Abstract: An orally deliverable pharmaceutical composition comprises a drug-carrier system having a Bcl-2 family protein inhibitory compound, e.g., ABT-263, in solution in a substantially non-aqueous carrier that comprises at least one phospholipid and a pharmaceutically acceptable solubilizing agent. The composition is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.
| # | Name | Date |
|---|---|---|
| 1 | 7762-delnp-2011-Abstract.pdf | 2012-03-28 |
| 1 | 7762-delnp-2011-Correspondence Others-(21-10-2011).pdf | 2011-10-21 |
| 2 | 7762-delnp-2011-Claims.pdf | 2012-03-28 |
| 2 | 7762-delnp-2011-Assignment-(21-10-2011).pdf | 2011-10-21 |
| 3 | 7762-delnp-2011-Correspondence Others.pdf | 2012-03-28 |
| 3 | 7762-delnp-2011-Correspondence Others-(19-03-2012).pdf | 2012-03-19 |
| 4 | 7762-delnp-2011-Description (Complete).pdf | 2012-03-28 |
| 4 | 7762-delnp-2011-GPA.pdf | 2012-03-28 |
| 5 | 7762-delnp-2011-Form-5.pdf | 2012-03-28 |
| 5 | 7762-delnp-2011-Drawings.pdf | 2012-03-28 |
| 6 | 7762-delnp-2011-Form-3.pdf | 2012-03-28 |
| 6 | 7762-delnp-2011-Form-1.pdf | 2012-03-28 |
| 7 | 7762-delnp-2011-Form-2.pdf | 2012-03-28 |
| 8 | 7762-delnp-2011-Form-3.pdf | 2012-03-28 |
| 8 | 7762-delnp-2011-Form-1.pdf | 2012-03-28 |
| 9 | 7762-delnp-2011-Form-5.pdf | 2012-03-28 |
| 9 | 7762-delnp-2011-Drawings.pdf | 2012-03-28 |
| 10 | 7762-delnp-2011-Description (Complete).pdf | 2012-03-28 |
| 10 | 7762-delnp-2011-GPA.pdf | 2012-03-28 |
| 11 | 7762-delnp-2011-Correspondence Others-(19-03-2012).pdf | 2012-03-19 |
| 11 | 7762-delnp-2011-Correspondence Others.pdf | 2012-03-28 |
| 12 | 7762-delnp-2011-Claims.pdf | 2012-03-28 |
| 12 | 7762-delnp-2011-Assignment-(21-10-2011).pdf | 2011-10-21 |
| 13 | 7762-delnp-2011-Correspondence Others-(21-10-2011).pdf | 2011-10-21 |
| 13 | 7762-delnp-2011-Abstract.pdf | 2012-03-28 |