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Biomarkers, Kits Including The Biomarkers And Methods For Identifying Multiple Sclerosis Using The Same
Abstract: An in-vitro method, composition and kit for detecting biomarkers indicative of predicting and/or managing multiple sclerosis (MS) in patients either at CIS stage or early stage or thereafter stages of multiple sclerosis using clinically isolated syndrome cerebrospinal fluid (CIS-CSF), multiple sclerosis cerebrospinal fluid and reactive proteins.The cerebrospinal fluid (CSF) sample is first obtained from the patients and biotinylated. The biotin conjugated components contained in CSF is further contacted with a protein reagent sample set including Protein DJ1 (PDJ1), PHB, Actin-Cyt, Annex-A3, STL2, HSP71, PEBP, APoA1, SAP and FBAC. Detecting a measurable change in the binding property with the binding agents bound to the biotinylated CSF sample’s is indicative of MS in the subject.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
23 November 2019
Publication Number
22/2021
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
ipo@knspartners.com
Parent Application
Applicants
AMRITA VISHWA VIDYAPEETHAM
AIMS Campus, Amrita Lane
AIMS Ponekkara P.O, Kochi, Kerala
India
Inventors
1. MENON, Krishnakumar N.
Amrita Vishwa Vidyapeetham
Centre for Nanosciences & Molecular Medicine AIMS Ponekkara P.O, Kochi, Kerala India – 682041
2. NAIR, Sreepriya
Amrita Vishwa Vidyapeetham
Centre for Nanosciences & Molecular Medicine AIMS Ponekkara P.O, Kochi, Kerala India – 682041
3. MADATHIPARAMBIL, Satheesh Kumaran
Amrita Vishwa Vidyapeetham
Centre for Nanosciences & Molecular Medicine AIMS Ponekkara P.O, Kochi, Kerala India – 682041
Specification
DESC: To be attached ,CLAIMS: To be attached
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 201941020538-FORM 18 [09-12-2021(online)].pdf | 2021-12-09 |
| 1 | 201941020538-STATEMENT OF UNDERTAKING (FORM 3) [23-05-2019(online)].pdf | 2019-05-23 |
| 2 | 201941020538-EDUCATIONAL INSTITUTION(S) [08-12-2021(online)].pdf | 2021-12-08 |
| 2 | 201941020538-PROVISIONAL SPECIFICATION [23-05-2019(online)].pdf | 2019-05-23 |
| 3 | 201941020538-POWER OF AUTHORITY [23-05-2019(online)].pdf | 2019-05-23 |
| 3 | 201941020538-FORM 13 [25-08-2021(online)].pdf | 2021-08-25 |
| 4 | 201941020538-POA [25-08-2021(online)].pdf | 2021-08-25 |
| 4 | 201941020538-FORM 1 [23-05-2019(online)].pdf | 2019-05-23 |
| 5 | 201941020538-RELEVANT DOCUMENTS [25-08-2021(online)].pdf | 2021-08-25 |
| 5 | 201941020538-Proof of Right (MANDATORY) [06-12-2019(online)].pdf | 2019-12-06 |
| 6 | Correspondence by Agent_Form1_11-12-2019.pdf | 2019-12-11 |
| 6 | 201941020538-Form1_After Filing_31-03-2021.pdf | 2021-03-31 |
| 7 | 201941020538-Proof of Right [30-03-2021(online)].pdf | 2021-03-30 |
| 7 | 201941020538-PostDating-(05-10-2020)-(E-6-229-2020-CHE).pdf | 2020-10-05 |
| 8 | 201941020538-COMPLETE SPECIFICATION [23-11-2020(online)].pdf | 2020-11-23 |
| 8 | 201941020538-APPLICATIONFORPOSTDATING [05-10-2020(online)].pdf | 2020-10-05 |
| 9 | 201941020538-CORRESPONDENCE-OTHERS [23-11-2020(online)].pdf | 2020-11-23 |
| 9 | 201941020538-DRAWING [23-11-2020(online)].pdf | 2020-11-23 |
| 10 | 201941020538-CORRESPONDENCE-OTHERS [23-11-2020(online)].pdf | 2020-11-23 |
| 10 | 201941020538-DRAWING [23-11-2020(online)].pdf | 2020-11-23 |
| 11 | 201941020538-APPLICATIONFORPOSTDATING [05-10-2020(online)].pdf | 2020-10-05 |
| 11 | 201941020538-COMPLETE SPECIFICATION [23-11-2020(online)].pdf | 2020-11-23 |
| 12 | 201941020538-PostDating-(05-10-2020)-(E-6-229-2020-CHE).pdf | 2020-10-05 |
| 12 | 201941020538-Proof of Right [30-03-2021(online)].pdf | 2021-03-30 |
| 13 | 201941020538-Form1_After Filing_31-03-2021.pdf | 2021-03-31 |
| 13 | Correspondence by Agent_Form1_11-12-2019.pdf | 2019-12-11 |
| 14 | 201941020538-Proof of Right (MANDATORY) [06-12-2019(online)].pdf | 2019-12-06 |
| 14 | 201941020538-RELEVANT DOCUMENTS [25-08-2021(online)].pdf | 2021-08-25 |
| 15 | 201941020538-FORM 1 [23-05-2019(online)].pdf | 2019-05-23 |
| 15 | 201941020538-POA [25-08-2021(online)].pdf | 2021-08-25 |
| 16 | 201941020538-FORM 13 [25-08-2021(online)].pdf | 2021-08-25 |
| 16 | 201941020538-POWER OF AUTHORITY [23-05-2019(online)].pdf | 2019-05-23 |
| 17 | 201941020538-EDUCATIONAL INSTITUTION(S) [08-12-2021(online)].pdf | 2021-12-08 |
| 17 | 201941020538-PROVISIONAL SPECIFICATION [23-05-2019(online)].pdf | 2019-05-23 |
| 18 | 201941020538-STATEMENT OF UNDERTAKING (FORM 3) [23-05-2019(online)].pdf | 2019-05-23 |
| 18 | 201941020538-FORM 18 [09-12-2021(online)].pdf | 2021-12-09 |
| 19 | 201941020538-FER.pdf | 2025-07-14 |
| 20 | 201941020538-FORM 3 [08-09-2025(online)].pdf | 2025-09-08 |
| 21 | 201941020538-FORM-26 [13-11-2025(online)].pdf | 2025-11-13 |
Search Strategy
| 1 | 201941020538_SearchStrategyNew_E_Searchstrategy_msE_14-07-2025.pdf |