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"Anti Cxcr4 Antibodies And Their Use For The Treatment Of Cancer"

Abstract: The present invention relates to a novel isolated antibody, or the derived compounds or functional fragments of same, capable of binding to CXCR4 but also of inducing conformational changed of the CXCR4 homodimers and/or heterodimers. More particularly, the present invention relates to the 414H5 and 515H7 antibodies, specific to the CXCR4 protein, as well as then-use for the treatment of cancer. Pharmaceutical compositions composed of such antibodies and a process for the selection of such antibodies are also covered.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
26 April 2011
Publication Number
39/2013
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
sna@sna-ip.com
Parent Application

Applicants

PIERRE FABRE MEDICAMENT
45, PLACE ABEL GANCE, F-92100 BOULOGNE-BILLANCOURT, FRANCE

Inventors

1. KLINGUER-HAMOUR, CHRISTINE
73, ROUTE DE CHEZ DIOSSAZ, LES GOTTALLES, F-74570 GROISY, FRANCE
2. GRENIER-CAUSSANEL, VERONIQUE
1 RUE DE LA VIA DE 1'ORME F - 01430 SAINT MARTIN DU FRESNE, FRANCE

Specification

Documents

Orders

Section Controller Decision Date

Application Documents

# Name Date
1 3042-DELNP-2011-Correspondence to notify the Controller [14-09-2020(online)].pdf 2020-09-14
1 3042-delnp-2011-GPA-(12-10-2011).pdf 2011-10-12
2 3042-delnp-2011-Form-1-(12-10-2011).pdf 2011-10-12
2 3042-DELNP-2011-US(14)-ExtendedHearingNotice-(HearingDate-14-09-2020).pdf 2020-08-14
3 3042-DELNP-2011-Response to office action (Mandatory) [06-06-2018(online)].pdf 2018-06-06
3 3042-delnp-2011-Correspondence Others-(12-10-2011).pdf 2011-10-12
4 3042-DELNP-2011-REQUEST FOR ADJOURNMENT OF HEARING UNDER RULE 129A [26-04-2018(online)].pdf 2018-04-26
4 3042-delnp-2011-Form-3-(21-10-2011).pdf 2011-10-21
5 3042-DELNP-2011-Written submissions and relevant documents (MANDATORY) [19-04-2018(online)].pdf 2018-04-19
5 3042-delnp-2011-Correspondence Others-(21-10-2011).pdf 2011-10-21
6 3042-DELNP-2011-HearingNoticeLetter.pdf 2018-04-17
6 3042-delnp-2011-Form-5.pdf 2011-12-23
7 3042-delnp-2011-Form-3.pdf 2011-12-23
7 3042-DELNP-2011-ABSTRACT [10-04-2018(online)].pdf 2018-04-10
8 3042-delnp-2011-Form-2.pdf 2011-12-23
8 3042-DELNP-2011-ABSTRACT [10-04-2018(online)]_93.pdf 2018-04-10
9 3042-DELNP-2011-AMENDED DOCUMENTS [10-04-2018(online)].pdf 2018-04-10
9 3042-delnp-2011-Form-1.pdf 2011-12-23
10 3042-DELNP-2011-Changing Name-Nationality-Address For Service [10-04-2018(online)].pdf 2018-04-10
10 3042-delnp-2011-Drawings.pdf 2011-12-23
11 3042-DELNP-2011-CLAIMS [10-04-2018(online)].pdf 2018-04-10
11 3042-delnp-2011-Description (Complete).pdf 2011-12-26
12 3042-DELNP-2011-CLAIMS [10-04-2018(online)]_77.pdf 2018-04-10
12 3042-delnp-2011-Correspondence Others.pdf 2011-12-26
13 3042-delnp-2011-Claims.pdf 2011-12-26
13 3042-DELNP-2011-COMPLETE SPECIFICATION [10-04-2018(online)].pdf 2018-04-10
14 3042-delnp-2011-Abstract.pdf 2011-12-26
14 3042-DELNP-2011-COMPLETE SPECIFICATION [10-04-2018(online)]_108.pdf 2018-04-10
15 3042-DELNP-2011-DRAWING [10-04-2018(online)].pdf 2018-04-10
15 3042-delnp-2011-Form-18-(03-09-2012).pdf 2012-09-03
16 3042-delnp-2011-Correspondence-others-(03-09-2012).pdf 2012-09-03
16 3042-DELNP-2011-DRAWING [10-04-2018(online)]_103.pdf 2018-04-10
17 3042-DELNP-2011-FER_SER_REPLY [10-04-2018(online)].pdf 2018-04-10
17 3042-delnp-2011-Correspondence Others-(30-11-2012).pdf 2012-11-30
18 3042-DELNP-2011-FER.pdf 2017-07-21
18 3042-DELNP-2011-FER_SER_REPLY [10-04-2018(online)]_66.pdf 2018-04-10
19 3042-DELNP-2011-FORM 3 [10-04-2018(online)].pdf 2018-04-10
19 3042-DELNP-2011-FORM 4(ii) [10-01-2018(online)].pdf 2018-01-10
20 3042-DELNP-2011-Information under section 8(2) (MANDATORY) [10-04-2018(online)].pdf 2018-04-10
20 3042-DELNP-2011-SEQUENCE LISTING [10-04-2018(online)].txt 2018-04-10
21 3042-DELNP-2011-MARKED COPIES OF AMENDEMENTS [10-04-2018(online)].pdf 2018-04-10
21 3042-DELNP-2011-SEQUENCE LISTING [10-04-2018(online)].jpg_102.txt 2018-04-10
22 3042-DELNP-2011-OTHERS [10-04-2018(online)].pdf 2018-04-10
22 3042-DELNP-2011-SEQUENCE LISTING [10-04-2018(online)].jpg 2018-04-10
23 3042-DELNP-2011-PETITION UNDER RULE 137 [10-04-2018(online)].pdf 2018-04-10
23 3042-DELNP-2011-RELEVANT DOCUMENTS [10-04-2018(online)]_33.pdf 2018-04-10
24 3042-DELNP-2011-RELEVANT DOCUMENTS [10-04-2018(online)].pdf 2018-04-10
25 3042-DELNP-2011-RELEVANT DOCUMENTS [10-04-2018(online)]_33.pdf 2018-04-10
25 3042-DELNP-2011-PETITION UNDER RULE 137 [10-04-2018(online)].pdf 2018-04-10
26 3042-DELNP-2011-OTHERS [10-04-2018(online)].pdf 2018-04-10
26 3042-DELNP-2011-SEQUENCE LISTING [10-04-2018(online)].jpg 2018-04-10
27 3042-DELNP-2011-MARKED COPIES OF AMENDEMENTS [10-04-2018(online)].pdf 2018-04-10
27 3042-DELNP-2011-SEQUENCE LISTING [10-04-2018(online)].jpg_102.txt 2018-04-10
28 3042-DELNP-2011-Information under section 8(2) (MANDATORY) [10-04-2018(online)].pdf 2018-04-10
28 3042-DELNP-2011-SEQUENCE LISTING [10-04-2018(online)].txt 2018-04-10
29 3042-DELNP-2011-FORM 3 [10-04-2018(online)].pdf 2018-04-10
29 3042-DELNP-2011-FORM 4(ii) [10-01-2018(online)].pdf 2018-01-10
30 3042-DELNP-2011-FER.pdf 2017-07-21
30 3042-DELNP-2011-FER_SER_REPLY [10-04-2018(online)]_66.pdf 2018-04-10
31 3042-delnp-2011-Correspondence Others-(30-11-2012).pdf 2012-11-30
31 3042-DELNP-2011-FER_SER_REPLY [10-04-2018(online)].pdf 2018-04-10
32 3042-delnp-2011-Correspondence-others-(03-09-2012).pdf 2012-09-03
32 3042-DELNP-2011-DRAWING [10-04-2018(online)]_103.pdf 2018-04-10
33 3042-DELNP-2011-DRAWING [10-04-2018(online)].pdf 2018-04-10
33 3042-delnp-2011-Form-18-(03-09-2012).pdf 2012-09-03
34 3042-delnp-2011-Abstract.pdf 2011-12-26
34 3042-DELNP-2011-COMPLETE SPECIFICATION [10-04-2018(online)]_108.pdf 2018-04-10
35 3042-delnp-2011-Claims.pdf 2011-12-26
35 3042-DELNP-2011-COMPLETE SPECIFICATION [10-04-2018(online)].pdf 2018-04-10
36 3042-delnp-2011-Correspondence Others.pdf 2011-12-26
36 3042-DELNP-2011-CLAIMS [10-04-2018(online)]_77.pdf 2018-04-10
37 3042-DELNP-2011-CLAIMS [10-04-2018(online)].pdf 2018-04-10
37 3042-delnp-2011-Description (Complete).pdf 2011-12-26
38 3042-DELNP-2011-Changing Name-Nationality-Address For Service [10-04-2018(online)].pdf 2018-04-10
38 3042-delnp-2011-Drawings.pdf 2011-12-23
39 3042-DELNP-2011-AMENDED DOCUMENTS [10-04-2018(online)].pdf 2018-04-10
39 3042-delnp-2011-Form-1.pdf 2011-12-23
40 3042-DELNP-2011-ABSTRACT [10-04-2018(online)]_93.pdf 2018-04-10
40 3042-delnp-2011-Form-2.pdf 2011-12-23
41 3042-DELNP-2011-ABSTRACT [10-04-2018(online)].pdf 2018-04-10
41 3042-delnp-2011-Form-3.pdf 2011-12-23
42 3042-DELNP-2011-HearingNoticeLetter.pdf 2018-04-17
42 3042-delnp-2011-Form-5.pdf 2011-12-23
43 3042-DELNP-2011-Written submissions and relevant documents (MANDATORY) [19-04-2018(online)].pdf 2018-04-19
43 3042-delnp-2011-Correspondence Others-(21-10-2011).pdf 2011-10-21
44 3042-DELNP-2011-REQUEST FOR ADJOURNMENT OF HEARING UNDER RULE 129A [26-04-2018(online)].pdf 2018-04-26
44 3042-delnp-2011-Form-3-(21-10-2011).pdf 2011-10-21
45 3042-DELNP-2011-Response to office action (Mandatory) [06-06-2018(online)].pdf 2018-06-06
45 3042-delnp-2011-Correspondence Others-(12-10-2011).pdf 2011-10-12
46 3042-DELNP-2011-US(14)-ExtendedHearingNotice-(HearingDate-14-09-2020).pdf 2020-08-14
46 3042-delnp-2011-Form-1-(12-10-2011).pdf 2011-10-12
47 3042-DELNP-2011-Correspondence to notify the Controller [14-09-2020(online)].pdf 2020-09-14
47 3042-delnp-2011-GPA-(12-10-2011).pdf 2011-10-12

Search Strategy

1 search_06-07-2017.pdf