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Antimicrobial Activity Of Plant Extract Against Skin Infection Causing Bacteria

Abstract: The increasing prevalence of antibiotic-resistant bacteria has driven the search for alternative antimicrobial agents from natural sources. This study evaluates the antimicrobial activity of plant extracts from mint (Mentha spica.taf neem (Azadirachta indica), rosemary (Rosmarinus officinalis), and Indian bael (Aegle marmelos) against bacteria responsible for skin infections, including Escherichia coli, Pseudomonas aeruginosa. Extracts were prepared using ethanol, methanol, and aqueous solvents and tested for antibacterial efficacy through agar well diffusion and minimum inhibitory concentration (MIC) assays. The findings revealed that all four plant extracts exhibited significant antimicrobial activity, with the ethanol extracts demonstrating the most potent effects. Mint and neem extracts showed particularly strong inhibition zones against Staphylococcus aureus and Streptococcus pyogenes. Phytochemical analysis identified the presence of bioactive compounds such as flavonoids, tannins, and terpenoids, which are likely responsible for the observed antimicrobial properties. These results suggest that extracts from mint, neem, rosemary, and Indian bael have potential as natural antimicrobial agents for the treatment of skin infections, presenting a viable alternative to conventional antibiotics. Further investigation is warranted to isolate active compounds and evaluate their clinical applicability and safety. Keywords: Bacterial skin infection, Azadirachta indica, Rosmarinus officinalis, Mentha spicata, Aegle marmelos.

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Patent Information

Application #
Filing Date
03 July 2024
Publication Number
29/2024
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
Parent Application

Applicants

VINITHA S
Sri Shakthi Institute of Engineering & Technology, Coimbatore-641062.

Inventors

1. KAVIPRIYA S
Sri Shakthi Institute of Engineering & Technology, Coimbatore-641062.
2. KISHOR R
Sri Shakthi Institute of Engineering & Technology, Coimbatore-641062.
3. PONNI M
Sri Shakthi Institute of Engineering & Technology, Coimbatore-641062.
4. VINITHA S
Sri Shakthi Institute of Engineering & Technology, Coimbatore-641062.

Specification

DESCRIPTION
Field of Invention
Antimicrobial Activity of Plant Extract Against Skin Infection Causing Bacteria" suggests a scientific study focused on evaluating the efficacy of plant-derived compounds in inhibiting or killing bacteria responsible for skin infections.
Background of the Invention
The rise of antibiotic-resistant bacteria is a global health concern, particularly in the treatment of skin infections. Traditional antibiotics are becoming less effective due to the adaptive mechanisms of bacteria, which lead to resistance. This has prompted the scientific community to seek alternative and complementary therapies to combat bacterial infections. Historically, medicinal plants have been used in various cultures for their healing properties. Many plants are known to possess natural antimicrobial compounds, such as alkaloids, flavonoids, terpenoids, and phenolic acids. These bioactive compounds can inhibit or kill a range of pathogenic microorganisms, including bacteria responsible for skin infections. This invention focuses on harnessing the antimicrobial potential of plant extracts to develop effective treatments against bacteria that cause skin infections.
Disclosure of the Invention: ’
Reference may be made to patent no: CN107648341A by Plant extracts for the treatment and prevention of infections The invention relates to a plant extract for treating and preventing infection, which discloses a composition comprising a sanguisorba officinalis plant extract and at least one additional plant extract, the additional plant extract is selected from ailanthus altissima plant extract, a Chinese gall plant extract and a light fruit and liquorice plant extract, the rheum officinale plant extract and the Scutellaria baicalensis plant extract also disclose a composition containing the ailanthus altissima extract or the ailanthus altissima extract.
Reference may be made to patent no: AU2021240472A1 by Antimicrobial solutions and methods of using the same in the treatment or prevention of infections Antimicrobial compositions include a therapeutically effective amount of neem oil, extract of the plant.
Reference may be made to patent no: US2017340691A1 by An Antimicrobial Composition The present invention provides an antimicrobial composition comprising at least one garlic extract and one or more of a bioflavonoid and/or an organic acid as well as the use of the same for treating or preventing bacterial, fungal or parasitic infections.
Reference may be made to patent no: CA2641991A1 by ANTIMICROBIAL COMPOSITIONS, METHODS AND SYSTEMS The invention provides methods for treating a surface, the method including steps of applying a surface treatment composition to a surface, wherein the surface treatment composition includes a substantially phenol-free cleansing agent and an antimicrobial agent, the antimicrobial agent comprising 9- decenoic acid, a salt of 9-decenoic acid, an ester of 9-decenoic acid, or a combination thereof, wherein the antimicrobial agent is present in an amount sufficient to control microbial growth. Also described are methods for treating a surface that include the step of applying a surface treatment composition having a pH in the range of 4.1 to 8.5 to a surface, wherein the surface treatment composition includes a cleansing agent and an antimicrobial agent, the antimicrobial agent comprising 9-decenoic acid, a salt of 9- decenoic acid, an ester of 9-decenoic acid, or a combination thereof, wherein the antimicrobial agent is present in an amount sufficient to control microbial growth. Also described are surface treatment compositions including the antimicrobial agents.
Reference may be made to patent no: KR20140099223A by ANTIMICROBIAL ' COMPOSITION USING AN PLANT EXTRACT Disclosed is an antimicrobial composition using plant extracts. More particularly, the antimicrobial composition using plant extracts contains extracts of cornelian cherry, cocculus trilobus, euscaphis japonica, or Quercus salicina Blume showing antibacterial activity against staphylococcus epidermidis and propionibacterium acnes.
CLAIMS
1. Antimicrobial activity of plant extract against skin infection causing bacteria.
2. According to claim 1, Skin infections can be caused by various types of bacteria, each with its own characteristics and implications for treatment.
3. According to claim 1, Neem (Azadirachta indica), Mint (Mentha spp.), Aegle marmelos (Bael), Rosemary (Rosmarinus officinalis) have properties such as antimicrobial, wound healing, skin soothing, cooling effects.
4. According to claim 3, These plant extracts have bioactive compounds, antioxidant
properties which serves as a effective way of treating skin infections. ,
5. According to claim 4, The raw materials are extracted and examined by Antimicrobial activities.

Documents

Application Documents

# Name Date
1 202441050942-Form 9-030724.pdf 2024-07-16
2 202441050942-Form 5-030724.pdf 2024-07-16
3 202441050942-Form 3-030724.pdf 2024-07-16
4 202441050942-Form 2(Title Page)-030724.pdf 2024-07-16
5 202441050942-Form 1-030724.pdf 2024-07-16