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"Il 1 Binding Proteins"
Abstract: The present invention encompasses IL-1α binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Antibodies of the invention have high affinity for IL-1α and neutralize IL-1α activity. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting IL-1α and for inhibiting IL-1α activity, e.g., in a human subject suffering from a disorder in which IL-1α activity is detrimental.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
08 July 2011
Publication Number
35/2013
Publication Type
INA
Invention Field
TRADITIONAL KNOWLEDGE BIOTECHNOLOGY
Status
Email
Parent Application
Applicants
ABBOTT LABORATORIES
100 ABBOTT PARK ROAD, ABBOTT PARK, IL 60064, USA.
Inventors
1. HSIEH CHUNG-MING
22 OLDE FIELD ROAD NEWTON, MASSACHUSETTS 02459, USA
2. WU CHENGBIN
386 PROSPECT STREET SHREWSBURY, MASSACHUSETTS 01545, USA.
Specification
NA
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 5281-DELNP-2011-AbandonedLetter.pdf | 2018-02-05 |
| 1 | 5281-delnp-2011-Form-3-(09-01-2012).pdf | 2012-01-09 |
| 2 | 5281-delnp-2011-Correspondence Others-(09-01-2012).pdf | 2012-01-09 |
| 2 | 5281-DELNP-2011-FER.pdf | 2017-07-28 |
| 3 | 5281-delnp-2011-GPA.pdf | 2012-03-03 |
| 3 | 5281-delnp-2011-Assignment-(13-08-2013).pdf | 2013-08-13 |
| 4 | 5281-delnp-2011-Form-5.pdf | 2012-03-03 |
| 4 | 5281-delnp-2011-Correspondence-Others-(13-08-2013).pdf | 2013-08-13 |
| 5 | 5281-delnp-2011-Form-3.pdf | 2012-03-03 |
| 5 | 5281-delnp-2011-Form-2-(13-08-2013).pdf | 2013-08-13 |
| 6 | 5281-delnp-2011-GPA-(13-08-2013).pdf | 2013-08-13 |
| 6 | 5281-delnp-2011-Form-1.pdf | 2012-03-03 |
| 7 | 5281-delnp-2011-Description (Complete).pdf | 2012-03-03 |
| 7 | 5281-delnp-2011-Correspondence Others-(16-05-2013).pdf | 2013-05-16 |
| 8 | 5281-delnp-2011-Correspondence Others.pdf | 2012-03-03 |
| 8 | 5281-delnp-2011-Abstract.pdf | 2012-03-03 |
| 9 | 5281-delnp-2011-Assignment.pdf | 2012-03-03 |
| 9 | 5281-delnp-2011-Claims.pdf | 2012-03-03 |
| 10 | 5281-delnp-2011-Assignment.pdf | 2012-03-03 |
| 10 | 5281-delnp-2011-Claims.pdf | 2012-03-03 |
| 11 | 5281-delnp-2011-Abstract.pdf | 2012-03-03 |
| 11 | 5281-delnp-2011-Correspondence Others.pdf | 2012-03-03 |
| 12 | 5281-delnp-2011-Correspondence Others-(16-05-2013).pdf | 2013-05-16 |
| 12 | 5281-delnp-2011-Description (Complete).pdf | 2012-03-03 |
| 13 | 5281-delnp-2011-Form-1.pdf | 2012-03-03 |
| 13 | 5281-delnp-2011-GPA-(13-08-2013).pdf | 2013-08-13 |
| 14 | 5281-delnp-2011-Form-2-(13-08-2013).pdf | 2013-08-13 |
| 14 | 5281-delnp-2011-Form-3.pdf | 2012-03-03 |
| 15 | 5281-delnp-2011-Correspondence-Others-(13-08-2013).pdf | 2013-08-13 |
| 15 | 5281-delnp-2011-Form-5.pdf | 2012-03-03 |
| 16 | 5281-delnp-2011-Assignment-(13-08-2013).pdf | 2013-08-13 |
| 16 | 5281-delnp-2011-GPA.pdf | 2012-03-03 |
| 17 | 5281-delnp-2011-Correspondence Others-(09-01-2012).pdf | 2012-01-09 |
| 17 | 5281-DELNP-2011-FER.pdf | 2017-07-28 |
| 18 | 5281-delnp-2011-Form-3-(09-01-2012).pdf | 2012-01-09 |
| 18 | 5281-DELNP-2011-AbandonedLetter.pdf | 2018-02-05 |
Search Strategy
| 1 | bindingprotein_28-07-2017.pdf |