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Crystalline Form Of Roxadustat And Its Process For Preparation

Abstract: Abstract The present invention relates to crystalline Roxadustat Form-a and its process for the preparation.

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Patent Information

Application #
Filing Date
19 December 2016
Publication Number
25/2018
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
ipdoipm@drreddys.com
Parent Application

Applicants

Dr. Reddy’s Laboratories Limited
8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana, India -500034 .

Inventors

1. DIVYA JYOTHI KALLEM
H.No. 17-1-382/P/130, Press Colony, Champapet, Saidabad, Hyderabad-500079
2. SALADI VENKATA NARASAYYA
H.No.48-579-5/1, Ganesh Nagar , Chintal, Hyderabad-500054 Telangana, India

Specification

DESC:WE CLAIM:

1) Crystalline Roxadustat Form-a characterized by its powder X-ray diffraction (PXRD) pattern having the peaks at about 5.27, 8.18, 10.55, 11.51, 13.63, 14.51, 17.86, 18.55, 20.26, 20.63 and 24.77 ± 0.20° 2?.
2) Crystalline Roxadustat Form-a substantially as shown in Figure-1.
3) A process for preparation of crystalline Roxadustat Form-a, comprising;
a) Dissolving Roxadustat in solvent comprising acetic acid to obtain the solution and;
b) Isolating crystalline Roxadustat Form-a.
,CLAIMS:WE CLAIM:

1) Crystalline Roxadustat Form-a characterized by its powder X-ray diffraction (PXRD) pattern having the peaks at about 5.27, 8.18, 10.55, 11.51, 13.63, 14.51, 17.86, 18.55, 20.26, 20.63 and 24.77 ± 0.20° 2?.
2) Crystalline Roxadustat Form-a substantially as shown in Figure-1.
3) A process for preparation of crystalline Roxadustat Form-a, comprising;
a) Dissolving Roxadustat in solvent comprising acetic acid to obtain the solution and;
b) Isolating crystalline Roxadustat Form-a.

Documents

Application Documents

# Name Date
1 Form2 Title Page_Provisional_19-12-2016.pdf 2016-12-19
2 Description Provisional_As Filed_19-12-2016.pdf 2016-12-19
3 201641043301-STATEMENT OF UNDERTAKING (FORM 3) [19-12-2016(online)].pdf 2016-12-19
4 201641043301-PROVISIONAL SPECIFICATION [19-12-2016(online)].pdf 2016-12-19
5 201641043301-DRAWINGS [19-12-2016(online)].pdf 2016-12-19
6 201641043301-FORM 3 [18-12-2017(online)].pdf 2017-12-18
7 201641043301-ENDORSEMENT BY INVENTORS [18-12-2017(online)].pdf 2017-12-18
8 201641043301-DRAWING [18-12-2017(online)].pdf 2017-12-18
9 201641043301-COMPLETE SPECIFICATION [18-12-2017(online)].pdf 2017-12-18