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Composition Comprising Andrographis Paniculata Extract, And Vitis Vinifera L. Extract, And Uses Thereof

Abstract: The present disclosure provides a composition comprising Andrographis paniculata extract, and Vitis vinifera L. extract, obtained from various plant parts, which at particular w/w ratios is particularly useful in reduction of intracellular cholesterol levels. This finds potential application in nature based medicaments and lifestyle enhancing edible products for better health.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
11 February 2016
Publication Number
33/2017
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
lsmds@lakshmisri.com
Parent Application

Applicants

ITC LIMITED
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3. 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India

Inventors

1. KUDTARKAR, Kavita Gopalkrishna
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India
2. SHETTY, Shilpa
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India
3. KS, Nandakumar
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India
4. RADHAKRISHNAN, Yashwanth
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India
5. CHITTUR, Lakshmanan Chandrasekharan
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India

Specification

Claims:1. A composition comprising:
a. Andrographis paniculata extract; and
b. Vitis vinifera L. extract,
wherein Andrographis paniculata extract to Vitis vinifera L. extract w/w ratio is in the range of 1:0.16-1:1.

2. The composition as claimed in claim 1, wherein Andrographis paniculata extract to Vitis vinifera L. extract w/w ratio is 1:0.37.

3. The composition as claimed in claim 1, wherein Andrographis paniculata extract weight concentration in said composition is in the range of 0.00025-0.00075%, and Vitis vinifera L. extract weight concentration in said composition is in the range of 0.000125-0.00025%.

4. The composition as claimed in claim 2, wherein Andrographis paniculata extract weight concentration in said composition is 0.0005%, and Vitis vinifera L. extract weight concentration in said composition is 0.000187%.

5. The composition as claimed in claim 1, wherein said Andrographis paniculata extract is obtained from stems and leaves; said Vitis vinifera L. extract is obtained from seeds.

6. The composition as claimed in any of the claims 1-5, further comprising suitable carriers, diluents, and excipients.

7. A method of preparing a composition as claimed in any of the claims 1-6.

8. A method of inhibiting intracellular cholesterol levels, said method comprising:
a. obtaining a composition as claimed in any of the claims 1-6; and
b. contacting said composition with cells comprising cholesterol,
wherein said method inhibits intracellular cholesterol levels.

9. A composition as claimed in any of the claims 1-6 for use in preparing oral formulations for inhibition of intracellular cholesterol.
, Description:As Attached

Documents

Orders

Section Controller Decision Date

Application Documents

# Name Date
1 Form 5 [11-02-2016(online)].pdf 2016-02-11
2 Form 3 [11-02-2016(online)].pdf 2016-02-11
3 Drawing [11-02-2016(online)].pdf 2016-02-11
4 Description(Complete) [11-02-2016(online)].pdf 2016-02-11
5 201641004921-Power of Attorney-110416.pdf 2016-06-30
6 201641004921-Form 1-110416.pdf 2016-06-30
7 201641004921-Correspondence-Form 1-PA-110416.pdf 2016-06-30
8 201641004921-FORM 18 [07-01-2020(online)].pdf 2020-01-07
9 201641004921-FER.pdf 2022-04-25
10 201641004921-FER_SER_REPLY [21-10-2022(online)].pdf 2022-10-21
11 201641004921-CLAIMS [21-10-2022(online)].pdf 2022-10-21
12 201641004921-US(14)-HearingNotice-(HearingDate-30-01-2024).pdf 2023-12-26
13 201641004921-Correspondence to notify the Controller [25-01-2024(online)].pdf 2024-01-25
14 201641004921-FORM-26 [30-01-2024(online)].pdf 2024-01-30
15 201641004921-Written submissions and relevant documents [13-02-2024(online)].pdf 2024-02-13
16 201641004921-Response to office action [23-07-2024(online)].pdf 2024-07-23

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