniarius, Cacoecia murinana, Capua reticulana, Cheimatobia brumata, Chilo infuscatellus, Choristoneura fumiferana, Choristoneura occidentalis, Cirphis unipuncta, Cydia pomonella, Dendrolimus pini, Diaphania nitidalis, Diatraea grandiosella, Earias insulana, Earias vittella, Elasmopalpus lignosellus, Eupoecilia ambiguella, Evetria bouliana, Feltia subterranea, Galleria mellonella, Grapholita funebrana, Grapholita molesta, Helicoverpa armigera, Helicoverpa virescens, Helicoverpa zea, Hellula undalis, Hibernia defoliaria, Hyphantria cunea, Hyponomeuta malinellus, Keiferia lycopersicella, Lambdina fiscellaria, Laphygma exigua, Leucoptera coffeella, Leucoptera scitella, Lithocolletis blancardella, Lobesia botrana, Loxostege sticticalis, Leucinodes orbonalis, Lymantria dispar, Lymantria monacha, Lyonetia clerkella, Malacosoma neustria, Mamestra brassicae, Orgyia pseudotsugata, Ostrinia nubilalis, Panolis flammea, Pectinophora gossypiella, Peridroma saucia, Phalera bucephala, Phthorimaea operculella, Phyllocnistis citrella, Pieris brassicae, Plathypena scabra, Plutella xylostella, Pseudoplusia includens, Rhyacionia frustrana, Scirpophaga incertulas, Scrobipalpula absoluta, Sitotroga cerealella, Sparganothis pilleriana, Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Spodoptera exigua, Thaumatopoea pityocampa, Tortrix viridana, Trichoplusia ni and Zeiraphera canadensis, and

Beetles (Coleoptera), for example Agrilus sinuatus, Agriotes lineatus, Agriotes obscurus, Amphimallus solstitialis, Anisandrus dispar, Anthonomus grandis, Anthonomus pomorum, Aphthona euphoridae, Athous haemorrhoidalis, Atomaria linearis, Blastophagus piniperda, Blitophaga undata, Bruchus rufimanus, Bruchus pisorum, Bruchus lends, Byctiscus betulae, Cassida nebulosa, Cerotoma trifurcata, Cetonia aurata, Ceuthorrhynchus assimilis, Ceuthorrhynchus napi, Chaetocnema tibialis, Conoderus vespertinus, Crioceris asparagi, Ctenicera ssp., Diabrotica longicornis, Diabrotica semipunctata, Diabrotica undecimpunctata Diabrotica speciosa, Diabrotica virgifera, Epilachna varivestis, Epitrix hirtipennis, Eutinobothrus brasiliensis, Hylobius abietis, Hypera brunneipennis, Hypera postica, Ips typographus, Lema bilineata, Lema melanopus, Leptinotarsa decemlineata, Limonius californicus, Lissorhoptrus oryzophilus, Melanotus communis, Meligethes aeneus, Melolontha hippocastani, Melolontha melolontha, Oulema oryzae, Otiorrhynchus sulcatus, Otiorrhynchus ovatus, Phaedon cochleariae, Phyllobius pyri, Phyllotreta chrysocephala, Phyllophaga sp., Phyllopertha hordeola, Phyllotreta nemorum, Phyllotreta striolata, Popillia japonica, Sitona lineatus and Sitophilus granaria; flies, mosquitoes (Diptera), e.g. Aedes aegypti, Aedes albopictus, Aedes vexans, Anastrepha ludens, Anopheles maculipennis, Anopheles crucians, Anopheles albimanus, Anopheles gambiae, Anopheles

freeborni, Anopheles leucosphyrus, Anopheles minimus, Anopheles quadrimaculatus, Calliphora vicina, Ceratitis capitata, Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria, Chrysops discalis, Chrysops silacea, Chrysops atlanticus, Cochliomyia hominivorax, Contarinia sorghicola Cordylobia anthropophaga, Culicoides furens, Culex pipiens, Culex nigripalpus, Culex quinquefasciatus, Culex tarsalis, Culiseta inornata, Culiseta melanura, Dacus cucurbitae, Dacus oleae, Dasineura brassicae, Delia antique, Delia coarctata, Delia platura, Delia radicum, Dermatobia hominis, Fannia canicularis, Geomyza Tripunctata, Gasterophilus intestinalis, Glossina morsitans, Glossina palpalis, Glossina fuscipes, Glossina tachinoides, Haematobia irritans, Haplodiplosis equestris, Hippelates spp., Hylemyia platura, Hypoderma lineata, Leptoconops torrens, Liriomyza sativae, Liriomyza trifolii, Lucilia caprina, Lucilia cuprina, Lucilia sericata, Lycoria pectoralis, Mansonia titillanus, Mayetiola destructor, Musca autumnalis, Musca domestica, Muscina stabulans, Oestrus ovis, Opomyza florum, Oscinella frit, Pegomya hysocyami, Phorbia antiqua, Phorbia brassicae, Phorbia coarctata, Phlebotomus argentipes, Psorophora columbiae, Psila rosae, Psorophora discolor, Prosimulium mixtum, Rhagoletis cerasi, Rhagoletis pomonella, Sarcophaga haemorrhoidalis, Sarcophaga spp., Simulium vittatum, Stomoxys calcitrans, Tabanus bovinus, Tabanus atratus, Tabanus lineola, and Tabanus similis, Tipula oleracea, and Tipula paludosa; termites (Isoptera), e.g. Calotermes flavicollis, Leucotermes flavipes, Heterotermes aureus, Reticulitermes flavipes, Reticulitermes virginicus, Reticulitermes lucifugus, Reticulitermes santonensis, Reticulitermes grassei, Termes natalensis, and Coptotermes formosanus; cockroaches (Blattaria Blattodea), e.g. Blattella germanica, Blattella asahinae, Periplaneta americana, Periplaneta japonica, Periplaneta brunnea, Periplaneta fuligginosa, Periplaneta australasiae, and Blatta orientalis; ants, bees, wasps, sawflies (Hymenoptera), e.g. Athalia rosae, Atta cephalotes, Atta capiguara, Atta cephalotes, Atta laevigata, Atta robusta, Atta sexdens, Atta texana, Crematogaster spp., Hoplocampa minuta, Hoplocampa testudinea, Lasius niger, Monomorium pharaonis, Solenopsis geminata, Solenopsis invicta, Solenopsis richteri, Solenopsis xyloni, Pogonomyrmex barbatus, Pogonomyrmex californicus, Pheidole megacephala, Dasymutilla occidentalis, Bombus spp., Vespula squamosa, Paravespula vulgaris, Paravespula pennsylvanica, Paravespula germanica, Dolichovespula maculata, Vespa crabro, Polistes rubiginosa, Camponotus floridanus, and Linepithema humile; crickets, grasshoppers, locusts (Orthoptera), e.g. Acheta domestica, Gryllotalpa gryllotalpa, Locusta migratoria, Melanoplus bivittatus, Melanoplus femurrubrum, Melanoplus mexicanus, Melanoplus sanguinipes, Melanoplus spretus, Nomadacris septemfasciata, Schistocerca americana, Schistocerca gregaria, Dociostaurus maroccanus, Tachycines asynamorus, Oedaleus senegalensis, Zonozerus variegatus, Hieroglyphus daganensis, Kraussaria angulifera, Calliptamus italicus, Chortoicetes terminifera, and Locustana pardalina; Araneida, e.g. Latrodectus mactans, and Loxosceles reclusa; fleas (Siphonaptera), e.g. Ctenocephalides fells, Ctenocephalides canis, Xenopsylla cheopis, Pulex irritans, Tunga penetrans, and Nosopsyllus

fasciatus, silverfish, firebrat ( Thysanura ), e.g. Lepisma saccharina and Thermobia domestica, centipedes (Chilopoda), e.g. Scutigera oleoptrata, millipedes (Diplopoda), e.g. Narceus spp., Earwigs (Dermaptera), e.g. forficula auricularia, lice (Phthiraptera), e.g. Pediculus humanus capitis, Pediculus humanus corporis, Pthirus pubis, Haematopinus eurysternus, Haematopinus suis, Linognathus vituli, Bovicola bovis, Menopon allinae, Menacanthus stramineus and Solenopotes capillatus. Collembola (springtails), e.g. Onychiurus ssp.

They are also suitable for controlling Nematodes: plant parasitic nematodes such as root knot nematodes, Meloidogyne hapla, Meloidogyne incognita, Meloidogyne javanica, and other Meloidogyne species; cyst forming nematodes, Globodera rostochiensis and other Globodera species; Heterodera avenae, Heterodera glycines, Heterodera schachtii, Heterodera trifolii, and other Heterodera species; Seed gall nematodes, Anguina species; Stem and foliar nematodes, Aphelenchoides species; Sting nematodes, Belonolaimus longicaudatus and other Belonolaimus species; Pine nematodes, Bursaphelenchus xylophilus and other Bursaphelenchus species; Ring nematodes, Criconema species, Criconemella species, Criconemoides species, Mesocriconema species; Stem and bulb nematodes, Ditylenchus destructor, Ditylenchus dipsaci and other Ditylenchus species; Awl nematodes, Dolichodorus species; Spiral nematodes, Hello cotylenchus multicinctus and other Helicotylenchus species; Sheath and sheathoid nematodes, Hemicycliophora species and Hemicriconemoides species; Hirshmanniella species; Lance nematodes, Hoploaimus species; false rootknot nematodes, Nacobbus species; Needle nematodes, Longidorus elongatus and other Longidorus species; Lesion nematodes, Pratylenchus neglectus, Pratylenchus penetrans, Pratylenchus curvitatus, Pratylenchus goodeyi and other Pratylenchus species; Burrowing nematodes, Radopholus similis and other Radopholus species; Reniform nematodes, Rotylenchus robustus and other Rotylenchus species; Scutellonema species; Stubby root nematodes, Trichodorus primitivus and other Trichodorus species, Paratrichodorus species; Stunt nematodes, Tylenchorhynchus claytoni, Tylenchorhynchus dubius and other Tylenchorhynchus species; Citrus nematodes, Tylenchulus species; Dagger nematodes, Xiphinema species; and other plant parasitic nematode species.

The compounds of Formula I and their salts are also useful for controlling arachnids (Arachnoidea), such as acarians (Acarina), e.g. of the families Argasidae, Ixodidae and Sarcoptidae, such as Amblyomma americanum, Amblyomma variegatum, Argas persicus, Boophilus annulatus, Boophilus decoloratus, Boophilus microplus, Dermacentor silvarum, Hyalomma truncatum, Ixodes ricinus, Ixodes rubicundus, Ornithodorus moubata, Otobius megnini, Dermanyssus gallinae, Psoroptes ovis, Rhipicephalus appendiculatus, Rhipicephalus evertsi, Sarcoptes scabiei, and Eriophyidae spp. such as Aculus

schlechtendali, Phyllocoptrata oleivora and Eriophyes sheldoni; Tarsonemidae spp. such as Phytonemus pallidus and Polyphagotarsonemus latus; Tenuipalpidae spp. such as Brevipalpus phoenicis; Tetranychidae spp. such as Tetranychus cinnabarinus, Tetranychus kanzawai, Tetranychus pacificus, Tetranychus telarius and Tetranychus urticae, Panonychus ulmi, Panonychus citri, and oligonychus pratensis.

In one another embodiment of present invention provides the compound of Formula I is useful for controlling insects selected form sucking or piercing insects such as insects from the genera Thysanoptera, Diptera and Hemiptera, in particular the following species:

Thysanoptera: Frankliniella fusca, Frankliniella occidentalis, Frankliniella tritici, Scirtothrips citri, Thrips oryzae, Thrips palmi and Thrips tabaci, Diptera, e.g. Aedes aegypti, Aedes albopictus, Aedes vexans, Anastrepha ludens, Anopheles maculipennis, Anopheles crucians, Anopheles albimanus, Anopheles gambiae, Anopheles freeborni, Anopheles leucosphyrus, Anopheles minimus, Anopheles quadrimaculatus, Calliphora vicina, Ceratitis capitata, Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria, Chrysops discalis, Chrysops silacea, Chrysops atlanticus, Cochliomyia hominivorax, Contarinia sorghicola Cordylobia anthropophaga, Culicoides furens, Culex pipiens, Culex nigripalpus, Culex quinquefasciatus, Culex tarsalis, Culiseta inornata, Culiseta melanura, Dacus cucurbitae, Dacus oleae, Dasineura brassicae, Delia antique, Delia coarctata, Delia platura, Delia radicum, Dermatobia hominis, Fannia canicularis, Geomyza Tripunctata, Gasterophilus intestinalis, Glossina morsitans, Glossina palpalis, Glossina fuscipes, Glossina tachinoides, Haematobia irritans, Haplodiplosis equestris, Hippelates spp., Hylemyia platura, Hypoderma lineata, Feptoconops torrens, Firiomyza sativae, Firiomyza trifolii, Fucilia caprina, Fucilia cuprina, Fucilia sericata, Fycoria pectoralis, Mansonia titillanus, Mayetiola destructor, Musca autumnalis, Musca domestica, Muscina stabulans, Oestrus ovis, Opomyza florum, Oscinella frit, Pegomya hysocyami, Phorbia antiqua, Phorbia brassicae, Phorbia coarctata, Phlebotomus argentipes, Psorophora columbiae, Psila rosae, Psorophora discolor, Prosimulium mixtum, Rhagoletis cerasi, Rhagoletis pomonella, Sarcophaga haemorrhoidalis, Sarcophaga spp., Simulium vittatum, Stomoxys calcitrans, Tabanus bovinus, Tabanus atratus, Tabanus lineola, and Tabanus similis, Tipula oleracea, and Tipula paludosa; Hemiptera, in particular aphids: Acyrthosiphon onobrychis, Adelges laricis, Aphidula nasturtii, Aphis fab ae, Aphis forbesi, Aphis pomi, Aphis gossypii, Aphis grossulariae, Aphis schneideri, Aphis spiraecola, Aphis sambuci, Acyrthosiphon pisum, Aulacorthum solani, Brachycaudus cardui, Brachycaudus helichrysi, Brachycaudus persicae, Brachycaudus prunicola, Brevicoryne brassicae, Capitophorus horni, Cerosipha gossypii, Chaetosiphon fragaefolii, Cryptomyzus ribis, Dreyfusia nordmannianae, Dreyfusia piceae, Dysaphis radicola,

Dysaulacorthum pseudosolani, Dysaphis plantaginea, Dysaphis pyri, Empoasca fabae, Hyalopterus pruni, Hyperomyzus lactucae, Macrosiphum avenae, Macrosiphum euphorbiae, Macrosiphon rosae, Megoura viciae, Melanaphis pyrarius, Metopolophium dirhodum, Myzodes persicae, Myzus ascalonicus, Myzus cerasi, Myzus varians, Nasonovia ribis-nigri, Nilaparvata lugens, Pemphigus bursarius, Perkinsiella saccharicida, Phorodon humuli, Psylla mail, Psylla piri, Rhopalomyzus ascalonicus, Rhopalosiphum maidis, Rhopalosiphum padi, Rhopalosiphum insertum, Sappaphis mala, Sappaphis mali, Schizaphis graminum, Schizoneura lanuginosa, Sitobion avenae, Trialeurodes vaporariorum, Toxoptera aurantiiand, and Viteus vitifolii.

The present invention further relates to a composition comprising a biologically effective amount of the compound of Formula I and at least one additional biological active compatible compound selected from fungicides, insecticides, nematicides, acaricides, biopesticides, herbicides, plant growth regulators, antibiotics, fertilizers and nutrients. The compounds used in the composition and in combination with the compound of Formula I are also termed as active compatible compounds.

The known and reported fungicides, insecticides, nematicides, acaricides, biopesticides, herbicides, plant growth regulators, antibiotics and nutrients can be combined with at least one compound of the Formula I of the present disclosure. For example, fungicides, insecticides, nematicides, acaricides, biopesticides, herbicides, plant growth regulators, antibiotics, fertilizers and nutrients disclosed and reported in WO2016156129 and or W02017153200 can be combined with at least one compound of the Formula I of the present disclosure.

The fungicides, insecticides, nematicides, acaricides, biopesticides, herbicides, plant growth regulators, antibiotics, fertilizers and nutrients reported in WO2016156129 and or W02017153200 are incorporated herein by way of reference as non-limiting examples to be combined with at least one compound of the Formula I of the present disclosure.

Particularly, the compounds of the present invention can be mixed with at least one additional biological active compatible compound which includes but is not limited to insecticides, fungicides, nematocides, bactericides, acaricides, growth regulators such as rooting stimulants, chemosterilants, semiochemicals, repellents, attractants, pheromones, feeding stimulants, other biologically active compounds or entomopathogenic bacteria, virus or fungi to form a multi-component pesticide giving an even broader spectrum of agricultural utility.

Examples of such biologically active compounds or agents with which compounds of the present invention can be formulated are:

insecticides such as abamectin, acephate, acetamiprid, amidoflumet (S-1955), avermectin, azadirachtin, azinphos-methyl, bifenthrin, binfenazate, buprofezin, carbofuran, chlorfenapyr, chlorfluazuron, chlorpyrifos, chlorpyrif os -methyl, chromafenozide, clothianidin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, cypermethrin, cyromazine, delta ethrin, diafenthiuron, diazinon, diflubenzuron, dimethoate, diofenolan, emamectin, endosulfan, esfenvalerate, ethiprole, fenothicarb, fenoxycarb, fenpropathrin, fenproximate, fenvalerate, fipronil, flonicamid, flucythrinate, tau-fluvabnate, flufenerim (UR-50701), flufenoxuron, fonophos, halofenozide, hexaflumuron, imidacloprid, indoxacarb, isofenphos, lufenuron, malathion, metaldehyde, methamidophos, methidathion, methomyl, methoprene, methoxychlor, monocrotophos, methoxyfenozide, nithiazin, novaluron, noviflumuron (XDE-007), oxamyl, parathion, parathion-methyl, permethrin, phorate, phosalone, phosmet, phosphamidon, pirimicarb, profenofos, pymetrozine, pyridalyl, pyriproxyfen, rotenone, spinosad, spiromesifin (BSN 2060), sulprofos, tebufenozide, teflubenzuron, tefluthrin, terbufos, tetrachlorvinphos, thiacloprid, thiamethoxam, thiodicarb, thiosultap-s odium, tralomethrin, trichlorfon and triflumuron;

fungicides such as acibenzolar, azoxystrobin, benomyl, blasticidin-S, Bordeaux mixture (tribasic copper sulfate), bromuconazole, carpropamid, captafol, captan, carbendazim, chloroneb, chlorothalonil, copper oxychloride, copper salts, cyflufenamid, cymoxanil, cyproconazole, cyprodinil, (S)-3,5-dichloro-N-(3-chloro-l-ethyl-l-methyl-2- oxopropyl)-4-methylbenzamide (RH 7281), diclocymet (S-2900), diclomezine, dicloran, difenoconazole, (S)-3,5-ώhydro-5-me yl-2- (meylt o)-5 -phenyl-3 -(phenylarttino)-4H- imidazol-4-one (RP 407213), dimethomorph, dimoxystrobin, diniconazole, diniconazole-M, dodine, edifenphos, epoxiconazole, famoxadone, fenamidone, fenarimol, fenbuconazole, iprovabcarb (SZX0722), fenpiclonil, fenpropidin, fenpropimorph, fentin acetate, fentin hydroxide, fluazinam, fludioxonil, flumetover (RPA 403397), flumorf/flumorhn (SYP- L190), fluoxastrobin (HEC 5725), fluquinconazole, flusilazole, flutolanil, flutriafol, folpet, fosetyl-aluminum, furalaxyl, furametapyr (S -82658), hexaconazole, ipconazole, iprobenfos, iprodione, isoprothiolane, kasugamycin, kresoxim-methyl, mancozeb, maneb, mefenoxam, mepronil, metalaxyl, metconazole, metom ostrobin/fenominostrobin (SSF- 126), metrafenone (AC 375839), myclobutanil, neo-asozin (ferric methanearsonate), nicobifen (BAS 510), orysastrobin, oxadixyl, penconazole, pencycuron, probenazole, prochloraz, propamocarb, propiconazole, proquinazid (DPX-KQ926), prothioconazole (JAU 6476),

AMENDED CLAIMS

received by the International Bureau on 29 April 2019

1. A compound of formula (I),

wherein;

R1 is NR10RU;

R10 is selected from the group consisting of hydrogen, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalky l-Ci -Cr, alkyl, C 1 -Cr, haloalkyl, C3-C6 halocycloalkyl, Ci-Cr, alkoxy and Ci-Cr, haloalkoxy;

R11 is a 5- membered non-aromatic heterocyclyl ring attached to N of R1 through C atom; said heterocyclyl ring comprises two hetero atoms selected from N and O; and one or more C of the heterocyclyl ring may be optionally replaced with C(=0); said heterocyclyl ring may be optionally substituted with one or more R16a;

R16a and R16b is selected from the group of consisting of hydrogen, halogen, cyano, nitro, hydroxy, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalky l-Ci-Cr, alkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy-C i-Cr, alkyl, Ci-Ce hydroxyalkyl, C2-C6 haloalkenyl, C2-C6 haloalkynyl, C3-C6 halocycloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce haloalkoxycarbonyl, Ci- Cr, alkylthio, Ci-Ce haloalkylthio, Ci-Ce haloalkylsulfinyl, Ci-Ce haloalkylsulfonyl, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulfonyl, Ci-Ce alkylamino, C 1 -Cr, dialkylamino, C3-C6 cycloalkylamino, Ci-Ce alkyl-C3-C6-cycloalkylamino, C 1 -Cr, alkylcarbonyl, Ci-Ce alkoxycarbonyl, Ci-Ce alkylaminocarbonyl, Ci-Ce dialkylaminocarbonyl, Ci-Ce alkoxycarbonyloxy, Ci-Ce alkylaminocarbonyloxy, Ci-Ce dialkylaminocarbonyloxy and Ci-Ce trialkylsilyl; wherein, R16a and R16b may be optionally further substituted with Ci-Ce alkyl, C3-C8 cycloalkyl, Ci-Ce alkoxy, and Ci-Ce alkoxy-Ci-Ce alkyl;

W1 and W2 are independently O or S;

Two R3 together with the carbon atoms to which they are attached may form a 5- to 11-membered carbocycle, or heterocyclyl ring or ring system which may be optionally substituted with R2;

each of R2 and R3 are independently selected from the group consisting of hydrogen, halogen, cyano, nitro, hydroxy, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy-Ci-Ce alkyl, Ci-Ce hydroxyalkyl, C2-C6 haloalkenyl, C2-C6 haloalkynyl, C3-C6 halocycloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce haloalkoxycarbonyl, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce haloalkylsulfinyl, Ci-Ce haloalkylsulfonyl, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulfonyl, Ci-Cr, alkylamino, Ci-Ce dialkylamino, C3-C6 cycloalkylamino, Ci-Ce alkyl-C3-C6-cycloalkylamino, Ci-Ce alkylcarbonyl, Ci-Ce alkoxycarbonyl, Ci-Ce alkylaminocarbonyl, Ci-Ce dialkylaminocarbonyl, Ci-Ce alkoxycarbonyloxy, Ci-Ce alkylaminocarbonyloxy, Ci-Ce dialkylaminocarbonyloxy, Ci-Ce trialkylsilyl, amino, formyl, C2-C6 cyanoalkenyl, phenylcarbonylamino, and phenyloxycarbonyl; wherein each of R2 and R3 may optionally be substituted with halogen, cyano, nitro, hydroxy, Ci-Cr, alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, C 1 -Cr, haloalkyl, Ci-Ce alkoxy-Ci-Ce alkyl, Ci-Ce hydroxyalkyl, C2-C6 haloalkenyl, C2-C6 haloalkynyl, C3-C6 halocycloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Cr, haloalkylsulfinyl, Ci-Ce haloalkylsulfonyl, C 1 -Cr, alkylsulfinyl, C 1 -Cr, alkylsulfonyl, C 1 -Cr, alkylamino, Ci-Ce dialkylamino, C3-C6 cycloalkylamino, Ci-Ce alkyl-C3-C6 cycloalkylamino, Ci-Ce alkylcarbonyl, Ci-Ce alkoxycarbonyl, Ci-Ce alkylaminocarbonyl, Ci-Ce dialkylaminocarbonyl, Ci-Ce alkoxycarbonyloxy, Ci-Ce alkylaminocarbonyloxy, Ci-Ce dialkylaminocarbonyloxy and Ci-Ce trialkylsilyl; or

Each of R2 and R3 are independently selected from the group consisting of phenyl, benzyl, phenoxy or 4- to 6- heterocyclyl; each phenyl, benzyl, phenoxy or 4- to 6- heterocyclyl may optionally be substituted with one or more substituent selected from halogen, cyano, nitro,

hydroxy, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, C i -Cr, alkoxy-Ci-Ce alkyl, C i -Cr, hydroxyalkyl, C2-C6 haloalkenyl, C2-C6 haloalkynyl, C3-C6 halocycloalkyl, Ci-Ce alkoxy, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce haloalkylsulfinyl, Ci-Ce haloalkylsulfonyl, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulfonyl, Ci-Ce alkylamino, Ci-Ce dialkylamino, C3-C6 cycloalkylamino, Ci-Ce alkyl-C3-C6-cycloalkylamino, Ci-Ce alkylcarbonyl, Ci-Ce alkoxycarbonyl, Ci-Ce alkylaminocarbonyl, Ci-Ce dialkylaminocarbonyl, C i -Cr, alkoxycarbonyloxy, Ci-Ce alkylaminocarbonyloxy, Ci-Ce dialkylaminocarbonyloxy, Ci-Ce trialkylsilyl, 2-, 3- or 4 pyridylcarbonylamino which can be mono-, di- or tri- substituted by halogen, cyano, nitro, hydroxy, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl-Ci-Ce alkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy-Ci-Ce alkyl, C i -Cr, hydroxyalkyl, C2-C6 haloalkenyl, C2-C6 haloalkynyl, C3-C6 halocycloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce haloalkylsulfinyl, Ci-Ce haloalkylsulfonyl, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulfonyl, Ci-Ce alkylamino, Ci-Ce dialkylamino, C3-C6 cycloalkylamino, Ci-Ce alkyl-C3-C6 cycloalkylamino, Ci-Ce alkylcarbonyl, C i -Cr, alkoxycarbonyl, Ci-Ce alkylaminocarbonyl, Ci-Ce dialkylaminocarbonyl, Ci-Ce alkoxycarbonyloxy, Ci-Ce alkylaminocarbonyloxy, Ci-Ce dialkylaminocarbonyloxy, Ci-Ce trialkylsilyl, Ci-Ce alkoxycarbonylamino, Ci-Ce alkylaminocarbonylamino, Ci-Ce dialkylaminocarbonylamino, C i-Cr, haloalkylcarhonyl and RxON=C(Ry)-,

Rx and Ry independently are hydrogen or C Cr, alkyl;

“m” is an integer ranging from 0 to 3 ;

R4 is selected from the group consisting of hydrogen, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, Ci-Ce alkylcarbonyl and Ci-Ce alkoxycarbonyl; each of Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, Ci-Ce alkylcarbonyl, Ci-Ce alkoxycarbonyl may be optionally substituted by one or more substituents selected from halogen nitro, cyano, hydroxy, C i -Cr, alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulfonyl, Ci-Ce alkylamino, Ci-Ce dialkylamino, C3-C8 cycloalkyl, C3-C6 cycloalkylamino and Ci-Ce alkyl-C3-Ce cycloalkylamino;

D is selected from the group consisting of;

wherein;

the bond on the right is attached to Z1 and the bond on the left is attached to carbon marked with 2; or the bond on the right is attached to Z1 and the bond on the left is attached to carbon marked with 2; and

R8 and R9 may be attached to one or more possible position/s,

R8 is selected from the group consisting of hydrogen, Ci-Ce alkyl, C3-C8 cycloalkyl, C3- Cs cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, halogen, cyano, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkoxycarbonyl, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulfonyl, Ci-Ce haloalkylsulfinyl and Ci-Ce haloalkylsulfonyl;

R9 is selected from a phenyl ring, a benzyl ring, a 5- or 6-membered aromatic or heteroaromatic ring, a naphthyl ring system, an 8-, 9- or 10-membered fused heterobicyclic ring system, each ring or ring system optionally substituted with at least one substituent independently selected from the group consisting of halogen, Ci-Ce alkyl, C2-C4 alkenyl, C2-C4 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, C2-C4 haloalkenyl, C2-C4 haloalkynyl, C3-C6 halocycloalkyl, cyano, nitro, Ci- Cr, alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkoxycarbonyl, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulfonyl, Ci-Ce haloalkylsulfinyl, Ci-Ce haloalkylsulfonyl, Ci-Ce alkylamino, Ci-Cs dialkylamino, Ci-Ce cycloalkylamino, C3-C8 cycloalkyl-Ci-Ce-alkly amino, Ci-Ce alkylcarbonyl, Ci-Ce alkoxycarbonyl, Ci-Ce alkylaminocarbonyl, Ci-Cs dialkylaminocarbonyl and Ci-Ce trialkylsilyl;

7} is a direct bond or CR6R7 or C(O) or NR18 or O or S(0)o-2;

R6 and R7 are independently selected from the group consisting of hydrogen, halogen, cyano, hydroxy, formyl, Ci-Ce alkyl, C2-C4 alkenyl, C2-C4 alkynyl, Ci-Ce haloalkyl, C2- C4 haloalkenyl, C2-C4 haloalkynyl, Ci-Ce alkoxy-Ci-Ce alkyl, Ci-Ce alkylthioalkyl, Ci-Ce alkylsulfinylalkyl, Ci-Ce alkylsulfonylalkyl, Ci-Ce alkylcarbonyl, Ci-Ce haloalkylcarbonyl, Ci-Ce alkoxycarbonyl, Ci-Ce alkoxycarbonyl-Ci-Ce -alkyl, Ci-Ce alkylaminocarbonyl, C1-C5 dialkylaminocarbonyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy, C3- Cs cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci-Ce alkylsulfinyl, Ci-Ce haloalkylsulfinyl, Ci-Ce alkylsulfonyl and Ci-Ce haloalkylsulfonyl;

R18 and R19 is selected from the group consisting of hydrogen, halogen, cyano, hydroxy, formyl, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci- Cr, alkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy-Ci-Ce alkyl, Ci-Ce hydroxyalkyl, C2-C6 haloalkenyl, C2-C6 haloalkynyl, C3-C6 halocycloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy, C 1 -CVal ky lcarbony I, Ci-Ce haloalkoxycarbonyl, Ci-Ce alkylthio, Ci-Ce haloalkylthio, Ci- Cr, haloalkylsulfinyl, Ci-Ce haloalkylsulfonyl, Ci-Ce alkylsulfinyl and Ci-Ce alkylsulfonyl;

E is selected from the group consisting of hydrogen, halogen, cyano, Ci-Ce alkyl, C3-C6 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy and 3-or 4- membered heterocyclyl ring; said heterocyclyl ring comprise one or more hetero atoms selected from N, O and S (0)0-2; and one or more C of the heterocyclyl ring or ring system may be replaced with C(=0), C(=S) or C(=NR19); said heterocyclyl ring may be optionally substituted with one or more R16b;

or salts, metal complexes, N-oxides, isomers or polymorphs thereof;

provided that the following compounds are excluded from the definition of Formula I,

l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((4,5-dihydrothiazol-2-yl)carbamoyl)-6-methylphenyl)-3- ((5-(perfluoroethyl)-2H-tetrazol-2-yl)methyl)-lH-pyrazole-5-carboxamide;

N-(4-chloro-2-((4,5-dihydrothiazol-2-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3- ((5-(perfluoroethyl)-2H-tetrazol-2-yl)methyl)-lH-pyrazole-5-carboxamide;

l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((4,5-dihydrothiazol-2-yl)carbamoyl)-6-methylphenyl)-3- ((5-(trifluoromethyl)-2H-tetrazol-2-yl)methyl)-lH-pyrazole-5-carboxamide; and

N-(4-chloro-2-((4,5-dihydrothiazol-2-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3- ((5-(trifluoromethyl)-2H-tetrazol-2-yl)methyl)-lH-pyrazole-5-carboxamide.

2. The compound according to claim 1, wherein

R1 is NR10RU;

R10 is selected from the group consisting of hydrogen, C1-C4 alkyl, C3-C8 cycloalkyl, and C3-C8 cycloalkyl-Ci-Ce alkyl;

R16a is selected from the group consisting of hydrogen, halogen, Ci-Ce alkyl, C3- Cs cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-C e halo alkyl, Ci-Ce alkoxy-Ci-Ce alkyl, Ci-Ce alkylcarbonyl and Ci-Ce alkylsulfonyl;

W1 and W2 are O;

R3 is selected from the group consisting of hydrogen, halogen, cyano, nitro, hydroxy, Ci-Ce alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce alkyl-C3-Cs, cycloalkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkylthio, and Ci-Ce haloalkylthio;

“m” is an integer ranging from 0 to 2;

R4 is selected from the group consisting of hydrogen, Ci-Ce alkyl and C3-C8 cycloalkyl;

D is

D4

wherein;

the bond on the right is attached to Z1 and the bond on the left is attached to carbon marked with 2; and

R8 is selected from the group consisting of hydrogen, C1-C4 alkyl, C3-C5 cycloalkyl, halogen, cyano, C1-C4 alkoxy, C1-C4 haloalkoxy and C1-C4 alkylthio;

R9 is selected from a phenyl ring, a benzyl ring, a 5- or 6-membered heteroaromatic ring, each ring or ring system optionally substituted with one or more substituent independently selected from the group consisting of halogen, Ci-Ce alkyl, Ci-Ce haloalkyl, cyano and nitro;

7} is a direct bond or CR6R7 or O;

R6 and R7 are independently selected from the group consisting of hydrogen, halogen, cyano, hydroxy, formyl, C1-C4 alkyl and C1-C4 haloalkyl;

E is selected from the group consisting of hydrogen, halogen, cyano, Ci-Ce alkyl, C3-C6 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy and C3-C6 heterocyclyl; said heterocyclyl ring comprise one or more hetero atoms selected from N, O and S(0)o-2; and one or more C of the heterocyclyl ring or ring system may be replaced with C(=0), C(=S) or C(=NR19); said heterocyclyl ring may be optionally substituted with one or more substituents selected from the group consisting of hydrogen, halogen, cyano and nitro; or

E is 5- or 6- membered heteroaromatic ring, wherein the heteroatoms in heteroaromatic ring may be selected from one or more N, O and S; and heteroaromatic ring may be optionally substituted with hydrogen, Ci-Ce alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-Ci-Ce alkyl, Ci-Ce haloalkyl, C3-Cr, halocycloalkyl, halogen, cyano, carboxyl, aminocarboxyl nitro, hydroxy, Ci-Ce alkoxy, Ci-Ce haloalkoxy, Ci-Ce alkylthio, Ci-Ce alkylsulfinyl, Ci-Ce alkylsulphonyl, Ci-Ce haloalkylthio, Ci-Ce haloalkylsulfinyl and C i - C r, h a I o a I k y I s u I f o n y I .

3. The compound according to claim 1, wherein

R11 is selected from the group consisting of

R3 is selected from the group consisting of hydrogen, halogen, cyano and C1-C4 alkyl;

R4 is hydrogen;

D is

D4-1

wherein;

the bond on the right is attached to Z1 and the bond on the left is attached to carbon marked with 2; and

R8 is hydrogen;

R9 is a 5- or 6-membered heteroaromatic ring optionally substituted with one or more halogen;

E is selected from the group consisting of halogen, cyano, Ci-Ce alkyl, C3-C6 cycloalkyl, C3-C8 cycloalkyl-Ci -Cr, alkyl, Ci-Ce haloalkyl, Ci-Ce alkoxy, Ci-Ce haloalkoxy and C3-C6 heterocyclyl; said heterocyclyl ring comprise one or more hetero atoms selected from N, O and S(0)o-2; said heterocyclyl ring may be optionally substituted with one or more halogen.

4. The compound as claimed in claim 1, wherein said compound of formula (I) is selected from 3- bromo-N-(4-chloro-2-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3- chloropyridin-2-yl)-lH-pyrazole-5 -carboxamide; 3-bromo-N-(4-chloro-2-methyl-6-((3-oxo-2- (2,2,2-trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole- 5-carboxamide; 3-bromo-N-(4-chloro-2-((2-(cyclopropylmethyl)-3-oxoisoxazolidin-4- yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4- chloro-2-((2-(cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3- chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-methyl-6- ((3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5- carboxamide; N-(4-chloro-2-methyl-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidin-4- yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(4- chloro-2-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)- 3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((3-oxo-2-(2,2,2- trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2- trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-(cyclopropylmethyl)-3- oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2- trifluoroethoxy)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-(2,2- difluoroethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole- 5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-ethyl-3-oxoisoxazolidin-4- yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2- (2,2-difluoroethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)- 3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2- (cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH- pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-methyl-6-(( 1 -methyl-3-oxopyrazolidin-4- yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2- methyl-6-((l-methyl-3-oxopyrazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2- trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((l-methyl-3- oxopyrazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5- carboxamide; 3-bromo-N-(4-chloro-2-((2-(2,2-difluoroethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)- 6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4- chloro-6-((l-methyl-3-oxopyrazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-

pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5 -carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyr azole-5-carboxamide; 3-bromo-N-(4-chloro-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((l-methyl-3-oxopyrazolidin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-(methylsulfonyl)isoxazolidin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-methyl-6-((2-(methylsulfonyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-(methylsulfonyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-(methylsulfonyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-(ethylsulfonyl)isoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-((2- (ethylsulfonyl)isoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-(ethylsulfonyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-(ethylsulfonyl)isoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-((2-acetylisoxazolidin-4-yl)carbamoyl)-6-bromo-4-chlorophenyl)-3-bromo-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(2-((2-acetylisoxazolidin-4-yl)carbamoyl)-4-chloro-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyr azole-5 -carboxamide; N-(2-((2-acetylisoxazolidin-4-yl)carbamoyl)-4-chloro-6-methylphenyl)-3-bromo-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(2-((2-acetylisoxazolidin-4-yl)carbamoyl)-4-chloro-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-((2-acetylisoxazolidin-4-yl)carbamoyl)-4-cyano-6-methylphenyl)-3-bromo-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-propionylisoxazolidin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-propionylisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-propionylisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; 3-

bromo-N-(2-bromo-4-chloro-6-((2-propionylisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5 -carboxamide; 3-bromo-N-(4-chloro-2-methyl-6-((2-propionylisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-(methylsulfonyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2- (ethylsulfonyl)isoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyr azole-5 -carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(4-chloro-2-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5 -carboxamide; N-(4-chloro-2-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-lH-pyr azole-5 -carboxamide; N-(4-chloro-2-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)- 1 -(3 -chloropyridin-2-yl)- lH-pyrazole-5 -carboxamide; N-(2-bromo-4-chloro-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyr azole-5 -carboxamide; N-(2-bromo-4-chloro-6-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-methyl-6-((2-methyl-3-

oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-lH-pyrazole-5-carboxamide; 3-bromo-N-(2-bromo-4-chloro-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole-5-carboxamide; N-(4-chloro-2-((2-(cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-3 - (triflu oromethy 1)- 1 H-pyr azole-5 -carboxamide; N -(2-bromo-4 -chlor o-6-( (2- (cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-(2-ethoxyethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidm-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2-(cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; N-(2-bromo-4-chloro-6-((2- (cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-1 H-pyr azole-5 -carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-(cyclopropylmethyl)-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-lH-pyrazole-5-carboxamide; rac-(R)-3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-lH-pyrazole-5-carboxamide; rac-(R)-N-(2-bromo-4-chloro-6-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3 -chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; rac-(R)-N-(2-bromo-4-chloro-6-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; rac-(R)-N-(2-bromo-4-chloro-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-

carboxamide; rac-(R)-N-(2-bromo-4-chloro-6-((2-methyl-3-oxoisoxazolidin-4- yl)carbamoyl)phenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; rac-(R)- 3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4- yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; rac-(R)-3-bromo-N-(4-chloro-2-methyl-6- ((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)- 1 -(3-chloropyridin-2-yl)- IH-pyr azole-5 - carboxamide; rac-(R)-l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-methyl-3- oxoisoxazolidin-4-yl)carbamoyl)phenyl)-3-(thietan-3-yloxy)-lH-pyrazole-5 -carboxamide; rac- (R)-N-(4-chloro-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3- chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; rac-(R)-3-bromo-N-(4-chloro-2-((2- ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-l-(3-chloropyridin-2-yl)-lH-pyrazole- 5-carboxamide; rac-(R)-N-(4-chloro-2-((2-ethyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6- methylphenyl)-l-(3-chloropyridin-2-yl)-3-methoxy-lH-pyrazole-5-carboxamide; rac-(R)-3- bromo-N-(4-chloro-2-methyl-6-((3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-l-(3-chloropyridin- 2-yl)-lH-pyrazole-5-carboxamide; rac-(R)-3-bromo-l-(3-chloropyridin-2-yl)-N-(4-cyano-2- methyl-6-((3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; l-(3- chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-methyl-3-oxoisoxazolidin-4- yl)carbamoyl)phenyl)-3-methoxy-lH-pyrazole-5-carboxamide; l-(3-chloropyridin-2-yl)-N-(4- cyano-2-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-3-methoxy-lH- pyrazole-5-carboxamide; l-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-((2-methyl-3- oxoisoxazolidin-4-yl)carbamoyl)phenyl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-isopropyl-3-oxoisoxazolidin-4-yl)carbamoyl)-6- methylphenyl)-3-(2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; l-(3-chloropyridin-2-yl)- N-(4-cyano-2-methyl-6-((3-oxo-2-(2,2,2-trifluoroethyl)isoxazolidin-4-yl)carbamoyl)phenyl)-3- (2,2,2-trifluoroethoxy)-lH-pyrazole-5-carboxamide; 3-bromo-l-(3-chloropyridin-2-yl)-N-(2,4- dichloro-6-((3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-lH-pyrazole-5-carboxamide; l-(3- chloropyridin-2-yl)-N-(2,4-dichloro-6-((3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-3- (trifluoromethyl)-lH-pyrazole-5-carboxamide; rac-(R)-l-(3-chloropyridin-2-yl)-N-(2,4-dichloro- 6-((3-oxoisoxazolidin-4-yl)carbamoyl)phenyl)-3-(3,3-difluoroazetidin-l-yl)-lH-pyrazole-5- carboxamide and l-(3-chloropyridin-2-yl)-N-(4-cyano-2-((2-(cyclopropylmethyl)-3- oxoisoxazolidin-4-yl)carbamoyl)-6-methylphenyl)-3-methoxy-lH-pyrazole-5-carboxamide.

5. A compound of formula (I) or salts, metal complexes, N-oxides, isomers, or polymorphs thereof according to claim 1 in a biologically effective amount in a composition comprising at least one additional component selected from the group consisting of surfactants and auxiliaries for controlling or preventing insects and/or mite pestsof .

6. The compound of formula (I) or salts, metal complexes, N-oxides, isomers, or polymorphs thereof according to claim 1 in a biologically effective amount in a compositionfor agricultural and/or veterinary applications.

7. The compound according to claim 5, wherein said composition additionally comprises at least one additional biological active compatible compound selected from fungicides, insecticides, nematicides, acaricides, biopesticides, herbicides, plant growth regulators, antibiotics, fertilizers or nutrients.

8. A combination comprising biologically effective amount of compound of formula (I) or salts, metal complexes, N-oxides, isomers or polymorphs thereof according to claim 1 and at least one additional biological active compatible compound selected from fungicides, insecticides, nematicides, acaricides, biopesticides, herbicides, plant growth regulators, antibiotics, fertilizers or nutrients.

9. The compound or combination according to claim 5 or 8, wherein said biologically effective amount of compound of formula (I) ranges from 0.1 % to 99% by weight with respect to the total weight of the composition, preferably ranges from 5 to 50% by weight with respect to the total weight of the composition.

10. A compound of formula (I) or salts, metal complexes, N-oxides, isomers, polymorphs, composition or combination thereof according to claim 1 or 5 or 8 for combating insects and mite pests by contacting the insects and mite pests, their habit, breeding ground, food supply, plant, seed, soil, area, material or environment in which the insect and mite pests are growing or may grow, or the materials, plants, seeds, soils, surfaces or spaces to be protected from pest attack or infestation with a biologically effective amount of said compound or said composition or said combination.

11. A method for protecting crops from attack or infestation by insects and mite pests comprises contacting the crop with a biologically effective amount of the compound or salts, metal

complexes, N-oxides, isomers, polymorphs, composition or combination thereof according to claim 1 or 5 or 8.

12. The method according to claim 11, wherein said method comprises applying effective dosages of compound of formula (I) in amounts ranging from 1 gai to 5000 gai per hectare in agricultural or horticultural crops.

13. A method for the protection of seeds from soil insects and of the seedlings roots and shoots from soil and foliar insects comprising contacting the seeds before sowing and/or after pre-germination with the compound of formula (I) or salts, metal complexes, N-oxides, isomers, polymorphs, composition or combination thereof according to claim 1 or 5 or 8.

14. A compound of formula (I) or salts, metal complexes, N-oxides, isomers, polymorphs, composition or combination thereof according to claim 1 or 5 or 8 for treating or protecting animals against infestation or infection by parasites which comprises orally, topically or parenterally administering or applying to the animals a biologically effective amount of said compound or said composition or said combination.

15. The compound of formula (I) or salts, metal complexes, N-oxides, isomers, polymorphs, or combination thereof according to claim 1 or 5 or 8 in a composition for combating insects and mite pests in agricultural crops and/or horticultural crops or parasites on animals.

16. The compound of formula (I) according to claim 15in the medicament for treating or protecting animals against infestation or infection by insect and mite pests or parasites.

17. The use of the compound of formula (I) according to claim 15, wherein said agricultural crops are cereals, corn, rice, soybean and other leguminous plants, fruits and fruit trees, grapes, nuts and nut trees, citrus and citrus trees, any horticultural plants, cucurbitaceae, oleaginous plants, tobacco, coffee, tea, cacao, sugar beet, sugar cane, cotton, potato, tomato, onions, peppers, other vegetables and ornamentals.

18. A seed comprising a compound of formula (I) or salts, metal complexes, N-oxides, isomers, polymorphs, composition or combination thereof according to claim 1 or 5 or 8, wherein the

amount of compound of formula (I) in said seed ranging from about 0.0001% to about 1% by weight.

19. A process for preparing compound of formula (I) according to claim 1, wherein said process comprising the steps of:

a) reacting compound of formula (i) with compound of formula (ii) to afford the compound of formula (I);

wherein, W1, W2, D, E, Z1, R1, R3, R4 and m are as defined in Claim 1.

20. A compound of formulae la or lb;

or

wherein, R16 is N(R4)2 or nitro; W1, W2, D, R1, R3, R4, R16a and m are as defined in claim 1, with the

proviso that R1 in la is not NHRU-1, wherein Ru-1 is