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Medicinal Composition Comprising Diamino Heterocyclic Carboxamide Compound As Active Ingredient

Abstract: [Problem] To provide: a medicinal composition for treating an AXL related cancer; in another embodiment a medicinal composition for treating a cancer with high expression of AXL; and in still another embodiment a medicinal composition for treating a cancer that has acquired resistance through activation of AXL against anticancer agent therapy. [Solution] As the results of an examination on compounds having AXL inhibitory effect the present inventors confirmed that specific diamino heterocyclic carboxamide compounds have AXL inhibitory effect and medicinal compositions comprising such a compound as an active ingredient have therapeutic effect on an AXL related cancer on a cancer with high expression of AXL in another embodiment and on a cancer that has acquired resistance through activation of AXL against anticancer agent therapy in still another embodiment thereby completing the present invention.

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Patent Information

Application #
Filing Date
03 August 2016
Publication Number
36/2016
Publication Type
INA
Invention Field
PHARMACEUTICALS
Status
Email
patent@depenning.com
Parent Application

Applicants

ASTELLAS PHARMA INC.
5 1 Nihonbashi Honcho 2 chome Chuo ku Tokyo 1038411

Inventors

1. EGUCHI Tomohiro
c/o Astellas Pharma Inc. 5 1 Nihonbashi Honcho 2 chome Chuo ku Tokyo 1038411
2. MORI Masamichi
c/o Astellas Pharma Inc. 5 1 Nihonbashi Honcho 2 chome Chuo ku Tokyo 1038411
3. YAMAKI Yoko
c/o Astellas Pharma Inc. 5 1 Nihonbashi Honcho 2 chome Chuo ku Tokyo 1038411

Specification

SOFT COPY ATTACHED IN PDF

Documents

Application Documents

# Name Date
1 Power of Attorney [03-08-2016(online)].pdf 2016-08-03
2 Form 5 [03-08-2016(online)].pdf 2016-08-03
3 Form 3 [03-08-2016(online)].pdf 2016-08-03
4 Form 1 [03-08-2016(online)].pdf 2016-08-03
5 Drawing [03-08-2016(online)].pdf 2016-08-03
6 Description(Complete) [03-08-2016(online)].pdf 2016-08-03
7 Other Patent Document [29-08-2016(online)].pdf 2016-08-29
8 201647026442.pdf 2016-09-17
9 201647026442-Form 1-300816.pdf 2016-09-28
10 201647026442-Correspondence-F1-300816.pdf 2016-09-28
11 Form 3 [01-02-2017(online)].pdf 2017-02-01
12 Form 3 [05-06-2017(online)].pdf 2017-06-05
13 201647026442-FORM 18 [09-11-2017(online)].pdf 2017-11-09
14 201647026442-FORM 3 [20-12-2018(online)].pdf 2018-12-20
15 201647026442-FER.pdf 2019-03-29
16 201647026442-AbandonedLetter.pdf 2019-10-04

Search Strategy

1 Espacenetpatentsearch_25-03-2019.pdf