The present invention relates generally to the field of dispensing system. More particularly, the
invention relates to a device for dispensing medicament. It may be used for.delivering drugs in
liquid form at predetermined rates.
BACKGROUND AND THE PRIOR ART
There are a variety of pumps which dispenses very accurate amount of drugs in liquid form, but
are expensive to procure and are table1 desk top mounted. The inexpensive 'portable' varieties
that are available in the market lack accuracy and/or do not dispense the entire volume of liquid
at the same rate. Some of the prior arts in this field of invention are as follows:
US5062834 provides a device for dispensing a liquid, particularly a medicament, at a
predetermined rate, includes a container including a displaceable partition to define a first
expansible contractible chamber on one side for receiving the liquid to be dispensed, and a
second expansible-contractible chamber on the opposite side for receiving an electrolytic cell.
The electrolytic cell has electrodes and an electrolyte capable of generating, upon the
energization of the electrodes, a gas under pressure to thereby displace the displaceable partition
and to force the liquid out from the first chamber in accordance with the rate of energization of
the electrodes, a gas under pressure to thereby displace the displaceable partition and to force the
liquid out from the first chamber in accordance with the rate of energization of the electrodes.
The displaceable partition includes a piston assembly having a pair of pistons spaced apart by a
connecting stem, the container being formed with a vent opening in the space between the
pistons to prevent accidental mixing of the gas with the liquid to be dispensed.
US5090963 provides a liquid material dispenser includes a rigid housing having a flexible
partition defining first and second compartments on opposite sides of the partition, and an
electrolytic cell in the first compartment capable of generating a gas when energized by a source
of electric current in order to expand the first compartment and thereby to contract the second
compartment. The second compartment contains the liquid material which is dispensed via s
discharge opening in accordance with the rate of generation of the gas.
US5971722 provides an electrochemically driven syringe pump for infusion of medicament
wherein the pump has a detachable barrel in which medicament can be stored and subsequently
infused. The pump is further adapted for storage as the charge transfer medium is sealed in a
reservoir prior to activation.
The current product, by using an electro-mechanical drive provides accurate and consistent
dispensing and is economical to produce or procure than the available accurate dispensing
devices. The unit while achieving this remains handy and portable and could be used anywhere
as it is powered by a battery. While there are other devices that use an .electric motor to achieve
dispensing, they rely on rack and pinion, direct screw drives or belt drives to transmit the motion.
The current product uses a rotating sleeve with internal thread which pushes or pulls a screw
along its axis. The screw in turn is connected to the plunger of the syringe which contains the
liquid medicament.
The product has been developed for delivering drugs in liquid form at predetermined rates.
OBJECTS OF THE INVENTION
A basic object of the present invention is to overcome the disadvantagesldrawbacks of the known
art.
Another object of the present invention is to provide a drug dispensing device to deliver drugs in
liquid form at predetermined rates.
Another object of the present invention is to provide a drug dispensing device for generating
nano particles.
Another object of the present invention is to provide a device to dispense liquid at a
predetermined rate.
Another object of the present invention is to provide a compact hand held, self contained, syringe
driving unit.
Another object of the present invention is to provide a smooth dispensing of.the liquid such that
no turbulence is created while the "solutions" mixes with other medium,
Yet another object of the present invention is to provide a syringe that will also act as the
container for the liquid medicament.
These and other advantages of the present invention will become readily apparent from the
following detailed description read in conjunction with the accompanying drawings.
SUMMARY OF THE INVENTION
There is provided a drug dispensing device for delivering drugs in liquid form at predetermined
rates and can be used for generating nano particles.
The following presents a simplified summary of the invention in order to provide a basic
understanding of some aspects of the invention. This summary is not an extensive overview of
the present invention. It is not intended to identify the keylcritical elements of the invention or to
delineate the scope of the invention. Its sole purpose is to present some concept of the invention
in a simplified form as a prelude to a more detailed description of the invention presented later.
According to one aspect of the present invention, there is provided a device for dispensing
medicament comprising a top cover means and a bottom cover means attached through a snap
and fastener means; a syringe means for receiving and dispensing the medicament comprising a
syringe plunger having one of its ribs sandwiched between a plurality of ribs provided on the
bottom cover thereby preventing its rotary movement and allowing translator movement; a
sleeve means mounted between the top and the bottom cover means having a substantially
continuous acme threads on its inner circumference; a screw means having acme threads
carresponding to that of the sleeve means and adapted for moving subs@ntially axially along said
sleeve means; an electro-mechanical drive means powered using a power supply means activated
via a forward / reverse switch means mounted on the top cover and integrated to said sleeve
means; a control unit comprising a control PCB mounted substantially above the motor and a
switch PCB mounted substantially above the sleeve;
wherein said sleeve means rotatingly integrated to said drive means using a motor pin means
connecting a shaft of said drive means and configured to move a syringe plunger inside the
sleeve thus varying the volume of the syringe thereby drawing in or dispensing liquid
medicament;
wherein said sleeve means on activation by a reverse switch adapted for rotation in anti
clockwise direction thereby pulling back the screw thus drawing medicament from a vial, said
screw on reaching a dead end position pushing a damper plate thus activating a micro switch to
cut off power supply to the drive means; and
wherein said sleeve means on activation by a forward switch adapted for rotation in clock wise
direction thereby pushing the screw and the syringe plunger thus dispensing the medicament
therein, said screw on reaching a dead end position activating a micro switch to cut off power
supply to the drive means.
Other aspects, advantages, and salient features of the invention will become apparent to those
skilled in the art from the following detailed description, which, taken in conjunction with the
annexed drawings, discloses exemplary embodiments of the invention.
BRIEF DESCRIPTION OF THE ACCOMPANYING DRAWINGS
The following drawings are illustrative of particular examples for enabling methods of the
present invention, are descriptive of some of the methods, and are not intended to limit the scope
of the invention. The drawings are not to scale (unless so stated) and are intended for use in
conjunction with the explanations in the following detailed description.
Fig 1 shows the cross sectional view along the longitudinal axis.
Fig 2 shows the Electronic control system.
Fig 3 shows the syringe mounting slot protruding out of the sleeve.
Fig 3A shows the flange of the syringe body is securely held by the ribs'on the bottom cover.
Fig 3B shows another view of the syringe mounting slot.
Fig 3C shows the dead end position of the screw that pushes the damper plate.
Fig 4 shows the damper plate which is spring loaded.
Fig 5 shows the screw which upon reaching the fore dead end position activates another microswitch.
Persons skilled in the art will appreciate that elements in the figures are illustrated for simplicity
and clarity and may have not been drawn to scale. For example, the dimensions of some of the
elements in the figure may be exaggerated relative to other elements to help to improve
understanding of various exemplary embodiments of the present disclosure.
Throughout the drawings, it should be noted that like reference numbers are used to depict the
same or similar elements, features, and structures.
DETAILED DESCRIPTION OF THE ACCOMPANYING DRAWINGS
The following description with reference to the accompanying drawings is pr,ovided to assist in a
comprehensive understanding of exemplary embodiments of the invention as defined by the
claims and their equivalents. It includes various specific details to assist in that understanding but
these are to be regarded as merely exemplary. Accordingly, those of ordinary skill in the art will
recognize that various changes and modifications of the embodiments described herein can be
made without departing from the scope and spirit of the invention. In addition, descriptions of
well-known functions and constructions are omitted for clarity and conciseness.
The terms and words used in the following description and claims are not limited to the
bibliographical meanings, but, are merely used by the inventor to enable a clear and consistent
understanding of the invention. Accordingly, it should be apparent to those skilled in the art that
the following description of exemplary embodiments of the present invention are provided for
illustration purpose only and not for the purpose of limiting the invention as defined by the
appended claims and their equivalents.
It is to be understood that the singular forms "a," "an," and "the" include plural referents unless
the context clearly dictates otherwise.
By the term "substantially" it is meant that the recited characteristic, parameter, or value need
not be achieved exactly, but that deviations or variations, including for example, tolerances,
measurement error, measurement accuracy limitations and other factors known to those of skill
in the art, may occur in amounts that do not preclude the effect the characteristic was intended to
provide.
Accordingly the present invention provides a device for dispensing medicament. The device
comprises different components. The top cover means and bottom cover means are attached
through a snap and fastener means. There is provided a syringe means for receiving and
dispensing the medicament. This syringe means is substantially a container' containing
medicament and further comprising a syringe plunger having one of its ribs sandwiched between
a plurality of ribs provided on the bottom cover thereby preventing its rotary movement and
allowing translator movement. It also comprises a means for measuring medicament contained
therein. Syringe is configured to be inserted or removed only when the syringe plunger is in a
fully compressed position thus ensuring that the syringe is empty during handling.
Further, there is provided a sleeve means mounted between the top and the bottom cover means
having a substantially continuous acme threads on its inner circumference. A screw means
having acme threads corresponding to that of the sleeve means is provided and it is adapted for
moving substantially axially along said sleeve means.
The invention comprises an electro-mechanical drive means substantially a dc motor powered
using a power supply means activated via a forward 1 reverse switch means mounted on the top
cover and integrated to said sleeve means.
The control unit comprises a control PCB mounted substantially above the motor and a switch
PCB mounted substantially above the sleeve. Control PCB is integrated to a power switch to
prevent power leakage. Control unit further comprises a rechargeable power supply means; an
adapter means providing constant voltage source to charge the power supply means; a voltage
booster circuit providing an isolated supply for the gate drive circuitry.
The sleeve means is rotatingly integrated to said drive means using a motor pin means
connecting a shaft of said drive means and configured to move a syringe plunger inside the
sleeve thus varying the volume of the syringe thereby drawing in or dispensing liquid
medicament.
The sleeve means on activation by a reverse switch adapted for rotation in anti clockwise
direction thereby pulling back the screw thus drawing medicament from a vial, said screw on
reaching a dead end position pushing a damper plate thus activating a micro switch to cut off
power supply to the drive means.
Further said sleeve means on activation by a forward switch adapted for rotation in clock wise
direction thereby pushing the screw and the syringe plunger thus dispensing the medicament
therein, said screw on reaching a dead end position activating a micro switch to cut off power
supply to the drive means. The sleeve means is mounted to the top and bottom cover means
through a plurality of substantially self lubricating plastic bearings thereby ensuring rotation with
minimal frictional loses.
The syringe plunger adapted to move in both forward and reverse direction within approximately
4 seconds and configured to handle load torque of approximately 4 Kgcm.
Various components used in the device along with their reference numerals are detailed as
follows:
6
I
7
8
9
10
Screw
Motor1 electro
magnetic drive
means
Battery1 power
supply means
Bearing
Damper Base
1
1
1
2
1
ABS
NA
NA
STD
ABS
Dia 35,30
28*8 1
50*34*9
44* 10
35*6
The mixing device shown in the image (Fig 1) is designed to dispense a specific volume of
chemotherapeutic medicaments at a predetermined rate and the dispensing shall be consistent.
The product is designed to be hand held and runs on a battery which can be recharged through an
onboard charger by connecting to the mains.
Fig 1 shows the cross sectional view along the longitudinal axis. The product consists of the
body, which has two parts - the top cover (1) and bottom cover (2) which are attached to each
other by means of snaps and fasteners. The body houses the cylindrical sleeve (9, with internal
threads, which is connected to the electric motor (7) such that the motor rotates the sleeve while
in operation. The sleeve has a continuous ACME thread on its inner circumference running
along the length threaded onto the sleeve is a lead screw with corresponding ACME threads. The
screw is prevented from rotating with the sleeve (typically the screw gets connected with the
syringe plunger which needs to be a non-rotating part). Therefore, when the sleeve is rotated, the
screw will be driven along the thread. The direction of motion of the screw will depend on the
direction of rotation of the Sleeve. The top cover (2) has a lid (3) at fore end, which could be
opened to attach the syringe to the screw. At the aft end is the power onloff switch (14) which
cuts offlon power to the control PCB. This is provided to prevent leakage of power while the
product is not in use. The electric motor is activated via a forward 1 reverse switch (17) which is
mounted on the top cover. There are two PCBs - control PCB (12) and the switch PCB (13)
which controls the motor drive. The control PCB is mounted above the electric motor and the
switch PCB is mounted above the sleeve. The unit is powered by a rechargeable 7.4 V, 450
n~Ahb attery (8) which is mounted below the motor. The sleeve is mounted to the covers via self
lubricating plastic bearings (9) which ensure that the sleeve rotates smoothly and with minimal
frictional loses. The sleeve is connected to the shaft of the electric motor using a Motor pin (18)
which ensures sufficient flexibility between the motor and the sleeve while in operation.
The sleeve and screw arrangement in the product is reverse of what is conventionally used in
products and practical applications. In the conventional arrangement there is a core or screw
which rotates inside a sleeve which is free to move in a linearly. Such an arrangement would
require that the sleeve-screw arrangement is at substantially longer or wider than the dimensions
of the plunger thereby increasing the dimensions (length or girth) of the unit, making it difficult
for hand held operation. By reversing the roles of the screw and sleeve, it was possible to reduce
the overall dimensions and make it sufficiently compact to be a hand held unit.
The product is designed such that the syringe (16) acts as the container for the medicament. The
product is designed to be used with only one make of syringe standard 20ml syringe (make: BD
Luer Lok) with a 20 gauge 1.5 inch needle to get the optimal discharge rate.
CONTROL SYSTEM:
The Electronic control system built into the device consists of the following fbnctional blocks as
shown in Fig. 2:
Adapter
Rechargeable Li-ion Battery
Voltage Booster circuit
Control circuit
Switches and Sensors
12V DC Gear Motor
Adapter: The Adapter is an external unit that is used to charge the Li-ion battery that is used as
power source for the unit. The Adapter consists of an AC-DC converter which acts as a constant
voltage source to charge the battery.
Battery: A Rechargeable 7.4 V 450 mAh Li-ion Battery is used as power source for the unit.
Voltage Booster circuit: The Voltage Booster circuit consists of an LM3488 based boost
converter which steps up the 7.4 V battery voltage to 12V. The voltage booster circuit is meant
to provide an isolated supply for the gate drive circuitry of the H-bridge motor driver. The driver
circuitry for the H-bridge has two major purposes-
' Translate the input voltage to suitable levels to drive the gates
Provide enough current to charge and discharge the gates fast enough
Control Circuit - The control circuit consists of two parts.
An H-Bridge MOSFET based circuit controls the DC motor. The H-Bridge is an electronic
circuit which allows the voltage to be applied across the motor in either direction which allows
the motor to run forward or backward. The H-Bridge can also be used to 'brake' the motor,
which brings the motor to a sudden stop. The H-bridge is constructed using two dual N and P
channel Power MOSFETs. Protection circuits are used to protect the circuit from over current
conditions.
Battery Charge Indication circuit - A comparator based circuit is use'd to provide visual
indication to the clinician after power 'ON' regarding the battery charge status. Battery charged
condition is indicated in green and low battery condition is indicated in red. Before using the
device the user should make sure that the battery is not in the low power condition so that the
device will not shut down in the middle of a single stroke of operation.
Switches and Sensors: The device has an ONIOFF switch which disconnects the internal power
source from the rest of the operational circuits/indications/mechanisms with an electrical
resistance of 20 mega Ohms so that the battery will not drain when the device is not operational.
Indications are also provided for the forward and reverse motion of the plunger. The forward
and reverse motion of the plunger for drug dispensing and drug filling respectively fromlinto the
syringe is controlled using a switch.
In the ready to use condition the screw will be at the fore end of the sleeve with the syringe
mounting slot protruding out of the sleeve. (Fig-3) The lid is opened manually to expose the
screw which is ready to accept the empty syringe. Part of the screw which has the slot for
accepting the plunger of the syringe is exposed when the lid is opened. The design is such that a
loaded syringe cannot be inserted into the slot in the screw. This feature also acts as a safety
check preventing the user from manually handling the drug. The flange of the syringe body is
securely held by the ribs on the bottom cover as shown in fig. 3 and 3a. The lid is closed,
securing the aft end of the syringe. The syringe body is denied any degree of freedom of
movement. The syringe plunger, one of the ribs of which is sandwiched between ribs provided
on the bottom cover, is allowed translatory movement and is not allowed rotary movement. This
arrangement makes sure that the screw to which the plunger is attached is .also not allowed to
rotate.
On activating the reverse switch, the sleeve rotates in the anti clockwise direction (when viewed
from the front, facing the product) and the screw is pulled back drawing in the medicament from
the vial. Upon reaching the dead end position (fig 3C) the screw pushes the damper plate (lo),
which is spring loaded (Fig 4.) The damper, while being pushed activates a micro switch which
cuts off the power supply to the motor thereby stopping the movement. This arrangement
prevents damage to the plastic parts and also minimizes power wastage.
Once the exact amount of the medicament is drawn into the syringe, the syringe is ready to
dispense. On activating the forward switch mounted on the top cover, the sleeve is rotated by the
electric motor in the clock wise direction (when viewed from the front, facing the product). This
pushes the screw and the plunger of the syringe attached to the screw forward reducing the
volume of the syringe at a predetermined rate, thereby dispensing the medicament into the
desired medium (that cover a broad range of infusion fluids and not limited to Dextrose1
SalineIRinger lacate etc or a combination of these).
Fig 5: The screw, upon reaching the fore dead end position, activates another micro-switch,
which cuts off the power to the motor thereby stopping the motor. This prevents damage to the
plastic parts and minimizes power losses.
The syringe which is empty after dispensing the medicament is ready to be detached from the
unit. The lid at the fore end of the top cover is opened manually and the syringe is detached. The
unit does not allow removal of syringes which are not empty. This is safety feature which is built
into the unit, which prevents users from manually handling syringes while it still contains the
chemotherapeutic medicaments.
By varying the motor, battery and the gearing on the sleeve-screw. arrangement, any
predetermined rate of dispensing can be achieved using this unit.
ADVANTAGES:
Powerful device - Moves the plunger within 4 seconds and handles a load torque of 4
Kgcm.
Direction Control - Moves the plunger in both forward and reverse direction.
End point detection - When the plunger reaches the maximum in forward and reverse
directions, the end point is detected using sensor switch and further movement is not
allowed.
Battery Operated - The product operates from a single Lithium ion rechargeable battery
(7.4 V). The product does not allow operation when the battery is not enough to complete
a cycle.
Charger - The battery is charged using an external AC mains charger. Charging
indication (Red/ Green) is provided.
The sleeve is connected directly the geared motor shaft eliminating the needs for any kind of
transmission, which drastically reduces the number of moving parts. The plunger moves inside
the rotating sleeve which helps in reducing the overall length of the product. Syringe shall be
inserted through an opening provided at this area. This ensures good holding of the syringe by
the casing. This arrangement ensures that the syringe can be inserted or removed from the
product only when the plunger is in the hlly compressed position. This ensures that the syringe
is empty when it is being handled.
EXPERIMENTAL DATA:
Flow Rate Test Report D r u ~Di spenser
Timing Analysis with new 7.4V Battery for 40 Cycles:
S.NO
i
2
3
4
5
6
7
Boost OIP
Voltage
12.84
12.84
12.84
12.84
12.84
12.84
12.84
8 12.84 2.43
I 9 12.84 2.4
10 12.84 2.5 1
11 12.84 2.54
12 12.84 2.54
13 12.84 2.55
14 12.84 2.49
15 12.84 2.47
16 12.84 2.53
17 12.84 2.5
18 12.84 2.56
19 12.84 2.47
20 12.84 2.5
2 1 12.84 2.5
22 12.84 2.48
23 12.84 2.48
24 12.84 2.5 1
3.12
3.12
3.5
3.32
3.25
3.24
3.25
3.3
3.23
3.26
3.26
3.32
3.2
3.21
3.16
3.25
3.1 h
Time Measurement for 1 5ML
Intake Time (in Sec)-Electronic
2.1
2.19
2.1
2.4
2.4
2.47
2.4
(7.4Vl450mAh125C)
Dispense Time (in Sec)-Electronic
3.2
3.01
3.1
3.6
3.12
3.1
3.1
With reference to the theoretical calculation and trials taken, Consistent flow rate of 3.9 Sec
achieved @ 12.84V (Nominal voltage for driving motor) with 7.4V/450mAh/25C rechargeable
battery. After fully recharge, battery can support 33 to 35 Cycles without recharging.
The present invention can be used for a variety of applications.
It can be used for poorly water-soluble drugs or compounds. Examples of such poorly watersoluble
drugs or compounds include, but are not limited to, anticancer agents, anti-inflammatory
agents, anti-fungal agents, antiemetics, antihypertensive agents, sex hormones, steroids,
antibiotics, immunomodulators, anaesthetics etc. Typical examples of anticancer agents that can
be entrapped within the polymeric shell are Paclitaxel, Docetaxel, and other related taxane
derivatives; Irinotecan, Topotecan, and other related Camptothecin derivatives; Doxorubicin,
Daunomycin, and related Anthracycline derivatives; Cisplatin; Oxaliplatin; 5-Fluorouracil;
Mitomycin; Methotrexate; Etoposide; Betulinic acid and its derivatives; and Wedelolactone and
(Battery low indication shown after 36' cycle)
Minimum time taken for dispensing
Maximum time taken for dispensing
Average time taken for dispensing
derivatives. Typical examples of anti-inflammatory agents that can be entrapped within the
polymeric shell include Indomethacin, Ibuprofen, Ketoprofen, Flubiprofen, Piroxicam,
Tenoxicam, and Naproxen. Typical examples of anti-fbngal agents that can be entrapped within
the polymeric shell include Ketoconazole, and Amphotericin B. Typical examples of sex
hormones that can be entrapped within the polymeric shell include Testosterone, Estrogen,
Progesterone, and Estradiol. Typical examples of steroids that can be entrapped within the
polymeric shell include Dexamethasone, Prednisolone, and Triamcinolone. Typical examples of
antihypertensive agents that can be entrapped within the polymeric sheil include Captopril,
Ramipril, Terazosin, Minoxidil, and Parazosin. Typical examples of antiemetics that can be
entrapped within the polymeric shell include Ondansetron and Granisetron. Typical examples of
antibiotics that can be entrapped within the polymeric shell include Metronidazole, and Fusidic
acid. Typical examples of immunomodulators that can be entrapped within the polymeric shell
include Cyclosporine; and Biphenyl dimethyl dicarboxylic acid. Typical examples of
anaesthetics that can be entrapped within the polymeric shell include Propopol, Alfaxalone, and
Hexobarbital.
One of the various applications of the present invention is a Nanoxel Drug Dispenser. Paclitaxel
is an effective chemotherapy drug against cancer. Nanoxel is the nano particle created out of
Paclitaxel which is proprietary to Fresenius Kabi. The effectiveness of the drug improves greatly,
when administered as nano particles (of size less than 100nm). Nanoxel is administered in to
patient's body through IV system through a standard dextrose solution. Nanoxel is highly toxic
and volatile. Two solutions are required to create nano particles of Paclitaxel are:
Solution- 1 : Concentrate of Excipients for Nanoxel
Solution-2: Paclitaxel Solution for Nanoparticles.
Nanoxel Drug Dispenser in accordance with present invention can be used for mixing two
different solutions in a solution medium of dextrose, where the rate of dispensing is of utmost
importance and determines the effectiveness of the final mixture.
Nano particles of Paclitaxel are created only when these two solutions react in a medium like
dextrose solution. Nano particles of desired size is created when the mixture of the two solutions
happen at a certain flow rate and at a certain turbulence. Slower flow rate or less turbulent flow
creates lesser nano particles which are big in size, that get filtered before being administered in
to the patient's body. This significantly reduces the effectiveness of the drug. To create the nstno
particles of desired size the following procedure is adopted: At first, Solution-1 is injected in to
the pouch containing dextrose solution and shaken up thoroughly to create a homogenous
mixture. This could be done with conventional syringe and manual injection. A fresh luer lok
syringe with 20G 1.5 inch needle is inserted in to the Drug dispenser and nanoxel solution from
the vial is taken in to the syringe. This needle - as it is in the drug dispenser device - is inserted
in to the dextrose solution which also contains solution-1. The drug dispenser is a battery
operated device, with powerful mechanisms, designed to inject solution-:! at the desired flow rate
and turbulence, in to the dextrose+solution-1 mixture. The push button in the Drug dispenser is
operated to inject the Paclitaxel solution in to the Dextrose+solution-1 mixture, to create nano
particles. The pouch is examined for cloudiness of the mixture, and if found ok, ready to be
administered to the patient.
The main benefit of the present invention is that the size (Length and girth) of the device is
reduced as compared to that of the conventional arrangement. It is portable and has no
dependency on mains Power. It ensures uniform rate of flow and thus facilitates generation of
Nano particles. The moving parts are significantly eliminated thus improving the mechanical
efficiency. It may be used for filling, re-filling & dispensing.
Although the embodiments herein are described with various specific embodiments, it will be
obvious for a person skilled in the art to practice the embodiments herein with modifications.
However, all such modifications are deemed to be within the scope of the invention. It is also to
be understood that the description is intended to cover all of the generic and specific features of
the embodiments described herein and all the statements of the scope of the embodiments which
as a matter of language might be said to fall there between.

WE CLAIM:
1. A device for dispensing medicament comprising:
a top cover means and a bottom cover means attached through a snap and fastener means;
a syringe means for receiving and dispensing the medicament comprising a syringe
plunger having one of its ribs sandwiched between a plurality of ribs provided on the
bottom cover thereby preventing its rotary movement and allowing translator movement;
a sleeve means mounted between the top and the bottom cover means having a
substantially continuous acme threads on its inner circumference;
a screw means having acme threads corresponding to that of the sleeve means and
adapted for moving substantially axially along said sleeve means;
an electro-mechanical drive means powered using a power supply means activated via a
forward / reverse switch means mounted on the top cover and integrated to said sleeve
means;
a control unit comprising a control PCB mounted substantially above the motor and a
switch PCB mounted substantially above the sleeve;
wherein said sleeve means rotatingly integrated to said drive means using a motor pin
means connecting a shaft of said drive means and configured to move a syringe plunger
inside the sleeve thus varying the volume of the syringe thereby drawing in or dispensing
liquid medicament;
wherein said sleeve means on activation by a reverse switch adapted for rotation in anti
clockwise direction thereby pulling back the screw thus drawing medicament from a vial,
said screw on reaching a dead end position pushing a damper plate thus activating a
micro switch to cut off power supply to the drive means; and
wherein said sleeve means on activation by a forward switch adapted for rotation in clock
wise direction thereby pushing the screw and the syringe plunger thus dispensing the
medicament therein at a predetermined rate, said screw on reaching a dead end position
activating a micro switch to cut off power supply to the drive means.
2. Device as claimed in claim 1 wherein said electro-mechanical drive means is a motor and
adapted for driving said sleeve means.
3. Device as claimed in claim 1 wherein said syringe comprising a means for measuring
medicament contained therein.
4. Device as claimed in claim 1 wherein said syringe configured to be inserted or removed
only when the syringe plunger is in a fully compressed position thus ensuring that the
syringe is empty during handling.
5. Device as claimed in claim 1 wherein said syringe having its flange secured by a plurality
of ribs on the bottom cover.
6. Device as claimed in claim 1 wherein said control PCB is integrated to a power switch to
prevent power leakage.
7. Device as claimed in claim 1 wherein said sleeve means mounted to the top and bottom
cover means through a plurality of substantially self lubricating plastic bearings thereby
ensuring rotation with minimal frictional loses.
8. Device as claimed in claim 1 wherein said plunger adapted to move in both forward and
reverse direction within approximately 4 seconds and configured to handle load torque of
approximately 4 Kgcm.
9. Device as claimed in claim 1 wherein said control unit comprising a rechargeable power
supply means; an adapter means providing constant voltage source to charge the power
supply means; a voltage booster circuit providing an isolated supply for the gate drive

circuitry.
10. A device for dispensing medicament as herein described and illustrated with respect to
accompanying drawings.