Abstract: The present invention provides a block copolymer which can act as a carrier that can achieve both the stability of a biotechnology based drug in blood and the release of the biotechnology based drug at an affected area. The block copolymer according to the present invention comprises a polyamino acid chain segment and a hydrophilic polymer chain segment wherein the polyamino acid chain segment contains an amino acid residue having a cationic group in a side chain thereof and an amino acid residue having a phenylboronic acid group in a side chain thereof wherein at least one hydrogen atom in a phenyl ring in the phenylboronic acid group is substituted so that the resultant block copolymer can have a pKa value close to the physiological pH value.
| # | Name | Date |
|---|---|---|
| 1 | SPECIFICATION.pdf | 2014-05-13 |
| 2 | SEQUENCE LISTING.txt | 2014-05-13 |
| 3 | Form 5.pdf | 2014-05-13 |
| 4 | Form 3.pdf | 2014-05-13 |
| 5 | 1703-2014 OTHERS.pdf | 2014-05-13 |
| 6 | 3580-CHENP-2014.pdf | 2014-07-10 |
| 7 | 3580-CHENP-2014 POWER OF ATTORNEY 12-09-2014.pdf | 2014-09-12 |
| 8 | 3580-CHENP-2014 FORM-3 12-09-2014.pdf | 2014-09-12 |
| 9 | 3580-CHENP-2014 FORM-1 12-09-2014.pdf | 2014-09-12 |
| 10 | 3580-CHENP-2014 CORRESPONDENCE OTHERS 12-09-2014.pdf | 2014-09-12 |
| 11 | 3580-CHENP-2014 FORM-13 25-09-2014.pdf | 2014-09-25 |
| 12 | 3580-CHENP-2014 FORM-13 26-09-2014.pdf | 2014-09-26 |
| 13 | 3580-CHENP-2014 - FORM13.pdf | 2014-09-26 |
| 14 | KATO.pdf | 2014-09-29 |
| 15 | 3580-CHENP-2014-Form 3-290915.pdf | 2015-11-30 |
| 16 | 3580-CHENP-2014-Correspondence-290915.pdf | 2015-11-30 |
| 17 | 3580-CHENP-2014-Correspondence-161015.pdf | 2016-03-22 |
| 18 | Form 3 [17-06-2016(online)].pdf | 2016-06-17 |
| 19 | Form 3 [04-07-2016(online)].pdf | 2016-07-04 |
| 20 | Form 3 [08-07-2016(online)].pdf | 2016-07-08 |
| 21 | Form 3 [28-12-2016(online)].pdf | 2016-12-28 |
| 22 | Form 3 [27-02-2017(online)].pdf | 2017-02-27 |
| 23 | 3580-CHENP-2014-FER.pdf | 2019-05-31 |
| 24 | 3580-CHENP-2014-AbandonedLetter.pdf | 2019-12-03 |
| 1 | 2019-05-3110-14-55_31-05-2019.pdf |