This application is divided out of Indian Patent Application No.190/KOLNP/2007
The present invention relates to the use of polysaccharide compounds containing non-polymer siloxane graft(s) in cosmetics, and to compositions comprising them, and also to novel polysaccharide compounds containing non-polymer siloxane graft(s).
In the cosmetics field, it is especially sought to improve the cosmetic properties of keratin materials, such as the hair and the skin, and more particularly sensitized hair, i.e. hair that has become damaged or embrittled, especially due to the chemical action of atmospheric agents and/or of hair treatments such as permanent-waving, dyeing or bleaching.
With this aim, it is common practice to use complementary cosmetic agents known as conditioning agents, for example cationic polymers or silicones, which are intended mainly to repair or limit the harmful or undesirable effects induced by the various treatments or attacking factors to which hair fibres are more or less repeatedly subjected. These conditioning agents also improve the cosmetic behaviour of natural hair.
Other conditioning agents, such as the amphoteric polysaccharides described in document US 6 066 727 may be used in cosmetic hair compositions.
However, these conditioning agents are not always very efficient as regards conditioning and remanence of cosmetic properties. After several uses, the hair becomes laden and lacks lightness and suppleness.
The Applicant has found, surprisingly and unexpectedly, that the use of polysaccharide compounds containing non-polymer siloxane graft(s) in cosmetics, makes it possible to overcome the drawbacks described above and to obtain excellent cosmetic properties such as an excellent conditioning and protecting effect on the hair, good disentangling of the hair, softness and a smoothing effect on keratin fibres.
Such compounds and the process for preparing them are

described in the article "Cellulose fiber/poly(ethylene-co-methacrylic acid) composites with ionic interphase." de Xiaolin Cai et al, Composites Part A 34,. 2003, pages 1075-1084.
In addition, the use of these polysaccharide compounds containing non-polymer siloxane graft(s) leads to good remanence of these properties, even after washing the hair several times, without observing an excessive deposit that would lead to laden, non-maleable and non-supple hair.
These conditioning agents also give the skin cosmetic properties such as good moisturization.
One subject of the present invention is thus the use of polysaccharide compounds containing non-polymer siloxane graft(s) as described below in cosmetics, especially for the cosmetic treatment of keratin materials, such as caring for and protecting the hair, hairstyling, permanent-waving, relaxing, dyeing or bleaching the hair, or alternatively cleansing and care of the skin.
Another subject of the invention is a cosmetic composition comprising at least one polysaccharide compound containing non-polymer siloxane graft(s) as described below, in a cosmetically acceptable medium.
A subject of the invention is also novel compounds as described below.
Other subjects, characteristics, aspects and advantages of the invention will emerge even more clearly on reading the description and the various examples that follow.
The polysaccharide compounds containing non-polymer siloxane graft(s) used according to the invention may be obtained by reaction of a polysaccharide and a siloxane compound corresponding to formula (I):
in which:

R represents a linear or branched C1-C12 and preferably C1-C8
alkyl group, or a linear or branched C2-C8 alkenyl group,
A represents a linear or branched, saturated or unsaturated,
optionally hydroxylated C1-C22 divalent hydrocarbon-based
group, which may contain a hetero atom N, O or S in the chain,
Z represents -NHR4, -+NR1R2R3 X", -C=N, -SH, -OH, a guanidine
group or guanidinium salt, or a sulfonate, sulfate, phosphate or
phosphonate salt, the salts possibly being organic or mineral,
C1" being preferred as anion and Na+ being preferred as cation,
R4 represents a hydrogen atom or a linear or branched C1-C22 and
preferably C1-C18 alkyl group, optionally bearing at least one
hydroxy] and/or quaternary ammonium substituent,
R1, R2 and R3 represent, independently of each other, a hydrogen atom
or a linear or branched C1-C22 and preferably C1-C18 alkyl
group, optionally bearing at least one hydroxyl substituent, and
X represents a mineral or organic anion, for example a halogen
atom such as a bromine or chlorine atom, the chlorine atom being particularly preferred, or an acetate, a citrate, a lactate, an oleate or a behenate.
The polysaccharide is preferably a cellulose, a hemicellulose, a lignocellulose, a starch, an inulin, a guar gum, a xanthan gum, a pullulan, an agar-agar, a sodium, potassium or ammonium alginate, a carrageenan, a dextran, a furcellaran, a gellan gum, a gum arabic, a gum tragacanth, a hyaluronic acid, a konjac mannan, a lignin sulfonate, a carob gum, a partially N-acetylated chitin, a pectin, a polydextrose, a rhamsan gum or a welan gum.
More preferably, the polysaccharide is a cellulose, a hemicellulose, a carboxymethylcellulose, a hydroxyethylcellulose, a hydroxypropylcellulose, a hydroxypropylmethylcellulose, a methyl-cellulose, a lignocellulose, a starch, a starch acetate, a hydroxyethyl starch, a hydroxypropyl starch, an inulin, a guar gum, a carboxymethylguar gum, a carboxymethylhydroxypropylguar gum, a hydroxyethylguar gum, a hydroxypropylguar gum or a xanthan gum.
The polysaccharide preferably has a weight-average molecular

mass between 500 and 15 000 000 and better still between 1000 and 10 000 000.
As examples of linear or branched C1-C12, preferably C1-C8 and even more preferably C1-C4 alkyl groups, mention may be made especially of methyl, ethyl, n-propyl, isopropyl, n-butyl and tert-butyl groups.
As examples of linear or branched C2-Cs and preferably C2-C4 alkenyl groups, mention may be made especially of vinyl, allyl, crotonyl, butenyl, isobutenyl and tert-butenyl groups.
Examples of linear or branched, saturated or unsaturated C1-C22, preferably C1-C18 and better still C1-C8 divalent hydrocarbon-based groups that may especially be mentioned include linear or branched alkylene groups, such as methylene, ethylene, n-propylene, isopropylene, n-butylene, tert-butylene, hexylene or octylene groups; linear or branched C2-C8 alkylene groups, such as vinylene, allylene, crotonylene, butenylene, isobutenylene, tert-butenylene, hexenylene or octenylene. These groups may also bear at least one hydroxyl substituent and/or may comprise an N, O or S hetero atom in the chain.
Examples of C1-C22 and preferably C1-C18 alkyl groups that may especially be mentioned include linear or branched C1-C4 alkyl groups, such as methyl, ethyl, n-propyl, isopropyl, n-butyl or tert-butyl groups, and linear or branched C12-C18 alkyl groups, such as lauryl, myristyl, cetyl or stearyl groups.
The amphoteric polysaccharide compounds containing non-polymer siloxane graft(s) that are most particularly preferred in the invention are those obtained by reaction:
of a polysaccharide chosen from a cellulose, a hemi cellulose, a carboxymethylcellulose, a hydroxyethylcellulose, a hydroxy-propylcellulose, a hydroxypropylmethylcellulose, a methyl-cellulose, a lignocellulose, a starch, a starch acetate, a hydroxyethyl starch, a hydroxypropyl starch, an inulin, a guar gum, a carboxymethylguar gum, a carboxymethylhydroxy-propylguar gum, a hydroxyethylguar gum, a hydroxypropylguar gum and a xanthan gum; and

of a of a siloxane compound corresponding to formula (I):

in which:
R represents a linear or branched C1-C4 alkyl group, such as
methyl, ethyl, n-propyl, isopropyl, n-butyl or tert-butyl, or a linear or branched C2-C=alkenyl group, such as vinyl, allyl, crotonyl, butenyl, isobutenyl or tert-butenyl,
A represents a linear or branched, saturated or unsaturated,
optionally hydroxylated C1-C18 divalent hydrocarbon-based group, which may contain an N, O or S hetero atom in the chain, such as methylene, ethylene, n-propylene, isopropylene, n-butylene, tert-butylene, hexylene, octylene, dodecylene, hexadecylene or octadecylene or a linear or branched C2-Cg alkenylene group, such as vinylene, allylene, crotonylene, butenylene, isobutenylene, tert-butenylene, hexenylene or octenylene,
Z represents -NHR4, -+NR,R2R3 X', -ON, -SH, -OH, a guanidine
group OT guanidinium salt, or a sulfonate, sulfate, phosphate or phosphonate salt, the salts possibly being organic or mineral, C1 being preferred as anion and Na+ being preferred as cation,
R4 represents a hydrogen atom or a linear or branched C1-C4 alkyl
group, such as methyl, ethyl, n-propyl, isopropyl, n-butyl or tert-butyl, or a linear or branched C12-C1s alkyl group, such as lauryl, myristyl, cetyl or stearyl, optionally bearing at least one hydroxyl and/or quaternary ammonium substituent, R1, R2 and R3 represent, independently of each other, a hydrogen atom or a linear or branched C1-C4 alkyl group, such as methyl, ethyl, n-propyl, isopropyl, n-butyl or tert-butyl, or a linear or branched C12-C1s alkyl group, such as lauryl, myristyl, cetyl or

stearyl, optionally bearing at least one hydroxyl substituent,
and
X represents a halogen atom, an acetate, a citrate, a lactate, an
oleate or a behenate.
The amphoteric polysaccharide compounds according to the invention may be prepared via the process described in "Interaction of silane coupling agents with cellulose", American Chemical Society, Langmuir 2002, 18, 3203-3208, or via the process described in "Cellulose fiber/poly(ethylene-co-methacrylic acid) composites with ionic interphase" de Xiaolin Cai et al, Composites Part A 34,. 2003, pages 1075-1084.
The polysaccharide compounds containing non-polymer siloxane graft(s) as described above are used in cosmetics, and especially for the cosmetic treatment of keratin materials, such as caring for and protecting the hair, as a conditioning agent for hold and discipline of the hairstyle, as a fixing agent; but also for cleansing and caring for the skin and for making up the skin, the lips and the nails.
A subject of the present invention is also a cosmetic composition comprising, in a cosmetically acceptable medium, at least one polysaccharide compound containing non-polymer siloxane graft(s) as described above, preferably in an amount ranging from 0.05% to 50% by weight and better still from 0.5% to 25% by weight relative to the total weight of the composition.
The term "cosmetically acceptable medium" means a medium that is compatible with any keratin material, such as the skin, the hair, the nails, the eyelashes, the eyebrows and the lips and any other area of body or facial skin.
The cosmetically acceptable medium may consist solely of water or of a mixture of water and of a cosmetically acceptable solvent such as a C1-C4 lower alcohol, such as ethanol, isopropanol, tert-butanol or n-butanol; alkylene polyols, for instance propylene glycol; polyol ethers; and mixtures thereof.
The composition according to the invention may also comprise one or more standard additives that are well known in the art, such as

anionic, cationic, nonionic, amphoteric or zwitterionic surfactants, anionic, cationic, nonionic, amphoteric or zwitterionic polymers, thickeners, nacreous agents, opacifiers, UV-screening agents, fragrances, mineral, plant and/or synthetic oils, fatty acid esters, dyes, volatile or non-volatile, organomodified or non-organomodified, cyclic or acyclic, branched or unbranched silicones, mineral or organic, natural or synthetic particles, preserving agents and pH stabilizers.
A person skilled in the art will take care to select the optional additives and the amount thereof such that they do not harm the properties of the compositions of the present invention.
These additives are generally present in the composition according to the invention in an amount ranging from 0 to 20% by weight relative to the total weight of the composition.
The cosmetic compositions in accordance with the invention may be in the form of a mousse, a gel, a spray or a lacquer and may be used in rinse-out or leave-in application.
The compositions in accordance with the invention may be used as hair products, especially rinse-out or leave-in products, and in particular for washing, caring for and/or conditioning the hair, holding the hairstyle, and shaping, dyeing, bleaching, permanently reshaping or relaxing the hair.
The compositions of the invention may also be used as care or hygiene products such as protective, treating or care creams for the face, the hands or the body, protective or care body milks, gels or mousses for caring for or cleansing the skin, or alternatively as products for making up or for removing makeup from the skin, the lips, the nails and the eyelashes.
Another subject of the present invention consists of novel polysaccharide compounds containing non-polymer siloxane graft(s) obtained by reaction of polysaccharide P' with a siloxane compound of formula (I) as described above.
P' represents a polysaccharide chain chosen from a hemi-cellulose, a lignocellulose, a starch, an inulin, a guar gum, a xanthan gum, a pullulan, an agar-agar, a sodium, potassium or ammonium

alginate, a carrageenan, a dextran, a furcellaran, a gellan gum, a gum arabic, a gum tragacanth, a hyaluronic acid, a konjac mannan, a lignin sulfonate, a carob gum, a partially N:-acetylated chitin, a pectin, a polydextrose, a rhamsan gum and a welan gum, preferably having a weight-average molecular mass of between 500 and 15 000 000 and better still between 1000 and 10 000 000.
More preferably, the polysaccharide chain is a hemicellulose, a carboxymethylcellulose, a hydroxyethylcellulose, a hydroxypropyl-cellulose, a hydroxypropylmethylcellulose, a methylcellulose, a lignocellulose, a starch, a starch acetate, a hydroxyethyl starch, a hydroxj'propyl starch, an inulin, a guar gum, a carrboxymethylguar gum, a carboxymethylhydroxypropylguar gum, a hydroxyethyl guar gum, a hydroxypropylguar gum or a xanthan gum.
EXAMPLES
Example 1
20 g of hydroxyethylcellulose are dispersed in 480 ml of an 80/20 ethanol/water mixture, at room temperature. 15.93 g of aminopropyltriethoxysilane (APTES) diluted in 50 ml of an 80/20 ethanol/water mixture are introduced.
The mixture is stirred for 2 hours at room temperature. The precipitate is isolated by centrifugation and is dried in an oven under vacuum at 40°C.
The product is then heated at 110°C under an argon atmosphere for 2 hours. 14.5 g of a yellow powder are thus obtained.
Example 2
20 g of hydroxyethylcellulose are dispersed in 480 ml of an 80/20 ethanol/water mixture, at room temperature. 15.93 g of aminopropyltriethoxysilane (APTES) diluted in 50 ml of an 80/20 ethanol/water mixture are introduced.
The mixture is stirred for 2 hours at room temperature. The precipitate is isolated by centrifugation and is dried in an oven under

vacuum at 40°C.
The product is then heated at 110°C under a vacuum of 263 Pa (2 mmHg) for 2 hours. 14 g of a yellow powder are thus obtained.
Example 3: Shampoo
A shampoo was prepared using the following ingredients, the amounts of which are given as weight percentages of active material relative to the total weight of the composition:

Example 4: Conditioner
A conditioner was prepared using the following ingredients, the amounts of which are given as weight percentages of active material relative to the total weight of the composition:


Examples 5-7
Dye compositions were prepared using the following ingredients, the amounts of which are given as weight percentages of active material relative to the total weight of the composition:



At the time of use, each dye composition described above was mixed weight-for-weight with a 20-volumes hydrogen peroxide solution (6% by weight).
The mixtures thus prepared were applied for 30 minutes to locks of natural or permanent-waved grey hair containing 90% white hairs. The locks were then rinsed, washed with a standard shampoo, rinsed again and then dried.
The hair was dyed in a golden-blond shade for each of the Examples 4 to 6.

Example 8
Another dye composition was prepared using the following ingredients, the amounts of which are given as weight percentages of active material relative to the total weight of the composition:

This composition is mixed at the time of use with an oxidizing

composition in emulsion form containing as oxidizing agent 7.5% hydrogen peroxide, in a proportion of 1 part by weight of dye composition per 1.5 parts by weight of oxidizing composition. The mixture obtained is applied to locks of natural hair containing 90% white hairs, and is left to act for 30 minutes. After rinsing, washing with shampoo and drying, hair dyed in a strong coppery-red light-chestnut shade is obtained.
Example 9
The following compositions were prepared, the percentages indicated being weight percentages relative to the total weight of the composition:



The dye composition was mixed, at the time of use, in a plastic bow] and
for 2 minutes, with the oxidizing composition given above, in a
proportion of 1 part of dye composition per 1.5 parts of oxidizing
composition.
The mixture obtained was applied to locks of natural hair containing
90% white hairs, and was left to act for 30 minutes.

The locks were then rinsed with water, washed with shampoo, rinsed again with water and then dried and disentangled.
The hair was then dyed in a strong light-chestnut shade.
Example 10
Another dye composition was prepared using the following ingredients, the amounts of which are given as weight percentages of active material relative to the total weight of the composition:


WE CLAIM:
1. Cosmetic use of polysaccharide compounds containing
non-polymer siloxane graft(s) that may be obtained by reacting a
polysaccharide and a siloxane compound corresponding to formula (I):

in which:
R represents a linear or branched C1-C12 alkyl group, or a linear
or branched C2-C8 alkenyl group,
A represents a linear or branched, saturated or unsaturated,
optionally hydroxylated C1-C22 divalent hydrocarbon-based
group, which may contain a hetero atom N, O or S in the chain,
Z represents -NHR4, -+NR,R2R3 X', -ON, -SH, -OH, a guanidine
group or guanidinium salt, or a sulfonate, sulfate, phosphate or
phosphonate salt, the salts possibly being organic or mineral,
R4 represents a hydrogen atom or a linear or branched C1-C22 alkyl
group, optionally bearing at least one hydroxyl and/or
quaternary ammonium substituent, R1, R2 and R3 represent, independently of each other, a hydrogen atom
or a linear or branched C1-C22 alkyl group, optionally bearing
at least one hydroxyl substituent, and
X represents a mineral or organic anion.
2. Use according to Claim 1, characterized in that the
polysaccharide is chosen from a cellulose, a hemicellulose, a carboxy-
methylcellulose, a hydroxyethylcellulose, a hydroxypropylcellulose, a
hydroxypropylmethylcellulose, a methylcellulose, a lignocellulose, a
starch, a starch acetate, a hydroxyethyl starch, a hydroxypropyl starch,
an inulin, a guar gum, a carboxymethylguar gum, a carboxymethyl-
hydroxypropylguar gum, a hydroxyethylguar gum, a hydroxypropyl-

guar gum or a xanthan gum.
3. Use according to Claim 1 or 2, characterized in that R represents a methyl, ethyl, n-propyl, isopropyl, n-butyl, tert-butyl, vinyl, allyl, crotonyl, butenyl, isobutenyl or tert-butenyl group.
4. Use according to any one of the preceding claims, characterized in that A represents a linear or branched C1-C6 alkylene group or a linear or branched C2-C8 alkenylene group, these groups optionally bearing at least one hydroxyl substituent and/or optionally comprising an N, O or S hetero atom in the chain.
5. Use according to Claim 4, characterized in that A represents a methylene, ethylene, n-propylene, isopropylene, n-butylene, tert-butylene, hexylene, octylene, vinylene, allylene, crotonylene, butenylene, isobutenylene, tert-butenylene, hexenylene or octenylene group, optionally bearing a hydroxyl substituent and/or optionally comprising an N, O or S hetero atom in the chain.
6. Use according to any one of the preceding claims, characterized in that the linear or branched C1-C22 alkyl group is a linear or branched C1-C4 alkyl group or a linear or branched C12-C18 alkyl group.
7. Use according to Claim 6, characterized in that the linear or branched C1-C22 alkyl group is a methyl, ethyl, n-propyl, isopropyl, n-butyl, tert-butyl, lauryl, myristyl, cetyl or stearyl group.
8. Use according to any one of the preceding claims, characterized in that X represents a halogen atom, an acetate, a citrate, a lactate, an oleate or a behenate.
9. Use according to any one of the preceding claims, for the cosmetic treatment of keratin materials.
10. Use according to Claim 9, for caring for and protecting the hair.
11. Use according to Claim 9, for cleansing and caring for the skin.
12. Use according to Claim 9, for making up the skin, the lips and nails.
13. Cosmetic composition comprising, in a cosmetically

acceptable medium, at least one polysaccharide compound containing non-polymer siloxane graft(s) as defined in any one of Claims 1 to 8.
14. Cosmetic composition according to Claim 13, characterized in that it comprises the said polysaccharide compound containing non-polymer siloxane graft(s) in an amount ranging from 0.05% to 50% by weight relative to the total weight of the composition.
15. Cosmetic composition according to Claim 14, characterized in that it comprises the said polysaccharide compound containing non-polymer siloxane graft(s) in an amount ranging from 0.5% to 25% by weight relative to the total weight of the composition.
16. Cosmetic composition according to any one of Claims 13 to 15, characterized in that the cosmetically acceptable medium comprises water or a mixture of water and of at least one organic solvent.
17. Cosmetic composition according to Claim 16, characterized in that the organic solvent is chosen from C1-C4 lower alcohols, alkylene polyols, polyol ethers, and mixtures thereof.
18. Cosmetic composition according to any one of Claims 13 to 17, characterized in that it comprises at least one additive chosen from anionic, cationic, nonionic, amphoteric or zwitterionic surfactants, anionic, cationic, nonionic, amphoteric or zwitterionic polymers, thickeners, nacreous agents, opacifiers, UV-screening agents, fragrances, mineral, plant and/or synthetic oils, fatty acid esters, dyes, volatile or non-volatile, organomodified or non-organomodified, cyclic or acyclic, branched or unbranched silicones, mineral or organic, natural or synthetic particles, preserving agents and pH stabilizers.
19. Polysaccharide compound containing non-polymer siloxane graft(s) obtained by reacting a polysaccharide P"' with a siloxane compound of formula (I) as defined in Claims 1 to 8, P' representing a polysaccharide chain chosen from a hemicellulose, a lignocellulose, a starch, an inulin, a guar gum, a xanthan gum, a pullulan, an agar-agar, a sodium, potassium or ammonium alginate, a

carrageenan, a dextran, a furcellaran, a gellan gum, a gum arable, a gum tragacanth, a hyaluronic acid, a konjac mannan, a lignin sulfonate, a carob gum a partially N-acetylated chitin, a pectin, a polydextrose, a rhamsan gum or a welan gum, preferably having a weight-average molecular mass of between 500 and 15 000 000.
20. Compound according to Claim 19, in which P' represents a hemicellulose, a carboxymethylcellulose, a hydroxyethyl-cellulose, a hydroxypropylcellulose, a hydroxypropylmethylcellulose, a methylcellulose, a lignocellulose, a starch, a starch acetate, a hydroxyethyl starch, a hydroxypropyl starch, an inulin, a guar gum, a carboxymethylguar gum, a carboxymethylhydroxypropylguar gum, a hydroxyethylguar gum, a hydroxypropyl guar gum or a xanthan gum.
21. A cosmetic composition substantially as herein described.
22. A polysaccharide compound substantially as herein described.

The invention discloses the cosmetic use of polysaccharide compounds containing non-polymer siloxane graft(s) that may be obtained by reacting a polysaccharide and a siloxane compound corresponding to the formula (I), especially for the cosmetic treatment of keratin materials. The invention also relates to compositions comprising the said polysaccharide compounds in a cosmetically acceptable medium, and also to certain novel polysaccharide compounds containing non-polymer siloxane graft(s).