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Combination Therapy Involving Antibodies Against Claudin 18.2 And Immune Checkpoint Inhibitors For Treatment Of Cancer

Abstract: The present invention provides a combination therapy comprising an anti-Claudin (CLDN) 18.2 antibody and an immune checkpoint inhibitor for effectively treating and/or preventing diseases associated with cells expressing CLDN18.2, including cancer diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder and metastases thereof.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
02 February 2022
Publication Number
10/2022
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
patent@depenning.com
Parent Application

Applicants

ASTELLAS PHARMA INC.
5-1, Nihonbashi-Honcho 2-chome, Chuo-ku, Tokyo 1038411

Inventors

1. YAMADA, Tomohiro
c/o Astellas Pharma Inc., 5-1, Nihonbashi-Honcho 2-chome, Chuo-ku, Tokyo 1038411

Specification

Documents

Application Documents

# Name Date
1 202247005588.pdf 2022-02-02
2 202247005588-STATEMENT OF UNDERTAKING (FORM 3) [02-02-2022(online)].pdf 2022-02-02
3 202247005588-SEQUENCE LISTING(PDF) [02-02-2022(online)].pdf 2022-02-02
4 202247005588-SEQUENCE LISTING [02-02-2022(online)].txt 2022-02-02
5 202247005588-PROOF OF RIGHT [02-02-2022(online)].pdf 2022-02-02
6 202247005588-PRIORITY DOCUMENTS [02-02-2022(online)].pdf 2022-02-02
7 202247005588-FORM 1 [02-02-2022(online)].pdf 2022-02-02
8 202247005588-DRAWINGS [02-02-2022(online)].pdf 2022-02-02
9 202247005588-DECLARATION OF INVENTORSHIP (FORM 5) [02-02-2022(online)].pdf 2022-02-02
10 202247005588-COMPLETE SPECIFICATION [02-02-2022(online)].pdf 2022-02-02
11 202247005588-FORM-26 [25-04-2022(online)].pdf 2022-04-25
12 202247005588-FORM 3 [14-07-2022(online)].pdf 2022-07-14
13 202247005588-Correspondence_Form1_GPA_20-10-2022.pdf 2022-10-20
14 202247005588-FORM 3 [23-01-2023(online)].pdf 2023-01-23
15 202247005588-FORM 3 [26-07-2023(online)].pdf 2023-07-26
16 202247005588-FORM 18 [26-07-2023(online)].pdf 2023-07-26
17 202247005588-FORM 3 [11-01-2024(online)].pdf 2024-01-11