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Carboxy Substituted Glucocorticoid Receptor Agonists

Abstract: The present invention provides a compound of Formula I: (I) wherein R1 is H, halogen, C1-C3 alkyl, or C1-C3 alkoxy; R2 is H or halogen; and X is O, OCH2, or CH2, or a pharmaceutically acceptable salt thereof, wherein the compound of Formula I, or pharmaceutically acceptable salt thereof is useful for treating autoimmune and inflammatory diseases, such as atopic dermatitis, rheumatoid arthritis, and lupus nephritis.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
23 August 2023
Publication Number
49/2023
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

ELI LILLY AND COMPANY
LILLY CORPORATE CENTER Indianapolis, Indiana 46285

Inventors

1. STITES, Ryan Edward
c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288
2. WURST, Jacqueline Mary
c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, Indiana 46206-6288

Specification

Documents

Application Documents

# Name Date
1 202317056457-STATEMENT OF UNDERTAKING (FORM 3) [23-08-2023(online)].pdf 2023-08-23
2 202317056457-REQUEST FOR EXAMINATION (FORM-18) [23-08-2023(online)].pdf 2023-08-23
3 202317056457-POWER OF AUTHORITY [23-08-2023(online)].pdf 2023-08-23
4 202317056457-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [23-08-2023(online)].pdf 2023-08-23
5 202317056457-FORM 18 [23-08-2023(online)].pdf 2023-08-23
6 202317056457-FORM 1 [23-08-2023(online)].pdf 2023-08-23
7 202317056457-DECLARATION OF INVENTORSHIP (FORM 5) [23-08-2023(online)].pdf 2023-08-23
8 202317056457-COMPLETE SPECIFICATION [23-08-2023(online)].pdf 2023-08-23
9 202317056457-CLAIMS UNDER RULE 1 (PROVISIO) OF RULE 20 [23-08-2023(online)].pdf 2023-08-23
10 202317056457-Proof of Right [19-09-2023(online)].pdf 2023-09-19
11 202317056457-FORM 3 [06-02-2024(online)].pdf 2024-02-06
12 202317056457-FER.pdf 2025-05-05
13 202317056457-FORM-26 [13-06-2025(online)].pdf 2025-06-13
14 202317056457-FORM 3 [13-06-2025(online)].pdf 2025-06-13

Search Strategy

1 202317056457_SearchStrategyNew_E_SearchHistoryE_28-04-2025.pdf