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Dihydrobenzofuranyl Alkanamine Derivatives As 5 Ht2 C Agonists

Abstract: Compounds of formula (2) or pharmaceutically acceptable salts thereof are provided: wherein each of R1a, R2a, R3a, Ar, y, and m are as defined herein, which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions containing the compounds, are used to treat a variety of central nervous system disorders such as schizophrenia.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
15 October 2007
Publication Number
07/2008
Publication Type
INA
Invention Field
PHARMACEUTICALS
Status
Email
Parent Application

Applicants

WYETH
FIVE GIRALDA FARMS, MADISON, NEW JERSEY

Inventors

1. GROSS JONATHAN LAIRD
25 WASHINGTON DRIVE, CRANBURY, NJ 08512
2. WILLIAMS MARIA JEAN
2 FROST COURT, FLEMINGTON, NJ 08889
3. STACK GARY PAUL
525 BROOKFIELD LANE, AMBLER, PA 19002
4. GAO HONG
24 REID AVENUE, BELLE MEAD, NJ 08502
5. ZHOU DAHUI
27 CHRISTIAN DRIVE, EAST BRUNSWICK, NJ 08816

Specification

Compounds of formula (2) or pharmaceutically acceptable salts thereof are provided: wherein each of R1a, R2a, R3a, Ar, y, and m are as defined herein, which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions containing the compounds, are used to treat a variety of central nervous system disorders such as schizophrenia.

Documents

Application Documents

# Name Date
1 3951-KOLNP-2007-INTERNATIONAL PUBLICATION-1.pdf 2018-09-10
1 abstract-03951-kolnp-2007.jpg 2011-10-08
2 3951-KOLNP-2007-INTERNATIONAL PUBLICATION-2.pdf 2018-09-10
2 3951-KOLNP-2007-PCT PRIORITY DOCUMENT NOTIFICATION.pdf 2011-10-08
3 3951-KOLNP-2007-INTERNATIONAL PUBLICATION-3.pdf 2018-09-10
3 3951-kolnp-2007-form-18.pdf 2011-10-08
4 ABANDONED LETTER.pdf 2016-12-02
4 3951-KOLNP-2007-FORM 3-1.1.pdf 2011-10-08
5 FIRST EXAMINATION LETTER.pdf 2016-12-02
5 3951-KOLNP-2007-CORRESPONDENCE OTHERS 1.1.pdf 2011-10-08
6 3951-KOLNP-2007-ABANDONED LETTER.pdf 2016-10-06
6 03951-kolnp-2007-international search report.pdf 2011-10-08
7 3951-KOLNP-2007-FIRST EXAMINATION REPORT.pdf 2016-10-06
7 03951-kolnp-2007-gpa.pdf 2011-10-08
8 3951-KOLNP-2007_EXAMREPORT.pdf 2016-06-30
8 03951-kolnp-2007-form 5.pdf 2011-10-08
9 03951-kolnp-2007-abstract.pdf 2011-10-08
9 03951-kolnp-2007-form 3.pdf 2011-10-08
10 03951-kolnp-2007-claims.pdf 2011-10-08
10 03951-kolnp-2007-form 1.pdf 2011-10-08
11 03951-kolnp-2007-correspondence others.pdf 2011-10-08
12 03951-kolnp-2007-claims.pdf 2011-10-08
12 03951-kolnp-2007-form 1.pdf 2011-10-08
13 03951-kolnp-2007-abstract.pdf 2011-10-08
13 03951-kolnp-2007-form 3.pdf 2011-10-08
14 03951-kolnp-2007-form 5.pdf 2011-10-08
14 3951-KOLNP-2007_EXAMREPORT.pdf 2016-06-30
15 03951-kolnp-2007-gpa.pdf 2011-10-08
15 3951-KOLNP-2007-FIRST EXAMINATION REPORT.pdf 2016-10-06
16 03951-kolnp-2007-international search report.pdf 2011-10-08
16 3951-KOLNP-2007-ABANDONED LETTER.pdf 2016-10-06
17 3951-KOLNP-2007-CORRESPONDENCE OTHERS 1.1.pdf 2011-10-08
17 FIRST EXAMINATION LETTER.pdf 2016-12-02
18 3951-KOLNP-2007-FORM 3-1.1.pdf 2011-10-08
18 ABANDONED LETTER.pdf 2016-12-02
19 3951-KOLNP-2007-INTERNATIONAL PUBLICATION-3.pdf 2018-09-10
19 3951-kolnp-2007-form-18.pdf 2011-10-08
20 3951-KOLNP-2007-PCT PRIORITY DOCUMENT NOTIFICATION.pdf 2011-10-08
20 3951-KOLNP-2007-INTERNATIONAL PUBLICATION-2.pdf 2018-09-10
21 abstract-03951-kolnp-2007.jpg 2011-10-08
21 3951-KOLNP-2007-INTERNATIONAL PUBLICATION-1.pdf 2018-09-10