Abstract: The present invention discloses novel compounds of Formula I, or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like.
This invention relates to compounds that are antagonists or inverse agonists of the glucagon receptor, and to pharmaceutical compositions therof, and the uses of these compounds and composotions in the treatment of the human or animal body..........................................
| # | Name | Date |
|---|---|---|
| 1 | 1500-KOLNP-2008-AbandonedLetter.pdf | 2024-07-08 |
| 1 | Form-5.pdf | 2011-10-07 |
| 2 | Form-3.pdf | 2011-10-07 |
| 2 | 1500-KOLNP-2008-FER.pdf | 2017-01-17 |
| 3 | Form-1.pdf | 2011-10-07 |
| 3 | 1500-KOLNP-2008-FORM 13.pdf | 2017-01-07 |
| 4 | 1500-kolnp-2008-form 18.pdf | 2011-10-07 |
| 4 | 1500-KOLNP-2008-(15-01-2014)-CORRESPONDENCE.pdf | 2014-01-15 |
| 5 | 1500-KOLNP-2008-(26-03-2013)-CORRESPONDENCE.pdf | 2013-03-26 |
| 5 | 1500-KOLNP-2008-CORRESPONDENCE.pdf | 2011-10-07 |
| 6 | 1500-KOLNP-2008-(02-07-2012)-CORRESPONDENCE.pdf | 2012-07-02 |
| 6 | 1500-KOLNP-2008-(02-07-2012)-FORM-1.pdf | 2012-07-02 |
| 7 | 1500-KOLNP-2008-(02-07-2012)-CORRESPONDENCE.pdf | 2012-07-02 |
| 7 | 1500-KOLNP-2008-(02-07-2012)-FORM-1.pdf | 2012-07-02 |
| 8 | 1500-KOLNP-2008-(26-03-2013)-CORRESPONDENCE.pdf | 2013-03-26 |
| 8 | 1500-KOLNP-2008-CORRESPONDENCE.pdf | 2011-10-07 |
| 9 | 1500-KOLNP-2008-(15-01-2014)-CORRESPONDENCE.pdf | 2014-01-15 |
| 9 | 1500-kolnp-2008-form 18.pdf | 2011-10-07 |
| 10 | Form-1.pdf | 2011-10-07 |
| 10 | 1500-KOLNP-2008-FORM 13.pdf | 2017-01-07 |
| 11 | Form-3.pdf | 2011-10-07 |
| 11 | 1500-KOLNP-2008-FER.pdf | 2017-01-17 |
| 12 | Form-5.pdf | 2011-10-07 |
| 12 | 1500-KOLNP-2008-AbandonedLetter.pdf | 2024-07-08 |
| 1 | Searchstrategyfor1500-KOLNP-2008_11-01-2017.pdf |