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"Bile Acids And Biguanides As Protease Inhibitors For Preserving The Integrity Of Peptides In The Gut"

Abstract: This invention relates to methods of preserving the integrity of peptides in the gut. In particular it concerns the use of certain compounds as inhibitors of gut proteases. Compounds identified as having gut protease inhibitory activity are biguanides, certain bile acids and pharmaceutically acceptable salts of these compounds. This activity makes these compounds useful for co-administration with prophylactic or therapeutic peptides. This invention relates to methods of inhibiting gut proteases and peptide formulations comprising these gut protease inhibitor.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
01 April 2011
Publication Number
13/2012
Publication Type
INA
Invention Field
PHARMACEUTICALS
Status
Email
sna@sna-ip.com
Parent Application
Patent Number
Legal Status
Grant Date
2025-10-31
Renewal Date

Applicants

AXCESS LIMITED
CHARTER PLACE, 23/75 SEATON PLACE, ST. HELIER, JERSEY JE1 1JY, UNITED KINGDOM

Inventors

1. NEW, ROGER, R., C.
THE LONDON BIOSCIENCE INNOVATION CENTRE, 2 ROYAL COLLEGE STREET, LONDA NW1 0NH, UNITED KINGDOM
2. TRAVERS, GLEN
THE LONDON BIOSCIENCE INNOVATION CENTRE, 2 ROYAL COLLEGE STREET, LONDA NW1 0NH, UNITED KINGDOM

Specification

Documents

Orders

Section Controller Decision Date
SECTION 15 SUBENDU KUNDU 2020-04-27
Section 117A SUBENDU KUNDU 2025-10-31

Application Documents

# Name Date
1 2427-delnp-2011-GPA-(12-09-2011).pdf 2011-09-12
2 2427-delnp-2011-Form-3-(12-09-2011).pdf 2011-09-12
3 2427-delnp-2011-Correspondence-Others-(12-09-2011).pdf 2011-09-12
4 2427-delnp-2011-GPA-(21-10-2011).pdf 2011-10-21
5 2427-delnp-2011-Correspondence Others-(21-10-2011).pdf 2011-10-21
6 2427-delnp-2011-Correspondence Others-(02-11-2011).pdf 2011-11-02
7 Abstract.jpg 2011-12-02
8 2427-delnp-2011-Form-5.pdf 2011-12-02
9 2427-delnp-2011-Form-3.pdf 2011-12-02
10 2427-delnp-2011-Form-2.pdf 2011-12-02
11 2427-delnp-2011-Form-1.pdf 2011-12-02
12 2427-delnp-2011-Drawings.pdf 2011-12-02
13 2427-delnp-2011-Description (Complete).pdf 2011-12-02
14 2427-delnp-2011-Correspondence-others.pdf 2011-12-02
15 2427-delnp-2011-Claims.pdf 2011-12-02
16 2427-delnp-2011-Abstract.pdf 2011-12-02
17 2427-delnp-2011-Form-3-(17-02-2012).pdf 2012-02-17
18 2427-delnp-2011-Correspondence-Others-(17-02-2012).pdf 2012-02-17
19 2427-delnp-2011-Form-18-(21-08-2012).pdf 2012-08-21
20 2427-delnp-2011-Correspondence-Others-(21-08-2012).pdf 2012-08-21
21 2427-delnp-2011-Form-3-(30-12-2015).pdf 2015-12-30
22 2427-delnp-2011-Correspondence Others-(30-12-2015).pdf 2015-12-30
23 2427-DELNP-2011-FER.pdf 2017-04-11
24 PROOF OF RIGHT [06-07-2017(online)].pdf 2017-07-06
25 Certified Copy of Priority Document [06-07-2017(online)].pdf 2017-07-06
26 2427-DELNP-2011-OTHERS-100717.pdf 2017-07-14
27 2427-DELNP-2011-Correspondence-100717.pdf 2017-07-14
28 2427-DELNP-2011-FORM 4(ii) [12-09-2017(online)].pdf 2017-09-12
29 2427-DELNP-2011-RELEVANT DOCUMENTS [18-12-2017(online)].pdf 2017-12-18
30 2427-DELNP-2011-PETITION UNDER RULE 137 [18-12-2017(online)].pdf 2017-12-18
31 2427-DELNP-2011-OTHERS [18-12-2017(online)].pdf 2017-12-18
32 2427-DELNP-2011-FORM 3 [18-12-2017(online)].pdf 2017-12-18
33 2427-DELNP-2011-FER_SER_REPLY [18-12-2017(online)].pdf 2017-12-18
34 2427-DELNP-2011-DRAWING [18-12-2017(online)].pdf 2017-12-18
35 2427-DELNP-2011-COMPLETE SPECIFICATION [18-12-2017(online)].pdf 2017-12-18
36 2427-DELNP-2011-CLAIMS [18-12-2017(online)].pdf 2017-12-18
37 2427-DELNP-2011-ABSTRACT [18-12-2017(online)].pdf 2017-12-18
38 2427-DELNP-2011-Proof of Right (MANDATORY) [02-01-2018(online)].pdf 2018-01-02
39 2427-DELNP-2011-RELEVANT DOCUMENTS [03-01-2018(online)].pdf 2018-01-03
40 2427-DELNP-2011-PETITION UNDER RULE 137 [03-01-2018(online)].pdf 2018-01-03
41 2427-DELNP-2011-FER_SER_REPLY [09-01-2018(online)].pdf 2018-01-09
42 2427-DELNP-2011-OTHERS-050118.pdf 2018-01-10
43 2427-DELNP-2011-Correspondence-050118.pdf 2018-01-10
44 2427-DELNP-2011-Proof of Right (MANDATORY) [06-02-2018(online)].pdf 2018-02-06
45 2427-DELNP-2011-OTHERS-090218.pdf 2018-02-15
46 2427-DELNP-2011-Correspondence-090218.pdf 2018-02-15
47 2427-DELNP-2011-HearingNoticeLetter.pdf 2018-02-28
48 2427-DELNP-2011-REQUEST FOR ADJOURNMENT OF HEARING UNDER RULE 129A [12-03-2018(online)].pdf 2018-03-12
49 2427-DELNP-2011-Written submissions and relevant documents (MANDATORY) [20-04-2018(online)].pdf 2018-04-20
50 2427-DELNP-2011-Written submissions and relevant documents (MANDATORY) [20-04-2018(online)]-1.pdf 2018-04-20
51 2427-DELNP-2011-Response to office action (Mandatory) [23-08-2018(online)].pdf 2018-08-23
52 2427-DELNP-2011-REQUEST FOR CERTIFIED COPY [21-07-2020(online)].pdf 2020-07-21
53 2427-DELNP-2011-REQUEST FOR CERTIFIED COPY [21-07-2020(online)]-1.pdf 2020-07-21
54 2427-DELNP-2011-Miscellaneous-HearingNotice-(HearingDate-28-07-2025).pdf 2025-07-14
55 2427-DELNP-2011-REQUEST FOR ADJOURNMENT OF HEARING UNDER RULE 129A [24-07-2025(online)].pdf 2025-07-24
56 2427-DELNP-2011-Miscellaneous-ExtendedHearingNotice-(HearingDate-27-08-2025)-1130.pdf 2025-07-28
57 2427-DELNP-2011-REQUEST FOR ADJOURNMENT OF HEARING UNDER RULE 129A [22-08-2025(online)].pdf 2025-08-22
58 2427-DELNP-2011-Miscellaneous-ExtendedHearingNotice-(HearingDate-08-09-2025)-1600.pdf 2025-08-25
59 2427-DELNP-2011-Correspondence to notify the Controller [04-09-2025(online)].pdf 2025-09-04
60 2427-DELNP-2011-Miscellaneous-ExtendedHearingNotice-(HearingDate-10-09-2025)-1500.pdf 2025-09-05
61 2427-DELNP-2011-Correspondence to notify the Controller [09-09-2025(online)].pdf 2025-09-09
62 2427-DELNP-2011-Response to office action [25-09-2025(online)].pdf 2025-09-25
63 2427-DELNP-2011-RELEVANT DOCUMENTS [25-09-2025(online)].pdf 2025-09-25
64 2427-DELNP-2011-MARKED COPIES OF AMENDEMENTS [25-09-2025(online)].pdf 2025-09-25
65 2427-DELNP-2011-FORM 13 [25-09-2025(online)].pdf 2025-09-25
66 2427-DELNP-2011-AMMENDED DOCUMENTS [25-09-2025(online)].pdf 2025-09-25
67 2427-DELNP-2011-PatentCertificate31-10-2025.pdf 2025-10-31
68 2427-DELNP-2011-IntimationOfGrant31-10-2025.pdf 2025-10-31
69 2427-DELNP-2011-Others-071125.pdf 2025-11-13
70 2427-DELNP-2011-Correspondance-071125.pdf 2025-11-13

Search Strategy

1 SearchStrategy_05-04-2017.pdf

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