Abstract: The present disclosure provides a composition comprising sodium pyrophosphate, and ascorbic acid, which at particular combinatorial weight ratios is useful for the management of formation of bacterial biofilm in the oral cavity. The said composition is also useful in management of bacterial population in the oral cavity.
Claims:1. A composition for management of biofilm forming bacterial growth and biofilm formation in the oral cavity, comprising:
a. sodium pyrophosphate; and
b. ascorbic acid,
wherein sodium pyrophosphate to ascorbic acid w/w ratio in said composition is in the range of 1:0.32-1:0.64.
2. The composition as claimed in claim 1, wherein sodium pyrophosphate to ascorbic acid w/w ratio in said composition is 1:0.05.
3. The composition as claimed in any of the claims 1-2, wherein sodium pyrophosphate weight percentage in said composition is 0.125%
4. The composition as claimed in claim 1, wherein ascorbic acid weight percentage in said composition is in the range of 0.04-0.08%.
5. The composition as claimed in any of the claims 1 or 4, wherein ascorbic acid weight percentage in said composition is 0.0625%.
6. The composition as claimed in any of the claims 1-5, further comprising suitable additives.
7. The composition as claimed in any of the claims 1-6, wherein said composition inhibits biofilm formation in the oral cavity by 60-90%, or inhibits biofilm forming bacterial growth in the oral cavity by 90-100%.
8. A method of management of biofilm formation in the oral cavity, said method comprising:
a. obtaining a composition as claimed in any of the claims 1-6, and
b. contacting said composition with the oral cavity,
wherein said method inhibits biofilm formation in the range of 60-90% in the oral cavity.
9. A method of management of biofilm forming bacterial growth in the oral cavity, said method comprising:
a. obtaining a composition as claimed in any of the claims 1-6; and
b. contacting said composition with the oral cavity
wherein said method inhibits biofilm forming bacterial growth by 90-100% in the oral cavity.
10. A method of concurrent management of biofilm formation and biofilm forming bacterial growth in the oral cavity, said method comprising:
a. obtaining a composition as claimed in any of the claims 1-6; and
b. contacting said composition with the oral cavity,
wherein said method inhibits biofilm formation in the range of 60-90%, and inhibits biofilm forming bacterial growth by 90-100% in the oral cavity.
11. A method of preparing a composition as claimed in any of the claims 1-5.
12. A method of preparing a composition as claimed in any of the claims 1-6.
Dated this August 2016
, Description:As Attached
| # | Name | Date |
|---|---|---|
| 1 | Form 5 [24-08-2016(online)].pdf | 2016-08-24 |
| 2 | Form 3 [24-08-2016(online)].pdf | 2016-08-24 |
| 3 | Drawing [24-08-2016(online)].pdf | 2016-08-24 |
| 4 | Description(Complete) [24-08-2016(online)].pdf | 2016-08-24 |
| 5 | Other Patent Document [28-09-2016(online)].pdf | 2016-09-28 |
| 6 | Form 26 [28-09-2016(online)].pdf | 2016-09-28 |