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Lewis Acid Solutions In An Oxygen Donor Containing Solvent Or Solvent Mixture

Abstract: 121212The invention relates to solutions of Lewis acids selected from the halogen containing Lewis acids of the elements of groups 8 12 and 13 from the periodic table of elements or mixtures of said Lewis acids in aprotic asymmetrically substituted ethers of formula (I) or in solvent mixtures that contain asymmetrically substituted ethers and hydrocarbons and to the production of the solutions according to the invention. Said solutions can be used in the inorganic organic and organometallic synthesis where R ? R and R R independently of one another are selected from H or from a functionalized or a non functionalized branched or unbranched alkyl  alkyloxy cycloalkyl cycloalkyloxy group having 1 to 20 C atoms or an aryl or an aryloxy group having 1 12 C atoms wherein in the event that R = H R ? H.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
08 October 2012
Publication Number
17/2016
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

1. CHEMETALL GMBH
Trakehner Straße 3 60487 Frankfurt am Main

Inventors

1. WIETELMANN Ulrich
Rodheimer Straße 19 61381 Friedrichsdorf
2. MURSO Alexander
Poststrasse 4 38704 Liebenburg
3. LANG Sebastian
Bachstr. 2a 64347 Griesheim

Specification

Lewis acid solutions in an oxygen donor-containing solvent ^ or solvent mixture The invention relates to Lewis acid; solutions in asymmetrically substituted ethers or in solvent mixtures containing asymmetrically substituted ethers and hydrocarbons, preparation of the solutions according to the invention, and use of the solutions in inorganic, organic, and organometallic synthesis. The invention further relates to solutions of halide compounds of elements of groups 8, 12, and 13 of the periodic table of the elements in asymmetrically substituted ethers, or in mixtures of asymmetrically substituted ethers and hydrocarbons. Lewis acids find numerous applications in the area of chemical synthesis. By adding Lewis acids for example in Diels-Alder reactions, radical-mediated reactions, Friedel-Crafts alkylations or acylations, or aldol reactions, the yield of a synthesis reaction may be increased, and the regio-, enantio-, or diastereoselectivity of the corresponding reaction may optionally be controlled (H. Yamamoto, Lewis Acids in Organic Synthesis, Wiley-VCH, 2000, Volumes 1 and 2, and citations therein). In addition, Lewis acids find applications in the preparation of organometallic compounds, elemental hydrogen compounds (EHX), elemental hydrogen halide compounds, metal element hydrides, and complexed metal hydrides, for example in the preparation of organocopper or organozinc compounds, alane (AIH3), chloroalanes (AIHXCI(3_X)), zinc borohydride, or lithium aluminum hydride (P. Knochel, P. Jones in Organozinc Reagents (Editors: L. M. Harwood, C. J. Moody), Oxford University Press Inc., New York, 1999, and citations therein; C. Elschenbroich, A. Salzer, Organometallchemie [Organometallic Chemistry], Teubner, 1993, 3rd edition; A. J. Downs, C. R. Pulham, Chem. Soc. Rev. 1994, 175; A. E. Finholt, A. C. Bond, Jr., H. I. Schlesinger, J. Am. Chem. Soc. 1947, 69, 1199). Solutions of Lewis acids have the disadvantage that they decompose upon contact with trace amounts of water, so that the starting materials should have an extremely low water content in order to maximize the content of Lewis acids in the solutions. Halogen-containing Lewis acids are also': frequently used as raw materials for preparing organosubstituted or also chiral Lewis acids. Another field of application is C-C coupling reactions which are catalyzed by Lewis acids (M. Nakamura, S. Ito, K. Matsuo, E. Nakamura, Synlett. 2005, 11, 1794;

Documents

Application Documents

# Name Date
1 8588-CHENP-2012-AbandonedLetter.pdf 2018-07-10
1 8588-CHENP-2012.pdf 2012-10-09
2 8588-CHENP-2012-FER.pdf 2017-12-06
2 8588-CHENP-2012 POWER OF ATTORNEY 08-12-2012.pdf 2012-12-08
3 8588-CHENP-2012 PCT 08-12-2012.pdf 2012-12-08
3 8588-CHENP-2012 CLAIMS 08-12-2012.pdf 2012-12-08
4 8588-CHENP-2012 DISCRIPTION(COMPLETE) 08-12-2012.pdf 2012-12-08
4 8588-CHENP-2012 FORM-5 08-12-2012.pdf 2012-12-08
5 8588-CHENP-2012 FORM-3 08-12-2012.pdf 2012-12-08
5 8588-CHENP-2012 CORRESPONDENCE 08-12-2012.pdf 2012-12-08
6 8588-CHENP-2012 FORM-2 08-12-2012.pdf 2012-12-08
6 8588-CHENP-2012 ENGLISH TRANSLATION 08-12-2012.pdf 2012-12-08
7 8588-CHENP-2012 FORM-1 08-12-2012.pdf 2012-12-08
8 8588-CHENP-2012 FORM-2 08-12-2012.pdf 2012-12-08
8 8588-CHENP-2012 ENGLISH TRANSLATION 08-12-2012.pdf 2012-12-08
9 8588-CHENP-2012 FORM-3 08-12-2012.pdf 2012-12-08
9 8588-CHENP-2012 CORRESPONDENCE 08-12-2012.pdf 2012-12-08
10 8588-CHENP-2012 DISCRIPTION(COMPLETE) 08-12-2012.pdf 2012-12-08
10 8588-CHENP-2012 FORM-5 08-12-2012.pdf 2012-12-08
11 8588-CHENP-2012 CLAIMS 08-12-2012.pdf 2012-12-08
11 8588-CHENP-2012 PCT 08-12-2012.pdf 2012-12-08
12 8588-CHENP-2012-FER.pdf 2017-12-06
12 8588-CHENP-2012 POWER OF ATTORNEY 08-12-2012.pdf 2012-12-08
13 8588-CHENP-2012.pdf 2012-10-09
13 8588-CHENP-2012-AbandonedLetter.pdf 2018-07-10

Search Strategy

1 8588_05-12-2017.pdf