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Heteroaryl Derivatives As Parp Inhibitors

Abstract: Disclosed are compounds of formula (I) their tautomeric forms stereoisomers and pharmaceutically acceptable salts thereof wherein ring Ar ring B R1 R5 X Y p q r and s are as defined in the specification pharmaceutical compositions including a compound tautomer stereoisomer or salt thereof and methods of treating or preventing diseases or disorders for example cancer that are amenable to treatment or prevention by inhibiting the PARP enzyme of a subject.

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Patent Information

Application #
Filing Date
13 January 2018
Publication Number
17/2018
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

LUPIN LIMITED
Kalpataru Inspire 3rd Floor Off Western Express Highway Santacruz (East) Maharashtra Mumbai 400 055

Inventors

1. KARCHE Navnath Popat
Lupin Limited (Research Park) 46A / 47A Nande Village Taluka Mulshi Maharashtra Pune 412 115
2. TILEKAR Ajay Ramchandra
Lupin Limited (Research Park) 46A / 47A Nande Village Taluka Mulshi Maharashtra Pune 412 115
3. KURHADE Sanjay Pralhad
Lupin Limited (Research Park) 46A / 47A Nande Village Taluka Mulshi Maharashtra Pune 412 115
4. JADHAV Ganesh Rajaram
Lupin Limited (Research Park) 46A / 47A Nande Village Taluka Mulshi Maharashtra Pune 412 115
5. GUPTA Nishant Ramniwasji
Lupin Limited (Research Park) 46A / 47A Nande Village Taluka Mulshi Maharashtra Pune 412 115
6. SINHA Neelima
Lupin Limited (Research Park) 46A / 47A Nande Village Taluka Mulshi Maharashtra Pune 412 115
7. PALLE Venkata P.
Lupin Limited (Research Park) 46A / 47A Nande Village Taluka Mulshi Maharashtra Pune 412 115
8. KAMBOJ Rajender Kumar
Lupin Limited (Research Park) 46A / 47A Nande Village Taluka Mulshi Maharashtra Pune 412 115

Specification

Documents