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Genetically Modified Microorganism For Producing 3 Hydroxyhexanedioic Acid, (E) Hex 2 Enedioic Acid And/Or Hexanedioic Acid, And Production Method For Said Chemicals

Abstract: Disclosed are a genetically modified microorganism capable of producing 3-hydroxyhexanedioic acid, (E)-hex-2-enedioic acid and/or hexanedioic acid at a high yield, and a production method for 3-hydroxyhexanedioic acid, (E)-hex-2-enedioic acid and/or hexanedioic acid using said genetically modified microorganism. The genetically modified microorganism has the ability to produce 3-hydroxyhexanedioic acid, (E)-hex-2-enedioic acid and/or hexanedioic acid, and has been modified so as to disrupt the function of pyruvate kinase and to enhance the activity of phosphoenolpyruvate carboxykinase and the activity of enzymes that catalyze a reaction for generating 3-hydroxyadipyl-CoA by reducing 3-oxoadipyl-CoA.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
30 November 2021
Publication Number
50/2021
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
patent@depenning.com
Parent Application

Applicants

TORAY INDUSTRIES, INC.
1-1, Nihonbashi-Muromachi 2-chome, Chuo-ku, Tokyo 1038666

Inventors

1. ISOBE, Kyohei
c/o Basic Research Center, Toray Industries, Inc., 10-1, Tebiro 6-chome, Kamakura-shi, Kanagawa 2488555
2. KAWAMURA, Kenji
c/o Basic Research Center, Toray Industries, Inc., 10-1, Tebiro 6-chome, Kamakura-shi, Kanagawa 2488555
3. YAMADA, Katsushige
c/o Basic Research Center, Toray Industries, Inc., 10-1, Tebiro 6-chome, Kamakura-shi, Kanagawa 2488555

Specification

Documents

Application Documents

# Name Date
1 202147055408-FORM 18 [05-04-2023(online)].pdf 2023-04-05
1 202147055408.pdf 2021-11-30
2 202147055408-Correspondence_GPA_11-10-2022.pdf 2022-10-11
2 202147055408-STATEMENT OF UNDERTAKING (FORM 3) [30-11-2021(online)].pdf 2021-11-30
3 202147055408-SEQUENCE LISTING(PDF) [30-11-2021(online)].pdf 2021-11-30
3 202147055408-FORM-26 [04-02-2022(online)].pdf 2022-02-04
4 202147055408-SEQUENCE LISTING [30-11-2021(online)].txt 2021-11-30
4 202147055408-AMMENDED DOCUMENTS [21-01-2022(online)].pdf 2022-01-21
5 202147055408-PROOF OF RIGHT [30-11-2021(online)].pdf 2021-11-30
5 202147055408-FORM 13 [21-01-2022(online)].pdf 2022-01-21
6 202147055408-PRIORITY DOCUMENTS [30-11-2021(online)].pdf 2021-11-30
6 202147055408-MARKED COPIES OF AMENDEMENTS [21-01-2022(online)].pdf 2022-01-21
7 202147055408-RELEVANT DOCUMENTS [21-01-2022(online)].pdf 2022-01-21
7 202147055408-FORM 1 [30-11-2021(online)].pdf 2021-11-30
8 202147055408-DECLARATION OF INVENTORSHIP (FORM 5) [30-11-2021(online)].pdf 2021-11-30
8 202147055408-FORM 3 [29-12-2021(online)].pdf 2021-12-29
9 202147055408-COMPLETE SPECIFICATION [30-11-2021(online)].pdf 2021-11-30
10 202147055408-FORM 3 [29-12-2021(online)].pdf 2021-12-29
10 202147055408-DECLARATION OF INVENTORSHIP (FORM 5) [30-11-2021(online)].pdf 2021-11-30
11 202147055408-RELEVANT DOCUMENTS [21-01-2022(online)].pdf 2022-01-21
11 202147055408-FORM 1 [30-11-2021(online)].pdf 2021-11-30
12 202147055408-PRIORITY DOCUMENTS [30-11-2021(online)].pdf 2021-11-30
12 202147055408-MARKED COPIES OF AMENDEMENTS [21-01-2022(online)].pdf 2022-01-21
13 202147055408-PROOF OF RIGHT [30-11-2021(online)].pdf 2021-11-30
13 202147055408-FORM 13 [21-01-2022(online)].pdf 2022-01-21
14 202147055408-SEQUENCE LISTING [30-11-2021(online)].txt 2021-11-30
14 202147055408-AMMENDED DOCUMENTS [21-01-2022(online)].pdf 2022-01-21
15 202147055408-SEQUENCE LISTING(PDF) [30-11-2021(online)].pdf 2021-11-30
15 202147055408-FORM-26 [04-02-2022(online)].pdf 2022-02-04
16 202147055408-STATEMENT OF UNDERTAKING (FORM 3) [30-11-2021(online)].pdf 2021-11-30
16 202147055408-Correspondence_GPA_11-10-2022.pdf 2022-10-11
17 202147055408.pdf 2021-11-30
17 202147055408-FORM 18 [05-04-2023(online)].pdf 2023-04-05