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Composition Comprising Dipeptide And Calcium Salt, And Process Of Preparation Thereof

Abstract: COMPOSITION COMPRISING DIPEPTIDE AND CALCIUM SALT, AND PROCESS OF PREPARATION THEREOF The present disclosure provides compositions comprising at least one calcium salt and a dipeptide, which when used in combination with a w/w ratio range of 6:1 to 64.55:1, is effective in increasing the bioavailability of calcium and promotes bone growth. The present disclosure further provides a convenient process for preparing the composition.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
17 October 2018
Publication Number
16/2020
Publication Type
INA
Invention Field
BIO-CHEMISTRY
Status
Email
iprdel@lakshmisri.com
Parent Application

Applicants

ITC LIMITED
ITC Life Sciences & Technology Centre 3, 1st Main Road, Peenya Industrial Area, Phase 1, Bengaluru, Karnataka 560058, India.

Inventors

1. DSOUZA, Avin
Life Sciences and Technology Centre, ITC Limited, #3, 1st Main, Peenya Industrial Area, Phase I, Bangalore 560058, India.
2. MIRIYALA, Amarnath
Life Sciences and Technology Centre, ITC Limited, #3, 1st Main, Peenya Industrial Area, Phase I, Bangalore 560 058, India.
3. NARAYANAPER UMAL, Jeyaparthasarathy
Life Sciences and Technology Centre, ITC Limited, #3, 1st Main, Peenya Industrial Area, Phase I, Bangalore 560 058, India.
4. SHIVAPPA, Raghu Hirisave
Life Sciences and Technology Centre, ITC Limited, #3, 1st Main, Peenya Industrial Area, Phase I, Bangalore 560 058, India.
5. GOPAL, Ganesh
Life Sciences and Technology Centre, ITC Limited, #3, 1st Main, Peenya Industrial Area, Phase I, Bangalore 560 058, India.

Specification

1. A composition comprising:
a) at least one calcium salt; and
b) a dipeptide composed of leucine and cysteine,
wherein the calcium salt to the dipeptide w/w ratio is in a range of 6:1 to 64.55:1.
2. The composition as claimed in claim 1, wherein the at least one calcium salt to the dipeptide has a w/w ratio in the range of 10:1 to 17:1
3. The composition as claimed in claim 1, wherein the at least one calcium salt to the dipeptide has a w/w ratio in the range of 16:1 to 17:1
4. The composition as claimed in any one of the claims 1- 3 comprising:

a) at least one calcium salt having a concentration in a range of 443.92 µg/ml u 887.84 µg/ml with respect to the composition; and
b) dipeptide having a concentration in a range of 25 u 100 µg/ml with respect to the composition.

5. The composition as claimed in any one of the claims 1 - 4, wherein the at least one calcium salt is selected from a group consisting of calcium chloride, calcium carbonate, calcium gluconate, calcium lactate, calcium phosphate, calcium glycerophosphate, calcium hydroxide, and combinations thereof.
6. The composition as claimed in any one of the claims 1- 5, wherein the composition further comprises at least one excipient selected from a group consisting of fillers, preservatives, coloring agent, flavoring agent, emulsifier, carriers,#and combinations thereof, and wherein the at least one excipient having a weight percentage in the range of 50 u 60% with respect to the composition.
7. The composition as claimed in any one of the claims 1-6, wherein the composition synergistically upregulates absorption of calcium.
8. The composition as claimed in any one of the claims 1-7, wherein the composition is dispensed in the form of a dietary supplement selected from a group consisting of powdered beverage mix, nutrition bar, dairy products, juices, capsule, health drink, bakery and confectionary products.

9. A process for preparing the composition as claimed in claim 1, said process
comprising:
a) obtaining the at least one calcium salt;
b) obtaining the dipeptide; and
c) contacting the calcium salt with the dipeptide, to obtain the composition.
10. A process for preparing the composition as claimed in claim 6, said process
comprising:
a) obtaining the at least one calcium salt;
b) obtaining the dipeptide;
c) obtaining the at least one excipient; and
d) contacting the at least one calcium salt and the dipeptide, with the at least one excipient, to obtain the composition.

Documents

Application Documents

# Name Date
1 201841039463-STATEMENT OF UNDERTAKING (FORM 3) [17-10-2018(online)].pdf 2018-10-17
2 201841039463-FORM 1 [17-10-2018(online)].pdf 2018-10-17
3 201841039463-DRAWINGS [17-10-2018(online)].pdf 2018-10-17
4 201841039463-DECLARATION OF INVENTORSHIP (FORM 5) [17-10-2018(online)].pdf 2018-10-17
5 201841039463-COMPLETE SPECIFICATION [17-10-2018(online)].pdf 2018-10-17
6 201841039463-Proof of Right (MANDATORY) [28-11-2018(online)].pdf 2018-11-28
7 201841039463-FORM-26 [28-11-2018(online)].pdf 2018-11-28
8 Correspondence by Agent_Form1_Power of Attorney_29-11-2018.pdf 2018-11-29
9 201841039463-FORM 18 [12-10-2022(online)].pdf 2022-10-12
10 201841039463-FER.pdf 2025-11-18

Search Strategy

1 201841039463_SearchStrategyNew_E_SearchStrategyAPPN-3-Ca-dipepE_18-11-2025.pdf