Abstract: ANTI-INFECTIVE COMPOSITION AND APPLICATIONS THEREOF The present disclosure discloses an anti-infective composition comprising a peptide 1 having an amino sequence as said forth in SEQ ID NO: 1, or derivatives thereof, U@ and a peptide 2 having an amino acid sequence as said forth in SEQ ID NO: 2, or derivatives thereof, wherein the peptide 1 has a weight percentage in a range of 0.003 to 0.0094% with respect to the composition, and the peptide 2 has a weight percentage in a range of 0.0068 to 0.025% with respect to the composition. The composition exhibits the synergistic antimicrobial efficacy against microorganisms. QP@ The present disclosure also discloses a process for preparing the composition.
1. An anti-infective composition comprising:
a) a peptide 1 having an amino sequence as said forth in SEQ ID NO: 1 or derivatives thereof; and
b) a peptide 2 having an amino acid sequence as said forth in SEQ ID NO: 2 or derivatives thereof,
wherein the peptide 1 has a weight percentage in a range of 0.003 to 0.0094% with respect to the composition, and the peptide 2 has a weight percentage in a range of 0.0068 to 0.025% with respect to the composition.
2. The anti-infective composition as claimed in claim 1, wherein the peptide 1 has a weight percentage in a range of 0.004 to 0.0085% with respect to the composition.
3. The anti-infective composition as claimed in claim 1, wherein the peptide 2 has a weight percentage in a range of 0.007 to 0.023% with respect to the composition.
4. A process for preparing the anti-infective composition as claimed in claim 1, said process comprising:
a) obtaining the peptide 1;
b) obtaining the peptide 2;
c) obtaining at least one solvent; and
d) contacting the peptide 1, the peptide 2 and the at least one solvent, to obtain the composition.
5. The process for preparing the anti-infective composition as claimed in claim 4, wherein the at least one solvent is selected from a group consisting of water, ethyl alcohol, 2-propanol, 1-propanol, and combinations thereof.
6. The process for preparing the anti-infective composition as claimed in claim 4, wherein contacting the peptide 1, the peptide 2 and the at least one solvent, at a temperature in a range of 20℃- 40℃.
7. The process for preparing the anti-infective composition as claimed in claim 4, wherein the composition has a pH in a range of 4.5 to 7.5.
8. The anti-infective composition as claimed in claim 1, wherein the
composition is effective in reducing growth of at least one type of
microorganism.
9. The anti-infective composition as claimed in claim 8, wherein the at least one
U@ type of microorganism is selected from a group consisting of bacteria, fungi,
parasites, viruses, and combinations thereof.
10. The anti-infective composition as claimed in claim 9, wherein the bacteria is
Pseudomonas aeruginosa.
11. The composition as claimed in anyone of the claims 1-3, wherein the
QP@ composition is in form of at least one substance selected from a group
consisting of antibacterial hand sanitizer, antibacterial hand wash, antibacterial wet wipes, antibacterial spray, antibacterial hand cream, antibacterial lotion, disinfectants, and antiseptics.
12. The composition as claimed in claim 1, wherein the composition further
QU@ comprises at least one excipient selected from a group consisting of aqua,
glycerine, propylene glycol, ethylhexyl glycerine, and combinations thereof.
| # | Name | Date |
|---|---|---|
| 1 | 201941021363-FORM 18 [08-05-2023(online)].pdf | 2023-05-08 |
| 1 | 201941021363-STATEMENT OF UNDERTAKING (FORM 3) [29-05-2019(online)].pdf | 2019-05-29 |
| 2 | Correspondence by Agent _Form-1,Power of Attorney_10-07-2019.pdf | 2019-07-10 |
| 2 | 201941021363-SEQUENCE LISTING(PDF) [29-05-2019(online)].pdf | 2019-05-29 |
| 3 | 201941021363-SEQUENCE LISTING [29-05-2019(online)].txt | 2019-05-29 |
| 3 | 201941021363-Proof of Right (MANDATORY) [08-07-2019(online)].pdf | 2019-07-08 |
| 4 | 201941021363-FORM-26 [03-07-2019(online)].pdf | 2019-07-03 |
| 4 | 201941021363-FORM 1 [29-05-2019(online)].pdf | 2019-05-29 |
| 5 | 201941021363-DRAWINGS [29-05-2019(online)].pdf | 2019-05-29 |
| 5 | 201941021363-Proof of Right (MANDATORY) [03-07-2019(online)].pdf | 2019-07-03 |
| 6 | 201941021363-COMPLETE SPECIFICATION [29-05-2019(online)].pdf | 2019-05-29 |
| 6 | 201941021363-DECLARATION OF INVENTORSHIP (FORM 5) [29-05-2019(online)].pdf | 2019-05-29 |
| 7 | 201941021363-COMPLETE SPECIFICATION [29-05-2019(online)].pdf | 2019-05-29 |
| 7 | 201941021363-DECLARATION OF INVENTORSHIP (FORM 5) [29-05-2019(online)].pdf | 2019-05-29 |
| 8 | 201941021363-DRAWINGS [29-05-2019(online)].pdf | 2019-05-29 |
| 8 | 201941021363-Proof of Right (MANDATORY) [03-07-2019(online)].pdf | 2019-07-03 |
| 9 | 201941021363-FORM 1 [29-05-2019(online)].pdf | 2019-05-29 |
| 9 | 201941021363-FORM-26 [03-07-2019(online)].pdf | 2019-07-03 |
| 10 | 201941021363-SEQUENCE LISTING [29-05-2019(online)].txt | 2019-05-29 |
| 10 | 201941021363-Proof of Right (MANDATORY) [08-07-2019(online)].pdf | 2019-07-08 |
| 11 | Correspondence by Agent _Form-1,Power of Attorney_10-07-2019.pdf | 2019-07-10 |
| 11 | 201941021363-SEQUENCE LISTING(PDF) [29-05-2019(online)].pdf | 2019-05-29 |
| 12 | 201941021363-STATEMENT OF UNDERTAKING (FORM 3) [29-05-2019(online)].pdf | 2019-05-29 |
| 12 | 201941021363-FORM 18 [08-05-2023(online)].pdf | 2023-05-08 |