Field of the Invention
This invention relates to Anti-counterfeit Primary packaging used by Pharmaceutical industry
with hologram transfer aluminum foil and in particular, thisinvention relates to an anti-
counterfeit hologram transfer aluminum foil wherein hologram is transferred to the
surface of Aluminum foil. Furthermore the invention also relates to thehologram transfer
aluminum foil in which two, three or four layered structure of various substrates were
present with Aluminum foil as one essential layer. This invention relates to the process of
manufacturing the hologram transfer aluminum foil for primary packaging for the
pharmaceutical products.
Background of the invention and the related Prior Art
In a typical application taking full advantage of the aforesaid features of
volume holograms, a hologram adhesive label, obtained in a film form with an
adhesive attached thereto, is applied to a variety of associated members. For
instance, JP-A-63-284586 discloses a transfer type hologram of a multilayer
structure comprising a substrate, a volume hologram layer and a heat seal layer
in this order. In view of illegal copying using a relief hologram, for instance,
Japanese Patent No. 2,934,281 shows a transfer type hologram of a multilayer
structure comprising a substrate, a relief hologram layer and a heat seal layer in
this order.
In the former,.however, the volume hologram layer is basically made up of a

photocured resin layer whereas the associated member is formed of high-
quality paper or the like.. Such a.material difference often makes it difficult to
. select a heat sealing agent showing satisfactory adhesion with respect to both
materials, and so this label is applied to only a limited number of application
members although depending on the heat sealing agent used. For this reason,
the hologram layer peels off at an interface between the volume hologram layer
and the heat seal layer or the heat seal layer and the application member,
resulting in a high risk of illegal copying. A problem with the latter is that
characters, images or the like on the application members cannot be seen
through.
In view of prevention of illegal copying, the volume hologram layer must have
good adhesion to the application member, and one approach to improvements
in the adhesion between a volume hologram layer and an application member is
typically set forth in JP-A-2002-358018 showing that the volume hologram
layer and the application member are bonded together via a plurality of heat
seal layers, and exemplifying a polyvinyl chloride or polyester resin sheet as
the application member. However, the polyvinyl chloride sheet offers an
environmental pollution problem arising from the generation of dioxin, etc.
upon incineration and disposal. In recent years, therefore, the use of polyester
resin sheets as application members has grown. Still, polyester resin sheets are

lesser adhesive than polyvinyl chloride cards, and there is insufficient adhesion
to the volume hologram layer, especially a volume hologram layer comprising
a photocation type monomer and a photoradical type monomer, often offering a
problem in conjunction with illegal copying. Multiple heat seal layers are
unfavorable for fabrication, and so it is desired that the volume hologram layer
and the application member be bonded together via a single-layer heat seal
layer. What is especially in need is the development of a heat seal layer fit for
the use of a polyester resin sheet as an application member.
Aluminium foil is a preferred substrate and used extensively for the packing of
medicines and related products as well in the food and FMCG industry.
Keeping in mind the critical nature of usage ,the manufacturing process of
aluminium foil and aluminium foil based laminate is controlled through a series
of controlled stages and numerous process control points so that the output is of
the desired quality requirements.
The demand for counterfeit-proof packaging material, for example for
medications, has grown in recent years to the extent the amount of counterfeit
medications has risen relatively greatly worldwide. These counterfeits can be
pharmaceutically active drugs, but also agents with a placebo effect.

Therefore the. attempt is made, to provide packaging materials for the
pharmaceutical industry with holograms. It has been found that even
holograms, although their production is relatively complicated, can be
counterfeited with increasing technical development. These counterfeits can
only be characterized or recognized as such by a specialist since it is difficult
for the user of a medication to ascertain whether the hologram is counterfeit or
not if he does not have the corresponding comparison specimen.
The document CN2583020relates to aluminum and paper composite aluminum
foil paper for cigarette package, which comprises a layer of lining paper and a
layer of aluminum foil, wherein, the lining paper and the aluminum foil are
compounded together; a laser layer is partially compounded on the aluminum
foil. A laser counterfeit-proof aluminum foil paper provided by the utility
model not only reserves all the advantages and characteristics Of original
aluminum foil paper, but also has the functions of counterfeit proof, etc. The
appearance of the laser counterfeit-proof aluminum foil paper has temporal
spirit. In addition, the laser layer is partially compounded on a required
position, which effectively saves resources.
The other document EP0149180 describes the lid-plate is made of a laminate
which is.composed of an aluminium foil and at least one layer of plastic, for

sealing onto plastic surfaces. The layer of plastic consists of an EVA-PE
mixture, and the plate is embossed in order to achieve a flat lie. The preferred
embossing pattern is a linendesign.
The patent document CN201103077states a composite aluminium-foil paper
combined aluminium and paper and used for cigarette packaging. The
composite aluminium-foil paper comprises a layer of lining paper and a layer of
aluminium foil, which are compounded as a whole; the upper local part of the
. aluminium foil is overlapped with a laser layer. The three-dimensional laser
hologram aluminium-foil anti-counterfeiting paper provided by the utility
model not only has the advantages and characteristics of freshness preservation
and moisture resistance, but also has the functions of anti-counterfeiting with
stereoscopic impression; in addition, the design proposal of the structure that a
required.part is partially or wholly overlapped with a three-dimensional laser
hologram layer results in effective control of production cost, resources
conservation and enhance anti-counterfeiting of products.
The other document JP2010240994 discloses a composite aluminum-foil paper
combined aluminum and paper and used for cigarette packaging. The
composite aluminum-foil paper comprises a layer of lining paper and a layer of
aluminium foil, which are compounded as a whole; the upper local part of the

aluminium foil is overlapped with a laser layer. The three-dimensional laser
hologram aluminium-foil anti-counterfeiting paper provided by the utility
model not only has the advantages and characteristics of freshness preservation
and moisture resistance, but also has the. functions of anti-counterfeiting with
stereoscopic impression; in addition, the design proposal of the structure that a
required part is partially or wholly overlapped with a three-dimensional laser
hologram layer results in effective control of production cost, resources
conservation and enhance anti-counterfeiting of products.
According to the document JP2012063486 a composition for volumehologram
layer formation with which a volumehologram layer with a superior foil cutting
property is formed. The composition for volumehologram layer formation
contains a cationpolymerizable compound having a cationpolymerizable
functional group and a radical polymerizable compound having a radical
polymerizable functional group, and is used to form the. volumehologram
layer having a volumehologram recorded, and is characterized in decreasing
breaking strength of the volumehologram layer and in containing the
cationpolymerizable compound having the cationpolymerizable functional
group.

The invention of the document US2014016167 providesa major object of the
present invention is to provide a volumehologram transfer foil that gives a
volumehologram laminate higher in anti-forgery function. The present
invention achieves the object by providing a volumehologram transfer foil
comprising: a substrate, a volumehologram layer carrying a recorded .
volumehologram that is formed on the substrate, and an image forming layer
carrying a formed image and a heat seal layer containing a thermoplastic resin
that are formed on the volume hologram layer, and comprising no
reflectivelayer having a function to reflect light.
According to the invention 2714/MUM/2009a packaging material comprising a
plurality of layers, said material having discernible indicia for authentication
characterized by the presence of at least one predetermined anti-counterfeit
feature at, at least one predetermined location in at least one predetermined
visible layer. Also, provided in accordance with the.present invention is a
process for manufacturing said packaging material.
A method for producing ahologram label and ahologram transfer foil in which
ahologram effect can be eliminated in a heated part by heating. The method for
producing ahologram label in which ahologram effect disappears in a heated

part by heating includes: (1) a substrate preparation step;2) a step of forming an
ionization radiation curable resinlayer; (3) a step of forming ahologramlayer in
a cured state by imparting a fine concavo-convex pattern to a surface of the
ionization radiation curable resinlayer and then irradiating thelayer with UV
rays; (4) a step of forming a reflectionlayer that follows the fine concavo-
convex pattern by printing a surface of thehologram layer with a silver-color
ink by a printing process and drying the ink at a temperature of 40 DEG C or
lower; and (5) a step of forming ahologram label by applying and drying an
adhesive composition on a surface of the reflectionlayer to form an
adhesive layer and release by laminating a release sheet thereonwhich has been
stated in document of patent application JP2014092647.
The document US2015036198 states that thehologram transfer foil according to
an embodiment is thermally transferrable to a transfer base member.
Thehologram transfer foil has a structure configured such that a peelinglayer, a
diffraction structure forminglayer and ah adhesivelayer are stacked on one
surface of a substrate the diffraction structure forminglayer includes fine
concaves and convexs of ahologram or a diffraction grating. At least one of the
peelinglayer and the adhesivelayer includes heat-conductive hidden
information in a heat-conductive hidden information possession portion.

he other document JP2010099929 provide a security film and a transfer foil
which have a surface-relief-typehologram having unique design and a high
forgery-proof effect. The security film has at least a
firsthologram forminglayer, a first reflection layer, a
secondhologram forming layer and a second reflection layer, piled up in this
order on one side of a support 1, and the first reflection layer is present
partially. There is also provided the transfer foil in which a release layer is
formed between the support and the firsthologram forming layer of the security
film and an adhesive layer is formed on the second reflection.
The document JP2009241406 discloses a transfer foil for in-molding having a
fluorescenthologramwhich has such heat resistance that whitening is not caused
by heat, is excellent in followability to expansion and contraction, reduced in
cracking and whitening and excellent in heat resistance and light resistance and
to provide a molded article using the transfer foil for in-molding. The transfer
foil for in-molding comprises a base material, a mold-released layer, ahologram
layer, a transparent reflecting layer, a high luminance ink layer and an.
adhesive layer. The mold-released layer is a melamine-based resin and
thehologram layer is the fluorescent hologram layer including a hard coat
ionization radiation-curing resin, silicone, a fluorescent rare-earth complex and
a filler. The absorption wavelength region of the ionization radiation curing

resin is different from the absorption wavelength region of the fluorescent rare-
earth complex.
Pharmaceutical industry, both domestic and international, is using 2/3/4
plyaluminium foil laminates for the traditional pouch and other packaging for
obvious reasons and the same is expected to grow @ 12 % per annum for next
5 years. Counterfeits are a major threat for the Pharmaceutical industry and the
public health as well and thus the industry is in constant search for newer and
better Anti-counterfeit options.lt becomes very important to ensure that there is
no pilferage in the interest of the end user and health and safety of the
consumers.
A lot of research work happened in last few years to provide anti-counterfeit
aluminium foil need to be fulfilled for essentially healthcare products which is
clearly understood as priority area.
In the meantime, a further improvement in generalization is desired for a
hologram used for an improvement and for prevention of forgeries in view of
its usefulness. To cope with this desire, the inventors of the present invention
have made an invention concerning a method in which a hologram transfer
aluminium foil is formed continuously in the course of industrial
production.None of these above patents, however alone or in combination,
disclose the present invention. The invention consists of certain novel features

and a combination of parts hereinafter fully described and particularly pointed
out in the appended claims, it being understood that various changes in the
details may be made without departing from the spirit, or sacrificing any of the
advantages of the present invention.
Summary of the invention
This invention relates toAnti-counterfeit Primary packaging used in pharmaceutical industry,
with hologram transfer aluminum foil and in particular, this invention relates to an anti-
counterfeit hologram transfer aluminum foil wherein hologram is transferred to the
surface of Aluminum foil. Furthermore the invention also relates to the hologram transfer
aluminum foil in which two or three or four layered structure of various substrates were
present with Aluminum foil as one essential layer. This invention relates to the process of
manufacturing the hologram transfer aluminum foil for packaging the pharmaceutical
products.
Detailed description of the invention with accompanying drawings
There.are many possible embodiments of this.invention. The drawings and
description below describe in detail a preferred embodiment of the invention.
Those skilled in the art will recognize the following described features and
improvements of the present invention as well as other and further objects,

features, and advantages that will become apparent from the following
description of presently preferred embodiments of the invention given for the
purpose of disclosure.
The present invention has been made in consideration of the above
circumstance, and the object of the invention is to provide a hologram transfer
aluminium foil which is easy to identify and difficult to counterfeit and tamper,
an image display element..
The principal object of the invention is to provideanti-counterfeit Pharma Primary
packaging withhologram transfer aluminum foil.
The other embodiment of the invention is to provide an anti-counterfeit
hologram transfer aluminum foil wherein hologram is transferred to the surface
of Aluminum foil.
The other embodiment of the invention is to provide the anti-counterfeitpharma
primary packaging foil,which is made of aluminium.
The other embodiment of the invention is to provide the hologram transfer
aluminum foil in which two or three or four layered structure of various
substrates were present with Aluminum foil as one essential layer.
Still another object of the present invention is to provide the process of

manufacturing the anti-counterfeit Pharma Primary packaging with hologram
transfer aluminum foil for packaging the pharmaceutical products.
It is a general object of the invention to provide a security object that provides
strong anti-counterfeiting protection and/or that is easy to verify.
Such a hologram, which is difficult to copy, has been used as an anti-forgery
means in various applications; but methods facilitating copying of the hologram
are becoming available recently, and simple use of a hologram is pointed out to
be insufficient as an anti-forgery means. For that reason, there is an increasing
need for a hologram transfer foil that gives a hologram improved in antiforgery
function and thus insecurity.
The aim of the present disclosure is to develop and manufacture thepharma
primary packaging withAluminium foil which has a specific characteristic
maintaining the technical aspects and to protect end used product from the
counterfeiters..
In the hologram transfer aluminum foil15 to 40 micron Aluminium foil were
used for hologram transferred. There are two/ three/ four ply structure were
constructed with various coatings and polymers like PE, PP,PVC,PA, PET etc.

The features and advantages of the present invention will be explored through
the following description and drawings. It should be understood, however, that
the detailed description, while indicating particular embodiments of the
invention, are given by way of illustration only, and various modifications may
naturally be performed without deviatingfrom the spirit of the present
invention.
The fig 1 shows the two ply structure of the hologram transfer aluminum foil
according to the invention;
The fig 2 shows the three ply structure of the hologram transfer aluminum foil
according to the invention;
The fig 3 shows the four ply structure of the hologram transfer aluminum foil
according to the invention;
The fig 4 shows the flow chart of the process of manufacturing the hologram
transfer aluminum foil according to the invention;
Transfer of the hologram onto the transfer substrate is very critical and involves
lot of in-process controls to ensure that the required effect is achieved. This
involves high level well defined embossing and transferring the impression on
the substrate to get the desired effect.

The process for preparing ananti-counterfeit Primary packaging withhologram
transfer aluminum foil for pharmaceutical packaging, which comprises a)
down gauging the foil stock from 300 microns to 15-40 microns; b) Separation
and rewinding into smaller rolls is done; c) Annealing of the aluminium foil;d)
Laminating or coating ( two or three or four) of this Foil with various
substrates.
Down gauging the foil stock from 300 microns to 15-40 microns.Aluminium
foil can be sourced as the direct roll to gauge requirement. Rolling of foil stock
on 4Hi cold rolling mill with desired bite and tension is to reduce upto 50%.per
pass. Adjusting the process parameters appropriately and accurately as the
gauge requirement in this product is very critical. The foil undergoes a rolling
cycle through a pre-designed multiple pass program to finally produce the
required gauge within the gauge tolerance limit set. With every pass all the
quality parameters are verified for compliance. The online gauge control
ensures that the gauge is uniformly maintained. The finished pass or the final
pass is done with pack rolling. Subsequently the edges are trimmed and coiling
is done on the re-winder. Separation and rewinding into smaller rolls is done.
Since this foil subsequently undergoes a lamination procedure the foil surface
is very important to main the bond strength and also to give the required
functional parameters compliance.

Annealing is a heat process, whereby a metal is heated to a specific temperature
/colour and then allowed to cool slowly. This softens the metal which means it
can be cut and shaped more easily.
The heat treatment alters the physical and sometimes chemical properties of a
material to increase its ductility and to make it more workable. It involves
heating a material to above its glass transition temperature, maintaining a
suitable temperature, and then cooling. Annealing can induce ductility, soften
material, relieve internal stresses, refine the structure by making it
homogeneous, and improve coldworking properties.
The separated foil from the previous process is loaded onto the holding racks.
The annealing furnace is pre-heated to the desired temperature and then the
loaded racks are placed as per the designated position into the annealing
furnace. The temperature of the annealing furnace is then increased to the
desired temperature. After the cycle is complete then the control panel is put off
and the temperature is brought down. The holding racks are removed from the
furnace and allowed to coil gradually at room temperature.

At the time of lamination of transfer substrate with treated Aluminium foil
without any adhesive the partially annealed foil is corona treated on the
laminator and is fed in the first un-winder. The impression carrying substrate is
loaded on the second uri-winder. The lamination, is conducted in such a way
that the treated foil is in contact with the anti-counterfeit carrying image
substrate. The process is done at a controlled speed.
In the impugned inventionLamination/ coating of this Foil with various
substrates has been done in twoply coated structure wherein the Aluminium foil
with hologram is coated with heat-seal coating on the non-hologram side.
But in two ply laminated structure the Aluminium foil with hologram is
laminated with a sealing polymer film on the non-hologram side. In three ply
structure the Aluminium foil with hologram is placed on the first un-winder and
the transparent polymer of the required gauge is placed on the second un-
winder and Sealing polymer film of the required gauge on the third un-winder.
The adhesive is circulated in both the stations/ glue trays. The web is passed in
such a way that the first surface of Aluminum being coated with adhesive is
hologram holding side and the same is laminated with transparent polymer after
drying. The non-hologram holding side is then coated with the adhesive and
dried before being laminated with sealing polymer.

On the other hand four ply structurethe Aluminium foil with hologram is placed
on the second un-winder and the transparent polymer of the required gauge is
placed on the first un-winder of Extruder laminator. Tie polymer is extruded
and sandwitched between these two layer to bond them and the final sealing
layer is extruded from the second station. The laminate is then wound onto the
re-winder.
COMMERCIAL APPLICABILITY
The process of manufacturing theanti-counterfeit Pharma Primary packaging
withhologram transfer aluminum foil of the instant invention will allow a
tremendous scope in terms of identification and traceability a product available
in the market.
The present invention is not is riot limited to the embodiments above. These
embodiments are presented here only aimed for general description, and any
invention having a configuration substantially identical in technical idea
described in the claims of the present invention and having similar operational
advantages shall also be included in the technological scope of the present
invention.

I claim:
1) Theanti-counterfeit Primary packaging material for pharmaceutical use
withhologram transfer aluminum foilwhich comprises:
i) Hologram transfer Aluminium foil;.
2) The anti-counterfeit Primary packaging material for pharmaceutical
withhologram transfer aluminum foilas claimed in claim 1 in which the
structure of the various substrates with Aluminum foil is two layer or three
layer or four layer.
3) The anti-counterfeit Primary packaging material for pharmaceutical
withhologram transfer aluminum foilas claimed in claim 1 in which the
Aluminium foil is 15 to 40 micron.
4) The process of manufacturing theanti-counterfeit Primary packaging
material for pharmaceutical withhologram transfer aluminum foil which .
comprises
a) Down gauging the foil stock from 300 microns to 15-40 microns
b) Separation and rewinding into smaller rolls is done
c) Annealing of the Aluminium foil, if required, based on specification
d) Lamination of transfer substrate with Treated Aluminium foil without
any adhesive

5) The process of manufacturing theanti-counterfeit Primary packaging
material for pharmaceutical withhologram transfer aluminum foi 1 as
claimed in claim 4 which comprises
a) Down gauging the foil stock from 300 microns to 15-40 microns
b) Separation and rewinding into smaller rolls is done
c) Annealing of the Aluminium foil
d)Laminating or coating of this Foil with various (two or three or four)
substrates with or without adhesive
6) The process of manufacturing theanti-counterfeit Primary packaging material
for pharmaceutical foil as claimed in claim 4 wherein hologram is transferred
to the surface of Aluminum foil.
7) The process of manufacturing the anti-counterfeit Primary packaging material
for pharmaceutical foil as claimed in claim 4 wherein the gauge is
maintaineduniformly.
8) The process of manufacturing theanti-counterfeit Primary packaging material
for pharmaceutical foil as claimed in claim 4 wherein in two ply coated
structure the Aluminium foil with hologram is coated with heat-seal coating
on the non-hologram side.
9) The process of manufacturing the anti-counterfeit Primary packaging material
for pharmaceutical foil as claimed in claim 4 wherein in two ply laminated

structure the Aluminium foil with hologram is laminated with a sealing
polymer film on the non-hologram side.
10)The process of manufacturing theanti-counterfeit Primary packaging material
for pharmaceutical foil as claimed in claim 4 wherein in three ply laminated
or coated structure the Aluminium foil with hologram is placed on the first
un-winder and the transparent polymer of the required gauge is placed on
the second un-winder and Sealing polymer film of the required gauge on the
third un-winder.
1 l)The process of manufacturing theanti-counterfeit Primary packaging material
for pharmaceutical foil as claimed in claim 4 wherein in four ply laminated
or coated structure the Aluminium foil with hologram is placed on the
second un-winder and the transparent polymer of the required gauge is
placed on the first un-winder of. Extruder laminator.