Sign In to Follow Application
View All Documents & Correspondence
View All Documents & Correspondence
Improved Process For The Preparation Of Fluticasone Propionate
Abstract: The present invention relates to an improved process for the preparation of Fluticasone propionate.The present invention particularly related to the use of lithium halide reagent in the preparation of intermediate of formula III. The present invention also relates to the purification of fluticasone propionate.
Get Free WhatsApp Updates!
Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
06 September 2012
Publication Number
10/2014
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application
Patent Number
Legal Status
Grant Date
2019-07-31
Renewal Date
Applicants
MYLAN LABORATORIES LTD
PLOT NO 564/A/22, ROAD NO 92, JUBILEE HILLS, HYDERABAD - 500 033
Inventors
1. PUNDE, DNYANDEO
PLOT NO 564/A/22, ROAD NO 92, JUBILEE HILLS, HYDERABAD - 500 033
2. BOHARA, CHANDERSINGH
PLOT NO 564/A/22, ROAD NO 92, JUBILEE HILLS, HYDERABAD - 500 033
3. POKHARKAR, KIRAN
PLOT NO 564/A/22, ROAD NO 92, JUBILEE HILLS, HYDERABAD - 500 033
4. GADAKAR, MAHESH KUMAR
PLOT NO 564/A/22, ROAD NO 92, JUBILEE HILLS, HYDERABAD - 500 033
5. GORE, VINAYAK
PLOT NO 564/A/22, ROAD NO 92, JUBILEE HILLS, HYDERABAD - 500 033
Specification
The present complete specification claims priority from IN 3689/CHE/2012, filed on Sep 9, 2012 and IN 5297/CHE/2012, filed on Dec 18, 2012.
FIELD OF THE INVENTION:
The present invention relates to an improved process for the preparation of Fluticasone propionate.
BACK GROUND OF THE INVENTION:
Fluticasone propionate and Fluticasone furoateare corticosteroids of the androstane family these are potent anti-inflammatory activity and are widely accepted as a useful therapy for the treatment of inflammatory and allergic conditions such as asthma and chronic obstructive pulmonary disease (COPD).
Fluticasone propionate is chemically known as 6a,9a-difluoro-17ot-(((fluoromethyl)sulfanyl)carbonyl)-11 (3-hydroxy-l6a-methyl-3-oxoandrosta-1,4-dien-17a-yl propionate and structurally represented as below.
US 4335121 patent discloses process for the preparation of Fluticasone propionate, wherein 6
Documents
Orders
| Section | Controller | Decision Date |
|---|---|---|
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 3689-CHE-2012 FORM-3 06-09-2012.pdf | 2012-09-06 |
| 1 | 3689-CHE-2012-RELEVANT DOCUMENTS [07-05-2021(online)].pdf | 2021-05-07 |
| 2 | 3689-CHE-2012 FORM-2 06-09-2012.pdf | 2012-09-06 |
| 2 | 3689-CHE-2012-RELEVANT DOCUMENTS [30-03-2020(online)].pdf | 2020-03-30 |
| 3 | 3689-CHE-2012-IntimationOfGrant31-07-2019.pdf | 2019-07-31 |
| 3 | 3689-CHE-2012 FORM-1 06-09-2012.pdf | 2012-09-06 |
| 4 | 3689-CHE-2012-PatentCertificate31-07-2019.pdf | 2019-07-31 |
| 4 | 3689-CHE-2012 CORRESPONDANCE OTHERS 06-09-2012.pdf | 2012-09-06 |
| 5 | Abstract_Granted 317251_31-07-2019.pdf | 2019-07-31 |
| 5 | 3689-CHE-2012 DESCRIPTION ( PROVISIONAL) 06-09-2012.pdf | 2012-09-06 |
| 6 | Claims_Granted 317251_31-07-2019.pdf | 2019-07-31 |
| 6 | 3689-CHE-2012 CORRESPONDENCE OTHERS 19-11-2012.pdf | 2012-11-19 |
| 7 | Description_Granted 317251_31-07-2019.pdf | 2019-07-31 |
| 7 | 3689-CHE-2012 FORM-1 19-11-2012.pdf | 2012-11-19 |
| 8 | Marked up Claims_Granted 317251_31-07-2019.pdf | 2019-07-31 |
| 8 | 3689-CHE-2012 DESCRIPTION (COMPLETE) 04-09-2013.pdf | 2013-09-04 |
| 9 | 3689-CHE-2012 FORM-5 04-09-2013.pdf | 2013-09-04 |
| 9 | 3689-CHE-2012-Written submissions and relevant documents (MANDATORY) [25-07-2019(online)].pdf | 2019-07-25 |
| 10 | 3689-CHE-2012 FORM-2 04-09-2013.pdf | 2013-09-04 |
| 10 | 3689-CHE-2012-Written submissions and relevant documents (MANDATORY) [05-07-2019(online)].pdf | 2019-07-05 |
| 11 | 3689-CHE-2012 CORRESPONDENCE OTHERS 04-09-2013.pdf | 2013-09-04 |
| 11 | 3689-CHE-2012-HearingNoticeLetter04-07-2019.pdf | 2019-07-04 |
| 12 | 3689-CHE-2012 CLAIMS 04-09-2013.pdf | 2013-09-04 |
| 12 | 3689-CHE-2012-Correspondence to notify the Controller (Mandatory) [03-07-2019(online)].pdf | 2019-07-03 |
| 13 | 3689-CHE-2012 ABSTRACT 04-09-2013.pdf | 2013-09-04 |
| 13 | 3689-CHE-2012-COMPLETE SPECIFICATION [26-02-2018(online)].pdf | 2018-02-26 |
| 14 | 3689-CHE-2012 FORM-18 30-9-2013.pdf | 2013-11-07 |
| 14 | 3689-CHE-2012-FER_SER_REPLY [26-02-2018(online)].pdf | 2018-02-26 |
| 15 | 3689-CHE-2012-FER.pdf | 2017-10-20 |
| 16 | 3689-CHE-2012 FORM-18 30-9-2013.pdf | 2013-11-07 |
| 16 | 3689-CHE-2012-FER_SER_REPLY [26-02-2018(online)].pdf | 2018-02-26 |
| 17 | 3689-CHE-2012-COMPLETE SPECIFICATION [26-02-2018(online)].pdf | 2018-02-26 |
| 17 | 3689-CHE-2012 ABSTRACT 04-09-2013.pdf | 2013-09-04 |
| 18 | 3689-CHE-2012-Correspondence to notify the Controller (Mandatory) [03-07-2019(online)].pdf | 2019-07-03 |
| 18 | 3689-CHE-2012 CLAIMS 04-09-2013.pdf | 2013-09-04 |
| 19 | 3689-CHE-2012 CORRESPONDENCE OTHERS 04-09-2013.pdf | 2013-09-04 |
| 19 | 3689-CHE-2012-HearingNoticeLetter04-07-2019.pdf | 2019-07-04 |
| 20 | 3689-CHE-2012 FORM-2 04-09-2013.pdf | 2013-09-04 |
| 20 | 3689-CHE-2012-Written submissions and relevant documents (MANDATORY) [05-07-2019(online)].pdf | 2019-07-05 |
| 21 | 3689-CHE-2012 FORM-5 04-09-2013.pdf | 2013-09-04 |
| 21 | 3689-CHE-2012-Written submissions and relevant documents (MANDATORY) [25-07-2019(online)].pdf | 2019-07-25 |
| 22 | 3689-CHE-2012 DESCRIPTION (COMPLETE) 04-09-2013.pdf | 2013-09-04 |
| 22 | Marked up Claims_Granted 317251_31-07-2019.pdf | 2019-07-31 |
| 23 | 3689-CHE-2012 FORM-1 19-11-2012.pdf | 2012-11-19 |
| 23 | Description_Granted 317251_31-07-2019.pdf | 2019-07-31 |
| 24 | 3689-CHE-2012 CORRESPONDENCE OTHERS 19-11-2012.pdf | 2012-11-19 |
| 24 | Claims_Granted 317251_31-07-2019.pdf | 2019-07-31 |
| 25 | Abstract_Granted 317251_31-07-2019.pdf | 2019-07-31 |
| 25 | 3689-CHE-2012 DESCRIPTION ( PROVISIONAL) 06-09-2012.pdf | 2012-09-06 |
| 26 | 3689-CHE-2012-PatentCertificate31-07-2019.pdf | 2019-07-31 |
| 26 | 3689-CHE-2012 CORRESPONDANCE OTHERS 06-09-2012.pdf | 2012-09-06 |
| 27 | 3689-CHE-2012-IntimationOfGrant31-07-2019.pdf | 2019-07-31 |
| 27 | 3689-CHE-2012 FORM-1 06-09-2012.pdf | 2012-09-06 |
| 28 | 3689-CHE-2012-RELEVANT DOCUMENTS [30-03-2020(online)].pdf | 2020-03-30 |
| 28 | 3689-CHE-2012 FORM-2 06-09-2012.pdf | 2012-09-06 |
| 29 | 3689-CHE-2012-RELEVANT DOCUMENTS [07-05-2021(online)].pdf | 2021-05-07 |
| 29 | 3689-CHE-2012 FORM-3 06-09-2012.pdf | 2012-09-06 |
Search Strategy
| 1 | search_18-09-2017.pdf |