Sign In to Follow Application
View All Documents & Correspondence
View All Documents & Correspondence
Bicyclic Heterocyclic Compound
Abstract: [Problem] To provide a compound useful as the active ingredient in a drug composition for treating diseases to which 11ß hydroxysteroid dehydrogenase type 1 contributes such as dementia schizophrenia depression pain (particularly neuropathic pain and fibromyalgia) diabetes (particularly type 2 diabetes) and insulin resistance. [Solution] It was discovered that a bicyclic heterocyclic compound substituted with an acylamino group such as a (hetero)aroylamino group (the bicyclic heterocycle being formed by condensing a cyclohexane ring and a 5 or 6 membered monocyclic heterocycle having only a nitrogen atom as the heteroatom) or a pharmaceutically acceptable salt thereof has a superior selective inhibitory action with respect to 11ß HSD1. Thus the bicyclic heterocyclic compound can be used in the treatment of dementia schizophrenia depression pain (particularly neuropathic pain and fibromyalgia) diabetes (particularly type 2 diabetes) insulin resistance and the like
Get Free WhatsApp Updates!
Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
17 April 2014
Publication Number
27/2015
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
patent@depenning.com
Parent Application
Patent Number
Legal Status
Grant Date
2019-08-27
Renewal Date
Applicants
ASTELLAS PHARMA INC.
5 1 Nihonbashi Honcho 2 chome Chuo ku Tokyo
1038411
Inventors
1. KAWAKAMI Shimpei
c/o Astellas Pharma Inc. 3 11 Nihonbashi Honcho 2 chome Chuo ku Tokyo
1038411
2. SAKURAI Minoru
c/o Astellas Research Technologies Co. Ltd. 21 Miyukigaoka Tsukuba shi Ibaraki
3058585
3. KAWANO Noriyuki
c/o Astellas Research Technologies Co. Ltd. 21 Miyukigaoka Tsukuba shi Ibaraki
3058585
4. SUZUKI Takayuki
c/o Astellas Pharma Inc. 3 11 Nihonbashi Honcho 2 chome Chuo ku Tokyo
1038411
5. SHIRAISHI Nobuyuki
c/o Astellas Pharma Inc. 3 11 Nihonbashi Honcho 2 chome Chuo ku Tokyo
1038411
6. HAMAGUCHI Wataru
c/o Astellas Pharma Inc. 3 11 Nihonbashi Honcho 2 chome Chuo ku Tokyo
1038411
7. SEKIOKA Ryuichi
c/o Astellas Pharma Inc. 3 11 Nihonbashi Honcho 2 chome Chuo ku Tokyo
1038411
8. MORITOMO Hiroyuki
c/o Astellas Pharma Inc. 3 11 Nihonbashi Honcho 2 chome Chuo ku Tokyo
1038411
9. MORITOMO Ayako
c/o Astellas Pharma Inc. 3 11 Nihonbashi Honcho 2 chome Chuo ku Tokyo
1038411
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | Form 2_As Filed_17-04-2014.pdf | 2014-04-17 |
| 2 | English Translation_As Filed_17-04-2014.pdf | 2014-04-17 |
| 3 | Description Complete_As Filed_17-04-2014.pdf | 2014-04-17 |
| 4 | Claims_As Filed_17-04-2014.pdf | 2014-04-17 |
| 5 | Abstract_As Filed_17-04-2014.pdf | 2014-04-17 |
| 6 | Astellas Pharma Inc.pdf | 2014-04-21 |
| 7 | 2949-CHENP-2014.pdf | 2014-04-21 |
| 8 | 1406-2014.pdf | 2014-04-21 |
| 9 | 1406-2014 OTHERS.pdf | 2014-04-21 |
| 10 | 1406 form 5.pdf | 2014-04-21 |
| 11 | 1406 form 3.pdf | 2014-04-21 |
| 12 | 2949-CHENP-2014 POWER OF ATTORNEY 02-06-2014.pdf | 2014-06-02 |
| 13 | 2949-CHENP-2014 CORRESPONDENCE OTHERS 02-06-2014.pdf | 2014-06-02 |
| 14 | 2949-CHENP-2014 FORM-3 15-10-2014.pdf | 2014-10-15 |
| 15 | 2949-CHENP-2014 CORRESPONDENCE OTHERS 15-10-2014.pdf | 2014-10-15 |
| 16 | Marked Copy [15-10-2015(online)].pdf | 2015-10-15 |
| 17 | Form 13 [15-10-2015(online)].pdf | 2015-10-15 |
| 18 | Description(Complete) [15-10-2015(online)].pdf | 2015-10-15 |
| 19 | 2949-CHENP-2014 FORM-13 15-10-2015.pdf | 2015-10-15 |
| 20 | 2949-CHENP-2014-Other Patent Document-151015.pdf | 2016-03-16 |
| 21 | 2949-CHENP-2014-FORM 3 [09-08-2017(online)].pdf | 2017-08-09 |
| 22 | 2949-CHENP-2014-FER.pdf | 2018-06-13 |
| 23 | 2949-CHENP-2014-certified copy of translation (MANDATORY) [12-07-2018(online)].pdf | 2018-07-12 |
| 24 | 2949-CHENP-2014-PETITION UNDER RULE 137 [22-11-2018(online)].pdf | 2018-11-22 |
| 25 | 2949-CHENP-2014-Proof of Right (MANDATORY) [26-11-2018(online)].pdf | 2018-11-26 |
| 26 | 2949-CHENP-2014-OTHERS [26-11-2018(online)].pdf | 2018-11-26 |
| 27 | 2949-CHENP-2014-Information under section 8(2) (MANDATORY) [26-11-2018(online)].pdf | 2018-11-26 |
| 28 | 2949-CHENP-2014-FORM-26 [26-11-2018(online)].pdf | 2018-11-26 |
| 29 | 2949-CHENP-2014-FER_SER_REPLY [26-11-2018(online)].pdf | 2018-11-26 |
| 30 | 2949-CHENP-2014-CLAIMS [26-11-2018(online)].pdf | 2018-11-26 |
| 31 | 2949-CHENP-2014-certified copy of translation (MANDATORY) [26-11-2018(online)].pdf | 2018-11-26 |
| 32 | 2949-CHENP-2014-ABSTRACT [26-11-2018(online)].pdf | 2018-11-26 |
| 33 | Correspondence by Agent_Proof Of Right_05-12-2018.pdf | 2018-12-05 |
| 34 | 2949-CHENP-2014-HearingNoticeLetter.pdf | 2019-03-29 |
| 35 | 2949-CHENP-2014-REQUEST FOR ADJOURNMENT OF HEARING UNDER RULE 129A [22-04-2019(online)].pdf | 2019-04-22 |
| 36 | 2949-CHENP-2014-FORM 3 [27-05-2019(online)].pdf | 2019-05-27 |
| 37 | 2949-CHENP-2014-Correspondence to notify the Controller (Mandatory) [18-07-2019(online)].pdf | 2019-07-18 |
| 38 | 2949-CHENP-2014-ExtendedHearingNoticeLetter_24-07-2019.pdf | 2019-07-24 |
| 39 | 2949-CHENP-2014-Written submissions and relevant documents (MANDATORY) [07-08-2019(online)].pdf | 2019-08-07 |
| 40 | 2949-CHENP-2014-Retyped Pages under Rule 14(1) (MANDATORY) [07-08-2019(online)].pdf | 2019-08-07 |
| 41 | 2949-CHENP-2014-PETITION UNDER RULE 137 [07-08-2019(online)].pdf | 2019-08-07 |
| 42 | 2949-CHENP-2014-PETITION UNDER RULE 137 [07-08-2019(online)]-1.pdf | 2019-08-07 |
| 43 | 2949-CHENP-2014-MARKED COPY [07-08-2019(online)].pdf | 2019-08-07 |
| 44 | 2949-CHENP-2014-Information under section 8(2) (MANDATORY) [07-08-2019(online)].pdf | 2019-08-07 |
| 45 | 2949-CHENP-2014-CORRECTED PAGES [07-08-2019(online)].pdf | 2019-08-07 |
| 46 | 2949-CHENP-2014-certified copy of translation (MANDATORY) [07-08-2019(online)].pdf | 2019-08-07 |
| 47 | 2949-CHENP-2014-Annexure (Optional) [07-08-2019(online)].pdf | 2019-08-07 |
| 48 | 2949-CHENP-2014-2. Marked Copy under Rule 14(2) (MANDATORY) [07-08-2019(online)].pdf | 2019-08-07 |
| 49 | Marked up Claims_Granted 319095_27-08-2019.pdf | 2019-08-27 |
| 50 | Description_Granted 319095_27-08-2019.pdf | 2019-08-27 |
| 51 | Claims_Granted 319095_27-08-2019.pdf | 2019-08-27 |
| 52 | Abstract_Granted 319095_27-08-2019.pdf | 2019-08-27 |
| 53 | 2949-CHENP-2014-PatentCertificate27-08-2019.pdf | 2019-08-27 |
| 54 | 2949-CHENP-2014-IntimationOfGrant27-08-2019.pdf | 2019-08-27 |
| 55 | 2949-CHENP-2014-RELEVANT DOCUMENTS [04-03-2020(online)].pdf | 2020-03-04 |
Search Strategy
| 1 | searchstrategy2949chenp2014(1)_11-06-2018.pdf |
| 2 | availabledocuments2949chenp2014_11-06-2018.pdf |