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“Inhibitors Of 11 Beta Hydroxysteroid Dehydrogenase 1”
Abstract: The present invention discloses novel compounds of Formula I: having 11 Beta-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11Beta-HSD type 1 activity. X-17377
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
19 September 2008
Publication Number
16/2009
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
postmaster@knspartners.com
Parent Application
Applicants
ELI LILLY AND COMPANY
Lilly Corporate Center Indianapolis Indiana 46285 USA
Inventors
1. LI, Renhua
10493 Hollowood Court Fishers Indiana 46038 USA
2. MABRY, Thomas, Edward
10624 Orchard Way Indianapolis Indiana 46280 USA
3. WALLACE, Owen, Brendan
13297 Mink Lane Westfield Indiana 46074 USA
4. WINNEROSKI, Leonard, Larry, Jr.
587 Thoroughbred Lane Greenwood Indiana 46142 USA
5. XU, Yanping
6676 Pennan Court Noblesville Indiana 46062 USA
Specification
PLEASE SEE THE SPECIFICATION ATTACHED.
Documents
Orders
| Section | Controller | Decision Date |
|---|---|---|
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 3787-KOLNP-2007-(17-10-2008)-FORM-13.pdf | 2008-10-17 |
| 1 | HEARING ADJOURNMENT [06-01-2017(online)].pdf | 2017-01-06 |
| 2 | Form-1.pdf | 2016-11-29 |
| 2 | Form-5.pdf | 2011-10-07 |
| 3 | Form1.pdf | 2016-11-29 |
| 3 | Form-3.pdf | 2011-10-07 |
| 4 | 3787-KOLNP-2008_EXAMREPORT.pdf | 2016-06-30 |
| 4 | 3787-KOLNP-2008-PCT REQUEST.pdf | 2011-10-07 |
| 5 | Abstract [17-06-2016(online)].pdf | 2016-06-17 |
| 5 | 3787-KOLNP-2008-PCT PRIORITY DOCUMENT NOTIFICATION.pdf | 2011-10-07 |
| 6 | Claims [17-06-2016(online)].pdf | 2016-06-17 |
| 6 | 3787-KOLNP-2008-INTERNATIONAL SEARCH REPORT.pdf | 2011-10-07 |
| 7 | Description(Complete) [17-06-2016(online)].pdf | 2016-06-17 |
| 7 | 3787-KOLNP-2008-INTERNATIONAL SEARCH REPORT 1.1.pdf | 2011-10-07 |
| 8 | Examination Report Reply Recieved [17-06-2016(online)].pdf | 2016-06-17 |
| 8 | 3787-KOLNP-2008-INTERNATIONAL PUBLICATION.pdf | 2011-10-07 |
| 9 | 3787-KOLNP-2008-INTERNATIONAL PRELIMINARY EXAMINATION REPORT.pdf | 2011-10-07 |
| 9 | OTHERS [17-06-2016(online)].pdf | 2016-06-17 |
| 10 | 3787-KOLNP-2008-GPA.pdf | 2011-10-07 |
| 10 | Petition Under Rule 137 [16-06-2016(online)].pdf | 2016-06-16 |
| 11 | 3787-KOLNP-2008-(30-11-2015)-CORRESPONDENCE.pdf | 2015-11-30 |
| 11 | 3787-KOLNP-2008-FORM 5.pdf | 2011-10-07 |
| 12 | 3787-KOLNP-2008-(30-11-2015)-FORM-3.pdf | 2015-11-30 |
| 12 | 3787-KOLNP-2008-FORM 3.pdf | 2011-10-07 |
| 13 | 3787-KOLNP-2008-(30-11-2015)-OTHERS.pdf | 2015-11-30 |
| 13 | 3787-KOLNP-2008-FORM 2.pdf | 2011-10-07 |
| 14 | 3787-KOLNP-2008-(07-08-2015)-CORRESPONDENCE.pdf | 2015-08-07 |
| 14 | 3787-kolnp-2008-form 18.pdf | 2011-10-07 |
| 15 | 3787-KOLNP-2008-(07-08-2015)-PA.pdf | 2015-08-07 |
| 15 | 3787-KOLNP-2008-FORM 13.pdf | 2011-10-07 |
| 16 | 3787-KOLNP-2008-(15-07-2015)-CORRESPONDENCE.pdf | 2015-07-15 |
| 16 | 3787-KOLNP-2008-FORM 1.pdf | 2011-10-07 |
| 17 | 3787-KOLNP-2008-DESCRIPTION COMPLETE.pdf | 2011-10-07 |
| 17 | 3787-KOLNP-2008-(15-07-2015)-OTHERS.pdf | 2015-07-15 |
| 18 | 3787-KOLNP-2008-(06-06-2014)-CORRESPONDENCE.pdf | 2014-06-06 |
| 18 | 3787-KOLNP-2008-CORRESPONDENCE.pdf | 2011-10-07 |
| 19 | 3787-KOLNP-2008-(25-10-2012)-CORRESPONDENCE.pdf | 2012-10-25 |
| 19 | 3787-KOLNP-2008-CORRESPONDENCE-1.2.pdf | 2011-10-07 |
| 20 | 3787-KOLNP-2008-(25-10-2012)-FORM-1.pdf | 2012-10-25 |
| 20 | 3787-KOLNP-2008-CORRESPONDENCE 1.1.pdf | 2011-10-07 |
| 21 | 3787-KOLNP-2008-(25-10-2012)-OTHERS.pdf | 2012-10-25 |
| 21 | 3787-KOLNP-2008-CLAIMS.pdf | 2011-10-07 |
| 22 | 3787-KOLNP-2008-(12-09-2012)-CORRESPONDENCE.pdf | 2012-09-12 |
| 22 | 3787-KOLNP-2008-ABSTRACT.pdf | 2011-10-07 |
| 23 | 3787-KOLNP-2008-(12-09-2012)-FORM-3.pdf | 2012-09-12 |
| 23 | 3787-KOLNP-2008-(12-09-2012)-PA.pdf | 2012-09-12 |
| 24 | 3787-KOLNP-2008-(12-09-2012)-PA.pdf | 2012-09-12 |
| 24 | 3787-KOLNP-2008-(12-09-2012)-FORM-3.pdf | 2012-09-12 |
| 25 | 3787-KOLNP-2008-(12-09-2012)-CORRESPONDENCE.pdf | 2012-09-12 |
| 25 | 3787-KOLNP-2008-ABSTRACT.pdf | 2011-10-07 |
| 26 | 3787-KOLNP-2008-(25-10-2012)-OTHERS.pdf | 2012-10-25 |
| 26 | 3787-KOLNP-2008-CLAIMS.pdf | 2011-10-07 |
| 27 | 3787-KOLNP-2008-(25-10-2012)-FORM-1.pdf | 2012-10-25 |
| 27 | 3787-KOLNP-2008-CORRESPONDENCE 1.1.pdf | 2011-10-07 |
| 28 | 3787-KOLNP-2008-(25-10-2012)-CORRESPONDENCE.pdf | 2012-10-25 |
| 28 | 3787-KOLNP-2008-CORRESPONDENCE-1.2.pdf | 2011-10-07 |
| 29 | 3787-KOLNP-2008-(06-06-2014)-CORRESPONDENCE.pdf | 2014-06-06 |
| 29 | 3787-KOLNP-2008-CORRESPONDENCE.pdf | 2011-10-07 |
| 30 | 3787-KOLNP-2008-(15-07-2015)-OTHERS.pdf | 2015-07-15 |
| 30 | 3787-KOLNP-2008-DESCRIPTION COMPLETE.pdf | 2011-10-07 |
| 31 | 3787-KOLNP-2008-(15-07-2015)-CORRESPONDENCE.pdf | 2015-07-15 |
| 31 | 3787-KOLNP-2008-FORM 1.pdf | 2011-10-07 |
| 32 | 3787-KOLNP-2008-(07-08-2015)-PA.pdf | 2015-08-07 |
| 32 | 3787-KOLNP-2008-FORM 13.pdf | 2011-10-07 |
| 33 | 3787-KOLNP-2008-(07-08-2015)-CORRESPONDENCE.pdf | 2015-08-07 |
| 33 | 3787-kolnp-2008-form 18.pdf | 2011-10-07 |
| 34 | 3787-KOLNP-2008-(30-11-2015)-OTHERS.pdf | 2015-11-30 |
| 34 | 3787-KOLNP-2008-FORM 2.pdf | 2011-10-07 |
| 35 | 3787-KOLNP-2008-(30-11-2015)-FORM-3.pdf | 2015-11-30 |
| 35 | 3787-KOLNP-2008-FORM 3.pdf | 2011-10-07 |
| 36 | 3787-KOLNP-2008-FORM 5.pdf | 2011-10-07 |
| 36 | 3787-KOLNP-2008-(30-11-2015)-CORRESPONDENCE.pdf | 2015-11-30 |
| 37 | 3787-KOLNP-2008-GPA.pdf | 2011-10-07 |
| 37 | Petition Under Rule 137 [16-06-2016(online)].pdf | 2016-06-16 |
| 38 | 3787-KOLNP-2008-INTERNATIONAL PRELIMINARY EXAMINATION REPORT.pdf | 2011-10-07 |
| 38 | OTHERS [17-06-2016(online)].pdf | 2016-06-17 |
| 39 | 3787-KOLNP-2008-INTERNATIONAL PUBLICATION.pdf | 2011-10-07 |
| 39 | Examination Report Reply Recieved [17-06-2016(online)].pdf | 2016-06-17 |
| 40 | 3787-KOLNP-2008-INTERNATIONAL SEARCH REPORT 1.1.pdf | 2011-10-07 |
| 40 | Description(Complete) [17-06-2016(online)].pdf | 2016-06-17 |
| 41 | 3787-KOLNP-2008-INTERNATIONAL SEARCH REPORT.pdf | 2011-10-07 |
| 41 | Claims [17-06-2016(online)].pdf | 2016-06-17 |
| 42 | Abstract [17-06-2016(online)].pdf | 2016-06-17 |
| 42 | 3787-KOLNP-2008-PCT PRIORITY DOCUMENT NOTIFICATION.pdf | 2011-10-07 |
| 43 | 3787-KOLNP-2008_EXAMREPORT.pdf | 2016-06-30 |
| 43 | 3787-KOLNP-2008-PCT REQUEST.pdf | 2011-10-07 |
| 44 | Form1.pdf | 2016-11-29 |
| 44 | Form-3.pdf | 2011-10-07 |
| 45 | Form-5.pdf | 2011-10-07 |
| 45 | Form-1.pdf | 2016-11-29 |
| 46 | HEARING ADJOURNMENT [06-01-2017(online)].pdf | 2017-01-06 |
| 46 | 3787-KOLNP-2007-(17-10-2008)-FORM-13.pdf | 2008-10-17 |