“Anti Myostatin Antibodies”

Abstract: A neutralizing epitope is identified within amino acids 40-64 of the mature form of human myostatin. Antibodies that bind this epitope with high affinity preferentially bind GDF-8 over GDF-11 and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bone density, or for the treatment of various disorders in mammalian and avian species.

Patent Information

Application #

Filing Date

04 April 2008

Publication Number

12/2009

Publication Type

INA

Invention Field

BIOTECHNOLOGY

Status

Email

Parent Application

Patent Number

Legal Status

Grant Date

2013-12-18

Renewal Date

Applicants

ELI LILLY AND COMPANY

Lilly Corporate Center Indianapolis Indiana 46285 US

Inventors

1. HAN, Bomie

5707 Kenderly Court Carmel Indiana 46033 US

2. KORYTKO, Andrew

4720 Marblehead Bay Drive Oceanside California 92057 US

3. MITCHELL, Pamela, Jean

7168 Munsee Lane Indianapolis Indiana 46260 US

4. O’BRYAN (NEE TOBIAS), Linda

5231 Boulevard Place Indianapolis Indiana 46208 US

5. WANG, Rong

5819 Stone Pine Trail Carmel Indiana 46033 US

Specification

The invention is in the field of medicine, particularly in the field of monoclonal antibodies against myostatin. More specifically the invention relates to high affinity chmeric,...........

Documents

Orders

Section	Controller	Decision Date

Application Documents

#	Name	Date
1	2809-delnp-2008-Form-13 (08-04-2008).pdf	2008-04-08
1	2809-DELNP-2008_EXAMREPORT.pdf	2016-06-30
2	2809-delnp-2008-Claims (08-04-2008).pdf	2008-04-08
2	Form 27 [29-01-2016(online)].pdf	2016-01-29
3	ipindiaonline.gov.in_epatentfiling_online_frmPreview.asp.pdf	2015-03-20
3	2809-delnp-2008-Form-13 (26-12-2008).pdf	2008-12-26
4	Form 27.pdf	2014-04-02
4	2809-delnp-2008-Claims (26-12-2008).pdf	2008-12-26
5	2809-DELNP-2008-Form-26-(19-05-2010).pdf	2010-05-19
5	2809-delnp-2008-Claims-(28-11-2013).pdf	2013-11-28
6	2809-DELNP-2008-Correspondence-Others-(19-05-2010).pdf	2010-05-19
6	2809-delnp-2008-Correspondence Others-(28-11-2013).pdf	2013-11-28
7	Form-5.pdf	2011-08-21
7	2809-delnp-2008-Correspondence Others-(19-12-2012).pdf	2012-12-19
8	Form-3.pdf	2011-08-21
8	2809-delnp-2008-Abstract-(13-12-2012).pdf	2012-12-13
9	2809-delnp-2008-Claims-(13-12-2012).pdf	2012-12-13
9	Form-1.pdf	2011-08-21
10	2809-delnp-2008-Correspondence Others-(13-12-2012).pdf	2012-12-13
10	Drawings.pdf	2011-08-21
11	2809-delnp-2008-Form-3-(13-12-2012).pdf	2012-12-13
12	2809-delnp-2008-Correspondence Others-(13-12-2012).pdf	2012-12-13
12	Drawings.pdf	2011-08-21
13	2809-delnp-2008-Claims-(13-12-2012).pdf	2012-12-13
13	Form-1.pdf	2011-08-21
14	2809-delnp-2008-Abstract-(13-12-2012).pdf	2012-12-13
14	Form-3.pdf	2011-08-21
15	2809-delnp-2008-Correspondence Others-(19-12-2012).pdf	2012-12-19
15	Form-5.pdf	2011-08-21
16	2809-delnp-2008-Correspondence Others-(28-11-2013).pdf	2013-11-28
16	2809-DELNP-2008-Correspondence-Others-(19-05-2010).pdf	2010-05-19
17	2809-delnp-2008-Claims-(28-11-2013).pdf	2013-11-28
17	2809-DELNP-2008-Form-26-(19-05-2010).pdf	2010-05-19
18	2809-delnp-2008-Claims (26-12-2008).pdf	2008-12-26
18	Form 27.pdf	2014-04-02
19	ipindiaonline.gov.in_epatentfiling_online_frmPreview.asp.pdf	2015-03-20
19	2809-delnp-2008-Form-13 (26-12-2008).pdf	2008-12-26
20	Form 27 [29-01-2016(online)].pdf	2016-01-29
20	2809-delnp-2008-Claims (08-04-2008).pdf	2008-04-08
21	2809-DELNP-2008_EXAMREPORT.pdf	2016-06-30
21	2809-delnp-2008-Form-13 (08-04-2008).pdf	2008-04-08