“Glucagon Receptor Antagonists, Preparation And Therapeutic Uses”

Abstract: The present invention discloses novel compounds of Formula I, or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like.

Patent Information

Application #

Filing Date

11 April 2008

Publication Number

16/2009

Publication Type

INA

Invention Field

PHARMACEUTICALS

Status

Email

Parent Application

Applicants

ELI LILLY AND COMPANY

Lilly Corporate Center Indianapolis Indiana 46285 USA.

Inventors

1. LI, Jianke

1413 Aspen Glen Drive Hamden Connecticut 06518 USA

2. ZHU, Guoxin

10532 Titan Run Carmel Indiana USA

Specification

This invention relates to compounds that are antagonists or inverse agaonists of the glucagon receptor, and to pharmaceutical compositions thereof, and the uses of these compounds and compositions in the treatment of the human or animal body. The present compounds show a high affinity and.................

Documents

Application Documents

#	Name	Date
1	1471-KOLNP-2008-(16-04-2008)-FORM-13.pdf	2008-04-16
1	1471-KOLNP-2008-AbandonedLetter.pdf	2024-07-08
2	Form-5.pdf	2011-10-07
2	1471-KOLNP-2008-FER.pdf	2017-03-23
3	Form-3.pdf	2011-10-07
3	1471-KOLNP-2008-FORM 13.pdf	2017-03-23
4	1471-KOLNP-2008-FORM-18.pdf	2016-07-29
4	Form-1.pdf	2011-10-07
5	1471-KOLNP-2008-CORRESPONDENCE.pdf	2011-10-07
5	1471-KOLNP-2008-(15-01-2014)-CORRESPONDENCE.pdf	2014-01-15
6	1471-KOLNP-2008-(26-03-2013)-CORRESPONDENCE.pdf	2013-03-26
6	1471-KOLNP-2008-(02-07-2012)-OTHERS.pdf	2012-07-02
7	1471-KOLNP-2008-(02-07-2012)-FORM-1.pdf	2012-07-02
7	1471-KOLNP-2008-(02-07-2012)-CORRESPONDENCE.pdf	2012-07-02
8	1471-KOLNP-2008-(02-07-2012)-FORM-1.pdf	2012-07-02
8	1471-KOLNP-2008-(02-07-2012)-CORRESPONDENCE.pdf	2012-07-02
9	1471-KOLNP-2008-(26-03-2013)-CORRESPONDENCE.pdf	2013-03-26
9	1471-KOLNP-2008-(02-07-2012)-OTHERS.pdf	2012-07-02
10	1471-KOLNP-2008-(15-01-2014)-CORRESPONDENCE.pdf	2014-01-15
10	1471-KOLNP-2008-CORRESPONDENCE.pdf	2011-10-07
11	1471-KOLNP-2008-FORM-18.pdf	2016-07-29
11	Form-1.pdf	2011-10-07
12	Form-3.pdf	2011-10-07
12	1471-KOLNP-2008-FORM 13.pdf	2017-03-23
13	Form-5.pdf	2011-10-07
13	1471-KOLNP-2008-FER.pdf	2017-03-23
14	1471-KOLNP-2008-AbandonedLetter.pdf	2024-07-08
14	1471-KOLNP-2008-(16-04-2008)-FORM-13.pdf	2008-04-16

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