Glucagon Like Peptide 1 (Glp 1) Agonist Analog, Process Of Preparation

Glucagon Like Peptide 1 (Glp 1) Agonist Analog, Process Of Preparation And Uses Thereof

Abstract: The present disclosure relates to an analog of glucagon-like peptide-1 (glp-1)receptor agonist. The present disclosure provides analogs of glucagon-like peptide-1 (glp-1) receptor agonist wherein, the amino acid at position 2 of the 5 glucagon-like peptide-1 (glp-1)receptor agonist is replaced with D-Alanine. The analogs of glucagon-like peptide-1 (glp-1) have one or more properties of prolonged half-life, better pharmacokinetic profile, retained biological activity, and being advantageous for relieving the patient's burden by reducing the dosing frequency and dose. The present disclosure further provides processes for 10 preparing synthetic glucagon-like peptide-1 (glp-1) analogs.

Patent Information

Application #

Filing Date

27 August 2021

Publication Number

36/2021

Publication Type

INA

Invention Field

BIO-CHEMISTRY

Status

Email

Info@khuranaandkhurana.com

Parent Application

Applicants

ENZENE BIOSCIENCES LIMITED

Plot No. 165/1/26, Block T, Bhosari MIDC, Pune Maharashtra 411 026

Inventors

1. GADGIL, Himanshu

B1101, Park Granduer, Balewadi High Street, Baner, Pune Maharashtra 411045

2. BANERJEE, Abir

D204, Anjor Apartments, Baner, Pune Maharashtra 411045

3. LONDHE, Harshita

House No. 644, Panchanath Colony, Pachpirchowk, Kalewadi, Pune Maharashtra 411017

4. MAGDUM, Deepali

Baba Jarag Nagar, Lay Out No. 4, 46/B, Kolhapur Maharashtra 416007

5. LEVIN, Daniel

220, Straight Crest DR La Canada, California 91011

6. SINGH, Sandeep

Alkem Laboratories Limited Devashish Building, Alkem House, Senapatibapat Road, Lower Parel, Mumbai Maharashtra 400 013

Specification

Documents

Application Documents

#	Name	Date
1	202147038826-FORM 18 [10-01-2023(online)].pdf	2023-01-10
1	202147038826-STATEMENT OF UNDERTAKING (FORM 3) [27-08-2021(online)].pdf	2021-08-27
2	202147038826-FORM-26 [22-02-2022(online)].pdf	2022-02-22
2	202147038826-POWER OF AUTHORITY [27-08-2021(online)].pdf	2021-08-27
3	202147038826-FORM 3 [21-02-2022(online)].pdf	2022-02-21
3	202147038826-FORM 1 [27-08-2021(online)].pdf	2021-08-27
4	202147038826-Proof of Right [31-12-2021(online)].pdf	2021-12-31
4	202147038826-DRAWINGS [27-08-2021(online)].pdf	2021-08-27
5	202147038826-DECLARATION OF INVENTORSHIP (FORM 5) [27-08-2021(online)].pdf	2021-08-27
5	202147038826.pdf	2021-10-19
6	202147038826-COMPLETE SPECIFICATION [27-08-2021(online)].pdf	2021-08-27
7	202147038826-DECLARATION OF INVENTORSHIP (FORM 5) [27-08-2021(online)].pdf	2021-08-27
7	202147038826.pdf	2021-10-19
8	202147038826-DRAWINGS [27-08-2021(online)].pdf	2021-08-27
8	202147038826-Proof of Right [31-12-2021(online)].pdf	2021-12-31
9	202147038826-FORM 1 [27-08-2021(online)].pdf	2021-08-27
9	202147038826-FORM 3 [21-02-2022(online)].pdf	2022-02-21
10	202147038826-POWER OF AUTHORITY [27-08-2021(online)].pdf	2021-08-27
10	202147038826-FORM-26 [22-02-2022(online)].pdf	2022-02-22
11	202147038826-STATEMENT OF UNDERTAKING (FORM 3) [27-08-2021(online)].pdf	2021-08-27
11	202147038826-FORM 18 [10-01-2023(online)].pdf	2023-01-10