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Anti Glycation Composition Comprising At Least One Plant Extract And Uses Thereof

Abstract: The present disclosure composition comprising a mixture of sodium lactate and sodium gluconate, and at least one butylene glycol extract of a plant selected from the group consisting of Crithmum maritimum, Houttuynia cordata, Salacia reticulata, and combinations thereof for inhibition of glycation.

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Patent Information

Application #
Filing Date
08 September 2015
Publication Number
10/2017
Publication Type
INA
Invention Field
PHARMACEUTICALS
Status
Email
lsmds@lakshmisri.com
Parent Application

Applicants

ITC LIMITED
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India

Inventors

1. AGARWAL, Sakshi
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
2. KHAN, Manisha
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
3. HASSAN, Sarah
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
4. PHULERA, Sumit
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India

Specification

Claims:1. An anti-glycation composition comprising:
a. a mixture of sodium lactate and sodium gluconate; and
b. at least one butylene glycol extract of a plant selected from the group consisting of Crithmum maritimum, Houttuynia cordata, Salacia reticulata, and combinations thereof,
wherein sodium lactate weight concentration in said mixture is 20-25%, sodium gluconate weight concentration in said mixture is 20-25%.

2. The anti-glycation composition as claimed in claim 1, wherein said at least one butylene glycol extract of a plant is obtained from root, leaf, bark, flower, twigs, buds, seeds, wood, whole plant, and combinations thereof.

3. The anti-glycation composition as claimed in claim 1, wherein said mix weight concentration is in the range of 0.009-0.011% and Crithmum maritimum weight concentration is in the range of 0.009-0.011%.

4. The anti-glycation composition as claimed in claim 1, wherein mix weight concentration is in the range of 0.009-0.011% and Houttuynia cordata weight concentration is in the range of 0.09-0.11%; mix weight concentration is in the range of 0.0009-0.0011% and Houttuynia cordata weight concentration is in the range of 0.09-0.11%; mix weight concentration is in the range of 0.09-0.11% and Houttuynia cordata weight concentration is in the range of 0.09-0.11%; mix weight concentration is in the range of 0.0009-0.0011% and Houttuynia cordata weight concentration is in the range of 0.009-0.011%; mix weight concentration is in the range of 0.00009-0.00011% and Houttuynia cordata weight concentration is in the range of 0.009-0.011%.
5. The anti-glycation composition as claimed in claim 1, wherein mix weight concentration is in the range of 0.0009-0.0011% and Salacia reticulate weight concentration is in the range of 0.09-0.11%; mix weight concentration is in the range of 0.00009-0.00011% and Salacia reticulate weight concentration is in the range of 0.09-0.11%; mix weight concentration is in the range of 0.009-0.011% and Salacia reticulate weight concentration is in the range of 0.009-0.011%; mix weight concentration is in the range of 0.0009-0.0011% and Salacia reticulate weight concentration is in the range of 0.009-0.011%.

6. An anti-glycation formulation comprising:
a. a mixture of sodium lactate and sodium gluconate; and
b. at least one butylene glycol extract of a plant selected from the group consisting of Crithmum maritimum, Houttuynia cordata, Salacia reticulata, and combinations thereof,
wherein sodium lactate weight concentration in said mixture is 20-25%, sodium gluconate weight concentration in said mixture is 20-25%.

7. The anti-glycation formulation as claimed in claim 6, wherein Crithmum maritimum extract, Houttuynia cordata extract, and Salacia reticulata extract is obtained from root, leaf, bark, flower, twigs, buds, seeds, wood, whole plant, and combinations thereof.

8. The anti-glycation formulation as claimed in claim 6 further comprising at least one cosmetically acceptable ingredient.

9. The anti-glycation formulation as claimed in claim 8, wherein said cosmetically acceptable ingredient is selected from the group consisting of suitable carriers, diluents, skin benefitting agents, pH adjusting agents, emollients, moisturizing agent, antimicrobial agents, and excipients.
10. The anti-glycation formulation as claimed in claim 6, wherein said mix weight concentration is in the range of 0.009-0.011% and Crithmum maritimum weight concentration is in the range of 0.009-0.011%.

11. The anti-glycation formulation as claimed in claim 6, wherein mix weight concentration is in the range of 0.009-0.011% and Houttuynia cordata weight concentration is in the range of 0.09-0.11%; mix weight concentration is in the range of 0.0009-0.0011% and Houttuynia cordata weight concentration is in the range of 0.09-0.11%; mix weight concentration is in the range of 0.09-0.11% and and Houttuynia cordata weight concentration is in the range of 0.09-0.11%; mix weight concentration is in the range of 0.0009-0.0011% and Houttuynia cordata weight concentration is in the range of 0.009-0.011%; mix weight concentration is in the range of 0.00009-0.00011% and Houttuynia cordata weight concentration is in the range of 0.009-0.011%.

12. The anti-glycation formulation as claimed in claim 6, wherein mix weight concentration is in the range of 0.0009-0.0011% and Salacia reticulate weight concentration is in the range of 0.09-0.11%; mix weight concentration is in the range of 0.00009-0.00011% and Salacia reticulate weight concentration is in the range of 0.09-0.11%; mix weight concentration is in the range of 0.009-0.011% and Salacia reticulate weight concentration is in the range of 0.009-0.011%; mix weight concentration is in the range of 0.0009-0.0011% and Salacia reticulate weight concentration is in the range of 0.009-0.011%.

13. A method of preparing an anti-glycation composition as claimed in any of the claims 1-5.

14. A method of preparing an anti-glycation formulation as claimed in any of the claims 6-12.
15. An anti-glycation formulation for topical application comprising:
a. a mixture comprising sodium lactate and sodium gluconate having volume percentage in the range of 0.0001-0.1%, wherein sodium lactate weight concentration in said mixture is 20-25%, sodium gluconate weight concentration in said mixture is 20-25%;
b. at least one butylene glycol extract of a plant selected from the group consisting of Crithmum maritimum, Houttuynia cordata, Salacia reticulata, and combinations thereof, wherein Crithmum maritimum extract volume concentration is 0.01%, Houttuynia cordata extract volume concentration is in the range of 0.01-0.1%, and Salacia reticulate volume concentration is in the range of 0.01-0.1%;
c. acrylates/C10-30 alkyl acrylate cross-polymer having volume percentage of 0.07%;
d. glycerin having volume percentage of 5%;
e. butylene glycol having volume percentage of 2%;
f. D-panthenol having volume percentage of 0.5%;
g. triethanolamine having volume percentage of 0.06%;
h. mineral oil having volume percentage of 4%;
i. cetyl alcohol having volume percentage of 3%;
j. glycol distearate having volume percentage of 3%;
k. dimethicone having volume percentage of 0.5%;
l. allantoin having volume percentage of 0.1%;
m. phenoxyethanol having volume percentage of 0.3%;
n. fragrance having volume percentage of 0.2%; and
o. deionized water having volume percentage to make up 100%.

16. The anti-glycation formulation for topical application as claimed in claim 15, wherein said at least one butylene glycol extract of a plant is obtained from root, leaf, bark, flower, twigs, buds, seeds, wood, whole plant, and combinations thereof.
17. A method of preparing an anti-glycation formulation for topical application as claimed in claim 15.

18. A method for inhibiting glycation, said method comprising the steps:
a. obtaining a composition as claimed in any of the claims 1-5 or a formulation as claimed in any of the claims 6-12, and 15-16; and
b. contacting said composition or formulation with site susceptible to glycation,
wherein said method inhibits glycation.
, Description:As Attached

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