DESC:
FIELD OF THE INVENTION
[0001] The present disclosure relates to technical field of insecticidal composition. More particularly, the present disclosure relates to insecticide composition in the form of bait comprising a combination of indoxacarb and propoxur, and to methods of using the same to control harmful and unwanted terrestrial insects.

BACKGROUND OF THE INVENTION
[0002] Background description includes information that may be useful in understanding the present invention. It is not an admission that any of the information provided herein is prior art or relevant to the presently claimed invention, or that any publication specifically or implicitly referenced is prior art.
[0003] Most of the insects pose a threat to hygiene and are a nuisance to humans and animals. Various insecticides can be employed in a wide variety of preparation forms in control of these insects. For example, mention may be made of spray compositions, dusts, spray cans and different types of baits. Since insects are often found within fairly close living range of humans and of domestic animals, they must be controlled. Bait preparations are increasingly gaining in importance because of their comparatively low endangerment of humans and domestic animals and because of their very generally high environmental friendliness. Furthermore, baits containing an insecticide make possible introduction into the resting places of insects, which leads to complete eradication of the insect colony, which can scarcely be achieved using other processes.
[0004] Cockroach as an amazing creature that would be fascinating to everyone if there were not such a pest. Their ability to adapt is what makes them such a pest that they will probably never be put on the endangered species list. Over the years we have seen that many pest control management programs failed because resistance has been developed in cockroaches upon using the same insecticide over the years. If a population of cockroaches becomes resistant to an insecticide, then it is always a possibility that that population may develop resistant to many insecticides in that particular drug class. The basic way of approach to challenge the developed resistance is to develop a combination of more than one insecticide with different mode of action.
[0005] In recent years, there have been used a great number of chemicals having insecticidal activities in order to control various insects. The number of insecticidal active substances, which are suitable for use in an insect bait is also very large. Various methods and compositions for application of insecticide containing bait are also described in the prior art. The efficiency of such compositions is improved by inclusion of various additives. Pastes or gels provide especially preferred emulsion type composition for delivery of insecticidally active ingredients together with food sources for the target insect.
[0006] In view of such situation, it is desirable to develop an insecticidal combination having broad insecticidal activity spectrum against a wide variety of insects, which are closely related to human and animal living areas, and a long residual effect to prevent subsequent growth of insects without any lethal toxicity to human and animals.
[0007] In contrast, it is more sensible to be able to employ insecticidal combination which has proven sufficiently effective and able to control multiple type of insects for as long as possible, especially when it has shown itself to be environmentally compatible to a particularly high degree and to possess only minimal side-effects.
[0008] Methyl(S)-N-[7-chloro-2,3,4a,5-tetrahydro-4a-(methoxycarbonyl)indeno[1,2e][1,3,4] oxadiazin-2-ylcarbonyl]-4'-(trifluoromethoxy) carbanilate, generally called as ‘indoxacarb’ is an insecticide having sodium channel blocker activity in insect nerve cells. Its route of action is by contact and ingestion. Affected insects cease feeding, with poor co-ordination, paralysis and ultimately death. It can be used to control a broad spectrum of pests, particularly worms, bugs, home pests specifically cockroaches, fire ants, ants, weevils and mole crickets in sod, turf and lawns. Its insecticidal activity is described in book entitled “The Pesticide Manual” published by the British Crop Protection Council, 17th edition, 2015, page 639.
[0009] 2-isopropoxyphenyl methylcarbamate, generally called as ‘propoxur’ is a non-systemic cholinesterase inhibitor with contact and stomach action. Propoxur has a fast knockdown and long residual effect against turf, forestry, and household pests like cockroaches, flies, fleas, mosquitoes, bugs, ants, millipedes and other insects pests found in food storage areas, houses, animal houses etc. and also against migratory insects like locusts and grasshoppers. Its insecticidal activity is described in book entitled “The Pesticide Manual” published by the British Crop Protection Council, 17th edition, 2015, page 933.
[00010] IN2011CH01533 and IN2012CH02257 describes an insecticidal gel compound and a method of its use, especially for the control of crawling and flying insects having fipronil, imidacloprid, thiamethoxam, or indoxacarb as active ingredient.
[00011] WO2012010509 equivalent to IN2013DN00564 describes a gel bait for controlling harmful insects, which is composed of insecticide encapsulated in a water-insoluble polymer, together with food, attractant, eating stimulant, and dye. The insecticides disclosed are clothianidin, imidacloprid, fipronil, spinosad, indoxacarb, and abamectin.
[00012] WO2012107266 describes a poison bait-type insecticidal compound and a method for preparing it, which contains inactivated dry yeast for attracting cockroaches and one or more of fipronil, hydramethylnon, chlorpyrifos, propoxol, indoxacarb, boric acid and fenitrothion insecticide.
[00013] WO2017079684 describes insecticidal bait composition for cockroaches which includes a lethal agent and dry malt extract or one or more isolated additives. The lethal agent comprises one or more of a chemical agent, a pathogen, a physical abrasive, and a trap.
[00014] However, insecticide bait composition containing a combination of indoxacarb and propoxur has not hitherto been reported in the art. In spite of the efforts mentioned in the field of insecticides, there still remains a need in the art for new and improved insecticide composition in the form of bait formulation that exhibits improved insecticidal properties, possess advantageous activity profile and offers improved stability.
[00015] The present disclosure satisfies the existing needs, as well as others, and generally overcomes the deficiencies found in the prior art.
[00016] All publications herein are incorporated by reference to the same extent as if each individual publication or patent application were specifically and individually indicated to be incorporated by reference. Where a definition or use of a term in an incorporated reference is inconsistent or contrary to the definition of that term provided herein, the definition of that term provided herein applies and the definition of that term in the reference does not apply.
[00017] Groupings of alternative elements or embodiments of the invention disclosed herein are not to be construed as limitations. Each group member can be referred to and claimed individually or in any combination with other members of the group or other elements found herein. One or more members of a group can be included in, or deleted from, a group for reasons of convenience and/or patentability.

OBJECTS OF THE INVENTION
[00018] It is an object of the present disclosure to provide an insecticide bait composition that is highly effective and exhibits broad spectrum insecticidal activities.
[00019] It is another object of the present disclosure to provide an insecticide bait composition that exhibits both physical and chemical stability and remains useful for a long period of time.
[00020] It is another object of the present disclosure to provide an insecticide bait composition which is easy to prepare (formulate) and use (apply), and as well as safe to the environment.
[00021] It is another object of the present disclosure to provide an insecticide bait composition which is effective for use in controlling one or more immature and mature stages of terrestrial insects or other arthropod pests, more particularly, in controlling cockroaches.
[00022] It is another object of the present disclosure to provide a feeding bait stimulant composition which can stimulate cockroach feeding for long periods of time and into which an active insecticide can be formulated to produce a lethal dose of toxicant in the cockroach.
[00023] It is another object of the present disclosure to provide an insecticide bait composition which is highly effective on broad range of terrestrial insect species found in houses, hotels, restaurants, food storage areas, animal houses, dining rooms, dormitories, offices, canteens, production workshops and other work places.
[00024] It is another object of the present disclosure to provide an insecticide bait composition which can attract and eradicate insects, particularly cockroaches.
[00025] It is another object of the present disclosure to provide an insecticide composition, in the form of bait formulation, which exhibits stable insecticidal effect for a long period of time.
[00026] It is another object of the present disclosure to provide insecticide bait, in a stable gel form, for applying to places where cockroaches go into hiding.
[00027] It is yet another object of the present disclosure to provide an insecticide composition which is highly effective against various insects including ants, cockroaches, weevils, crickets, flies, bugs, millipedes and other terrestrial insect pests found in household and food storage areas.

SUMMARY
[00028] Aspects of the present disclosure relate to an insecticidal bait composition useful for control of undesired and/or harmful terrestrial insects, method of preparation of the insecticidal bait composition, and methods of using the insecticidal bait composition to control insects.
[00029] According to one aspect of the present disclosure there is provided an insecticidal bait composition for control of undesired and harmful terrestrial insects, particularly cockroaches, which comprises an effective amount of indoxacarb in combination with an effective amount of propoxur. The disclosed insecticidal bait composition can remain in a stable form to be readily available for ingestion by insects and can exhibit stable insecticidal effect for a long period of time. Further, the disclosed insecticidal bait composition can exhibit a synergistic effect when compared to the individual use of the mentioned insecticides.
[00030] According to embodiments of the present disclosure, the insecticidal bait composition of the present disclosure can be formulated in solid or semi-solid form using one or more formulation additives. In one preferred embodiment, the insecticidal bait composition of the present disclosure can be prepared in the form of gel for controlling/exterminating cockroaches.
[00031] Another aspect of the present disclosure is directed to a method of controlling harmful terrestrial insects, the method comprising exposing said insects to an effective amount of a bait composition comprising a combination of indoxacarb and propoxur.
[00032] Various objects, features, aspects and advantages of the inventive subject matter will become more apparent from the following detailed description of preferred embodiments.

DETAILED DESCRIPTION OF THE INVENTION
[00033] The following is a detailed description of embodiments of the present disclosure. The embodiments are in such detail as to clearly communicate the disclosure. However, the amount of detail offered is not intended to limit the anticipated variations of embodiments; on the contrary, the intention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the present disclosure as defined by the appended claims.
[00034] Unless the context requires otherwise, throughout the specification which follow, the word “comprise” and variations thereof, such as, “comprises” and “comprising” are to be construed in an open, inclusive sense that is as “including, but not limited to.”
[00035] Reference throughout this specification to “one embodiment” or “an embodiment” means that a particular feature, structure or characteristic described in connection with the embodiment is included in at least one embodiment. Thus, the appearances of the phrases “in one embodiment” or “in an embodiment” in various places throughout this specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures, or characteristics may be combined in any suitable manner in one or more embodiments.
[00036] As used in the description herein and throughout the claims that follow, the meaning of “a,” “an,” and “the” includes plural reference unless the context clearly dictates otherwise. Also, as used in the description herein, the meaning of “in” includes “in” and “on” unless the context clearly dictates otherwise.
[00037] In some embodiments, the numbers expressing quantities of ingredients, properties such as concentration, process conditions, and so forth, used to describe and claim certain embodiments of the invention are to be understood as being modified in some instances by the term “about.” Accordingly, in some embodiments, the numerical parameters set forth in the written description are approximations that can vary depending upon the desired properties sought to be obtained by a particular embodiment. In some embodiments, the numerical parameters should be construed in light of the number of reported significant digits and by applying ordinary rounding techniques. Notwithstanding that the numerical ranges and parameters setting forth the broad scope of some embodiments of the invention are approximations, the numerical values set forth in the specific examples are reported as precisely as practicable.
[00038] The recitation of ranges of values herein is merely intended to serve as a shorthand method of referring individually to each separate value falling within the range. Unless otherwise indicated herein, each individual value is incorporated into the specification as if it were individually recited herein.
[00039] All methods described herein can be performed in suitable order unless otherwise indicated herein or otherwise clearly contradicted by context. The use of any and all examples, or exemplary language (e.g. “such as”) provided with respect to certain embodiments herein is intended merely to better illuminate the invention and does not pose a limitation on the scope of the invention otherwise claimed. No language in the specification should be construed as indicating any non-claimed element essential to the practice of the invention.
[00040] The headings and abstract of the invention provided herein are for convenience only and do not interpret the scope or meaning of the embodiments.
[00041] Various terms are used herein. To the extent a term used in a claim is not defined below, it should be given the broadest definition persons in the pertinent art have given that term as reflected in printed publications and issued patents at the time of filing.
[00042] As used herein, the terms "active ingredient(s) or insecticide active ingredient(s) refer to the chemicals in pesticide products that kill, control, or repel pests.
[00043] The terms "insecticide" and "insecticidal" are used herein to denote the control of undesired terrestrial insects. The term “control” or “controlling” includes all deviations, such as total killing, growth retardation and regulation of all stages of insect life cycle.
[00044] As used herein, the term "gelling agents" refers to a variety of hydrophilic substances used to form a gel by increasing the viscosity and yield point of liquid mixtures.
[00045] As used herein, the terms "attractants" are inert ingredients that act in one or several of the following ways: a) entice the insect to approach the bait; b) entice the insect to touch the bait; c) entice the insect to consume the bait; d) entice the insect to return to the bait.
[00046] Inert ingredients that are able to achieve these goals belong to the group of food attractants.
[00047] In one aspect, the present disclosure is directed to an insecticidal bait composition for control of undesired and harmful terrestrial insects, particularly cockroaches, which comprises an effective amount of indoxacarb in combination with an effective amount of propoxur. The disclosed insecticidal bait composition can remain in a stable form to be readily available for ingestion by insects for a long period of time. The active ingredients indoxacarb and propoxur when used in combination as a binary mixture in quantities that, if used alone would be ineffective, show unexpected improved insecticidal effects. Further, the disclosed insecticidal bait composition can exhibit broad spectrum insecticidal activities and provide stable insecticidal effect for a prolonged period of time.
[00048] Insects, especially cockroaches, are omnivorous insects. These insects typically infest locations that contain sufficient food, moisture and shelter for survival. Cockroaches forage for food randomly and will examine a food prior to ingesting it. If the food does not contain ingredients that stimulate feeding of the insect, the cockroach may continue to forage for appropriate food sources. An avoidance or lack of feeding on a bait containing poisonous material may reduce the effectiveness of the insecticide against cockroaches under field conditions. Therefore, the embodiment of this invention is to formulate an insect bait, in particular a cockroach bait, that will be preferentially consumed in high quantities by cockroaches under both laboratory and field conditions.
[00049] In an embodiment, the insecticidal bait composition of the present disclosure can be employed for complete control of terrestrial harmful insects. Exemplary insects that can be controlled/exterminated by the insecticidal bait composition and method of the present disclosure include, but not limited to, German cockroach (Blatella germanica), oriental cockroach (Blatta orientalis), American cockroach (Periplaneta americana), brown banded cockroach (Supella longipalpa), Australian cockroach (Periplaneta australasiae), smoky brown cockroach (Periplaneta fuliginosa), fire ants (Solenopsis spp.), argentine ants (Linepithema humile), pharaoh ants (Monomorium pharaonis), little black ants (Monomorium spp.), carpenter ants (Camponotus spp.), ghost ants (Tapinoma spp.), big-headed ants (Pheidole spp.), white-footed ants (Technomyrmex albipes), houseflies (Musca domestica), lesser house flies, blowflies, cluster flies, midges, crane flies, fruit flies, weevils, crickets, flies, bugs, millipedes and other pest species that enter homes, food storage, animal houses and other workplaces.
[00050] According to embodiments of the present disclosure, the disclosed insecticidal bait composition can be formulated in any suitable form such as, but not limited to, emulsion concentrate, gel, cake, granules, suspension concentrate, wettable powders, water dispersible granules, microemulsion, suspoemulsion, soluble concentrate and dustable powder. Such formulations can be packaged in a single package and utilized as ready-to-use baits. The formulations may be prepared by any of the methods well known in the relevant art. Examples of preferred additives that can be used to formulate the insecticidal bait composition of the present disclosure can include, but not limited to, surfactants, aqueous and non-aqueous solvents, rheology modifiers or gelling agents, anti-freezing agents, biocides, pigments or colorants, food materials, attractants or sweetening agents, edible carriers, flavoring agents, bittering agents or repellants, inert materials and other auxiliaries customary in insecticidal bait preparations.
[00051] In an embodiment, indoxacarb can present in the insecticidal bait composition of the present disclosure in an amount ranging from 0.01% to 10% by weight, preferably from 0.1% to 1% by weight, more preferably 0.2% to 0.3% by weight, based on a total weight of the composition.
[00052] In an embodiment, propoxur can present in the insecticidal bait composition of the present disclosure in an amount ranging from 0.1% to 25% by weight, preferably from 1% to 5% by weight, more preferably from 1.5% to 2% by weight based on a total weight of the composition.
[00053] In one preferred embodiment, the disclosed insecticidal bait composition can be prepared in the form of gel using one or more suitable additives.
[00054] In an embodiment, the gel bait composition can include indoxacarb and propoxur as active ingredients, at least one rheology modifier (or gelling agent), at least one surfactant, at least one biocide agent, at least one attractant and at least one anti-freezing agent.
[00055] In another embodiment, the gel bait composition can further include one or more agents selected from the group consisting of a bittering agent, a solvent, a colouring agent and a filler.
[00056] In one embodiment, the gel bait insecticidal composition can optionally contain one or more surfactants, such as for example wetting agents, tackifiers, dispersing agents or emulsifiers, which are usually employed for this purpose in agrochemical compositions.
[00057] In one embodiment, the gel bait insecticidal composition can optionally contain one or more solvents which are usually employed for this purpose in agrochemical compositions.
[00058] In one embodiment, the gel bait insecticidal composition can contain one or more rheology modifiers or gelling agents which are usually employed for this purpose in agrochemical compositions. Suitable gelling agents are any among a multiplicity of hydrophilic substances which are used for forming a gel by increasing the viscosity and the yield point of fluid mixtures.
[00059] In one embodiment, the gel bait insecticidal composition can optionally contain one or more anti-freezing agents which are usually employed for this purpose in agrochemical compositions.
[00060] In one embodiment, the gel bait insecticidal composition can optionally contain one or more biocides which are usually employed for this purpose in agrochemical compositions.
[00061] In one embodiment, the gel bait insecticidal composition can optionally contain one or more coloring agents which are usually employed for this purpose in agrochemical compositions.
[00062] In one embodiment, the gel bait insecticidal composition can optionally contain one or more sweetening agent or attractants which are usually employed for this purpose in agrochemical compositions.
[00063] In one embodiment, the gel bait insecticidal composition can optionally contain one or more bittering agents or repellants which are usually employed for this purpose in agrochemical compositions.
[00064] In one embodiment, the gel bait insecticidal composition can optionally contain one or more fillers or inert materials, which may be mixed in the composition in any ratio and may be selected from water, for example tap water or distilled water.
[00065] In another embodiment, the gel bait composition can further include one or more suitable auxiliary materials which are usually employed for this purpose in agrochemical compositions and customary for preparing different type of bait compositions, known by a person skilled in the art.
[00066] In one embodiment, the disclosed insecticidal bait composition includes indoxacarb, propoxur and one or more auxiliary materials, where one auxiliary material may play a role of two or three different auxiliary types.
[00067] In one exemplary embodiment, the insecticidal gel bait composition can include indoxacarb and propoxur as active ingredients, ethoxylated tristyrylphenol as surfactant, diethylene glycol monobutyl ether as solvent, xanthan gum as rheology modifier, glycerol as anti-freezing agent, 1,2-benzisothiazolin-3-one as biocide, C.I. pigment Red 170 as coloring agent, fructose as attractant, sucrose octaacetate as bittering agent, and water as filler or inert material.
[00068] In one particularly preferred embodiment, the gel formulation of the disclosed insecticidal bait composition can include:
Ingredients Preferred weight %
Propoxur (purity min. 98% w/w)
(Insecticide) 0.1 to 25
Indoxacarb (purity min. 94% w/w as ‘S’ isomer) (Insecticide) 0.01 to 10
Ethoxylated tristyrylphenol
(Surfactant) 0.5 to 30
Diethylene glycol monobutyl ether
(Solvent) 0.01 to 80
Xanthan gum
(Rheology agent) 0.1 to 50
Glycerol
(Antifreezing agent) 0.10 to 50
1,2-Benzisothiazolin-3-one
(Biocide) 0.01 to 10
C.I. pigment Red 170
(Colouring agent) 0.01 to 10
Fructose
(Attractant) 1.00 to 98
Sucrose octaacetate
(Bittering agent) 0.001 to 0.5
Water
(Inert) 1.00 to 50

[00069] For the purposes of the present invention, gels are colloids in which the dispersed phase has combined with the continuous phase to give a jelly-like product with the following properties: dynamic viscosity of between 3,000 and 100,000 mPas, preferably 3,000 to 10,000 mPas (25°C, rotary viscometer, shear rate 10/s).
[00070] The insecticidal bait composition of the present disclosure is generally durable under environmental conditions in which terrestrial insects thrive, including moist environments. Thus, the insecticidal bait composition desirably retains its physical and chemical integrity after being exposed to the weather (precipitation, UV light, heat, air oxidation and hydrolysis and leaching) for one month or more.
[00071] The required application rate of the composition comprising the combination of indoxacarb and propoxur may depend on the density of undesired insects, type of location, development stage of insects and climatic conditions of location where the composition is to be used and also on the application method.
[00072] In another aspect, the present disclosure provides an insecticidal composition in the form of gel or emulsion for attracting and exterminating cockroaches, wherein the composition comprising a combination of indoxacarb and propoxur together with one or more additives. Gel or emulsion formulation is preferred because gels and emulsions are administered to cockroaches more conveniently than liquids. Moreover, gels and emulsions are conveniently packaged in tubes and injected into cracks and crevices where cockroaches typically nest. Similarly, insect bait formulated as an emulsion or gel is preferred for attracting and exterminating flies.
[00073] Another aspect of the present disclosure is directed to a method for controlling insects, particularly cockroaches comprising applying in the vicinity of their habitat or infested area an insecticidal bait composition consisting essentially of an insecticidally effective amount of indoxacarb and propoxur and/or the bait/feeding composition containing feeding bait stimulant composition according to the present disclosure. Additional edible carriers such as fructose, sugars, and the like may be added and the mixture blended until homogeneous.
[00074] In another aspect, the present disclosure provides a process for preparing an insecticidal gel bait composition containing indoxacarb, propoxur and one or more additives, wherein sequence of mixing or adding the active ingredients and the one or more additives can be interchanged according to the suitability of manufacturing process.
[00075] While the foregoing description discloses various embodiments of the disclosure, other and further embodiments of the invention may be devised without departing from the basic scope of the disclosure. The invention is not limited to the described embodiments, versions or examples, which are included to enable a person having ordinary skill in the art to make and use the invention when combined with information and knowledge available to the person having ordinary skill in the art.

EXAMPLES
[00076] The present disclosure is further explained in the form of following examples. However, it is to be understood that the foregoing examples are merely illustrative and are not to be taken as limitations upon the scope of the invention. Various changes and modifications to the disclosed embodiments will be apparent to those skilled in the art. Such changes and modifications may be made without departing from the scope of the invention.

Example 1: Method of preparing gel bait composition:
[00077] In a vessel, charge weighed quantity of glycerol (17 gm), sucrose octaacetate (0.01 gm) and 1,2-benzisothiazolin-3-one (0.5 gm) and stir to obtain homogeneous mixture. Then add xanthan gum (5 gm) slowly to this mixture with constant stirring to get slurry. Transfer this slurry slowly to another vessel, which is already having water (27.37 gm) in it at high speed stirring. Continue stirring till homogeneous gel is prepared. Allow to keep at room temperature for 12 to 15 hr. Separate this gel into two separate vessels. In one vessel, add weighed quantity of diethylene glycol monobutylether (6 gm), ethoxylated tristyrylphenol (7 gm), propoxur (1.8 gm) and indoxacarb (0.3 gm) and stir till completely miscible (mixture-1). In another vessel, charge weighed quantity of fructose (35 gm) and pigment (0.02 gm) at high speed stirring at room temperature and stir till homogeneous mixture obtained (mixture-2). Now add mixture-1, as obtained earlier, to this mixture-2 under high speed stirring at room temperature. Stir well till homogeneous gel bait is prepared. The final viscosity of the prepared gel was determined at 25°C at 100 rpm.
[00078] The numerical values of various parameters given in the specification are at approximations and slightly higher or slightly lower values of these parameters fall within the ambit and the scope of the invention.
[00079] While considerable emphasis has been placed herein on the specific steps of the preferred process, it will be highly appreciated that many steps can be made and that many changes can be made in the preferred steps without departing from the principles of the invention. These and other changes in the preferred steps of the invention will be apparent to those skilled in the art from the disclosures herein, whereby it is to be distinctly understood that the foregoing descriptive matter is to be interpreted merely as illustrative of the invention and not as a limitation.
[00080] Both the method and the gel bait according to the present disclosure have various advantages:
i) Ready to use and very easy to apply.
ii) Advantageous activity profile and high chemical and physical stability even after storage and transport.
iii) Rapid onset of activity and which also show optimum activity at the point in time of application.
iv) Also having good activity against larvae and nymphs stages of insects, which controls terrestrial insects for long periods of time.
v) Neither decomposed nor volatilized after application.
vi) Reduced application rate in comparison with the individual application of active ingredient.
vii) The big advantage with gel bait is that it is more effective than sprays or other over-the-counter treatments and does not produce fumes.
viii) Every cockroach that feeds on it can kill other cockroaches. This is because cockroaches eat the gel and take it back to their nest, where they share it with other cockroaches.
ix) Gel bait is in gel form and thick enough to stay in one place without evaporating or losing effectiveness.
x) Gel bait is easily placeable in insect harborage for maximum effectiveness. The gel can be squeezed from a syringe or any other means, so we can apply it precisely where its need is most.
xi) Entire area need not be covered, because pest goes to bait.
xii) Gel bait compositions are odorless, produce no vapors, have low human toxicity.
xiii) Gel bait compositions have low human or pet exposure.
xiv) Applicator exposure is minimal and environmental impact is also reduced due to the targeted concept.
,CLAIMS:

1. An insecticidal bait composition comprising indoxacarb in combination with propoxur.

2. The insecticidal bait composition as claimed in claim 1, wherein said indoxacarb is present in an amount ranging from 0.01 to 10% by weight based on a total weight of said bait composition.

3. The insecticidal bait composition as claimed in claim 1, wherein said propoxur is present in an amount ranging from 0.1 to 25% by weight based on a total weight of said bait composition.

4. The insecticidal bait composition as claimed in claim 1, wherein said bait composition is a terrestrial insect bait composition.

5. The insecticidal bait composition as claimed in claim 1, wherein said bait composition is a cockroach bait composition.

6. The insecticidal bait composition as claimed in claim 1, wherein said bait composition is in a solid form or a semi-solid form.

7. The insecticidal bait composition as claimed in claim 1, wherein said bait composition is in a form of a gel.

8. The insecticidal bait composition as claimed in claim 1, wherein said bait composition further comprises at least one rheology modifier, at least one surfactant, at least one biocide, at least one attractant and at least one anti-freezing agent.

9. The insecticidal bait composition as claimed in claim 8, wherein said bait composition further comprises at least one of a bittering agent, a solvent, a colouring agent and a filler.
10. An insecticidal bait composition comprising, on a weight basis: 0.01 to 10% indoxacarb, 0.1 to 25% propoxur, 0.1 to 50% xanthan gum, 0.5 to 30% ethoxylated tristyrylphenol, 0.01 to 10% 1,2-benzisothiazolin-3-one, 1 to 98% fructose, 0.10 to 50% glycerol, 0.001 to 0.5% sucrose octaacetate, 0.01 to 80% diethylene glycol monobutyl ether, 0.01 to 10% C.I. pigment Red 170 and 1 to 50% water.