The present invention relates to the field of herbal medicinal compositions. More particularly,
the invention relates to a herbal formulation for curing sleep apnea and obstructive sleep apnea.
BACKGROUND OF THE INVENTION
Sleep Apnea is a very well-known sleep disturbance problem leading to other health problems
resulting in prolonged sleep disturbance and deprivation. Sleep Apnea is marked by pauses in
breathing (or shallow breaths) while sleeping. Sleep apnea may be obstructive sleep apnea,
central sleep apnea or mixed/complex sleep apnea. In people with obstructive sleep apnea (the
most common form of sleep apnea), airflow to the lungs is blocked because the airway
collapses or is obstructed during sleep. Central sleep apnea (CSA) occurs when the brain does
not send signals to the body to breathe regularly during sleep, causing breaks in breathing.3
This can also manifest as very shallow breathing. Mixed or complex sleep apnea includes
symptoms of both obstructive sleep apnea and central sleep apnea. The sufferers of sleep apnea
may also experience obesity, snoring, nausea, tiredness, daytime sleepiness, depression,
hypertension, dementia, hyperactivity, menopause etc. The most common type of sleep apnea
is obstructive sleep apnea which is seen in maximum sufferers.
Adam Benjafield et al. in his study (Lancet Respir Med 2019, Published Online July 9, 2019),
estimated that 936 million (95% CI 903–970) adults aged 30–69 years (men and women) have
mild to severe obstructive sleep apnea and 425 million (399–450) adults aged 30–69 years have
moderate to severe obstructive sleep apnea globally. As per said study, the number of affected
individuals was highest in China, followed by the USA, Brazil, and India. The problem is also
persistent in children and people living in urban cities.
Several machines help obstructive sleep apnea patients to sleep normally, but they do not
provide significant relief or cure to the problem. Instead, they are majorly related to treatment
of one or more of the symptoms of sleep apnea. The known treatments for sleep apnea include
use of implants such as hypoglossal nerve stimulator, surgical procedures such as somnoplasty,
tonsillectomy, Mandibular/maxillary advancement surgery etc. or mechanical therapy by use
of devices like positive air pressure devices, facial interfaces, adaptive servo-ventilation
instruments, oxygen concentrators and oral appliances. However, these treatments are just
supportive care methods, or may be invasive methods with one or more side effects.
3
Few formulations are known in the prior art for treating one or more problems associated with
sleep apnea. Allopathic compositions known in the art suffer from various side-effects.
WO2013173317A1 discloses methods, kits, and compositions for treating obstructive sleep
apnea with one or more α2-adrenergic agonist (e.g., dexmedetomidine). KR20200115598A
provides compositions and methods for treating sleep apnea comprising administering a
pharmaceutical composition comprising (R)-oxybutynin and norepinephrine reuptake inhibitor
(NRI) and (R)-oxybutynin and norepinephrine reuptake inhibitor (NRI).
CN102091195B discloses a medicament for treating snore and sleep apnea syndrome
comprising 4-8 parts of liquorice, 10-20 parts of crude white atractylodes rhizome, 25-35 parts
of rhizoma alismatis, 25-35 parts of tuckahoe, 10-20 parts of red sage root, 7-13 parts of radix
linderae, 25-35 parts of oyster, 25-35 parts of clematis root and 25-35 parts of radix platycodi.
CN108853323A discloses a traditional Chinese medicinal composition for treating adenoid
hypertrophy accompanied by nasal congestion, snoring, open-mouth breathing, obstructive
sleep apnea and palatal tonsil enlargement. The composition comprises of 2 to 8 parts of
scorpio, 5 to 15 parts of bombyx batryticatus, 5 to 15 parts of bulbus fritillariae thunbergii, 10
to 20 parts of radix scrophulariae, 10 to 20 parts of radix paeoniae rubra, 2 to 14 parts of radix
platycodonis, 2 to 10 parts of tangerine peel, 2 to 10 parts of rhizoma pinelliae praeparata, 5 to
15 parts of poria cocos, and 1 to 5 parts of crude liquorice root.
Many herbal plant extracts and compositions are known in the art for treating one or more
symptoms associated with sleep apnea. However, these compositions treat only few symptoms
and do not cure the condition completely. Thus, there is a significant need for plant-based
compositions that can provide long lasting cure for sleep apnea and associated problems
without any serious side-effects. The present invention provides a solution to the problem of
the prior art by providing a herbal composition comprising natural ingredients in a defined
percentage range, which act together synergistically to provide a long term relief to sleep apnea
with reduced chances of relapse.
OBJECTS OF THE INVENTION
An important object of the present invention is to provide a herbal composition for long lasting
treatment of sleep apnea with no side-effects.
4
Another object of the present invention is to provide a method for preparation of said herbal
composition for treatment of sleep apnea.
A further object of the present invention is to provide a method of treatment comprising
administration of said herbal composition to a subject suffering from sleep apnea in a defined
dosage.
BRIEF DESCRIPTION OF TABLES
The accompanying figures illustrate some of the embodiments of the present invention and,
together with the descriptions, serve to explain the invention. These figures have been provided
by way of illustration and not by way of limitation.
Table 1 provides percentage range of the herbal powder composition.
Table 2 lists down some exemplary compositions for treating sleep apnea.
Tables 3-13 illustrates test results of the composition on different subjects of varying age
groups.
Table 14 provides details of differential composition with varied percentage of components.
Table 15 shows differential compositions with absence of one or more components.
SUMMARY OF THE INVENTION
The present invention primarily provides a composition for treating sleep apnea. The
composition comprises various plant parts in defined percentage range. More particularly, the
composition comprises Jufa flower (Hyssopus officinalis), Gaojaban flower (Borago
officinalis), Gaojaban leaves, Khatmi seeds (Althaea officinalis), Billilotan whole plant
(Melissa parviflora), Kaddu kernel cake (Cucurbita maxima), Badam kernel cake (Prunus
amygdalus), Lasoda fruit (Cordia latifolia), Behidana seeds (Pyrus cydonia) and Mulethi root
(Glycyrrhiza glabra).
The present invention further provides a method of the present invention involving mixing one
or more plant parts selected from flowers, fruits, leaves, seeds, roots, kernels or whole plant, in
dried and powdered form wherein the oil of kaddu kernels and badam kernels is extracted
separately through a cold press machine and the remainder residue is extracted which is called
as cake. The cake is grounded and dried to powder form. All other eight ingredients of the
composition are taken separately in dried powder form and mixed to obtain a powdered
composition. The ingredients are mixed together to form a uniform mixture.
5
The herbal composition of the present invention provides relief in anxiety, flatulence in
stomach, dyspepsia, disturbance in sleep, hoarseness, palpitation, discomfort in urination,
excessive thirst, laryngitis, congestion of lungs, headache (heavy head feeling), snoring, dry
throat, nasal obstruction, choking while asleep, breathing, dry mouth, blood pressure, excessive
day time sleepiness etc. Besides this, the composition of the present invention was also found
to help in weight loss, promotes normal urination and improves digestion
DETAILED DESCRIPTION OF INVENTION
The details of one or more embodiments of the invention are set forth in the accompanying
description below including specific details of the best mode contemplated by the inventors for
carrying out the invention, by way of example. It will be apparent to one skilled in the art that
the present invention may be practiced without limitation to these specific details.
The use of “comprise”, “comprises”, “comprising”, “contain”, “contains”, “containing”,
“include”, “includes”, and “including” are not intended to be limiting. It is to be understood
that both the foregoing general description and this detailed description are exemplary and
explanatory only and are not restrictive.
Unless otherwise defined, scientific and technical terms used herein shall have the meanings
that are commonly understood by those of ordinary skill in the art. Further, unless otherwise
required by context, singular terms shall include pluralities and plural terms shall include the
singular.
The foregoing broadly outlines the features and technical advantages of the present disclosure
in order that the detailed description of the disclosure that follows may be better understood. It
should be appreciated by those skilled in the art that the conception and specific embodiment
disclosed may be readily utilized as a basis for modifying the disclosed methods or for carrying
out the same purposes of the present disclosure.
The present invention provides to a herbal composition for providing long lasting cure to both
sleep apnea. More particularly, the herbal composition of the present invention comprises of
Jufa flower (Hyssopus officinalis), Gaojaban flower (Borago officinalis), Gaojaban leaves,
Khatmi seeds (Althaea officinalis), Billilotan whole plant (Melissa parviflora), Kaddu kernel
cake (Cucurbita maxima), Badam kernel cake (Prunus amygdalus), Lasoda fruit (Cordia
6
latifolia), Behidana seeds (Pyrus cydonia) and Mulethi root (Glycyrrhiza glabra) in a defined
percentage range as mentioned under Table 1 below:
Table 1: Percentage Range of the Herbal powder composition
Common Name Botanical Name Ranges
Jufa flower Hyssopus officinalis 1 to 15%
Gaojaban flower Borago officinalis 1 to 20%
Gaojaban leaves Borago officinalis 1 to 35%
Khatmi seeds Althaea officinalis 1 to 35%
Billilotan whole plant Melissa parviflora 1 to 35%
Kaddu kernel cake Cucurbita maxima 1 to 40%
Badam kernel cake Prunus amygdalus 1 to 40%
Lasoda fruit Cordia latifolia 1 to 40%
Behidana seeds Pyrus cydonia 1 to 40%
Mulethi root Glycyrrhiza glabra 1 to 20%
In an embodiment, the components of the present invention are such that Jufa flower (Hyssopus
officinalis) is preferably in the range of 3-5% in wt., Gaojaban flower (Borago officinalis) is
preferably in the range of 3.4-7% in wt., Gaojaban leaves (Borago officinalis) is preferably in
the range of 7-11% in wt., Khatmi seeds (Althaea officinalis) is preferably in the range of 7-
11% in wt., Billilotan whole plant (Melissa parviflora) is preferably in the range of 7-11% in
wt., Kaddu kernel cake (Cucurbita maxima) is preferably in the range of 17-20% in wt., Badam
kernel cake (Prunus amygdalus) is preferably in the range of 17-20% in wt., Lasoda fruit
(Cordia latifolia) is preferably in the range of 8-12% in wt., Behidana seeds (Pyrus cydonia)
is preferably in the range of 3-12% in wt., Mulethi root (Glycyrrhiza glabra) is preferably in
the range of 2.6-5.6% in wt.
In an embodiment of the present invention, the method of preparation of the herbal composition
involved mixing one or more plant parts selected from flowers, fruits, leaves, seeds, roots,
kernels or whole plant, in dried and powdered form wherein the oil of kaddu kernels and badam
kernels is extracted separately through a cold press machine and the remainder residue is
extracted which is called as cake. The cake is grounded and dried to powder form. All other
7
eight ingredients of the composition are taken separately in dried powder form and mixed to
obtain a powdered composition. The ingredients are mixed together to form a uniform mixture.
In an embodiment, the composition is a solid or liquid preparation.
The composition of the present composition is formulated for oral administration and may be
administered in the form of a in the form of a powder, capsule, tablet, syrup, pill, lozenge or
any other form suitable for oral administration based on consumer preference.
The composition of the present invention may be administered orally approximately 5 grams
twice a day.
In another embodiment, the solid or liquid preparation of the present invention may optionally
comprise an acceptable carrier or excipient. The carriers or excipient may be selected from the
group consisting of a binder, a filler, a preservative, a capsule shell, a diluent, a lubricant, a
disintegrant, flavoring or wetting agent.
In another embodiment, the composition provides relief from anxiety, flatulence in stomach,
dyspepsia, disturbance in sleep, hoarseness, palpitation, discomfort in urination, excessive
thirst, laryngitis, congestion of lungs, headache (heavy head feeling), snoring, dry throat, nasal
obstruction, choking while asleep, breathing, dry mouth, blood pressure and excessive day time
sleepiness.
In still another embodiment, the composition unexpectedly also helps in reducing weight,
promotes normal urination and improves digestion.
In a further embodiment, the present invention provides a method of treating a subject suffering
from sleep apnea comprising administering the herbal composition of the present invention to
the subject having any one or more of the symptoms selected from anxiety, flatulence in
stomach, dyspepsia, disturbance in sleep, hoarseness, palpitation, discomfort in urination,
excessive thirst, laryngitis, congestion of lungs, headache (heavy head feeling), snoring, dry
throat, nasal obstruction, choking while asleep, breathlessness, dry mouth, high blood pressure,
excessive day time sleepiness, obesity and indigestion.
8
EXAMPLES
The following examples particularly describe the manner in which the invention is to be
performed. But the embodiments disclosed herein do not limit the scope of the invention in any
manner.
Example 1: Preparation of the Herbal Composition
Required plant parts such as flowers, fruits, leaves, seeds, roots, whole plant were collected.
The plant parts were cleaned thoroughly by washing to remove unwanted contaminants and
dried at room temperature.
Washed and dried Jufa flower (Hyssopus officinalis), Gaojaban flower (Borago officinalis),
Gaojaban leaves, Khatmi seeds (Althaea officinalis), Billilotan whole plant (Melissa
parviflora), Lasoda fruit (Cordia latifolia), Behidana seeds (Pyrus cydonia) and Mulethi root
(Glycyrrhiza glabra) were ground into a powder separately.
The oil of kaddu kernels and badam kernels was extracted separately through a cold press
machine and the remainder residue after extraction was obtained as a cake. The cake was then
dried and grounded to powder form.
The ground plant parts in the form of fine powder were mixed together uniformly to obtain the
powdered composition of the present invention. Some exemplary compositions of the present
invention are listed under Table 2.
Table 2: Some exemplary compositions for treating sleep apnea
Components
Exemplary Formulations
I II III IV V VI VII
Jufa flower
(Hyssopus
officinalis)
5.0% 5.0% 4.0% 3.6% 4.8% 3.6% 3.0%
Gaojaban
flower
(Borago
officinalis)
5.0% 7.0% 7.0% 5.4% 4.0% 3.4% 5.0%
Gaojaban
leaves
(Borago
officinalis)
7.0% 11.0% 10.0% 9.1% 9.5% 11.0% 10.5%
9
Khatmi seeds
(Althaea
officinalis)
11.0% 7.0% 9.8% 9.1% 11.0% 8.9% 10.0%
Billilotan
whole plant
(Melissa
parviflora)
11.0% 11.0% 7.0% 9.0% 9.0% 8.0% 11.0%
Kaddu kernel
cake
(Cucurbita
maxima)
17.0% 17.9% 19.0% 18.1% 19.5% 20.0% 20.1%
Badam
kernel cake
(Prunus
amygdalus)
19.0% 18.0% 17.0% 18.1% 18.1% 19.5% 20.1%
Lasoda fruit
(Cordia
latifolia)
11.0% 10.0% 11.0% 12.0% 12.0% 8.0% 12.0%
Behidana
seeds
(Pyrus
cydonia)
11.4% 10.0% 11.0% 12.0% 8.0% 12.0% 3.0%
Mulethi root
(Glycyrrhiza
glabra)
2.6% 3.1% 4.2% 3.6% 4.1% 5.6% 5.3%
Example 2: Testing in vivo efficacy of the herbal composition
The exemplary compositions of the present invention were administered to different subjects
of varying age groups including men, women and children. The composition was orally
administered in the form of a powder along with water twice daily.
i) Adult Male Subjects Tested
61 Male subjects were chosen for the study. The herbal composition of the present invention
was administered at different dosages over varying time periods as follows:
Test Group A
Table 3
Number
of
Subjects
Age
Group
(in
yrs)
Symptom/
condition
Dosage
(twice a
day)
Term of
administration
Effect/Symptom(s)
relieved
10
5 30-40 Ordinary
Sleep
Apnea
2-3g 1 month Got some relief but
amount of relief reduced
with a gap of 15 days
5g 2 months Started showing
improvements slowly and
got 90% relief in 3 months
Test Group B
Table 4
Number
of
Subjects
Age
Group
(in yrs)
Symptom/
condition
Dosage
(twice a day)
Term of
administra
tion
Effect/
Symptom(s)
relieved
4 30-40 Overweight,
Indigestion
problems; Felt
excessive
sleepiness in
daytime, Abrupt
awakening during
night by gasping
or choking and
Dry mouth
4g 1 month Got some relief in
snoring and
indigestion.
Increased to
5g
3 months Significant relief
in snoring.
Test Group C
Table 5
Number
of
Subjects
Age
Group
(in yrs)
Symptom/
condition
Dosage
(twice a day)
Term of
administra
tion
Effect/
Symptom(s)
relieved
8 30-40 Nasal obstruction,
dyspepsia,
Lethargic feeling
and snoring right
after falling
asleep.
5g 5 month Got significant
relief in snoring.
Test Group D
Table 6
Number
of
Subjects
Age
Group
(in yrs)
Symptom/
condition
Dosage
(twice a day)
Term of
administra
tion
Effect/
Symptom(s)
relieved
11
6 40-45 Fatty liver, felt
breathlessness
while walking,
Constipation, Dry
mouth and dry
throat during
sleep and used to
wake up because
of thirst, felt
stressed.
4g 2 month Got relief in
symptoms and felt
better.
After 2
months
dosage
increased to
5g
3 months Got relief in dry
throat and
significant relief
in snoring.
Test Group E
Table 7
Number
of
Subjects
Age
Group
(in
yrs)
Symptom/
condition
Dosage
(twice a
day)
Term of
administration
Effect/Symptom(s)
relieved
4 40-45 Had Swelling all
over the body, felt
lazy most of the
time, feeling of
depression and
lack of appetite,
waking up during
sleep all of a
sudden, Had
feeling of choked
throat, Sleeping
while sitting in
bed during night.
3g 1.5 months Got some relief in
swelling and stress.
Increased
dose to 4
grams
4 months Started having
uninterrupted sleep
without snoring and
stopped waking up
during sleep and
95% relief in
snoring.
Test Group F
Table 8
Number
of
Subjects
Age
Group
(in
yrs)
Symptom/
condition
Dosage
(twice a
day)
Term of
administration
Effect/Symptom(s)
relieved
2 40-45 Felt sleepy during
the day, had lack
of concentration,
headache in the
morning,
Suffocation during
sleep at night,
2g 1 month Got some relief
Increased
the
dosage to
4g
3 months Got significant
relief in snoring,
restlessness and
blood pressure
became normal.
12
High blood
pressure.
Test Group G
Table 9
Number
of
Subjects
Age
Group
(in
yrs)
Symptom/
condition
Dosage
(twice a
day)
Term of
administration
Effect/Symptom(s)
relieved
32 45-70 Incomplete sleep,
stressed, smokers,
overweight, were
using two pillows,
indigestion issues,
had feeling of
heaviness in head,
waking up all of a
sudden during
sleep, fear of
death, had
obstructed nose
5g 3 months Got relief 80% in 3
months and nasal
passages started
opening up; Relief
in stress and lost
weight also
Same
dosage
continued
2 months Got 90% cured
ii) Adult Female Subjects Tested
40 Female subjects were chosen for the study. The herbal composition of the present invention
was administered at different dosages over varying time periods as follows:
Test Group H
Table 10
Number
of
Subjects
Age
Group
(in
yrs)
Symptom/
condition
Dosage
(twice a
day)
Term of
administration
Effect/Symptom(s)
relieved
15 30-40 Irritation,
frequent
urination during
night, frequent
thirst,
hypothyroidism,
difficulty in
breathing,
headache,
diabetics, loud
3g 2 months Got some relief in
snoring
Increased
to 5g
3 months Slowly the
symptoms got
better and
significant relief
was found for
snoring
13
snoring and
acidity
Test Group I
Table 11
Number
of
Subjects
Age
Group
(in
yrs)
Symptom/
condition
Dosage
(twice a
day)
Term of
administration
Effect/Symptom(s)
relieved
25 40-65 Nasal
obstruction,
oedema, high
blood pressure,
feelings of
suffocation,
mental stress,
fearful feelings,
sense of
tiredness
weakness of
brain,
hoarseness in
throat
3g 1 month Some relief was
achieved in some
patients but not in all.
Increased
to 4g
2months Patients felt better.
Got 70% relief.
Further
Increased
to 5g
2 months Got significant relief
in the 5th month.
iii) Minor Subjects Tested
15 Children were chosen for the study. The herbal composition of the present invention was
administered at different dosages over varying time periods as follows:
Test Group J
Table 12
Number
of
Subjects
Age
Group
(in
yrs)
Symptom/
condition
Dosage
(twice a
day)
Term of
administration
Effect/Symptom(s)
relieved
15 7-12 Sinus issues,
disturbed sleep,
obstruction in air
flow, laziness
and lethargic,
1.5g 15 days Some relief after 15
days.
14
sluggish
digestion,
tonsilitis,
adenoid,
swelling in nose
and throat,
overweight
Increased
to 2g
after 15
days
3-4 months Significant relief
The results for patients suffering from different symptoms and conditions associated with sleep
apnea and of different age groups showed that the composition was really efficient in providing
about 90-95% relief after a dosage of 3-5gms twice daily for about 2-5 months.
Example 3: Differential composition and their effects/side effects
To check the optimum range of ingredients, the inventors prepared several test compositions
to check the efficacy of the herbal composition of the present invention. The percentage range
of different components were varied and tested to check the efficacy of the final composition.
Table 13: Differential Composition with varied percentage of components
Table 3: Differential
compositions with
varied percentage of
components
Components of the Herbal Composition and their
Amount (in % by wt.)
Side Effects
Jufa flower
Gaojaban flower
Gaojaban leaves
Khatmi seeds
Billilotan whole
plant
Kaddu kernel cake
Badam kernel cake
Lasoda fruit
Behidana seeds
Mulethi root
I 6 5 46 7 5 6 6 7 7 5
Nausea,
stomachache
II 2 5 7 5 7 8 8 5 8 45
Laziness,
headache,
diarrhea,
leukorrhea
III 45 3 7 6 9 8 6 6 6 4
Swelling,
diarrhea
IV 4 5 3 4 4 5 60 5 5 5
Night fall,
leukorrhea,
constipation
V 2 5 9 49 9 9 5 5 4 3 Constipation
VI 3 6 6 7 48 5 8 5 9 3
Headache,
dry cough
15
VII 3 2 8 5 5 55 5 5 8 4
Liver
dysfunction,
bloating
VIII 4 4 4 4 5 10 10 51 5 3
Excess
urination,
liver
dysfunction
IX 5 3 5 9 7 6 7 8 48 2 Constipation
X 4 44 5 7 6 8 8 9 6 3
Nausea,
giddiness
Percentage range of different components of the composition was changed beyond the defined
optimum range and tested to check for any effects/ side-effects. Differing compositions, I to X
were found to cause one or more side effects, supporting the inventive activity and synergistic
effect of the components of the claimed composition in the defined range.
Inventors of the present invention also carried out experimentation to test and validate the
synergistic activity of the components in the claimed composition. Different compositions were
prepared where one or more components were missing. However, said compositions did not
show the desired effect equivalent to the herbal composition of the present invention.
Table 14: Differential compositions with absence of one or more components Differential Compositions
Components of the Herbal Composition
Jufa flower
Gaojaban flower
Gaojaban leaves
Khatmi seeds
Billilotan whole plant
Kaddu kernel cake
Badam kernel cake
Lasoda fruit
Behidana seeds
Mulethi root
C1 ✓ ✓ ✓ ✓      ✓
C2  ✓ ✓       
C3       ✓ ✓ ✓ 
C4   ✓       ✓
C5 ✓       ✓  
C6      ✓    ✓
C7 ✓   ✓     ✓ 
C8       ✓ ✓  
16
The Differential compositions C1-C8 resulted in relief in one or more symptoms of sleep apnea
condition but does not provide significant relief or alleviation of all symptoms. The
results/effect below table shows the relief of symptoms using compositions of Table 3.
Table 15: Symptoms relieved with Differential Compositions C1-C8
Composition Symptoms relieved
C1 Asthma, hoarseness, laryngitis, constipation, anxiety, wheezing cough
C2 Congestion of lungs, excessive thirst, gastritis, palpitation
C3 Cough, diarrhea, constipation
C4 Sore throat, constipation, painful urination, acid reflux
C5 Anxiety, cough, dyspepsia, heart burn, smoother breathing
C6 Oedema, constipation
C7 Anxiety, cough, sore throat
C8 Sexual debility, diarrhea, cough, painful urination
ADVANTAGES
1. Plant based composition without any side effects.
2. Provides long-lasting relief from sleep apnea.
3. Easy and simple method of preparation.
4. Easily palatable.
5. Provided unexpected advantageous effect in terms of weight loss, improved digestion and
normal urination.

We Claim:
1. A herbal composition for treatment of sleep apnea comprising:
i. Jufa flower (Hyssopus officinalis) is in the range of 1 to 15% by wt.;
ii. Gaojaban flower (Borago officinalis) is in the range of 1 to 20% by wt.;
iii. Gaojaban leaves (Borago officinalis) is in the range of 1 to 35% by wt.;
iv. Khatmi seeds (Althaea officinalis) is in the range of 1 to 35% by wt.;
v. Billilotan whole plant (Melissa parviflora) is in the range of 1 to 35% by wt.;
vi. Kaddu kernel cake (Cucurbita maxima) is in the range of 1 to 40% by wt.;
vii. Badam kernel cake (Prunus amygdalus) is in the range of 1 to 40% by wt.;
viii. Lasoda fruit (Cordia latifolia) is the range of 1 to 40% by wt.;
ix. Behidana seeds (Pyrus cydonia) is in the range of 1 to 40% by wt.; and
x. Mulethi root (Glycyrrhiza glabra) is in the range of 1 to 20% by wt.
2. The composition as claimed in claim 1, comprising Jufa flower (Hyssopus officinalis)
preferably in the range of 3-5% in wt., Gaojaban flower (Borago officinalis) preferably
in the range of 3.4-7% in wt., Gaojaban leaves (Borago officinalis) preferably in the
range of 7-11% in wt., Khatmi seeds (Althaea officinalis) preferably in the range of 7-
11% in wt., Billilotan whole plant (Melissa parviflora) preferably in the range of 7-
11% in wt., Kaddu kernel cake (Cucurbita maxima) preferably in the range of 17-20%
in wt., Badam kernel cake (Prunus amygdalus) preferably in the range of 17-20% in
wt., Lasoda fruit (Cordia latifolia) preferably in the range of 8-12% in wt., Behidana
seeds (Pyrus cydonia) preferably in the range of 3-12% in wt., and Mulethi root
(Glycyrrhiza glabra) preferably in the range of 2.6-5.6% in wt.
3. The composition as claimed in claim 1, wherein the composition is orally administered
in an amount of 2-5 grams, twice a day to a subject.
4. A composition as claimed in claim 1, wherein the composition can be administered in
the form of a powder, capsule, tablet, syrup, concentrate, pill, lozenge, granule or any
other form suitable for oral administration.
5. A composition as claimed in claim 1, wherein sleep apnea may be obstructive sleep
apnea, central sleep apnea or mixed/complex sleep apnea.
6. A composition as claimed in claim 1, as and when used for preparing a medicament for
treating sleep apnea.
7. A method of preparing a herbal composition as claimed in claim 1, comprising
a) Collecting one or more plant parts selected from flowers, fruits, leaves, seeds,
roots, kernels or whole plant, wherein the plant parts are selected from Jufa
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flower (Hyssopus officinalis), Gaojaban flower (Borago officinalis), Gaojaban
leaves, Khatmi seeds (Althaea officinalis), Billilotan whole plant (Melissa
parviflora), Lasoda fruit (Cordia latifolia), Behidana seeds (Pyrus cydonia),
Mulethi root (Glycyrrhiza glabra), kaddu kernels (Cucurbita maxima) and
badam kernels (Prunus amygdalus);
b) washing the plant parts obtained in step a) to remove unwanted contaminants
and drying the same at room temperature;
c) grinding each of the dried components namely Jufa flower (Hyssopus
officinalis), Gaojaban flower (Borago officinalis), Gaojaban leaves, Khatmi
seeds (Althaea officinalis), Billilotan whole plant (Melissa parviflora), Lasoda
fruit (Cordia latifolia), Behidana seeds (Pyrus cydonia) and Mulethi root
(Glycyrrhiza glabra) into a powder separately;
d) extracting the oil of kaddu kernels and badam kernels separately through a cold
press machine to obtain the remainder residue as a cake;
e) drying the cake obtained in step d) and grinding to a powder form; and
f) mixing the ground plant parts obtained in step c) with powder obtained in step
e) to obtain a powdered composition.
8. A method of treating a subject suffering from sleep apnea comprising administering the
herbal composition as claimed in claim 1 to the subject having any one or more of the
symptoms selected from anxiety, flatulence in stomach, dyspepsia, disturbance in sleep,
hoarseness, palpitation, discomfort in urination, excessive thirst, laryngitis, congestion
of lungs, headache (heavy head feeling), snoring, dry throat, nasal obstruction, choking
while asleep, breathlessness, dry mouth, high blood pressure, excessive day time
sleepiness, obesity and indigestion.x