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"Lipid Formulation Of Apoptosis Promoter"

Abstract: An orally deliverable pharmaceutical composition comprises a drug-carrier system having a Bcl-2 family protein inhibitory compound, e.g., ABT-263, in solution in a substantially non-aqueous carrier that comprises at least one phospholipid and a pharmaceutically acceptable solubilizing agent. The composition is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
10 October 2011
Publication Number
52/2012
Publication Type
INA
Invention Field
TRADITIONAL KNOWLEDGE BIOTECHNOLOGY
Status
Email
Parent Application

Applicants

ABBOTT LABORATORIES
100 ABBOTT PARK ROAD, ABBOTT PARK, ILLINOIS 60064, U.S.A.

Inventors

1. DAVID PAUL
858 BECK ROAD, LINDENHURST, ILLINOIS 60046, U.S.A.
2. FICKES MICHAEL
2311 RIDGEWAY AVENUE, EVANSTON, ILLINOIS 60201, U.S.A.
3. FISCHER CRISTINA
2821 NORTH AUGUSTA DRIVE, WADSWORTH, ILLINOIS 60083, U.S.A.
4. HAIGHT ANTHONY R.
40381 REED COURT, WADSWORTH, ILLINOIS 60083, U.S.A.
5. HEEMSTRA KATHERINE
641 WEST GRAND AVENUE, APT. 4, CHICAGO, ILLINOIS 60654, U.S.A.
6. MARSH KENNAN
1499 MCKINLEY ROAD, LAKE FOREST, ILLINOIS 60045, U.S.A.
7. MAYER PETER
1117 AVALON LANE, LIBERTYVILLE, ILLINOIS 60048, U.S.A.
8. RUBIN VITALY
9802 NORTH GRACE AVENUE, NILES, ILLINOIS 60714, U.S.A.
9. SANZGIRI YESHWANT
1323 DEER RUN, GURNEE, ILLINOIS 60031, U.S.A.
10. SCHMITT ERIC
319 EVERGREEN COURT, LIBERTYVILLE, ILLINOIS 60048, U.S.A.
11. TONG PING
6152 INDIAN TRAIL, GURNEE, ILLINOIS 60031, U.S.A.
12. ZHOU DELIANG
107 ALEXANDRIA DRIVE, VERNON HILLS, ILLINOIS 60061, U.S.A.

Specification

Documents

Application Documents

# Name Date
1 7762-delnp-2011-Abstract.pdf 2012-03-28
1 7762-delnp-2011-Correspondence Others-(21-10-2011).pdf 2011-10-21
2 7762-delnp-2011-Claims.pdf 2012-03-28
2 7762-delnp-2011-Assignment-(21-10-2011).pdf 2011-10-21
3 7762-delnp-2011-Correspondence Others.pdf 2012-03-28
3 7762-delnp-2011-Correspondence Others-(19-03-2012).pdf 2012-03-19
4 7762-delnp-2011-Description (Complete).pdf 2012-03-28
4 7762-delnp-2011-GPA.pdf 2012-03-28
5 7762-delnp-2011-Form-5.pdf 2012-03-28
5 7762-delnp-2011-Drawings.pdf 2012-03-28
6 7762-delnp-2011-Form-3.pdf 2012-03-28
6 7762-delnp-2011-Form-1.pdf 2012-03-28
7 7762-delnp-2011-Form-2.pdf 2012-03-28
8 7762-delnp-2011-Form-3.pdf 2012-03-28
8 7762-delnp-2011-Form-1.pdf 2012-03-28
9 7762-delnp-2011-Form-5.pdf 2012-03-28
9 7762-delnp-2011-Drawings.pdf 2012-03-28
10 7762-delnp-2011-Description (Complete).pdf 2012-03-28
10 7762-delnp-2011-GPA.pdf 2012-03-28
11 7762-delnp-2011-Correspondence Others-(19-03-2012).pdf 2012-03-19
11 7762-delnp-2011-Correspondence Others.pdf 2012-03-28
12 7762-delnp-2011-Claims.pdf 2012-03-28
12 7762-delnp-2011-Assignment-(21-10-2011).pdf 2011-10-21
13 7762-delnp-2011-Correspondence Others-(21-10-2011).pdf 2011-10-21
13 7762-delnp-2011-Abstract.pdf 2012-03-28