Claims:I/We, Claim,
1. A nutraceutical formulation comprising of the combination of extracts from the following herbs:
a. Mucuna pruriens
b. Ashwagandha
c. Tribulus terrestris
d. L.arginine and
e. Chlorophytum borivilianum
2. A nutraceutical herbal formulation as claimed in claim 1 effectively treats male infertility and improves the reproductive health in men.
3. A nutraceutical formulation as claimed in claim 1 is a health supplement in an ingestible form.
4. The health supplement as claimed in claim 2 comprising the nutraceutical composition claimed in claim 1; wherein the ingestible form is selected from a powder, capsule, tablet, syrup, granules, gel, spray or beverage.

, Description:1. PREAMBLE TO THE DESCRIPTION
The following complete specification particularly describes the invention and the manner in which it is to be performed:
“HERBAL FORMULATION TO IMPROVE REPRODUCTIVE HEALTH IN MEN”
2. TECHNICAL FIELD
2. The present invention relates to the field of herbal formulation and composition; more particularly health and wellness supplements. The present invention improves reproductive health in men”
3.2. BACKGROUND OF THE INVENTION
3. The use of dietary supplements has increased dramatically as our knowledge about the role of nutrients and other bioactive components of food in health has increased. Although much of the information about the diet and health connection that has driven this trend is related to the reduction of chronic disease risk in adults, belief in the prophylactic use of dietary intervention including the use of dietary supplements has been extended to consumers throughout the life cycle.
1. In Ancient days, people maintained their health through proper diet practices and herbs formed an integral part of their healthcare system. Herbalism was most popular in Asian Region whereas India has been popular for herbs and herbal healthcare system since time immemorial.
2. The present invention aims to give a dietary supplement which helps to improve the fertility factors, through the phytochemicals present in the herbal extracts which acts as antioxidant agents that suppresses the oxidative damage and in turn maintaining overall sexual health.
3. Infertility is “a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse” – as per WHO
4. Causes of male infertility
1. Effective production of sperm
2. Sperm count, or the number of sperm
3. Shape of the sperm
4. Movement of the sperm.
5. Erectile dysfunction
5. Risk factors of infertility
• Age
• Smoking
• High alcohol consumption
• Being overweight or obese
• Exposure to toxins, such as pesticides, herbicides, and heavy metals.
6. In addition to different physical defects, oligospermia is the widespread cause of male infertility in more than 90% of the cases. Out of these, about 30 to 40% causes are unexplained, and in the rest of the cases, critical illness, genetic abnormalities, malnutrition, pollution, side effects of some medicines, hormones, and chemicals play a key role in infertility.
7. Erectile dysfunction is an inability to achieve a normal sexual intercourse including premature ejaculation, retrograded, retarded or inhibited ejaculation, erectile dysfunction, arousal difficulties, compulsive sexual behavior, orgasmic disorder and failure of detumescence.
In our country with the ancient practice of Ayurveda, some of the medicinal plants have proven to possess a scientifically proven aphrodisiac that can enhance and help to increase the intensity of sex in men
15. To improve the reproductive health in men the herbs Velvet bean (Mucuna pruriens), Ashwagandha (Withania somnifera), Gokshur (Tribulus terrestris), L-Arginine, and Safed Musli (Chlorophytum borivillianum) are used to form this formulation.

3.3 PRIOR ART
16. WO2008113118A1- Herbal compositions and methods for treating male infertility and/or sub fertility, and/or for treating or alleviating a symptom or condition accompanying male infertility or sub fertility. A composition for prophylactic or therapeutic treatment of male infertility and/or subfertility, comprising the herbs:
Tu Si Zi Semen cuscatae
5 Fu Pen Zi Fructus Rubi chingii
He Shou Wu Radix Polygoni mxύtiflori
Sheng Di Radix Rehmanniae glutinosae
Gou Qi Zi Fructus Lycii chinensis
Shan Zhu Yu Fructus Corni officinalis
10 Mu Dan Pi. Cortex Moutan radicis
Dang S hen Radix Codonopsis pύ'ulosae
Dan Shen Radix Salviae mϊltiorrhizae
Hong Hua Carthamiflos
201911024420- AN ANTI-INFERTILITY FORMULATION FOR MALES AND PROCESS OF PREPARATION THEREOF
The present disclosure relates to the field of ayurvedic medicinal formulations. In particular, the present disclosure provides an anti-infertility formulation for males and process of preparation thereof.
wherein the formulation per 1000 gm comprises: (a) Syzygium aromaticum about 22gm; (b) Poppy about 22gm; (c) Valeriana wallichi about 22gm; (d) Woodfordia fruticosa about 22gm (e) Elwendia persica about 22gm; (f) Cuminum cyminum about 22gm; (g) Elettaria cardamomum about 22gm; (h) Plantago major about 22gm; (i) Cinnamomum verum about 22gm; (j) Mesua ferrea about 22gm; (k) Piper longum about 22gm; (l) Zingiber officinale about 22gm; (m) Myristica fragrans Houtt about 22gm; (n) Bambusa arundinacea about 22gm; (o) Emblica officinalis about 22gm; (p) Terminalia chebula about 22gm; (q) Terminalia bellirica about 22gm; (r) Withania somnifera about 100gm; (s) Mucuna pruriens about 100gm; (t) Cymbopogon citratus about 48gm; (u) Cinnamomum camphora about 22gm; (v) Piper cubeba about 22gm; and (w) rock sugar about 333 gm.
201721007662- HERBAL COMPOSITIONS AND PROCESS TO TREAT INFERTILITY IN MEN
Infertility and reproduction associated disorders are on the rise and millions of people spend billions to tackle the said infirmities. On the other hand, most of the allopathic medicines and treatments are not free from adverse side-effects further alleviating the troubles of the patients. Thus, simple, cost-effective and no-side effect based formulations for tackling infertility in humans are the need of the day. Disclosed herein is synergistic herbal composition and process for production of such a composition which can improve sexual well-being of an individual and which may also support the physical and physiological ability of an individual.
Ingredients Parts of plant used Percentage Used (w/w) Solvent / Mode of Preparation
Mucuna pruriens Seed <25% Dry powder
Anacyclus pyrethrum Root <15% Dry powder
Tabasheer - < 15% Dry powder
Rock Sugar - <15% Dry Powder
Pistacia lentiscus Resin <15% Dry powder
Piper longum Fruit <15% Dry powder
CN101468098 - MIAO MEDICINE FORMULA FOR TREATING STERILITY OR BARRENNESS OF MAN AND WOMEN
The invention relates to a Miao medicine formula for treating female and male infertility using Chinese herbal medicine as raw material, composed of angelica, chuanxiong rhizome, dahurian angelica, Zhaxin, safflower, natural coppe, rehmannia root, Qianxinzhi, Sichuan aconite root, wild aconite root, cassia twig, glycyrrhiza, eucommia, joepye weed, notoginseng, white peony root, prepared rehmannia root, radix codonopsis pilosulae, white atractylodes rhizome, amomum fruit, nutagrass flatsedge rhizome, gloosy ganoderma and ginger, therefore two Miao medicine formulas for treating female and male infertility are prepared. The Miao medicine formula for treating female and male infertility can make up the shortage of traditional Chinese medicine for treating female and male infertility very well and has very high curative effect for treating female and male infertility due to male sperm-production dysfunction and female no-ovulation and abnormal menstruation. The male formula is prepared to be medicinal wine and the female formula is prepared to be medicinal broth.
CN107375700A- COMPOUND HERBAL PREPARATION FOR PREVENTING AND TREATING MALE INFERTILITY
The invention provides a compound herbal preparation for preventing and treating male infertility. The compound herbal preparation is prepared by leaching and extracting the following materials through ethanol, methanol, acetone and water: root of trias verrucosa, seeds of Anders hygrophila salicifolia, seeds of mucuna prur, seeds of mimosa pudica, acacia senegal gum, astragalus root, seed coat of semen plantaginis, kapok gum and eurycoma longifolia root. Based upon human tests, it is proved that with the application of the compound herbal preparation, health level of a patient with the male infertility can be effectively improved, a semen volume, a sperm density and a sperm activity level can be improved, and male testicular hormone and hormone level can be obviously increased; therefore, the compound herbal preparation has a potential value of being developed into medicines or related food for treating the male infertility.
CN106456691A - COMPOSITION FOR PREVENTING AND TREATING MALE INFERTILITY, CONTAINING MIXED HERBAL EXTRACT AS ACTIVE INGREDIENT AND USE
The invention relates to a composition and health functional food for preventing and treating male infertility using a mixed herbal mixture. Through an in vitro sperm mobility promotion effect evaluation method experiment (for investigating effects of an herbal extract of Morinda officinalis, Cuscuta seed, and/or Allium cepa of the invention on changes in sperm count and mobility in human semen.
A health supplement food for preventing or ameliorating male infertility comprising a mixed herbal extract of Morinda officinalis, dodder seed and onion bulbs as a main ingredient.
4. TECHNICAL PROBLEM TO BE SOLVED
Infertility is “a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse” – as per WHO. In addition to different physical defects, oligospermia is the widespread cause of male infertility in more than 90% of the cases. The present invention has a beneficial effect on infertility aspects of men. These herbs tend to possess antioxidant phytochemicals which scavenges free radicals and reactive oxygen species responsible for the infertility issues in men. The present embodiment is found to be very effective in reducing the risk of reactive oxygen species that can damage the sperm in two ways: damage the sperm membrane which could decrease the mobility and possibility of connecting to the oocyte or can damage the genetic material of the sperm. The present embodiment is target specific and improves reproductive health in men.
5. SUMMARY OF THE INVENTION
18. The following summary is provided to facilitate an understanding of some of the innovative features unique to the disclosed embodiment and is not intended to be a full description. A full appreciation of the various aspects of the embodiment disclosed herein can be gained by taking the entire specification, claims and abstract as a whole.
19. The prior arts are insufficiently suited for effective treatment of male infertility. It is, therefore, one aspect of the present invention to provide a novel herbal formulation that improves reproductive health in men.
20. The main aspect of the present invention is to provide for a supplement to reduce the conditions of infertility in men.
21. It is another aspect of the present invention to provide a formulation having the property of aphrodisiac activity used to improve the sperm count with the help of herbal ingredients.
22. It is another aspect of the present invention is to produce a novel herbal formulation to balance hormone and boost testosterone levels.
23. Yet another aspect of the present invention is it helps in increasing strength and endurance power in men.
24. Yet another aspect of the present invention is it is used to energize, strengthen and eventually enhance sexual ability of men.
25. Still another aspect of the present invention is used as an anti-
oxidant, anti-microbial and immune-modulatory supplement.
27. The aforementioned aspects and other objectives can be achieved by combining the extracts of the following five herbs in an appropriate proportion as described in the detailed description.
1. Velvet bean (Mucuna pruriens)
2. Ashwagandha (Withania somnifera)
3. Gokshur (Tribulus terrestris)
4. L-Arginine and
5. Safed Musli (Chlorophytum borivillianum)
7. DETAILED DESCRIPTION
28. The present invention provides for herbal extract which has the ability to treat infertility with a combination of Velvet bean (Mucuna pruriens), Ashwagandha (Withania somnifera), Goskshur (Tribulus terrestris), L-Arginine and Safed Musli (Chlorophytum borivillianum).
Velvet bean (MUCUNA PRURIENS)
29. Botanical Description: Velvet bean is an annual, climbing shrub with long vines that can reach over 15 m. Leaves are trifoliate, gray-silky beneath; petioles are long and silky, 6-11 cm. Leaflets are membranous, terminal leaflets are smaller, lateral very unequal sided. Dark purple flowers (6 to 30) occur in drooping racemes. Fruits are curved, 4-6 seeded. The longitudinally ribbed pod, is densely covered with loose orange hairs which cause a severe itch if they come in contact with skin. The beans are shiny black or brown. It is found in tropical Africa, India and the Caribbean. In India, it is found in the Himalayas, at altitudes of 150-1200 m, and Western Ghats.
30. Phytoconstituents: The seeds of velvet beans are known to produce the unusual nonprotein amino acid 3-(3,4- dihydroxyphenyl)-l-alanine (L-DOPA). It also contains glutathione, gallic acid and beta-sitosterol. It also has unidentified bases such as mucunine, mucunadine, prurienine and prureininine. The seed also contains two tetrahydroquinoline alkaloids namely: 3-methoxy-1,1-dimethyl-6,7-dihydroxy-1,2,3.4- tetrahydroquinoline and 3-methoxy-1, 1-dimethyl-7,8- dihydroxy-1,2,3.4-tetrahydroquinoline
31. The major biological properties of Mucuna pruriens
a) The active ingredient L-DOPA stimulates the hypothalamus and forebrain, thus stimulating the secretion of Gondatrophin Releasing Hormone (GnRH), which ultimately activates anterior lobe of pituitary to secrete FSH and LH. Elevated levels of FSH and LH stimulate the process of spermatogenesis via testosterone.
b) Mucuna pruriens seed powder is rich in antioxidants which helps to enhance reproductive function.
c) It also improves semen quality and testicular cytoarchitectural integrity.
d) Possess antioxidant, anti-inflammatory, neuroprotective, and antibacterial properties.
ASHWAGANDHA (WITHANIA SOMNIFERA)
32. Botanical Description: Ashwagandha, is native to drier parts of India. It is a perennial herb that reaches about 6 feet in nature. It is a short, tender perennial herb growing 35-75 cm tall. Velvet-hairy branches extend radially from a central stem. Leaves are dull green, elliptic, usually up to 10-12 cm long. The flowers are small, green and bell-shaped. Orange fruits in persistent papery sepals follow the small greenish flowers. Ashwagandha is propagated by division, cuttings or seed. Seed is the best way to propagate them.
33. Phytoconstituents: The major phytoconstituents are withaferin A and withanolide D, Anaferine (alkaloid), anahygrine (alkaloid), beta-sisterol, chlorogenic acid (in leaf only), cysteine (in fruit), cuscohygrine (alkaloid), iron, pseudotropine (alkaloid), scopoletin, somniferinine (alkaloid), somniferiene (alkaloid), tropanol (alkaloid), withanine (alkaloid), withananine (alkaloid) and withanolides A-Y(steroidal lactones), somniferine, somnine, pseudo-withanine, tropine, pseudo-tropine, 3-a-gloyloxytropane, cuscohygrine, isopelletierine, anahydrine, sitoindoside VII and sitoindoside VIII, pseudo-withanine, tropino, choline, cuscohygrine, isolettetierine, anahydrine, 3-alpha-gloyloxy tropane.
34. The major biological properties of Ashwagandha
a) Ashwagandha helps to increase the sperm concentration, semen volume and sperm motility.
b) Ashwagandha also helps to improve serum testosterone and luteinizing hormone levels.
c) Help to modify and regulate hormone production and flow.
d) Reducing energy loss, general fatigue and exhaustion.
e) Improving vitality, sexual performance and fertility in men.
f) Acts as an antioxidant and boost immunity.

GOKSHUR (TRIBULUS TERRESTRIS)
35. Botanical Description: Puncture Vine is a tap rooted herbaceous perennial plant that grows as a summer annual in colder climates. The stems radiate from the crown to a diameter of about 10 cm to over 1 m, often branching. They are usually prostrate, forming flat patches, though they may grow more upwards in shade or among taller plants. The leaves are pinnately compound with leaflets less than a quarter-inch long. The flowers are 4-10 mm wide, with five lemon-yellow petals. A week after each flower blooms, it is followed by a fruit that easily falls apart into four or five single-seeded nutlets. The nutlets or "seeds" are hard and bear two sharp spines, 10 mm long and 4-6 mm broad point-to-point. These nutlets strikingly resemble goats' or bulls' heads; the "horns" are sharp enough to puncture bicycle tyres and to cause considerable pain to unshod feet.
36. Phytoconstituents: The main chemical constituents of this plant are flavonoids, alkaloids, saponins, lignin, amides and glycosides.
The major properties of Gokshur (Tribulus terrestris)
a) The major compound present in the plant is protodiosine, this substance increases the number and motility of the sperm.
b) Protodiosine also increases the level of testosterone and dihydrotestosterone.
c) It increases the level of luteinizing hormone and testosterone and converts testosterone to dihydrotestosterone which in addition to increasing libido, improves muscle development, and produces red blood cells.
d) Diuretic and herbal tonic for genito-urinary system
e) Aphrodisiac, anti-urolithic, immune-modulatory activity
f) Also have an anti-inflammatory, analgesic, antispasmodic, and antibacterial activities
L-ARGININE
37. L-arginine (2-Amino-5-guanidinopentanoic acid) is synthesized in different chemical pathways in the body. L-arginine participates different metabolic pathways in various tissues in animal cells and present in the structure of the various proteins and biomolecules.
38. It causes increased libido and erection by increasing blood flow in genital area.
39. L-arginine is known to increase sperm motility due to adenosine triphosphate (ATP) synthesis.
40. L-arginine which provides protection against oxidative stress which is likely to act as an antioxidant.
41. L-arginine plays a key role in modulating the host’s defense and cellular immunity.
SAFED MUSLI (CHLOROPHYTUM BORIVILLIANUM)
42. Botanical Description: The species name comes from a suburb in Mumbai called Borivili. Safed Musli is an herb with sub-erect leaves and tuberous root system. It can grow up to a maximum height of 1.5 ft. Tubers can grow up to a depth of 10". The plant sports a rosette of long, slender leaves, growing from a thick, fleshy rhizome. The flowers are small, white, produced on sparse panicles. Leaves are slightly yellowish and white flowers with 6 petals are arranged on the flowering stalk which emerge from the centre of the plant. The seed is very small, black and enclosed in the holes. In one hole, there are about 10-12 seeds.
43. Phytoconstituents: Alkaloids, tannins, phenols, glycosides and steroids are the major phytoconstituents present in the Chlorophytum borivillianum plant
44. The major biological properties of Chlorophytum borivillianum
a) Aphrodisiac activity – The plant helps to improve sperm count, increased aphrodisiac action, increased libido, sexual vigor, and sexual arousal.
b) Immuno-modulatory activity
c) Anthelmintic activity
d) Antioxidant activity
e) Antiulcer activity
f) Anti-stress activity
g) Anti-tumor and antimutagenic activity
h) Anti-microbial activity
COMPOSITION OF THE FORMULATION
45. The present embodiment consists of Velvet beans (Mucuna pruriens), Ashwagandha (Withania somnifera), Gokshur (Tribulus terrestris), Safed Musli (Chlorophytum borivillianum) and an amino acid, L-Arginine which produced a significant result for treating infertility. These ingredients work through various mechanisms to improve the male sexual function, sperm count, motility, through improving the levels of hormones such as luteinizing hormones, follicle stimulating hormone and testosterone levels.