Inhibitors Of 11 Beta Hydroxysteroid Dehydrogenase 1

Abstract: The present invention discloses novel compounds of Formula I: ( I ) possessing 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, cognitive disorders, and other conditions associated with 11β-HSD type 1 activity.

Patent Information

Application #

Filing Date

23 October 2008

Publication Number

03/2009

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

Parent Application

Patent Number

Legal Status

Grant Date

2013-02-20

Renewal Date

Applicants

ELI LILLY AND COMPANY

LILLY CORPORATE CENTER, INDIANAPOLIS, INDIANA 46285,

Inventors

1. LI, RENHUA

10493 Hollowood Court Fishers Indiana 46038 USA

2. WALLACE, OWEN, BRENDAN

13297 Mink Lane Westfield Indiana 46074 USA

3. XU, YANPING

6676 Pennan Court Noblesville Indiana 46062 USA

Specification

PLEASE SEE THE SPECIFICATION ATTACHED.

Documents

Application Documents

#	Name	Date
1	2277-mumnp-2008-wo international publication report(23-10-2008).pdf	2008-10-23
2	2277-mumnp-2008-form 5(23-10-2008).pdf	2008-10-23
3	2277-mumnp-2008-form 3(23-10-2008).pdf	2008-10-23
4	2277-mumnp-2008-form 2(title page)-(23-10-2008).pdf	2008-10-23
5	2277-mumnp-2008-form 2(23-10-2008).pdf	2008-10-23
6	2277-mumnp-2008-form 1(23-10-2008).pdf	2008-10-23
7	2277-mumnp-2008-description(complete)-(23-10-2008).pdf	2008-10-23
8	2277-mumnp-2008-claims(23-10-2008).pdf	2008-10-23
9	2277-mumnp-2008-abstract(23-10-2008).pdf	2008-10-23
10	2277-MUMNP-2008-CORRESPONDENCE(24-12-2008).pdf	2008-12-24
11	2277-MUMNP-2008-ASSIGNMENT(24-12-2008).pdf	2008-12-24
12	Form 27 [29-03-2016(online)].pdf	2016-03-29
13	Petition Under Rule 137 [11-04-2017(online)].pdf	2017-04-11
14	Form 27 [11-04-2017(online)].pdf	2017-04-11
15	ipindiaonline.gov.in_epatentfiling_online_frmPreview.asp.pdf	2018-08-09
16	Form-5.pdf	2018-08-09
17	Form-3.pdf	2018-08-09
18	Form-1.pdf	2018-08-09
19	abstract1.jpg	2018-08-09
20	2277-MUMNP-2008_EXAMREPORT.pdf	2018-08-09
21	2277-MUMNP-2008-US DOCUMENT(15-5-2012).pdf	2018-08-09
22	2277-MUMNP-2008-REPLY TO EXAMINATION REPORT(15-5-2012).pdf	2018-08-09
23	2277-MUMNP-2008-PETITION UNDER RULE-137(17-1-2013).pdf	2018-08-09
24	2277-MUMNP-2008-PETITION UNDER RULE 137(15-5-2012).pdf	2018-08-09
25	2277-MUMNP-2008-PCT CLAIMS(15-5-2012).pdf	2018-08-09
26	2277-mumnp-2008-marked copy(4-11-2008).pdf	2018-08-09
27	2277-MUMNP-2008-FORM2(GRANTED).pdf	2018-08-09
28	2277-MUMNP-2008-FORM 3(15-5-2012).pdf	2018-08-09
29	2277-MUMNP-2008-FORM 3(13-4-2009).pdf	2018-08-09
30	2277-MUMNP-2008-FORM 26(15-5-2012).pdf	2018-08-09
31	2277-MUMNP-2008-FORM 26(14-9-2011).pdf	2018-08-09
32	2277-MUMNP-2008-FORM 2(TITLE PAGE)-(GRANTED).pdf	2018-08-09
33	2277-mumnp-2008-form 18(4-11-2008).pdf	2018-08-09
34	2277-mumnp-2008-form 13(4-11-2008).pdf	2018-08-09
35	2277-MUMNP-2008-FORM 13(26-7-2012).pdf	2018-08-09
36	2277-MUMNP-2008-FORM 1(30-8-2012).pdf	2018-08-09
37	2277-MUMNP-2008-EP DOCUMENT(15-5-2012).pdf	2018-08-09
38	2277-MUMNP-2008-DESCRIPTION(GRANTED).pdf	2018-08-09
39	2277-MUMNP-2008-CORRESPONDENCE(IPO).pdf	2018-08-09
40	2277-MUMNP-2008-CORRESPONDENCE(30-8-2012).pdf	2018-08-09
41	2277-MUMNP-2008-CORRESPONDENCE(26-7-2012).pdf	2018-08-09
42	2277-MUMNP-2008-CORRESPONDENCE(17-1-2013).pdf	2018-08-09
43	2277-MUMNP-2008-CORRESPONDENCE(14-9-2011).pdf	2018-08-09
44	2277-MUMNP-2008-CORRESPONDENCE(13-4-2009).pdf	2018-08-09
45	2277-MUMNP-2008-CLAIMS(MARKED COPY)-(15-5-2012).pdf	2018-08-09
46	2277-MUMNP-2008-CLAIMS(GRANTED).pdf	2018-08-09
47	2277-mumnp-2008-claims(amended)-(4-11-2008).pdf	2018-08-09
48	2277-MUMNP-2008-CLAIMS(AMENDED)-(15-5-2012).pdf	2018-08-09