Abstract: The present disclosure discloses a xeno-free bio-ink formulation amenable to be printed using a 3D printer. The bio-ink formulation exhibits optimum viscosity in the range of 1690-5300 cP. The present disclosure discloses a bio-printed corneal lenticule obtained from the bio-ink formulation. The bio-printed corneal lenticule as disclosed is of the optimum thickness in the range of 10-500 microns and exhibits transmittance in the range of 80-99%. The present disclosure also discloses a process for preparing the bio-ink formulation as well as for preparing the bio-printed corneal lenticule. Further, the present disclosure discloses a method of treating a corneal defect using the bio-printed corneal lenticule as an implant to treat the corneal defect. The bio-printed corneal lenticule can further be used as a model for in-vitro drug testing and diseases modelling.
| # | Name | Date |
|---|---|---|
| 1 | 202247006743.pdf | 2022-02-08 |
| 2 | 202247006743-STATEMENT OF UNDERTAKING (FORM 3) [08-02-2022(online)].pdf | 2022-02-08 |
| 3 | 202247006743-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [08-02-2022(online)].pdf | 2022-02-08 |
| 4 | 202247006743-FORM 1 [08-02-2022(online)].pdf | 2022-02-08 |
| 5 | 202247006743-DRAWINGS [08-02-2022(online)].pdf | 2022-02-08 |
| 6 | 202247006743-DECLARATION OF INVENTORSHIP (FORM 5) [08-02-2022(online)].pdf | 2022-02-08 |
| 7 | 202247006743-COMPLETE SPECIFICATION [08-02-2022(online)].pdf | 2022-02-08 |
| 8 | 202247006743-FORM-26 [15-03-2022(online)].pdf | 2022-03-15 |
| 9 | 202247006743-Proof of Right [07-07-2022(online)].pdf | 2022-07-07 |
| 10 | 202247006743-FORM 3 [04-08-2022(online)].pdf | 2022-08-04 |
| 11 | 202247006743-FORM 3 [10-02-2023(online)].pdf | 2023-02-10 |
| 12 | 202247006743-FORM 18 [19-07-2023(online)].pdf | 2023-07-19 |
| 13 | 202247006743-FORM 3 [08-08-2023(online)].pdf | 2023-08-08 |
| 14 | 202247006743-FER.pdf | 2025-05-16 |
| 15 | 202247006743-FORM 3 [23-06-2025(online)].pdf | 2025-06-23 |
| 16 | 202247006743-FORM 4 [05-11-2025(online)].pdf | 2025-11-05 |
| 1 | 202247006743_SearchStrategyNew_E_SearchHistoryE_15-05-2025.pdf |