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Block Copolymer Having Phenylboronic Acid Group Introduced Therein And Use Thereof

Abstract: The present invention provides a block copolymer which can act as a carrier that can achieve both the stability of a biotechnology based drug in blood and the release of the biotechnology based drug at an affected area. The block copolymer according to the present invention comprises a polyamino acid chain segment and a hydrophilic polymer chain segment wherein the polyamino acid chain segment contains an amino acid residue having a cationic group in a side chain thereof and an amino acid residue having a phenylboronic acid group in a side chain thereof wherein at least one hydrogen atom in a phenyl ring in the phenylboronic acid group is substituted so that the resultant block copolymer can have a pKa value close to the physiological pH value.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
13 May 2014
Publication Number
41/2015
Publication Type
INA
Invention Field
POLYMER TECHNOLOGY
Status
Email
patent@depenning.com
Parent Application

Applicants

THE UNIVERSITY OF TOKYO
3 1 Hongo 7 chome Bunkyo ku Tokyo 1138654
NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
5 45 Yushima 1 chome Bunkyo ku Tokyo 1138510
NANOCARRIER CO. LTD.
5 4 19 Kashiwanoha Kashiwa shi Chiba 2770882

Inventors

1. KATAOKA Kazunori
c/o The University of Tokyo 3 1 Hongo 7 chome Bunkyo ku Tokyo 1138654
2. ISHII Takehiko
c/o The University of Tokyo 3 1 Hongo 7 chome Bunkyo ku Tokyo 1138654
3. NAITO Mitsuru
c/o The University of Tokyo 3 1 Hongo 7 chome Bunkyo ku Tokyo 1138654
4. MATSUMOTO Akira
c/o National University Corporation Tokyo Medical and Dental University 5 45 Yushima 1 chome Bunkyo ku Tokyo 1138510
5. KATO Yasuki
c/o NanoCarrier Co. Ltd. 5 4 19 Kashiwanoha Kashiwa shi Chiba 2270882

Specification

Documents

Application Documents

# Name Date
1 SPECIFICATION.pdf 2014-05-13
2 SEQUENCE LISTING.txt 2014-05-13
3 Form 5.pdf 2014-05-13
4 Form 3.pdf 2014-05-13
5 1703-2014 OTHERS.pdf 2014-05-13
6 3580-CHENP-2014.pdf 2014-07-10
7 3580-CHENP-2014 POWER OF ATTORNEY 12-09-2014.pdf 2014-09-12
8 3580-CHENP-2014 FORM-3 12-09-2014.pdf 2014-09-12
9 3580-CHENP-2014 FORM-1 12-09-2014.pdf 2014-09-12
10 3580-CHENP-2014 CORRESPONDENCE OTHERS 12-09-2014.pdf 2014-09-12
11 3580-CHENP-2014 FORM-13 25-09-2014.pdf 2014-09-25
12 3580-CHENP-2014 FORM-13 26-09-2014.pdf 2014-09-26
13 3580-CHENP-2014 - FORM13.pdf 2014-09-26
14 KATO.pdf 2014-09-29
15 3580-CHENP-2014-Form 3-290915.pdf 2015-11-30
16 3580-CHENP-2014-Correspondence-290915.pdf 2015-11-30
17 3580-CHENP-2014-Correspondence-161015.pdf 2016-03-22
18 Form 3 [17-06-2016(online)].pdf 2016-06-17
19 Form 3 [04-07-2016(online)].pdf 2016-07-04
20 Form 3 [08-07-2016(online)].pdf 2016-07-08
21 Form 3 [28-12-2016(online)].pdf 2016-12-28
22 Form 3 [27-02-2017(online)].pdf 2017-02-27
23 3580-CHENP-2014-FER.pdf 2019-05-31
24 3580-CHENP-2014-AbandonedLetter.pdf 2019-12-03

Search Strategy

1 2019-05-3110-14-55_31-05-2019.pdf