“Glucagon Receptor Antagonists, Preparation And Therapeutic Uses”

Abstract: The present invention discloses novel compounds of Formula (I), or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like.

Patent Information

Application #

Filing Date

17 April 2008

Publication Number

16/2009

Publication Type

INA

Invention Field

PHARMACEUTICALS

Status

Email

Parent Application

Applicants

ELI LILLY AND COMPANY

Lilly Corporate Center Indianapolis Indiana 46285 USA.

Inventors

1. CHAPPELL, Mark, Donald

541 Pitney Drive Noblesville Indiana 46062 USA

2. CONNER, Scott, Eugene

8426 Carefree Circle Indianapolis Indiana 46236 USA

3. HIPSKIND, Philip, Arthur

4255 Cabin Court New Palestine Indiana 46163 USA

4. LAMAR, Jason, Eric

6305 East Pleasant Run Parkway South Drive Indianapolis Indiana 46219 USA

5. ZHU, Guoxin

21F 1 Corporate Avenue Number 222 Hu Bin Road Shanghai 200021 CHINA

Specification

This invention relates to compounds that are antagonists or inverse agonists of the glucagon receptor, and to pharmaceutical composition thereof, and the uses of these compounds and compositions in the treatment of the human or animal body.....................

Documents

Application Documents

#	Name	Date
1	Form-5.pdf	2011-10-07
2	Form-3.pdf	2011-10-07
3	Form-1.pdf	2011-10-07
4	1546-kolnp-2008-form 18.pdf	2011-10-07
5	1546-KOLNP-2008-CORRESPONDENCE.pdf	2011-10-07
6	1546-KOLNP-2008-(02-07-2012)-OTHERS.pdf	2012-07-02
7	1546-KOLNP-2008-(02-07-2012)-FORM-1.pdf	2012-07-02
8	1546-KOLNP-2008-(02-07-2012)-CORRESPONDENCE.pdf	2012-07-02
9	1546-KOLNP-2008-(26-03-2013)-CORRESPONDENCE.pdf	2013-03-26
10	1546-KOLNP-2008-(15-01-2014)-CORRESPONDENCE.pdf	2014-01-15
11	1546-KOLNP-2008-FORM 13.pdf	2017-01-30
12	1546-KOLNP-2008-FER.pdf	2017-01-30
13	1546-KOLNP-2008-AbandonedLetter.pdf	2024-07-08

Search Strategy

1	SearchStrategy1546_23-01-2017.pdf