FIELD OF THE INVENTION
The present invention relates to a novel ayurvedic formulation for curing and controlling
Diabetes mellitus and method to obtain the same.
BACKGROUND OF THE INVENTION
Diabetes mellitus refers to a group of diseases that affect how your body uses blood sugar
(glucose). Diabetes symptoms vary depending on how much your blood sugar is elevated.
Some people, especially those with pre-diabetes or type 2 diabetes, may not experience
symptoms initially. In type 1 diabetes, symptoms tend to come on quickly and be more
severe.
As of 2017, an estimated 425 million people had diabetes worldwide, with type 2 diabetes
making up about 90% of the cases. This represents 8.8% of the adult population, with
equal rates in both women and men. Trend suggests that rates will continue to
rise. Diabetes at least doubles a person's risk of early death.
In order to survive Diabetes mellitus generally people are prescribed medications that used
to treat diabetes do so by lowering blood sugar levels. There is broad consensus that when
people with diabetes maintain tight glucose control (also called "tight glycemic control") –
keeping the glucose levels in their blood within normal ranges – that they experience
fewer complications like kidney problems and eye problems. There is however debate as
to whether this is cost effective for people later in life. There are a number of different
classes of anti-diabetic medications. Some are available by mouth, such as metformin,
while others are only available by injection such as GLP-1 agonists. Type- 1 diabetes can
only be treated with insulin, typically with a combination of regular and NPH insulin, or
synthetic insulin analogs both the methods are expensive, exhaustive and are largely
unaffordable to common people. Hence, there exists a need for an alternative method or
medication that allows the patients to combat with such chronic diseases.
Researches have demonstrated that herbal and ayurvedic medicines and treatments also
support reinstatement of Insulin as required.
Prior arts namely IN 201911017624 titled as Vitamin and Mineral Composition for the
Treatment of Type 2 Diabetes and Method Thereof discloses an oral, mineral and vitamin
formulation consisting of Vitamin D3, Vitamin K2-7 and Magnesium Salt of Orotic Acid
in synergistic ratios for the prevention and treatment of Type 2 diabetes. The composition
when taken orally at a specific optimal dose of 2100 mg (700 mg after each meal i.e. 3
times a day) for about 3-6 months, results in significant glycemic control.
Further, IN 201821029783 titled as A Herbal Composition For Treatment Of Type- 2
Diabetes discloses A herbal composition for the treatment of type 2 diabetes comprising
whole fruit of Phyllanthus emblica whole fruit of Momordica charantia, whole fruit of
Syzygium cumini, and roots of Plumbago zeylanica in the range of 7-10% w/w in dry
powdered form, whole plant of Swertia Chirayita excluding roots in the range of 3-5%
w/w in dry powdered form, whole fruit of Terminalia chebula in the range of 11.5-13.5%
w/w in dry powdered form, leaves of Aegle Marmelos in the range of 11.5-13.5% w/w in
dry powdered form , whole fruit of Carum roxburghianum in the range of 7-10% w/w in
dry powdered form, whole plant of Tribulus terrestris excluding roots in the range of 7-
10% w/w in dry powdered form , whole plant of Picrorhiza Kurroa, excluding roots in the
range of 7-10% w/w in dry powdered form, whole plant of Cassia angustifolia excluding
roots in the range of 7-10% w/w in dry powdered form and, salt in the range of 3.5- 6.5%,
w/w in the dry powdered form is disclosed.
Also, IN 201811008460 titled as Natural Formulation for Type-2 Diabetes discloses and
ayurvedic herbo-mineral formulation for treating type-2 diabetes by clearing excess of
lipids from peripheral human body cells. The formulation contains 105 ingredients.
The current invention, herbal formulation has its roots in Ayurveda-ancient herbal
healthcare system of India. The disclosed formula is packed with natural herbs and helps
avoiding the disease naturally. This herbal composition is an effective alternative remedy
for diabetes which has proven good efficacy, less constituents, provides cost effective
measure and have no side effects.
SUMMARY OF INVENTION
The present invention has been developed in response to the present state of the art, and in
particular, in response to the problems and needs in the art that have not yet been fully
solved by currently available techniques and processes. Accordingly, the present invention
has been developed to provide an effective herbal formulation for curing Diabetes
mellitus.
As it is known that causes of pre-diabetes and type 2 diabetes, In pre-diabetes — which
can lead to type 2 diabetes — and in type 2 diabetes, your cells become resistant to the
action of insulin, and your pancreas is unable to make enough insulin to overcome this
resistance. Instead of moving into your cells where it's needed for energy, sugar builds up
in your bloodstream. The current invention reverses this scenario and helps controlling the
said disease.
Therefore, the main objective of the present invention is to provide an effective ayurvedic
formulation essentially comprised of constituents namely Prunus amygdalus, Aegle
marmelos, Emblica officinalis, Ocimum Sanctum, Swertis Chirata, Vitis vinifera,
Momordica Charantia and Piper Longum.
The afore mentioned ingredients have digestive, appetising, rejuvenative, bio enhancing
properties along with being antibiotic as well as bactericidal and have specific properties
that enhances the efficacy of the constituents.
The above constituents are taken in specific proportions and in their preferable forms that
are listed in Table 1 and Table 2 respectively.
In preferred embodiment all ingredients are mixed with water (filtered water) n kept it for
6 to 8 hour. Then same mixture is boiled for 2-3 hour for temperature about 150C, and
same boiled mixture is allowed to cool. The mixture is rolled in spinning machine for
extracting the liquid. In the extracted liquid some preservatives chemicals are added n kept
it for 6-7 hour. After this the medicine is ready for packing in bottle.
Treating Diabetes mellitus, herbal composition of the present invention provides a
composition, and a pharmaceutically acceptable carrier which can be easily prepared in a
variety of dosage forms, To facilitate administration of clinical and experimental results,
the present invention provides compositions which are effective and reliable, the use of it
safe, non-toxic side effects of long-term use.
OBJECTS OF THE INVENTION:
It is the main object of the invention to provide a novel herbal formulation for treatment of
Diabetes mellitus that is not only curative but is also a prophylactic solution.
Further it is also an object of the present invention to provide a medication that is cost
effective and affordable to large group of people.
It is further an object of the present invention to provide a process of production of
Ayurvedic formulation.
The present invention is not only effective in the treatment of diabetes but is also effective
in the prevention of the same. The treatment of diabetes disclosed herein is non-toxic,
without side effects, easy to use and low priced.
Other objects and advantages of the invention will become apparent as the foregoing
description proceeds, taken together with the accompanying drawings and the appended
claims.
BRIEF DESCRIPTION OF ACCOMPANYING DRAWINGS
In order to describe the manner in which the above-recited and other advantages and
features of the invention can be obtained, a more particular description of the invention
briefly described above will be rendered by reference to specific embodiments thereof,
which are illustrated in the appended drawings. And that the elements of similar structure
or function are generally represented by reference numerals for illustrative purposes
throughout the figures. Understanding that these drawings depict only typical
embodiments of the invention and are not therefore to be considered to be limiting of its
scope, the invention will be described and explained with additional specificity and detail
through the use of the accompanying drawings in which:
Fig. 1 illustrates the Schematic diagram of the process obtaining the disclosed formulation.
DEFINITIONS:
DECOCTION: a concentrated liquor resulting from heating or boiling a substance,
especially a medicinal preparation made from a plant.
Svarasa - The juice of the plant, which is the strongest of all, is extracted by pounding or
grinding it in a blender.
Kalka - The herbs are crushed and made into a pulp form in the required consistency by
adding sufficient water.
Kvatha - It is prepared by boiling the herbs in water until the preparation is reduced to
one-fourth of the original amount.
DETAILED DESCRIPTION OF THE EMBODIMENTS
This invention disclosure describes the subject matter for patenting with specificity to
meet statutory requirements. However, the description itself is not intended to limit the
scope of this patent. The principles described herein may be embodied in many different
forms.
Illustrative embodiments of the invention now will be described more fully hereinafter
with reference to the accompanying drawings, in which some, but not all embodiments of
the invention are shown. Indeed, the invention may be embodied in many different forms
and should not be construed as limited to the embodiments set forth herein; rather, these
embodiments are provided so that this disclosure will satisfy applicable legal
requirements. Like numbers refer to like elements throughout.
The present invention discloses a comprised of a method and formulation for curing the
Diabetes mellitus, wherein the formulation is essentially comprised of ayurvedic and
herbal constituents. The formulation is essentially comprised of Prunus amygdalus, Aegle
marmelos, Emblica officinalis, Ocimum Sanctum, Swertis Chirata, Vitis vinifera,
Momordica Charantia and Piper Longum along with other excipients and constituents.
Each of the listed constituents and their form is carefully selected because of their unique
properties and compatibility with selected group of constituents.
In the preferred embodiment, the current invention formulation essentially comprises of
primary constituents in measures as mentioned in Table-1 listed below:
Table – 1-Primary Constituents
Composition of Formulation
Component Quantity(In percentage)-for 100 ml
Prunus amygdalus 3.5
Aegle marmelos 5.0
Emblica officinalis 3.0
Ocimum Sanctum 2.5
And Form and Part of constituent used are listed in Table-2 below:
All of the aforementioned constituents have digestive, appetizing, rejuvenative, bioenhancing
properties along with being antibiotic as well as bactericidal.
The current invention may be used in any form, as topical gel, capsule, tablet etc.
In preferred embodiment the excipients such as Carbopol, TEA and water as base is taken.
Method of Preparation:
All ingredients are mixed with water (filtered water) n kept it for 6 to 8 hour. Then same
mixture is boiled for 2-3 hour for temperature about 150C, and same boiled mixture is
allowed to cool. The mixture is rolled in spinning machine for extracting the liquid.
In the extracted liquid some preservatives chemicals are added n kept it for 6-7 hour. After
this the medicine is ready for packing in bottle.
In further description a method of obtaining the current invention herbal composition, will
be explained in detail.
Process: The final product is obtained by following a systematic process of mixing,
boiling, churning and addition of preservatives.
Swertis Chirata 3.0
Vitis vinifera 2.5
Momordica Charantia 1.5
Piper Longum 3.0
Table-2
Component Part Used Form
Prunus amygdalus Seeds Extract
Aegle marmelos Leaf Extract
Emblica officinalis Root Extract
Ocimum Sanctum All parts Extract
Swertis Chirata Whole plant Extract
Vitis vinifera Fruit Extract
Momordica Charantia Fruit Extract
Piper Longum Fruit Extract
Selection and quantification: Accurately weighted components of constituents
mentioned in Table- 1 and 2 are taken separately and in their requisite forms.
Mixing: The constituents as mentioned in Table 1 are weighed and are mixed together in
water till completion of 6-8 hours.
The submerged mixture is 2-3 hour for temperature about 150C and thereafter cooled at
room temperature.
The cooled mixture is then churned well in a spinning machine till the extract is obtained.
Addition of excipients and Preservatives: The final mixture is preferably used as it is for
use; however natural preservatives; additives and excipients may also be added in
permissible limits. In preferred embodiment sodium Benzoate is used as preservative.
The Shelf life of the disclosed formulation is 2 years from date of manufacture.
Process Parameters:
A. Temperature: The temperature range of about 130 degree to 150 degrees, most
preferably 150 degree Celsius is used for preparing the decoction.
B. Aeration: Aerobic condition is required for the mentioned process.
C. Agitation: non-continuous mixing is required.
Diagnostic Parameters:
Diabetes mellitus is characterized by recurrent or persistent high blood sugar, and is
diagnosed by demonstrating any one of the following:
Fasting plasma glucose level ≥ 7.0 mmol/l (126 mg/dl)
Plasma glucose ≥ 11.1 mmol/l (200 mg/dl) two hours after a 75 gram oral glucose load as
in a glucose tolerance test (OGTT)
Symptoms of high blood sugar and casual plasma glucose ≥ 11.1 mmol/l (200 mg/dl)
Glycated hemoglobin (HbA1C) ≥ 48 mmol/mol (≥ 6.5 DCCT %).[67]
A positive result, in the absence of unequivocal high blood sugar, should be confirmed by
a repeat of any of the above methods on a different day. It is preferable to measure a
fasting glucose level because of the ease of measurement and the considerable time
commitment of formal glucose tolerance testing, which takes two hours to complete and
offers no prognostic advantage over the fasting test. According to the current definition,
two fasting glucose measurements above 7.0 mmol/l (126 mg/dl) is considered diagnostic
for diabetes mellitus.
Diagnostic criteria:
1 Sample 100 Individual with Diabetes mellitus selected.
2 Inclusive Criteria 1. Age group 13-80yrs, clinically diagnosed with
diabetes
3 Exclusive Criteria 1. Pregnant Females.
2. People with allergies
4 Method Formulation is administered topically in gel form
5 Materials used All constituents listed in formulation
6 Assessment Criteria Improvement in Insulin level.
7 Duration 4 weeks-6 weeks.
8 Comparison All Groups are compared
Analysis of results: It has been observed that 98% positives results clinically and no sideeffects
are reported.
The present invention is treatment of Diabetes mellitus with traditional Indian medicinal
and herbal composition, the respective raw materials, pharmaceutically acceptable carrier
and an extract can be prepared as granules, tablets, capsules, oral liquid, or mixture pellets.
When the present invention is made into a tablet, carrier as lactose or corn starch,
magnesium stearate lubricants are added when required, mixed well, and then tableted.
When the present invention is made in capsules, the powder is filled in required doses in
the capsule shells to form capsules.
When the present invention is made into granules, the herbal extracts extract plus dextrin
are mixed uniformly, granulated and dried to prepare a granule.
Since other modifications and changes varied to fit particular operating requirements and
environments are apparent to those skilled in the art, the invention is not considered
limited to the example chosen for purposes of disclosure, and covers all changes and
modifications which do not constitute departures from the true spirit and scope of this
invention.
This written description uses examples to disclose the invention, including the best mode,
and also to enable any person skilled in the art to practice the invention, including making
and using any devices or systems and performing any incorporated methods. The above
are merely exemplary and illustrative of the inventive concept by, one of ordinary skill in
the art in the specific embodiments described to make various modifications or additions,
or a similar alternative manner, without departing from the invention. The invention, as
defined in this disclosure or beyond the scope of the claims, should belong to the scope of
the present invention.

I, CLAIM:
1. An ayurvedic formulation essentially comprised of Prunus amygdalus, Aegle
marmelos, Emblica officinalis, Ocimum Sanctum, Swertis Chirata, Vitis vinifera,
Momordica Charantia and Piper Longum
2. The ayurvedic formulation as claimed in claim 1 wherein the constituents Prunus
amygdalus is 3.5 percent, Aegle marmelos is 5.0 percent, Emblica officinalis is 3.0
percent, Ocimum Sanctum is 2.5 percent, Swertis Chirata is 3.0 percent, Vitis
vinifera is 2.5 percent, Momordica Charantia is 1.5 percent and Piper Longum is
3.0 percent in an 100 ml solution.
3. The ayurvedic formulation as claimed in claim 1 wherein the constituents Prunus
amygdalus is in seed form, Aegle marmelos is taken as leaves, Emblica officinalis
roots is taken, Ocimum Sanctum and Swertis Chirata are used as whole, Vitis
vinifera , Momordica Charantia and Piper Longum in form of fruit.
4. The ayurvedic formulation as claimed in claim 1, wherein the constituents are
weighed and are mixed together in their requisite forms in water till completion of
6-8 hours, thereafter the mixture is boiled and later cooled to room temperature.
5. The ayurvedic formulation as claimed in claim 1, wherein the temperature range of
about 120 degree to 150 degrees, most preferably 150 degree Celsius is used for
preparing the decoction.
6. The ayurvedic formulation as claimed in claim 1, wherein the final mixture is
preferably used as it is for use; however natural preservatives; additives and
excipients may also be added in permissible limits, preferably sodium Benzoate is
used as preservative.
7. The ayurvedic formulation as claimed in claim 1, wherein the Shelf life of the
disclosed formulation is 2 years from date of manufacture.