Abstract: The present disclosure provides an assay device and associated method(s) to facilitate the determination of risk of a subject to develop severe forms of SARS-CoV2 infection. Said determination of risk or genetic predisposition to severe forms of SARS-CoV2 infection employing the assay device and associated method(s) relies on specifically designed CRISPR-Cas system(s). Said CRISPR-Cas system(s) employed in the present disclosure are further characterized by unique guide sequences that enable detection of presence or absence of specific Single Nucleotide Polymorphisms (SNPs) in a sample, wherein the SNPs have a genetic correlation with severe forms of SARS-CoV2 infection.
| # | Name | Date |
|---|---|---|
| 1 | 202417027642-STATEMENT OF UNDERTAKING (FORM 3) [03-04-2024(online)].pdf | 2024-04-03 |
| 2 | 202417027642-PRIORITY DOCUMENTS [03-04-2024(online)].pdf | 2024-04-03 |
| 3 | 202417027642-POWER OF AUTHORITY [03-04-2024(online)].pdf | 2024-04-03 |
| 4 | 202417027642-FORM FOR SMALL ENTITY(FORM-28) [03-04-2024(online)].pdf | 2024-04-03 |
| 5 | 202417027642-FORM 18 [03-04-2024(online)].pdf | 2024-04-03 |
| 6 | 202417027642-FORM 1 [03-04-2024(online)].pdf | 2024-04-03 |
| 7 | 202417027642-FIGURE OF ABSTRACT [03-04-2024(online)].pdf | 2024-04-03 |
| 8 | 202417027642-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [03-04-2024(online)].pdf | 2024-04-03 |
| 9 | 202417027642-DRAWINGS [03-04-2024(online)].pdf | 2024-04-03 |
| 10 | 202417027642-DECLARATION OF INVENTORSHIP (FORM 5) [03-04-2024(online)].pdf | 2024-04-03 |
| 11 | 202417027642-COMPLETE SPECIFICATION [03-04-2024(online)].pdf | 2024-04-03 |
| 12 | 202417027642-RELEVANT DOCUMENTS [15-04-2024(online)].pdf | 2024-04-15 |
| 13 | 202417027642-FORM 13 [15-04-2024(online)].pdf | 2024-04-15 |
| 14 | 202417027642-AMENDED DOCUMENTS [15-04-2024(online)].pdf | 2024-04-15 |
| 15 | 202417027642-Response to office action [18-04-2024(online)].pdf | 2024-04-18 |
| 16 | 202417027642-Others-150724.pdf | 2024-07-19 |
| 17 | 202417027642-GPA-150724.pdf | 2024-07-19 |
| 18 | 202417027642-Form 28-150724.pdf | 2024-07-19 |
| 19 | 202417027642-Correspondence-150724.pdf | 2024-07-19 |
| 20 | 202417027642-FORM 3 [26-09-2024(online)].pdf | 2024-09-26 |