Generation Of A High Producing Recombinant Chinese Hamster Ovary Cell

Generation Of A High Producing Recombinant Chinese Hamster Ovary Cell Line For Therapeutic Protein Production

Abstract: The present invention concerns a cell line comprising an endogenous dihydroorotate dehydrogenase (DHODH) and glutamine synthetase (GS) genes which are partially or fully inactivated, and its use for producing recombinant proteins.

Patent Information

Application #

Filing Date

23 March 2023

Publication Number

47/2023

Publication Type

INA

Invention Field

BIOTECHNOLOGY

Status

Email

Parent Application

Applicants

SANOFI

46 avenue de la Grande Armée 75017 PARIS

Inventors

1. DUMAS, Bruno Louis

c/o Sanofi Département Brevets 54 rue La Boétie 75008 PARIS

2. LOUNIS, Mohammed Nabil

c/o Sanofi Patent Department 54 Rue La Boétie 75008 PARIS

Specification

Documents

Application Documents

#	Name	Date
1	202317020584.pdf	2023-03-23
2	202317020584-TRANSLATIOIN OF PRIOIRTY DOCUMENTS ETC. [23-03-2023(online)].pdf	2023-03-23
3	202317020584-STATEMENT OF UNDERTAKING (FORM 3) [23-03-2023(online)].pdf	2023-03-23
4	202317020584-Sequence Listing in txt [23-03-2023(online)].txt	2023-03-23
5	202317020584-Sequence Listing in PDF [23-03-2023(online)].pdf	2023-03-23
6	202317020584-POWER OF AUTHORITY [23-03-2023(online)].pdf	2023-03-23
7	202317020584-FORM 1 [23-03-2023(online)].pdf	2023-03-23
8	202317020584-DRAWINGS [23-03-2023(online)].pdf	2023-03-23
9	202317020584-DECLARATION OF INVENTORSHIP (FORM 5) [23-03-2023(online)].pdf	2023-03-23
10	202317020584-COMPLETE SPECIFICATION [23-03-2023(online)].pdf	2023-03-23
11	202317020584-Proof of Right [28-08-2023(online)].pdf	2023-08-28
12	202317020584-FORM 3 [28-08-2023(online)].pdf	2023-08-28
13	202317020584-FORM 18 [23-08-2024(online)].pdf	2024-08-23