The present invention relates to the field of herbal formulation for relaxation and a process of preparing thereof.
More particularly, the present invention provides herbal formulation for relaxation and a process of preparing thereof comprises Valerian extract, which relieves restlessness, calms and relaxes and Melissa leaf extracts, used to calm the over-stimulated nervous system.
Background of the invention:
Few examples of related products are below, which are not fulfilling customer/people requirements.
We have observed so many related products mostly are in Tablet or capsule form and are single ingredients thus they were not fulfilling these days consumer requirement. Few examples are below.
a) Himalaya Mentatsyrup: - Contains mainly Ashwagandha, Thyme leaves, Mandukaparni. Mentat improve mental quotient, memory span and concentration ability. The calming effects of Mentat are beneficial in treating insomnia and convulsions.
b)Lemon Balm capsule:- Lemon Balm is a traditional herbal medicinal product typically used in aromatherapy for its calming effect and for the temporary relief of symptoms of mild anxiety, to aid sleep and for mild digestive complaints such as bloating and flatulence.
c)Cureveda Sleep sure Tablet:- Contains valerian root extract for improved and healthy sleep.
By thereference of United States Patent Number: 10,357,530by Dr. Willmar Schwabe GmbH & Co. KG (Karlsruhe, DE) dated July 23, 2019, titled” Combination of valerian root extract and lavender oil for use in the treatment of sleep disorders”discloses The present invention relates to a combination of valerian root extract and lavender oil treating of sleep disorders, as well as to a combination of preparation comprising valerian root extract and lavender oil.
This invention provides a method for the treatment or prophylaxis of sleep disorders in a subject comprising administration to the subject of a combination comprising 250 to 500 mg of valerian root extract (extract of dried roots of Valeriana officinalis) and 40 to 80 mg of lavender oil (oil of flowers of Lavandula officinalis) per single dose. The valerian root extract is prepared by extraction with aqueous ethanol or aqueous methanol, wherein ethanol and water are used in a volume ratio of 30/70 to 90/10 or methanol and water are used in a volume ratio of 40/60 to 55/45 in the extraction. The sleep disorders are selected from disorders of initiating and maintaining sleep, circadian rhythm sleep disorders, sleep apnoea, nonorganic insomnia, nonorganic disorder of the circadian rhythm, sleepwalking (somnambulism), pavornocturnus, or nightmares (anxiety dreams).
By thereference of United States Patent Number: 6,544,565 by Ancile Pharmaceuticals, Inc. (San Diego, CA) dated April 8, 2003, titled” Use of Valeriana for the treatment of Restless Leg Syndrome and related disorders”discloses A method of inhibiting at least one symptomology of Restless Leg Syndrome (RLS) and its related disorders, including disorders such as periodic limb movements in sleep (PLMS) and periodic limb movement disorder (PLMD), is disclosed. The method optionally comprising identifying a host, afflicted with Restless Leg Syndrome (RLS) and its related disorders; and administering to the host a pharmaceutically effective amount of Valeriana. A novel method of inhibiting at least one symptomology of Restless Leg Syndrome (RLS) and its related disorders is disclosed. The method may also be used to treat a host in order to diminish undesired limb movements, and may involve the administration of a particular compound, found in the above-mentioned extracts, preferably selected from the group consisting of 10(14)-Aromadendren-4-ol, 6,10(14)-Guaiadien-4-ol, Valerenal, Valerenol, Valerenic acid, Acetoxyvalerenic acid, Hydroxyvalerenic acid, mimetics thereof, and may involve the administration of a combinations of these particular compounds and mimetics thereof.
The invention provides a method of treating the occurrence of at least one symptomology of at least one of the following disorders, Restless Leg Syndrome (RLS), periodic limb movements in sleep, periodic limb movement disorder, or the occurrence of unwanted limb movements, present in a host, comprising the step of: administering to the host a pharmaceutically effective amount of one or more compounds of Valeriana selected from the group consisting of 10(14)-Aromadendren-4-ol, 6,10(14)-Guaiadien-4-ol, Valerenal, Valerenol, Valerenic acid, Acetoxyvalerenic acid, Hydroxyvalerenic acid and combinations thereof.
The said compound is isolated from an extract of Valeriana officinalis.
By thereference of United States Patent Number 9,078,886by Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Shreveport, LA) dated July 14, 2015, titled” Compositions for the treatment of addiction, psychiatric disorders, and neurodegenerative disease”discloses The present invention features, inter alia, pharmaceutically acceptable compositions that include metyrapol as the sole pharmaceutically active agent; compositions that include metyrapol and at least one additional pharmaceutically active agent; compositions in which the agent targeting the HPA axis is, itself, new or modified (e.g., a bi-specific antibody designed to traverse the blood-brain barrier or a known compound redesigned by, for example, conjugation to a substance that traverses the blood-brain barrier); and compositions in which the agent targeting the HPA axis is newly formulated in such a way that it fails to significantly inhibit cortisol production in the adrenal gland. For example, the composition can be formulated to include a dosage that is too low to reduce plasma cortisol levels or formulated to preferentially affect the skin.
The pharmaceutical composition comprises a second pharmaceutically active agent which is selected from the group consisting of: a benzodiazepine, mirtazapine, atomoxetine, gabapentin, muscimol, baclofen, progabide, pregabalin, riluzole, vigabatrin, valproic acid, tiagabine, lamotrigine, phenytoin, carbamazepine, topiramate, a barbiturate, carisoprodol, chloral hydrate, glutethimide, L-theanine, kava, methaqualone, neuroactive steroids, z-drugs, propofol, scullcap, valerian, gamma-butyrolactone, gamma-hydroxybutyric acid, phenibut, deramciclane, hyperforin, gabaculine, phenelzine, valproate, vigabatrin, lemon balm (Melissa officinalis), GABA, L-glutamine, picamilon, and tetanospasmin.
By thereference of China patent application no. CN110013526 (A) by CHANGSHA SOFFIA CHUANGKE HEALTH MAN CO LTD dated 2019-05-13, titled” Massaging essential oil capable of improving sleep and use method of massaging essential oil”discloses The invention discloses massaging essential oil capable of improving sleep. The massaging essential oil capable of improving sleep comprises the following components in percentage by weight of 1-2% ofclary sage essential oil, 1-2% of melissa officinalis essential oil, 1-2% of rosewood essential oil, 1-2% of valerian essential oil, 0.5-1% of tea tree essential oil, 5-10% of wheat germ oil, 30-40%of grape seed oil and 45-58% of sweet almond oil. The massaging essential oil capable of improving sleep provided by the invention can effectively promote sleep, does not have any toxic or side effects on human bodies, and is convenient to use. The invention further provides a use method of the massaging essential oil capable of improving sleep.
By thereference of PCT application no. PCT/CN2016/099734by LIU JIAHUI [CN] dated 2016-09-22, titled” SKINCARE TEA AND PREPARATION METHOD THEREFOR”discloses A skincare tea, including camomile, floslonicerae, centellaasiatica, fructus momordicae, dried lemon, fructus jujubae, and melissa officinalis. The skincare tea adjusts a person's endocrine disorders from the inside, loosens the bowels and relieves constipation, and calms the nerves and aids sleep, in order to achieve a skincare effect. Also provided is a preparation method, including drying, sterilising, grinding, stirring, sterilising and six-step drying, as well as packaging. The method is simple and easy.
By thereference of PCT application no. PCT/CN2016/099735 by LIU JIAHUI [CN] dated 2016-09-22, titled” : SKINCARE TEA AND PREPARATION METHOD THEREFOR”discloses A skincare tea, including the following components: 2-7 parts of lavender, 2-8 parts of floslonicerae, 4-10 parts of bodhi seeds, 4-10 parts of fructus momordicae, 4-9 parts of dried lemon, 6-10 parts of fructus jujubae, and 3-7 parts of melissa officinalis. The skincare tea adjusts a person's endocrine disorders from the inside, loosens the bowels and relieves constipation, and calmsthe nerves and aids sleep, in order to achieve a skincare effect. Also provided is a preparation method, including drying, sterilising, grinding, stirring, sterilising and six-step drying, as well as packaging. The method is simple and easy.
By thereference of Bulgaria patent application no. BG2576 (U1)by SLAVCHEV KRASIMIR [BG]; KRALEV IVAN [BG] dated 2015-07-30, titled” HERBAL FOOD ADDITIVE”discloses The utility model relates to a herbal additive which is intended to supplement the normal diet and which is a concentrated source of substances with a nutritional and / or physiological effect. The food additive has the following composition: peppermint (Mentha pipegita L.) 30 mg, hawthorn (CrataegusMonogyna) 120 mg, valerian (Valeriana officinalis L.) 100 mg and lemon balm (Melissa officinalis) 10 mg. It is suitable for conditions of anxiety, tension and nervousness. The effects of the combination of peppermint, hawthorn, valerian, and balm are complementary. It has a beneficial effect on the nervous and cardiovascular system. The food additive contributes to a better sleep and mood, as well as the maintenance of mental balance and well-being.
By thereference of Japan patent application no. JP2010064969 (A) by EZAKI GLICO CO; OSAKA BIOSCIENCE INST dated 2008-09-09, titled” SEDATIVE AND SLEEP-IMPROVING AGENT”discloses This invention provides a sedative and to use it as a sleep-improving agent. The sedative comprises one or more as an active ingredients selected from the group consisting of (1) a dried essence of peppermint leaf, (2) Xylarianigripes, (3) Melissa officinalis, (4) essence of Hemerocallis fulva, (5) essence of green oat, (6) essence of rosebuds, (7) essence of Apocynumvenetum, (Yanron), (8) feverfew, (9) meadowsweet, (10) essence of chrysanthemum, (11) Siberian ginseng (Eleutherococcus), (12) lemon verbena, (13) Boswellia serrata, (14) enzyme-treated isoquercitrin, (15) an RNA derived from essence of beer yeast, (16) bamboo leaf, (17) essence of Sasaalbo-marginata and (18) apple-derived phloretin.
By thereference of China patent application no. CN110144637 (A) byZHONGKE TEXTILE RES INSTITUTE QINGDAO CO LTD dated 2019-04-22, titled”Fiber of valeriana officinalis composite polyester fiber carrier and preparation method of fiber”discloses The invention provides a preparation method of fiber of a valeriana officinalis composite polyester fiber carrier. The preparation method comprises steps as follows: pretreatment of a valeriana officinalis extract, preparation of a microcapsule solution and melt spinning. The fiber of the valeriana officinalis composite polyester fiber carrier has micropores on the surface, dissipation of odorandsteam is facilitated, the moisture-absorbing and rapid-drying performance is excellent, the water absorption rate is 189%-191%, the drip diffusion time is 1.4-2.2 s, the wicking height is 108-112 mm,the water vapor transmission is 10,008-10,124 g/(m<2>.d), and the breaking strength is 2.88-3.11 cN/dtex. The fiber of the valeriana officinalis composite polyester fiber carrier has the functions ofshortening time of people for falling sleep and prolonging the deep sleep time.
By thereference of China patent application no. CN109924786A by GUANGZHOU ZHONGTIAN KANGSHUN BIOLOGICAL PHARMACEUTICAL CO LTD dated 2019-03-06, titled” Sleep-helping healthcare pillow and preparing method thereof”The invention relates to a sleep-helping healthcare pillow and a preparing method thereof. A pillow inner of the pillow contains 1-2 parts of origanum vulgare, 1-2 parts of valeriana officinalis and 1-2 parts of chamomile. The preparing method includes the steps of smashing dry plant ingredients into fine powder, adding the fine powder to a 15% microcrystalline cellulose solution to be evenly mixed, adding the mixture to a 15% gelatin solution to be evenly mixed, conducting granulating, conducting drying until the water content is 9% or below, and filling the pillow inner with dried granules to obtain the pillow. The pillow has the advantages that the three plant ingredients are used in cooperation for having synergistic hypnosis and nerve soothing effects; the pillow inner is prepared through granulating with gelatin as the adhesive and microcrystalline cellulose as the diluent, the sleep-helping ingredients are slowly, properly and lastingly released, the good sleep-helping effect isrealized, and the effect lasts for two years long; the original herbs as the pillow inner raw materials are environmentally friendly, natural and low in cost.
By thereference of PCT application no. PCT/IB2019/059354 by GIOVANNONE DANIELE [IT] dated 2019-10-31, titled” PHYTO-THERAPYC COMPOSITIONS USEFUL TO IMPROVE THE QUALITY OF SLEEP AND IN THE TREATMENT OF INSONNIA, ANXIETY AND DEPRESSION”discloses A food, food supplement or pharmaceutical composition made of purified L- theanine, saffron and Valeriana officinalis extract in defined proportion is useful to improve the quality of sleep and in the treatment of insomnia, anxiety and depression in adult humans.
By thereference of China patent application no.CN109010587 (A) by GUANGXI BINYANG ZIXIANGYUAN XIANG IND CO LTD; CHEN QIQING dated 2018-08-23, titled” GUANGXI BINYANG ZIXIANGYUAN XIANG IND CO LTD; CHEN QIQING”disclosesThe invention discloses a traditional Chinese medicinal incense for tranquillizing mind and preserving health. The traditional Chinese medicinal incense for tranquillizing mind and preserving health comprises, by weight, 10-20 parts of Tuber Fleeceflower Stem, 8-15 parts of spine date seeds, 5-15 parts of amber, 5-15 parts of Poriacocos, 5-15 parts of lily, 6-17 parts of Radix Polygalae, 5-18 parts of lavender, 5-15 parts of Poria cum LignoHospite, 6-15 parts of Valeriana officinalis L., 2-5 parts of rice wine, 2-6 parts of honey, 15-40 parts of botanic Indonesian sticky powder, 5-25 parts of Alseodaphnepetiolaris bark powder, 5-35 parts of plant white gum powder and 0.3-1 part of a mildew inhibitor. Above natural Chinese herbal medicines and the natural botanic sticky powder, which meet medicinal standards, are deeply fermented, and the obtained fermentation product is taken out, and is molded to produce the traditional Chinese medicinal incense. The traditional Chinese medicinal incense for tranquillizing mind and preserving health has a sweet, fragrant and strong intensive fragrance, and the emitted fragrance can be inhaled into a human body in a certain space in order to achieve the calming, mind-tranquilizing, fatigue-eliminating, pressure-alleviating and sleep-improving effects on human bodies.
By thereference of Russian patent no. RU2017101445 (A) by Dr. Willmar Schwabe Gmbh And Co. Kg dated 2015-06-10, titled” COMBINATION OF VALERIAN ROOT EXTRACT AND LAVENDER OIL FOR USE IN TREATMENT OF SLEEP DISORDERS”discloses The invention relates to the pharmaceutical industry, and in particular to a combination for oral administration in the treatment or prevention of sleep disorders. Combination containing an extract of dried valerian root (Valeriana officinalis) and lavender oil (Lavandula officinalis), in a weight ratio of 7:1 to 1:1, for oral administration in the treatment or prevention of sleep disorders, where the extract of dried medicinal valerian root is obtained by extraction with aqueous ethanol or aqueous methanol, wherein during extraction, ethanol and water are used in a volume ratio of 30/70 to 90/10 or methanol and water are used in a volume ratio of 40/60 to 55/45.The combination described above synergistically prolongs sleep.
By thereference of China patent application no.CN106538908 (A)by QIN LIMEI dated 2016-10-27, titled” Sleep improving grape drink and manufacture method thereof”discloses The present invention discloses sleep improving grape drink and a manufacture method thereof, and belongs to the technical field of food processing. The grape drink is prepared from the following raw materials: grapes, litchi, strawberries, flosalbiziae, folium artemisiaeargyi, valeriana officinalis, semen ziziphispinosae, Chinese wolfberry fruits, semen hyoscyami, caulis polygonimultiflori, semen boitae, xylitol, chitosan, pectinase and cellulase. The grape drink is simple in manufacture method and the fruits are rich in glucose, vitamins, minerals, folic acids, free amino acids and other nutrients, so that the grape drink is unique in mouthfeel and rich in nutrition, and improves sleep. The Chinese herbal medicines contain alkaloids and various amino acid compositions, and can play the effects of calming mind and soothing nerves, dispelling wind and dredging collaterals, etc. The xylitol is a natural and healthy sweetener, and suitable for different groups of people to eat, especially for the middle-aged and elderly people, obese patients and patients with diabetes. The grape drink is free of any chemical preservatives and good in antiseptic property, does not change the flavor, and is long in preservation time and worthy of promotion and application.
By thereference of China patent application no. CN105477340 (A)by HEBEI TIANTIAN DAIRY GROUP CO LTD dated 2015-12-16, titled” Health drink capable of improving sleep and preparation method of health drink”discloses The invention discloses a health drink capable of improving the sleep and a preparation method of the health drink. The health drink is prepared from the following raw materials: valeriana officinalis, crowndaisy chrysanthemum, poriacocos, herbarhodobryirosei, dregeayunnanensis, nigella damascene, cobaea scandens, calceolaria crenatiflora, Polygala tricornisGagnep.[P.floribundaDunn; P.congestaRehd.et Wils.;P.yunnaensisChodat], radix salviaemiltiorrhizae, cortex albiziae, asarumcaulescens maxim, bulbophyllumlevinei, radix scrophulariae, faber bauhinia branchlet root, vernoniacinerea, bigbractbulbophyllum, fermented soybean, stem of gordoneuryale, grass-leaved eria, snake melon, stem of Dendrobium densiflorumLindl ex Wall., EriacorneriReichb.f.[E.goldschmidtianaSchltr.;E.septemlamellaHayata], ginseng leaves and honey. The health drink has the beneficial effects that the health drink is mild in property, excellent in mouth taste, and suitable for people of all ages, can have the remarkable effects after short-term drinking, has the efficacies of calming themind and soothing the nerves, is prepared from pure natural Chinese herbal medicines which have the homology of medicine and food, is safe and free of toxic and side effects, easy and convenient to prepare, and is low in cost.
By thereference of US patent application no. US2004241255 (A1)by BRATTSTROEM AXELdated 2002-09-16, titled” Pharmaceutical composition containing valerina officinalis extract”discloses Sleep-induced apnea or hypopnea in human patients can be treated effectively by administering to such patients a composition consisting at least in part of constituents of Valeriana officinalis that are capable of being extracted by solvents.
By thereference of Mexico patent application no. MX2018000805 (A)by JONATHAN ABRAHAM GRIJALVA PALOS [MX] dated 2018-01-18, titled” COMPOSITION FOR CHEWING GUM COMPRISING VALERIANA OFFICINALIS, MELISSA OFFICINALIS, PASSIFLORA INCARNATA, CARALLUMA FIMBRIATA, ITS USE FOR THE CONTROL OF THE APPETITE AND ANXIETY.”discloses The present invention relates to a composition for chewing gum comprising Valeriana officinalis, Passifloraincarnata, Melissa officinalis, and an extract of Caralluma Fimbriata based on the total weight of the composition for chewing gum.
By thereference of BG2812 (U1)by MILUSHEV SVILEN [BG] dated 2017-09-05, titled”Anti-stress composition”discloses The utility model refers to a biologically active anti-stress composition in the form of capsules based on a combination of extracts of medicinal herbs (plants) with a full set of B vitamins and an amino acid component and finds application in herbal-prophylactic herbal products, food supplements for overall stimulation of the organism and rapid recovery from the harmful effects of the chronic stress. The anti-stress composition comprises Melissa officinalis, L-tryptophan, niacin, folic acid, vitamin B1, vitamin B2, vitamin B6, vitamin B12, pantothenic acid, biotin, for its content of Valeriana officinalis from 20 mg to 500 mg, Passiflora edulis from 80 mg to 400 mg, Melissa officinalis from 25 mg to 200 mg, Scutellariabaicalensis from15 mg to 300 mg, L-Tryptophan 60 mg, Hops (Humulus lupulus) from 10 mg to 200 mg, cohosh root extract from 5 mg to 100 mg, Filipendulaulmaria from 10 mg to 100 mg), Asian centime (Centellaasiatica) from 0.5 mg to 20 mg, Vitamin B3 (niacin) - 180 mg, Vitamin B6 (pantothenic acid) - 10 mg, Vitamin B6 - 10 mg, Vitamin B1 - 14 mg, Vitamin B2 - 16 mg, Vitamin B12 - 50 mg, Folic acid - 400 ?g, D-biotin - 500 ?g.
By thereference of PCT applicationno. PCT/EP2011/051604 by RITTINGHAUSEN REINER [DE] dated 2011-02-03, titled” COMPOSITION FOR THE TREATMENT AND PREVENTION OF ANXIETY DISORDERS AND DYSSOMNIA”discloses The invention relates to a plant-based composition for the treatment and/or prevention of anxiety disorders and dyssomnia. The composition comprises extracts, essences and/or plant extracts and/or plant parts from Lavandula angustifolia MiIl. (lavender), Humulus lupulus L. (hops), Melissa officinalis L. (balm), Passifloraincarnata L. (passion flower) and Valerianaofficinalisagg. (valerian).
By thereference of Russian patent no. RU2215536 (C2) by GULYJ SERGEJ IVANOVICH [UA] dated 1999-07-15, titled” BIOLOGICALLY ACTIVE FOOD SUPPLEMENT OF CURATIVE- -PROPHYLACTIC EFFECT ELICITING SEDATIVE The invention relates to biologically active supplement as species involving lavender flowers and herb Lavandula angustifolia, medicinal valerian rhizome with roots Valeriana officinalis, medicinal common balm (Melissa) leaves and flowers, hop cones Humuluslupulos and containing additionally components that are taken among heather herb Calluna vulgaris, sweet clover herb,Melilotus officinalis, water hoarhound herb Lycopuseuropaeus, peony rhizomes with roots Paeniaanomalia, motherwort herb Leonurus cardiaca and their combinations. Multiple-component biologically active supplement is prepared by mixing components that elicits cumulative properties. Mixture is packaged and capsulated. EFFECT: expanded spectrum and effectiveness of product effect, valuable medicinal properties of supplement. 31 cl, 7 tbl, 3 dwg
By thereference of EPO patent application no.ES2038081 (A1)by POZUELO HERGUIDO PALMIRA [ES] dated 1991-12-30, titled” Herbal, tranquiliser composition based on valerian - also containing lime, poppy passion flower, balm and orange decoction, valerian tincture, lavender oil and cannabis”discloses Process to make anxiolytic compositions based on valeriana starting with the following components: valeriana officinalis, between 1% and 1.4%; tiliaplatphyllos, between 0.8% and 0.95%; papverrhoeas, between 0.5% and 0.65%; passifloraincarnata, between 0.8% and 0.95%; Melissa officinalis, between 0.8% and 0.95%; citrus aurantium, between 0.8% and 0.95%; lavender spica, between 0.5% and 0.65%; distilled water, between 46% and 52%; dark brown sugar, between 38% and 44%; valeriana officinalis tincture, between 4.0% and 4.3%; essential lavender oil, between 0.005% and 0.015%; and 6D marijuana cannabis, between 0.05% and 0.15%; specifically from the first seven components comes a mixture in the distilled water that is decocted for five minutes, then left to stand for six hours and subsequently filtered. The valeriana tincture and brown sugar is then added, stirred in and then it is necessary to wait until they have completely dissolved.;Thecompsn. consists of 1-1.4% valeriana officinalis, 0.8-.095% large leaved lime, 0.5-0.65% corn poppy, 0.8-0.95% passion flower, 0.8-0.95% balm, 0.8-0.95% Seville orange, 0.5-0.65% lavendar, 46-52% distilled water, brown sugar 38-44%, 4.0-4.3% valerian tincture, 0.005-0.015% essential oil of lavendar, and 0.05-0.15% cannabis sativa 6D (hemp). The first 7 ingredients are subjected to decoction in distilled water for 5 mins. allowed to stand for 6 hours and filtered. The tincture of valerian and brown sugar are added and stirred until completely dissolved.;Process to make anxiolytic compositions based on valeriana starting with the following components: valeriana officinalis, between 1% and 1.4% tiliaplatphyllos, between 0.8% and 0.95% papverrhoeas, between 0.5% and 0.65% passifloraincarnata, between 0.8% and 0.95% Melissa officinalis, between 0.8% and 0.95% citrus aurantium, between 0.8% and 0.95% lavender spica, between 0.5% and 0.65% distilled water, between 46% and 52% dark brown sugar, between 38% and 44% valeriana officinalis tincture, between 4.0% and 4.3% essential lavender oil, between 0.005% and 0.015% and 6D marijuana cannabis, between 0.05% and 0.15% specifically from the first seven components comes a mixture in the distilled water that is decocted for five minutes, then left to stand for six hours and subsequently filtered. The valeriana tincture and brown sugar is then added, stirred in and then it is necessary to wait until they have completely dissolved.The composition consists of 1-1.4% valeriana officinalis, 0.8-.095% large leaved lime, 0.5-0.65% corn poppy, 0.8-0.95% passion flower, 0.8-0.95% balm, 0.8-0.95% Seville orange, 0.5-0.65% lavendar, 46-52% distilled water, brown sugar 38-44%, 4.0-4.3% valerian tincture, 0.005-0.015% essential oil of lavendar, and 0.05-0.15% cannabis sativa 6D (hemp). The first 7 ingredients are subjected to decoction in distilled water for 5 mins. allowed to stand for 6 hours and filtered. The tincture of valerian and brown sugar are added and stirred until completely dissolved.
By thereference of Indian patent application no.00929/KOL/2005by PULOK K MUKHERJEE; KFH NAZEER AHAMED; BISHNU PADA SAHA; SIMANTIKA ROY CHOWDHURY INDIAN NATIONAL OF INDIAN NATIONAL DRUG COMPANY PVT. LTD. dated 07/10/2005, titled” A PROCESS OF PREPARING HERBAL COMPOSITION FOR THE MANAGMENT OF INSOMNIA/STREES AND PRODUCT This invention relates to an anti-stress composition containing various medicinal herbs and this composition prepared by a process comprising the steps i) mixing about 20 to 35 weight parts of Nardostachysjatamansi, 40 to 50 weight parts of Nelumbo nucifera. 20 to 25 weight parts of Zingiber officinalis and 8 to 15 weight parts of Valerianawallichll ii) extracting the mixture with water or alcohol or mixture of water and alcohol in suitable ratio. This herbal composition may be useful for the management of insomnia/ stress.
By thereference of Indian patent application no.3718/CHE/2013 by TABLETS (INDIA) LIMITEDdated 22/08/2013, titled” POLYHERBAL SLEEP INDUCING COMPOSITION”discloses The present invention relates polyherbal sleep inducing composition comprising 70 to 75% of Valeriana officinalis, 15 to 20% of Passifloraincarnata, and 6 to 8% of Humulus lupulus. The present invention relates to polyherbal sleep inducing composition that induces and maintains sleep in humans. The present invention also relates to process for preparing the sleep-inducing composition and to method of promoting sleep. The sleep-inducing compositions according to the present invention exhibits improved characteristic such as effective induction and maintenance of sleep throughout the night without night awakenings, significant reduction in the morning hangover and day time drowsiness and prevention of habit-forming adverse effects.In addition, the present invention also related to a palatable polyherbal sleep inducing composition having improved sensory characteristics such as improved mouthfeel, taste and odour. The present invention also relates to process for preparing such composition.
An Improved good sleeping syrup formulation and composition process is without the following carcinogenic ingredients which having several disadvantages: -
EDTA:-It has been shown to enhance the dermal penetration of other ingredients contained in a product. Thus, cosmetic formulators must exercise caution when combining it with other ingredients potentially harmful if absorbed by the skin. Furthermore, some studies suggest that disodium EDTA is weakly mutagenic (probably due to the fact that it binds with metals required for healthy cell division.). The other point is that EDTA builds upcomplexes in the environment that are not biologically degradable.
Parabens (preservative):- The Cosmetics, Toiletries and Perfumery Association released a statement in response to the bad press parabens were receiving after a study by P.D. Darbre was published that suggested paraben usage could be connected to breast cancer. They declared: “Parabens are officially approved for use under the Cosmetics Directive (76/768/EEC), the European legislation that regulates all cosmetics and toiletries. We can reassure the public that all cosmetic and toiletry products containing parabens may continue to be used safely.” Despite this, many people still have doubts and the parabens get a very bad press. The claim “paraben free” becomes a real USP on the market. The EU Commission banned the use of five other parabens incosmetic products - Isopropylparaben, Isobutylparaben, Phenylparaben, Benzylparaben and Pentylparaben (See Commission Regulation (EU) No 358/2014) due to the lack of data necessary for reassessment. Products placed on the market after 30 October 2014 will have to befree from these substances.
Steriod :Steroid use is associated with several adverse effects, such as an increased risk of heart disease and liver toxicity and there is an increased risk of contamination and infection. Steroid use may cause infertility and baldness in men. Deepening voice, facial changes and hair growth, enlarged clitoris, irregular menstrual cycles, decreased breast size and infertility in women.
No added flavour
However, none of the above discussed inventions provides herbal formulation for relaxation and a process of preparing thereof containsValerian extract and Melissa leaf extracts.All the above discussed inventions are not providing such Herbal formulation for relieves restlessness, calms and relaxes and provides calm to the over-stimulated nervous system.
Objects of the invention:
The main object of the present invention is to provide Herbal formulation for relaxation and a process of preparing containsValeriana officinalis and Melissa officinalis.
Another object of the present invention is to provide herbal formulation for relaxation and a process of preparing,wherein Valerian extract provide relieves restlessness, calms and relaxes.
Another object of the present invention is to provide Herbal formulation for relaxation and a process of preparing, whereinMelissa leaf extracts used to calm the over-stimulated nervous system.
Yet another object of the present invention is to provide Herbal formulation for relaxation and a process of preparing makes easy to fall asleep and the body can relax.
Summary of the invention:
An Herbal formulation for relaxation and a process of preparingcomprises ingredient of Tagar Root extract (Valeriana officinalis); Lemon Balm leaf extract (Melissa officinalis); Purified water; Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerin; Citric Acid.The Herbal formulation relieves restlessness, calms and relaxes and also provide calm to the over-stimulated nervous system.The herbal formulation for relaxation and a process of preparing thereof comprises steps of:taking purified water and boiling it, cooling boiled water till 70oC, adding the components of Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerinone, one after the other under stirring; homogenizing for 10 minutes;adding the components of Tagar Root extract and Lemon Balm leaf Extract under stirring and homogenizing; finally checking the pH and adjusting it between 5.5-6.0 with the help of citric acid solution to obtain the final product.
Statement of the invention:
A herbal formulation for relaxation and a process of preparing thereof, comprising Tagar Root extract (Valeriana officinalis); Lemon Balm leaf Extract (Melissa officinalis); Purified water; Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerin; Citric Acid, all the ingredients working synergistically, wherein said formulation relieves restlessness, calms and relaxes and used to calm the over-stimulated nervous system; said Tagar Root extract (Valeriana officinalis) is in the range of 0.06 percent to 1.1 percent; said Lemon Balm leaf Extract (Melissa officinalis) is in the range of 0.05 percent to 1.3 percent; Wherein Potassium Sorbate is in the range of 0.01 to 0.3 percent; Wherein Sodium Benzoate is in the range of 0.02 to 0.35 percent; Wherein Xanthan Gum is in the range of 0.02 to 0.52 percent; Wherein said process of preparing the formulation comprises the steps of: taking purified water and boiling it, cooling boiled water till 70oC, adding the components of Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerinone, one after the other under stirring; homogenizing for 10 minutes;adding the components of Tagar Root extract and Lemon Balm leaf Extract under stirring and homogenizing; finally checking the pH and adjusting it between 5.5-6.0 with the help of citric acid solution to obtain the final product.
Brief description of invention:
The present invention will now be described herein after with reference to the accompanying drawings, in which some, but not all embodiments of the invention are shown. While the following description details the preferred embodiments of the present invention is not limited in its application to the details of construction and arrangement of the parts illustrated in the accompanying drawings.With reference to the figures, the enclosed description and drawings are merely illustrative of preferred embodiments and represent several different ways of configuring the present invention. Although specific components, materials, configurations and uses of the present invention are illustrated and set forth in this disclosure, it should be understood that a number of variations to the components and to the configuration of those components described herein and in the accompanying figures can be made without changing the scope and function of the invention set forth herein.
The present invention is proposed a herbal formulation for relaxation and a process of preparingcomprising Tagar Root extract (Valeriana officinalis); Lemon Balm leaf Extract (Melissa officinalis); Purified water; Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerin; Citric Acid, all the ingredients working synergistically, wherein said formulation relieves restlessness, calms and relaxes and used to calm the over-stimulated nervous system.
The herbal formulation for relaxation and a process of preparing comprises following steps:taking purified water and boiling it, cooling boiled water till 70oC, adding the components of Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerinone, one after the other under stirring; homogenizing for 10 minutes;adding the components of Tagar Root extract and Lemon Balm leaf Extract under stirring and homogenizing; finally checking the pH and adjusting it between 5.5-6.0 with the help of citric acid solution to obtain the final product.
The present invention comprising means Tagar Root extract (Valeriana officinalis)fromQty. in %0.06 to Qty. in %1.1 and exact amount of Qty. in % 0.5.
The present invention comprising means Lemon Balm leaf Extract (Melissa officinalis)from Qty. in % 0.05 to Qty. in % 1.3 and exact amount of Qty. in % 0.25.
The present invention comprising means Purified water form Qty. in % QS to Qty. in % QS and exact amount of Qty. in % QS.
The present invention comprising means Potassium Sorbate from Qty. in % 0.01 to Qty. in % 0.3 and exact amount of Qty. in % 0.15.
The present invention comprising means Sodium Benzoate form Qty. in % 0.02 to Qty. in %0.35 and exact amount of Qty. in % 0.15.
The present invention comprising means Trehalosefrom Qty. in % 0.1 to Qty. in %4 and exact amount of Qty. in % 1.0.
The present invention comprising means Mannitol from Qty. in % 0.2 to Qty. in % 5 and exact amount of Qty. in % 1.0.
The present invention comprising means Sorbitol 70% from Qty. in % 1to Qty. in % 9 and exact amount of Qty. in % 5.0.
The present invention comprising means Xanthan Gum from Qty. in % 0.02 to Qty. in % 0.52 and exact amount of Qty. in % 0.2.
The present invention comprising means Sodium Saccharin from Qty. in %0.01 to Qty. in % 1.0 and exact amount of Qty. in % 0.05.
The present invention comprising means Glycerin from Qty. in % 0.7 to Qty. in % 12 and exact amount of Qty. in % 5.0.
The present invention comprising means Citric Acid from Qty. in % 0.003 to Qty. in % 0.1 and exact amount of Qty. in % 0.05.
All these ingredients are mentioned in Table 1.
Table 1
S.No. Ingredients Botanical Name From to
Qty. in % Qty. in %
1 Tagar Root extract Valeriana officinalis 0.06 1.1
2 Lemon Balm leaf Extract Melissa officinalis 0.05 1.3
3 Purified water QS QS
4 Potassium Sorbate 0.01 0.3
5 Sodium Benzoate 0.02 0.35
6 Trehalose 0.1 4
7 Mannitol 0.2 5
8 Sorbitol 70% 1 9
9 Xanthan Gum 0.02 0.52
10 Sodium Saccharin 0.01 1.0
11 Glycerin 0.7 12
12 Citric Acid 0.003 0.1

Table 2 represents the exact amount of the ingredients used in the formulation and composition.
Table 2:
S.No. Ingredients Botanical Name Qty. in %
1 Tagar Root extract Valeriana officinalis 0.5
2 Lemon Balm leaf Extract Melissa officinalis 0.25
3 Purified water QS
4 Potassium Sorbate 0.15
5 Sodium Benzoate 0.15
6 Trehalose 1.0
7 Mannitol 1.0
8 Sorbitol 70% 5.0
9 Xanthan Gum 0.2
10 Sodium Saccharin 0.05
11 Glycerin 5.0
12 Citric Acid 0.05
In embodiment of the present invention provides herbal formulation for relaxation and a process of preparing thereofcomprising Tagar Root extract (Valeriana officinalis); Lemon Balm leaf Extract (Melissa officinalis); Purified water; Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerin; Citric Acid, all the ingredients working synergistically, wherein said formulation relieves restlessness, calms and relaxes and used to calm the over-stimulated nervous system.
In another embodiment of the present invention provides herbal formulationwhich relieves restlessness, calms and relaxes and used to calm the over-stimulated nervous system. The syrup makes easy to fall asleep and the body can relax.
In another embodiment of the present invention provides Tagar Root extract (Valeriana officinalis) from Qty. in % 0.06 to Qty. in % 1.1 and exact amount of Qty. in % 0.5.
In another embodiment of the present invention provides Lemon Balm leaf Extract (Melissa officinalis) from Qty. in % 0.05to Qty. in % 1.3 and exact amount of Qty. in % 0.25.
In another embodiment of the present invention provides Purified water form Qty. in % QS to Qty. in % QS and exact amount of Qty. in % QS.
In another embodiment of the present invention provides Potassium Sorbate from Qty. in % 0.01 to Qty. in % 0.3 and exact amount of Qty. in % 0.15.
In another embodiment of the present invention provides Sodium Benzoate form Qty. in % 0.02 to Qty. in % 0.35 and exact amount of Qty. in % 0.15.
In another embodiment of the present invention provides Trehalose from Qty. in % 0.1 to Qty. in % 4 and exact amount of Qty. in % 1.0.
In another embodiment of the present invention provides Mannitol from Qty. in % 0.2 to Qty. in % 5 and exact amount of Qty. in % 1.0.
In another embodiment of the present invention provides Sorbitol 70% from Qty. in % 1to Qty. in % 9 and exact amount of Qty. in % 5.0.
In another embodiment of the present invention provides Xanthan Gum from Qty. in % 0.02 to Qty. in % 0.52 and exact amount of Qty. in % 0.2.
In another embodiment of the present invention provides Sodium Saccharin from Qty. in % 0.01 to Qty. in % 1.0 and exact amount of Qty. in % 0.05.
In another embodiment of the present invention provides Glycerin from Qty. in % 0.7 to Qty. in % 12 and exact amount of Qty. in % 5.0.
In another embodiment of the present invention provides Citric Acid from Qty. in % 0.003 to Qty. in % 0.1 and exact amount of Qty. in % 0.05.
In yet another embodiment, the present invention provides herbal formulation for relaxation and a process of preparingthe formulation comprises the steps of: taking purified water and boiling it, cooling boiled water till 70oC, adding the components of Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerinone, one after the other under stirring; homogenizing for 10 minutes;adding the components of Tagar Root extract and Lemon Balm leaf Extract under stirring and homogenizing; finally checking the pH and adjusting it between 5.5-6.0 with the help of citric acid solution to obtain the final product.

Claims:We claim:
1. A herbal formulation for relaxation and a process of preparing thereof, comprising Tagar Root extract (Valeriana officinalis); Lemon Balm leaf Extract (Melissa officinalis); Purified water; Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerin; Citric Acid, all the ingredients working synergistically, wherein said formulation relieves restlessness, calms and relaxes and used to calm the over-stimulated nervous system.
2. The herbal formulation as claimed in claim 1, wherein said Tagar Root extract (Valeriana officinalis) is in the range of 0.06 percent to 1.1 percent.
3. The herbal formulation as claimed in claim 1, wherein said Lemon Balm leaf Extract (Melissa officinalis) is in the range of 0.05 percent to 1.3 percent.
4. The herbal formulation as claimed in claim 1, wherein Potassium Sorbate is in the range of 0.01 to 0.3 percent.
5. The herbal formulation as claimed in claim 1, wherein Sodium Benzoate is in the range of 0.02 to 0.35 percent.
6. The herbal formulation as claimed in claim 1, wherein Xanthan Gum is in the range of 0.02 to 0.52 percent.
7. The herbal formulation as claimed in claim 1, wherein said process of preparing the formulation comprises the steps of: taking purified water and boiling it, cooling boiled water till 70oC, adding the components of Potassium Sorbate; Sodium Benzoate; Trehalose; Mannitol; Sorbitol 70%; Xanthan Gum; Sodium Saccharin; Glycerinone, one after the other under stirring; homogenizing for 10 minutes;adding the components of Tagar Root extract and Lemon Balm leaf Extract under stirring and homogenizing; finally checking the pH and adjusting it between 5.5-6.0 with the help of citric acid solution to obtain the final product.