Abstract: The present disclosure provides compositions comprising plant extracts, which in particular w/w ratios, and weight concentrations exhibits enhanced epithelial wound closure. Also provided are methods of preparing said compositions and uses.
Claims:1. A composition comprising:
a. Pyrus malus fruit extract; and
b. at least one extract selected from the group consisting of:
i. Schizandra chinensis fruit extract;
ii. Callendulla officinalis flower extract;
iii. Ficus carica fruit extract;
iv. Nymphaea alba flower extract; and
v. combinations thereof,
wherein Pyrus malus fruit extract to at least one extract w/w ratio is in the range of 1:0.033-1:30.
2. The composition as claimed in claim 1, wherein Pyrus malus fruit extract weight concentration in said composition is in the range of 50-150 ppm, and at least one extract weight concentration in said composition is in the range of 5-1500 ppm.
3. The composition as claimed in claim 1, wherein Pyrus malus fruit extract to Schizandra chinensis fruit extract w/w ratio in said composition is in the range of 1:3.33-1:30.
4. The composition as claimed in claim 3, wherein Pyrus malus fruit extract weight concentration in said composition is in the range of 50-150 ppm, and Schizandra chinensis fruit extract weight concentration in said composition is in the range of 500-1500 ppm.
5. The composition as claimed in claim 1, wherein Pyrus malus fruit extract to Callendulla officinalis flower extract w/w ratio in said composition is in the range of 1:0.33-1:3.
6. The composition as claimed in claim 5, wherein Pyrus malus fruit extract weight concentration in said composition is in the range of 50-150 ppm, and Callendulla officinalis flower extract weight concentration in said composition is in the range of 50-150 ppm.
7. The composition as claimed in claim 1, wherein Pyrus malus fruit extract to Ficus carica fruit extract w/w ratio in said composition is in the range of 1:0.033-1:0.3.
8. The composition as claimed in claim 7, wherein Pyrus malus fruit extract weight concentration in said composition is in the range of 50-150 ppm, and Ficus carica fruit extract weight concentration in said composition is in the range of 5-15 ppm.
9. The composition as claimed in claim 1, wherein Pyrus malus fruit extract to Nymphaea alba flower extract w/w ratio in said composition is in the range of 1:0.33-1:3.
10. The composition as claimed in claim 9, wherein Pyrus malus fruit extract weight concentration in said composition is in the range of 50-150 ppm, and Nymphaea alba flower extract weight concentration in said composition is in the range of 50-150 ppm.
11. The composition as claimed in any of the claims 1-10 further comprising suitable carriers, diluents, and excipients.
12. A method of preparing a composition as claimed in any of the claims 1-11.
13. A method of epidermal wound closure, said method comprising:
a. obtaining a composition as claimed in any of the claims 1-11; and
b. contacting said composition with site of epidermal wound,
wherein said method promotes epidermal wound closure.
, Description:As Attached
| # | Name | Date |
|---|---|---|
| 1 | Form 5 [24-02-2016(online)].pdf | 2016-02-24 |
| 2 | Form 3 [24-02-2016(online)].pdf | 2016-02-24 |
| 3 | Drawing [24-02-2016(online)].pdf | 2016-02-24 |
| 4 | Description(Complete) [24-02-2016(online)].pdf | 2016-02-24 |
| 5 | Other Patent Document [05-07-2016(online)].pdf | 2016-07-05 |
| 6 | Form 26 [05-07-2016(online)].pdf | 2016-07-05 |
| 7 | 201641006387-Power of Attorney-110716.pdf | 2016-07-29 |
| 8 | 201641006387-Form 1-110716.pdf | 2016-07-29 |
| 9 | 201641006387-Correspondence-F1-PA-110716.pdf | 2016-07-29 |
| 10 | 201641006387-FORM 18 [07-01-2020(online)].pdf | 2020-01-07 |
| 10 | Form 3 [24-02-2016(online)].pdf | 2016-02-24 |
| 11 | 201641006387-FER.pdf | 2022-06-07 |
| 11 | Form 5 [24-02-2016(online)].pdf | 2016-02-24 |
| 1 | 201641006387tkdlE_07-06-2022.pdf |
| 2 | 201641006387tk2E_07-06-2022.pdf |
| 3 | 201641006387sE_07-06-2022.pdf |